Title: The 10 Best 5 Star Hotels in South Central Pennsylania - 2025 Updated Prices | Expedia.co.uk [South Central Pennsylania Travel Guide](https://expedia.co.uk/South-Central-Pennsylania.dx6234009)[Hotels in South Central Pennsylania](https://expedia.co.uk/South-Central-Pennsylania-Hotels.d6234009.Travel-Guide-Hotels)[Holiday Rentals in South Central Pennsylania](https://expedia.co.uk/South-Central-Pennsylania-Holiday-Rentals.d6234009.Travel-Guide-HolidayRentals)[Flights to South Central Pennsylania](https://expedia.co.uk/Cheap-Flights-To-South-Central-Pennsylania.d6234009.Travel-Guide-Flights)[South Central Pennsylania Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Central-Pennsylania.d6234009.Car-Hire-Guide)[South Central Pennsylania Holidays](https://expedia.co.uk/South-Central-Pennsylania.d6234009.Holidays-City-Breaks) ![Pennsylvania featuring interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23298-Please-Touch-Museum.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in South Central Pennsylania, Pennsylvania ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Central Pennsylania 5 Star Hotels Tonight [20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6234009&startDate=2025-09-20&endDate=2025-09-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [21 Sept - 22 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6234009&startDate=2025-09-21&endDate=2025-09-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6234009&startDate=2025-09-26&endDate=2025-09-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6234009&startDate=2025-10-03&endDate=2025-10-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Central Pennsylania 5 Star Hotels ![Exterior](https://images.trvl-media.com/lodging/101000000/100660000/100654400/100654371/88366460.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free cooked-to-order breakfast on weekends ](https://images.trvl-media.com/lodging/101000000/100660000/100654400/100654371/6cbb43c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aromatherapy, hot stone massages, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/101000000/100660000/100654400/100654371/d2371f45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Apartment | 1 bedroom, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/101000000/100660000/100654400/100654371/829d2e16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Pause Bed & Breakfast Huntingdon 10/10 Exceptional (1) "Very cozy suite..many personal touches...really fun to have breakfast delivered to our room! Breakfast delicious😊!! Close to historic Downtown Huntington and State Parks.. A little hard to find property in the dark, though. Really enjoyed our stay!!" [](https://www.expedia.co.uk/Huntingdon-Hotels-The-Pause-Bed-Breakfast.h100654371.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-South-Central-Pennsylania-Hotels.s50-0-d6234009.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-South-Central-Pennsylania-Hotels.s50-0-d6234009.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in South Central Pennsylania. ![Hilton Harrisburg](https://images.trvl-media.com/lodging/1000000/20000/10600/10593/b80f6027_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Harrisburg One North Second Street, Harrisburg, PA £125 28 Sept - 29 Sept includes taxes & fees 8.2/10 Very Good! (1,008 reviews) [](https://expedia.co.uk/Harrisburg-Hotels-Hilton-Harrisburg.h10593.Hotel-Information) ![Hotel Gettysburg](https://images.trvl-media.com/lodging/1000000/10000/5700/5647/9883d31c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Gettysburg One Lincoln Square, Gettysburg, PA £120 5 Oct - 6 Oct includes taxes & fees 9.2/10 Wonderful! (1,128 reviews) [](https://expedia.co.uk/Gettysburg-Hotels-Gettysburg-Hotel.h5647.Hotel-Information) ![DoubleTree Resort by Hilton Lancaster](https://images.trvl-media.com/lodging/4000000/3560000/3555000/3554917/e89e7ce4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### DoubleTree Resort by Hilton Lancaster 2400 Willow Street Pike, Lancaster, PA £97 5 Oct - 6 Oct includes taxes & fees 8.8/10 Excellent! (1,004 reviews) [](https://expedia.co.uk/Lancaster-Hotels-DoubleTree-Resort-By-Hilton-Lancaster.h3554917.Hotel-Information) Still don't see what you're looking for? [See all properties in South Central Pennsylania.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025®ionId=6234009&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025®ionId=6234009&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025®ionId=6234009&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025®ionId=6234009&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025®ionId=6234009&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025®ionId=6234009&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about South Central Pennsylania Explore plenty to see and do in South Central Pennsylania—sports teams, camping and popular sights like Hersheypark. [See all hotels in South Central Pennsylania](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-04&endDate=2025-10-05&adults=2®ionId=6234009) ![Pennsylvania featuring interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23298-Please-Touch-Museum.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top South Central Pennsylania Hotel Reviews ## Find out more about South Central Pennsylania ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [1 Star Hotels in Central Pennsylvania](https://www.expedia.co.uk/1Star-Central-Pennsylvania-Hotels.s10-0-d6057564.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Great Valley](https://www.expedia.co.uk/2Star-Great-Valley-Hotels.s20-0-d713506193989160960.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Pennsylvania Dutch Country](https://www.expedia.co.uk/2Star-Pennsylvania-Dutch-Country-Hotels.s20-0-d553248635975749185.Travel-Guide-Filter-Hotels) - 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