A marshy landscape with water, trees, and a distant city skyline.

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Check availability on Ladys Island 5 Star Hotels

Tonight
6 Sept - 7 Sept
Tomorrow
7 Sept - 8 Sept
Next weekend
11 Sept - 13 Sept
In two weeks
18 Sept - 20 Sept

Our top choices for Ladys Island 5-star hotels

A view through large windows of a landscaped garden with a circular stone feature, surrounded by potted plants.
A restaurant with a long bar, wooden flooring, and a fireplace. Tables are set with glasses and cutlery.
A spacious living room with a large sofa, a coffee table, and a fireplace. There are large windows with blinds, a ceiling fan, and a stone wall.
A large house with a covered porch, a chimney, and a driveway.

1. Montage Palmetto Bluff

Montage Palmetto Bluff
Palmetto Bluff
United States
P Randall
£514
includes taxes & fees
7 Sept - 8 Sept
Montage Palmetto Bluff
An outdoor patio area with seating, umbrellas, and a view of a golf course.
A spacious lobby with a grand chandelier, a piano, and a central floral arrangement.
A hotel with a central courtyard featuring a fountain, outdoor seating, and palm trees.
A golf course with a lighthouse, water, and boats in the background.

2. The Inn & Club at Harbour Town

The Inn & Club at Harbour Town
Sea Pines
United States
Lisa
£334
includes taxes & fees
20 Sept - 21 Sept
The Inn & Club at Harbour Town
A two-story white colonial-style building with a central entrance, columns, and a balcony on the upper floor.
A spacious bathroom with a large bathtub, wooden paneling, and a glass table with a chair.
A traditional living room with wooden paneled walls, a staircase, and two sofas.
A traditional living room with a fireplace, two sofas, a coffee table, and a bookshelf.

3. Anchorage 1770

Anchorage 1770
Historic District
United States
Jeanne
£194
includes taxes & fees
23 Sept - 24 Sept
Anchorage 1770
A historic building with a covered porch and a brick pathway.
A cozy room with a gray sofa, a chair, and a small table with books and a tray.
A spacious patio with a dining area, wicker furniture, and a view of trees.
A modern bedroom with a four-poster bed, a large window with a view of trees, and a unique ceiling light fixture.

4. Montage Palmetto Bluff Residences

Montage Palmetto Bluff Residences
Palmetto Bluff
United States
john j
£1,180
includes taxes & fees
7 Oct - 8 Oct
Montage Palmetto Bluff Residences
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Ladys Island.
Hilton Beachfront Resort & Spa Hilton Head Island

Hilton Beachfront Resort & Spa Hilton Head Island

1 Hotel Circle Hilton Head Island SC
£204
15 Sept - 16 Sept
includes taxes & fees
Hilton Beachfront Resort & Spa Hilton Head Island
Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

130 Shipyard Drive Hilton Head Island SC
£234
13 Sept - 14 Sept
includes taxes & fees
Sonesta Resort Hilton Head Island
Beach House Resort Hilton Head

Beach House Resort Hilton Head

1 South Forest Beach Drive Hilton Head Island SC
£165
15 Sept - 16 Sept
includes taxes & fees
8.6/10 Excellent! (1,480 reviews)
Beach House Resort Hilton Head
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Ladys Island

Check out the local area in Ladys Island—home to attractions like Coosaw Island and Cat Island Driving Range.

See all hotels in Ladys Island
A sunset over a calm water body with reflections of the sky, surrounded by grassy areas and distant trees.
Photo by Michael Schuier

Top Ladys Island Hotel Reviews

Montage Palmetto Bluff

Montage Palmetto Bluff

10/10 Excellent
"This weekend was my second visit to the Montage Palmetto. The first time was in February, where all I wanted to do was get a change of scenery from Charleston and do some cycling. That weekend was quiet and calm, and the cycling was superb. This time - the Labor Day weekend - the weather was much warmer, the sunshine was bright, and all the pools were open. The water was refreshing, the bar nearby provided the necessary Negronis, and I was able to play 18 holes at the nearby May River course, complete with a caddie and a full walk. We visited Buffalo's a few times for breakfast and dinner (the staff will golf cart you to and from the hotel) and once at Octagon, which is in the hotel itself. Everything was perfect. I will come back, especially since it's just a 2 hour drive away, and with golfing that rivals - if not beats - Kiawah. Thank you. Christophe"
Christophe 2-night trip
Posted less than an hour ago
Montage Palmetto Bluff

Find out more about Ladys Island

Frequently asked questions

What are the best 5-star hotels in Ladys Island?
Experience top-class amenities and impeccable service at Anchorage 1770. Located around the Beaufort neighbourhood of Ladys Island, this 5-star hotel is the preferred choice for many based on reviews by Expedia's customers.
How much does it cost to stay in a 5-star hotel in Ladys Island?
You can find many different pricing options for 5-star hotels in Ladys Island on Expedia. The amount you pay will depend on when you plan to travel, trip length and other factors. Compare available properties for your desired dates and make use of our pricing and other filters to discover the perfect upscale stay.
  • Search for the lowest price per night from £165
What makes a hotel 5 stars in Ladys Island?
Exemplary guest service is the defining feature of every 5-star hotel in Ladys Island. From the moment you enter the lobby, staff attend to your every whim, whether offering luggage assistance and storage or providing in-room massages. On top of that, hotels must feature top-rate amenities to meet the standard for a 5-star rating. These can include luxury bathrobes, saunas or spas, swimming pools, fine dining kitchens and knowledgeable concierge.

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