A busy urban street with pedestrians, cars, and historic buildings.

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Check availability on Cambridge 5 Star Hotels

Tonight
8 Sept - 9 Sept
Tomorrow
9 Sept - 10 Sept
This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

Our top choices for Cambridge 5-star hotels

3 restaurants; breakfast, lunch, dinner and brunch served
Exterior
3 restaurants; breakfast, lunch, dinner and brunch served
Staircase

1. The Charles Hotel

The Charles Hotel
West Cambridge
United States
Rodney
£378
includes taxes & fees
2 Oct - 3 Oct
The Charles Hotel
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Cambridge.
Hyatt Regency Boston/Cambridge

Hyatt Regency Boston/Cambridge

575 Memorial Drive Cambridge MA
£163
20 Sept - 21 Sept
includes taxes & fees
9/10 Wonderful! (2,632 reviews)
Hyatt Regency Boston/Cambridge
The Royal Sonesta Boston

The Royal Sonesta Boston

40 Edwin H. Land Boulevard Cambridge MA
£227
20 Sept - 21 Sept
includes taxes & fees
8.8/10 Excellent! (1,977 reviews)
The Royal Sonesta Boston
Boston Marriott Cambridge

Boston Marriott Cambridge

Two Cambridge Center, 50 Broadway Cambridge MA
£232
20 Sept - 21 Sept
includes taxes & fees
8.8/10 Excellent! (1,001 reviews)
Boston Marriott Cambridge
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Cambridge

Harvard's iconic red-brick campus and MIT's cutting-edge architecture create a vibrant university town worth exploring. Stroll along the Charles River in the morning, then browse independent bookshops and cafés in Harvard Square when students fill the pavements.

See all hotels in Cambridge
A historic brick building with a large arched window and a tower.

Top Cambridge Hotel Reviews

Encore Boston Harbor

Encore Boston Harbor

10/10 Excellent
"All great! Service, location, everything Was great"
Giuseppe 2-night trip
Posted 1 hour ago
Encore Boston Harbor
Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport

8/10 Good
"Great experience. Clean room. Only downside was that you could hear everything going on in the hallway outside your room."
Heather 3-night trip
Posted 2 hours ago
Omni Boston Hotel at the Seaport

Find out more about Cambridge

Frequently asked questions

What are the best 5-star hotels in Cambridge?
Experience 5-star luxuriousness at The Liberty, a Marriott Luxury Collection Hotel, Boston, Mandarin Oriental, Boston or Four Seasons Hotel One Dalton Street, Boston. These are some of the leading accommodation in Cambridge based on Expedia customer reviews. Choose your favourite and enjoy a taste of the good life!
How much does it cost to stay in a 5-star hotel in Cambridge?
How much you pay for a 5-star hotel in Cambridge can vary according to what time of year you travel and how long you plan to be away, among several factors. Use our price per night filter and other search tools to find the best rate on a high-end stay.
  • Search for the lowest price per night from £163
What makes a hotel 5 stars in Cambridge?
Outstanding guest service is integral to every 5-star hotel in Cambridge. From the minute you step through the door, staff cater to your every whim, whether arranging valet parking or providing in-room massage treatments. In addition, hotels must feature superior amenities to meet the standard for a 5-star rating. These can include luxury bathrooms, on-site spa facilities, pools, gastronomic restaurants and knowledgeable concierge.

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