A marshy landscape with water, trees, and a distant city skyline.

Compare and book 5 Star hotels in Ladys Island, Beaufort

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Check availability on Ladys Island 5 Star Hotels

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Ladys Island 5-star hotels

A view through large windows of a landscaped garden with a circular stone feature, surrounded by potted plants.
A restaurant with a long bar, wooden flooring, and a fireplace. Tables are set with glasses and cutlery.
A covered outdoor seating area with wicker furniture and large windows overlooking a garden.
A large house with a covered porch, a chimney, and a driveway.

1. Montage Palmetto Bluff

Montage Palmetto Bluff
Palmetto Bluff
United States
P Randall
£561
includes taxes & fees
18 Nov - 19 Nov
Montage Palmetto Bluff
An outdoor patio area with seating, umbrellas, and a view of a golf course.
A hotel with a central courtyard featuring a fountain, outdoor seating, and palm trees.
A restaurant with multiple dining tables and chairs, a bar area with a television, and a variety of bottles and glasses on shelves.
A spacious lobby with a grand chandelier, a piano, and a central floral arrangement.

2. The Inn & Club at Harbour Town

The Inn & Club at Harbour Town
Sea Pines
United States
Lisa
£330
includes taxes & fees
2 Nov - 3 Nov
The Inn & Club at Harbour Town
A two-story white colonial-style building with a central entrance, columns, and a balcony on the upper floor.
A traditional living room with a fireplace, two sofas, a coffee table, and a bookshelf.
A traditional living room with wooden paneled walls, a staircase, and two sofas.
A spacious bathroom with a large bathtub, wooden paneling, and a glass table with a chair.

3. Anchorage 1770

Anchorage 1770
Historic District
United States
Steve
£208
includes taxes & fees
1 Nov - 2 Nov
Anchorage 1770
A historic building with a covered porch and a brick pathway.
A modern bedroom with a four-poster bed, a large window with a view of trees, and a unique ceiling light fixture.
A spacious patio with a dining area, wicker furniture, and a view of trees.
A cozy room with a gray sofa, a chair, and a small table with books and a tray.

4. Montage Palmetto Bluff Residences

Montage Palmetto Bluff Residences
Palmetto Bluff
United States
john j
£1,338
includes taxes & fees
19 Nov - 20 Nov
Montage Palmetto Bluff Residences
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Ladys Island.
Hilton Beachfront Resort & Spa Hilton Head Island

Hilton Beachfront Resort & Spa Hilton Head Island

1 Hotel Circle Hilton Head Island SC
£152
17 Nov - 18 Nov
includes taxes & fees
8.4/10 Very good! (1,691 reviews)
Hilton Beachfront Resort & Spa Hilton Head Island
Beach House Resort Hilton Head

Beach House Resort Hilton Head

1 South Forest Beach Drive Hilton Head Island SC
£164
1 Nov - 2 Nov
includes taxes & fees
Beach House Resort Hilton Head
Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

130 Shipyard Drive Hilton Head Island SC
£173
3 Nov - 4 Nov
includes taxes & fees
Sonesta Resort Hilton Head Island
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Ladys Island

Check out the local area in Ladys Island—home to attractions like Coosaw Island and Cat Island Driving Range.

See all hotels in Ladys Island
A sunset over a water body with a wooden fence and trees with Spanish moss.
Photo by Michael Schuier

Top Ladys Island Hotel Reviews

Find out more about Ladys Island

Frequently asked questions

What are the best 5-star hotels in Ladys Island?
Experience top-class amenities and impeccable service at Anchorage 1770. Located around the Beaufort neighbourhood of Ladys Island, this 5-star hotel is the preferred choice for many based on reviews by Expedia's customers.
How much does it cost to stay in a 5-star hotel in Ladys Island?
You can find many different pricing options for 5-star hotels in Ladys Island on Expedia. The amount you pay will depend on when you plan to travel, trip length and other factors. Compare available properties for your desired dates and make use of our pricing and other filters to discover the perfect upscale stay.
  • Search for the lowest price per night from £152
What makes a hotel 5 stars in Ladys Island?
Exemplary guest service is the defining feature of every 5-star hotel in Ladys Island. From the moment you enter the lobby, staff attend to your every whim, whether offering luggage assistance and storage or providing in-room massages. On top of that, hotels must feature top-rate amenities to meet the standard for a 5-star rating. These can include luxury bathrobes, saunas or spas, swimming pools, fine dining kitchens and knowledgeable concierge.

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