Title: The 10 Best 5 Star Hotels in Lexington - Salisbury - 2026 Updated Prices | Expedia.co.uk [Lexington - Salisbury Travel Guide](https://expedia.co.uk/Lexington-Salisbury.dx6058382)[Hotels in Lexington - Salisbury](https://expedia.co.uk/Lexington-Salisbury-Hotels.d6058382.Travel-Guide-Hotels)[Holiday Rentals in Lexington - Salisbury](https://expedia.co.uk/Lexington-Salisbury-Holiday-Rentals.d6058382.Travel-Guide-HolidayRentals)[Flights to Lexington - Salisbury](https://expedia.co.uk/Cheap-Flights-To-Lexington-Salisbury.d6058382.Travel-Guide-Flights)[Lexington - Salisbury Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lexington-Salisbury.d6058382.Car-Hire-Guide)[Lexington - Salisbury Holidays](https://expedia.co.uk/Lexington-Salisbury.d6058382.Holidays-City-Breaks) ![Downtown Salisbury has several painted pianos set up for people to enjoy and play.](https://images.trvl-media.com/place/9927/f7cdbfac-6224-4f24-9859-debdf61f38fd.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle James # Compare and book 5 Star hotels in Lexington - Salisbury, North Carolina - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lexington - Salisbury 5 Star Hotels Tonight [18 Dec - 19 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6058382&startDate=2025-12-18&endDate=2025-12-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6058382&startDate=2025-12-19&endDate=2025-12-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6058382&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6058382&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Lexington-Salisbury-Hotels.s50-0-d6058382.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Lexington-Salisbury-Hotels.s50-0-d6058382.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lexington - Salisbury. ![DoubleTree by Hilton Greensboro Airport](https://images.trvl-media.com/lodging/1000000/180000/180000/179947/82545d4c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### DoubleTree by Hilton Greensboro Airport 6426 Burnt Poplar Road Greensboro NC £68 28 Dec - 29 Dec includes taxes & fees 8.8/10 Excellent! (898 reviews) [](https://expedia.co.uk/Greensboro-Hotels-Fairview-Inn-Airport.h179947.Hotel-Information) ![Hilton Charlotte University Place](https://images.trvl-media.com/lodging/1000000/10000/5500/5442/a3ad89a7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Charlotte University Place 8629 J M Keynes Dr Charlotte NC £91 28 Dec - 29 Dec includes taxes & fees 8.6/10 Excellent! (1,240 reviews) [](https://expedia.co.uk/Charlotte-Hotels-Hilton-Charlotte-University-Place.h5442.Hotel-Information) ![Grandover Resort & Spa, a Wyndham Grand Hotel](https://images.trvl-media.com/lodging/1000000/210000/200800/200742/b7995aac_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Grandover Resort & Spa, a Wyndham Grand Hotel 1000 Club Rd Greensboro NC £165 2 Jan - 3 Jan 2026 includes taxes & fees 9.2/10 Wonderful! (1,002 reviews) [](https://expedia.co.uk/Greensboro-Hotels-Grandover-Resort-Spa.h200742.Hotel-Information) Still don't see what you're looking for? [See all properties in Lexington - Salisbury.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025®ionId=6058382&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025®ionId=6058382&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025®ionId=6058382&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025®ionId=6058382&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025®ionId=6058382&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025®ionId=6058382&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Lexington - Salisbury and related destinations - Lexington - Salisbury - Lima - Russellville - Hinesville - Ottumwa Experience the family-friendly area of Lexington - Salisbury—wineries, shopping and sights from Richard Childress Vineyards to High Rock Lake. [See all hotels in Lexington - Salisbury](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02&adults=2®ionId=6058382) ![Downtown Salisbury has several painted pianos set up for people to enjoy and play.](https://images.trvl-media.com/place/9927/f7cdbfac-6224-4f24-9859-debdf61f38fd.jpg?impolicy=fcrop&w=300&h=400&p=1&q=high) Photo by Michelle James ## Top Lexington - Salisbury Hotel Reviews ## Find out more about Lexington - Salisbury ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Lexington - Salisbury? > - Search for the lowest price per night from £68 ### What makes a hotel 5 stars in Lexington - Salisbury? ### Are there any 5-star all-inclusive resorts in Lexington - Salisbury? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [3 Star Hotels in Durham ](https://www.expedia.co.uk/3Star-Durham-Hotels.s30-0-d6049.Travel-Guide-Filter-Hotels) - 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