A vineyard with rows of grapevines.

Compare and book 4 Star hotels in Santa Cruz, O'Higgins Region

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Check availability on Santa Cruz 4 Star Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Santa Cruz 4-star hotels

A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.

1. Santa Cruz Plaza

Santa Cruz Plaza
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (378 reviews)
"The service from the staff is immaculate. The properly full of charm and character. The rooms are spacious, clean and comfortable"
United Kingdom
Darren
The price is £85
6 Dec - 7 Dec
Santa Cruz Plaza
A hot tub in a vineyard setting with a wooden deck and a wooden fence in the background.

2. Hotel Cava Colchagua

Hotel Cava Colchagua
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (178 reviews)
"Interesting and beautiful place to stay. Barrel rooms are comfortable. Staff are very pleasant and accomodating. Food at the restaurant was fantastic. Shower was not the best."
Canada
Anonymous traveller
The price is £101
10 Nov - 11 Nov
Hotel Cava Colchagua
Terrace/patio

3. Barrica Lodge

Barrica Lodge
4.0 star property
Santa Cruz
8.0 out of 10, Very good, (1 review)
Barrica Lodge
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Cruz.
Vik Chile

Vik Chile

Valle de Millahue San Vicente O'Higgins
The price is £571 per night from 11 Nov to 12 Nov
£571
11 Nov - 12 Nov
9.2/10 Wonderful! (231 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Cruz

Nestled in the heart of wine country, Santa Cruz invites visitors to taste world-class Colchagua Valley wines at family-owned vineyards. Museum of Colchagua showcases impressive pre-Columbian artefacts while the Plaza de Armas offers local crafts and regional foods on weekends.

See all hotels in Santa Cruz
A vineyard with rows of grapevines, terraced fields, and mountains in the background.

Top Santa Cruz Hotel Reviews

Santa Cruz Plaza

Santa Cruz Plaza

10/10 Excellent
"The service from the staff is immaculate. The properly full of charm and character. The rooms are spacious, clean and comfortable"
Darren 1-night trip
Posted 3 days ago
Santa Cruz Plaza
Hotel Cava Colchagua

Hotel Cava Colchagua

10/10 Excellent
"Excelente y original experiencia boutique Una propuesta realmente innovadora. Se trata de un hotel boutique hermoso cuyas habitaciones están acondicionadas dentro de barricas de roble, muy bien adaptadas y acogedoras. Como sugerencia de mejora, creo que a las habitaciones más grandes les vendría muy bien incluir un perchero y una pequeña mesa con dos sillas para mayor comodidad. Asimismo, en el baño eché de menos una mejor iluminación en el área del espejo. Por lo demás, todo fenomenal. El personal es sumamente amable y siempre está atento a cualquier necesidad. ¡Regresaría sin dudarlo!"
Franco 3-night trip
Posted 3 months ago
Hotel Cava Colchagua

Find out more about Santa Cruz

Frequently asked questions

What are the best 4-star hotels in Santa Cruz?
Expedia travellers enjoy staying at Santa Cruz Plaza. From its handy amenities to its dedicated staff, everything about this 4-star hotel in Santa Cruz is designed to offer a memorable holiday experience.
How much does it cost to stay in a 4-star hotel in Santa Cruz?
With Expedia's handy filter tool, scoring a superb deal on a 4-star hotel in Santa Cruz just got simpler. Start by keying in your chosen arrival date and length of your break. Then sort the results by price and pick a hotel that best matches your budget and style.

  • Search for the lowest price from £571

What's the difference between 5-star and 4-star hotels in Santa Cruz?
Treat yourself to luxury living during your Santa Cruz getaway by staying at a 4-star hotel. As well as featuring upscale accommodation, these properties are usually packed with amenities, including large beds, complimentary bathrobes and plenty more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and special one. 24-hour concierge assistance, elegant décor and world-class dining are only the start of the exclusive services and conveniences you'll likely get access to.