A coastal town with colorful buildings, a mountain range in the background, and boats in the water.

Compare and book 5 Star hotels in Samos, North Aegean Islands

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Check availability on Samos 5 Star Hotels

Tonight
23 Sept - 24 Sept
Tomorrow
24 Sept - 25 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Samos 5-star hotels

A modern resort with a central pool, lounge areas, and mountain views.
A bar area with a wooden counter and stools.
A beachside resort with outdoor seating areas, umbrellas, and a view of the sea.
A spa area with two massage tables, a stone floor, and a bamboo partition.

1. Casa Cook Samos

Casa Cook Samos
Samos
United States
ercan
£189
includes taxes & fees
16 Oct - 17 Oct
Casa Cook Samos
A beach with rows of beige lounge chairs and umbrellas, a clear sky, and a calm sea with a distant mountain.
A modern kitchen with a central island, pendant lighting, and a tiled backsplash.
A coastal hotel with a swimming pool, surrounded by greenery and overlooking the sea.
A beachside lounge with white umbrellas and beige lounge chairs, a wooden deck, and a view of the sea and a pier in the background.

2. Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
United Kingdom
Zafer
£152
includes taxes & fees
28 Sept - 29 Sept
Doryssa Seaside Resort
A row of wooden beach umbrellas with white cushions on a sandy beach, overlooking the sea.
A beach with rows of sunbeds and thatched umbrellas, a clear blue sea, and mountains in the background.
A covered outdoor seating area with wooden flooring, white cushioned chairs, and tables.
A modern bedroom with a bed, bedside tables, a desk, and a view of the sea.

3. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
Germany
Artsem
£141
includes taxes & fees
10 Oct - 11 Oct
Proteas Blu Resort - Adults Only
An infinity pool with lounge chairs and a view of a coastal town.
A modern multi-story building with a landscaped courtyard, featuring a mix of flat and sloped roofs, and a variety of plants and trees.
A modern interior with a dark wood reception desk, a sofa, a large abstract painting, and a potted plant.
A bar area with stools, a counter, and bottles.

4. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
£208
includes taxes & fees
23 Oct - 24 Oct
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Samos.
Hydrele Beach Hotel

Hydrele Beach Hotel

Potokaki beach, Pythagorion Samos Samos island
£98
28 Sept - 29 Sept
includes taxes & fees
8.2/10 Very good! (81 reviews)
Hydrele Beach Hotel
Doryssa Theorem Hotel

Doryssa Theorem Hotel

Pythagoreio Samos Samos Island
£100
12 Oct - 13 Oct
includes taxes & fees
Doryssa Theorem Hotel
Samian Mare Hotel Suites & Spa

Samian Mare Hotel Suites & Spa

Kanari 123 Samos Samos Island
£79
27 Sept - 28 Sept
includes taxes & fees
9.2/10 Wonderful! (37 reviews)
Samian Mare Hotel Suites & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Samos

Explore ancient ruins at the Heraion sanctuary, then cool off at pristine Tsamadou Beach with its crystal-clear waters. Hike through lush forests to reach Potami Waterfalls, where natural swimming pools offer refreshing breaks from the Mediterranean sun.

See all hotels in Samos
A coastal town with colorful buildings, a mountain range in the background, and boats in the water.

Top Samos Hotel Reviews

Doryssa Seaside Resort

Doryssa Seaside Resort

8/10 Good
"Very good, friendly place"
Zafer 3-night trip
Posted 1 month ago
Doryssa Seaside Resort

Find out more about Samos

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Samos?
The amount you pay for a 5-star hotel in Samos depends on things like when you want to go and the length of your getaway. Our top tip for landing an awesome deal? Use our pricing filters to compare all of the available accommodation for your chosen dates.
  • Search for the lowest price per night from £79
What makes a hotel 5 stars in Samos?
From gourmet restaurants and 24-hour fitness centres to pools and deluxe bedding, the 5-star experience in Samos is all about indulgence and comfort. But it takes more than just top-notch perks to earn a 5-star rating. Hotels also have to provide extraordinary guest-focused services like beauty treatments, on-site laundry and dry cleaning and concierge services.
Are there any 5-star all-inclusive resorts in Samos?
Our filter tool is the quickest way to find exactly what you want. Select "5-star" and "All inclusive" to see the most upscale resorts in Samos where your meals, lodging, entertainment and activities are included in the price. At these getaways, your trip is pure indulgence from the moment you arrive.

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