Photo by Andrew Hershfeld
Compare and book 5 Star hotels in Northeast Missouri, Missouri
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Northeast Missouri 5 Star Hotels
Our top choices for Northeast Missouri 5-star hotels
8.8 out of 10, Excellent, (3,246 reviews)
"Good place to stay and relax."
RAJA
The price is £88
includes taxes & fees
26 Jul - 27 Jul
7.4 out of 10, Good, (1,611 reviews)
"Good place to stay"
Jeremy
The price is £69
includes taxes & fees
5 Jul - 6 Jul
9.0 out of 10, Wonderful, (1,978 reviews)
"Super convenient location, friendly staff, cool decor! Will definitely stay here again."
Lindsay
The price is £128
includes taxes & fees
1 Jul - 2 Jul
8.0 out of 10, Very good, (823 reviews)
"Our room was clean water was hot for showers and the staff was so nice."
Pamela
The price is £81
includes taxes & fees
2 Jul - 3 Jul
9.2 out of 10, Wonderful, (1,632 reviews)
"Would stay again in a heartbeat!"
Austin
The price is £91
includes taxes & fees
29 Jun - 30 Jun
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio HotelDowntown St. Louis
8.8 out of 10, Excellent, (1,314 reviews)
"The staff could not have been nicer even holding our luggage before and after checkout. The beds were super comfy and the rooms extra spacious with a living room area separate from the sleeping space. And just a short walk to Busch Stadium and the arch!!"
Cherie
The price is £90
includes taxes & fees
9 Jul - 10 Jul
8.2 out of 10, Very good, (1,009 reviews)
"The room was nice and the staff was friendly. Perfect spot to stay if you’re going out on the town for the night."
Jenna
The price is £137
includes taxes & fees
17 Jul - 18 Jul
7.6 out of 10, Good, (1,176 reviews)
"Beautiful hotel"
Zoobin
The price is £155
includes taxes & fees
17 Jul - 18 Jul
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Northeast Missouri.
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
The price is £120 per night from 9 Jul to 10 Jul
£120
9 Jul - 10 Jul
includes taxes & fees
8.4/10 Very good! (1,100 reviews)
Still don't see what you're looking for?
See all properties in Northeast Missouri.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Northeast Missouri
Great live music, sports teams and popular sights from Six Flags St. Louis to St. Louis Zoo—explore Northeast Missouri, a family-friendly destination also known for its theatres.
Top Northeast Missouri Hotel Reviews
Find out more about Northeast Missouri
Frequently asked questions
Explore a world of travel with Expedia
- 5 Star Hotels in Chesterfield
- 5 Star Hotels in Lake Ozark
- Cairo Hotels
- Callao Hotels
- Canton Hotels
- Centralia Hotels
- Clark Hotels
- Hotels near Cooper's Oak Winery
- Downing Hotels
- Edina Hotels
- Ethel Hotels
- Gibbs Hotels
- Gay-Friendly Hotels in Hannibal
- Hotels with Indoor Pools in Hannibal
- Hannibal Hotels
- Holliday Hotels
- Hunnewell Hotels
- Huntsville Hotels
- Hurdland Hotels
- Kahoka Hotels
- Gay-Friendly Hotels in Kirksville
- Kirksville Hotels
- La Grange Hotels
- La Plata Hotels
- Hotels near La Plata Station
- Lentner Hotels
- Lewistown Hotels
- Macon Hotels
- Marceline Hotels
- Hotels near Mark Twain State Park
- Memphis Hotels
- Apartments in Moberly
- Moberly Hotels
- Monroe City Hotels
- New Cambria Hotels
- New London Hotels
- Novinger Hotels
- Palmyra Hotels
- Paris Hotels
- Perry Hotels
- Renick Hotels
- Hotels near Rothwell Park
- Pet-Friendly Hotels in Rutledge
- Rutledge Hotels
- Saverton Hotels
- Shelbina Hotels
- Shelbyville Hotels
- Stoutsville Hotels
- Taylor Hotels
- West Quincy Hotels
- Flights to Gibbs
- Flights to Hannibal
- Flights to Holliday
- Flights to Kirksville
- Flights to Macon
- Flights from Ethel
- Flights from Kirksville
- Flights from Palmyra
- Flights from Hunnewell
- Flights from Novinger
- Flights from Gibbs
- Flights from Goss
- Flights from Greentop
- Flights from Baring
- Flights from Queen City
- Flights from Lewis County
- Flights from Scotland County
- Flights from Monroe County
- Flights from Adair County
- Flights from Kahoka
- Flights from La Plata
- Flights from Macon
- Flights from Hannibal
- Flights from Maywood
- Flights from Allentown (ABE) to Kirksville (IRK)
- Flights from Champaign (CMI) to Kirksville (IRK)
- Flights from Dubuque (DBQ) to Kirksville (IRK)
- Flights from Lazaro Cardenas (LZC) to Kirksville (IRK)
- Flights from Manchester (MAN) to Kirksville (IRK)
- Flights from Chicago (ORD) to Kirksville (IRK)
- Flights from St. Louis (STL) to Kirksville (IRK)
- Flights from Boulder (WBU) to Kirksville (IRK)