Title: The 10 Best 4 Star Hotels in Mesopotamia - 2025 Updated Prices | Expedia.co.uk

  

[Mesopotamia Travel Guide](https://expedia.co.uk/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.co.uk/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Holiday Rentals in Mesopotamia](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6208836.Travel-Guide-HolidayRentals)[Flights to Mesopotamia](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6208836.Car-Hire-Guide)[Mesopotamia Holidays](https://expedia.co.uk/Mesopotamia.d6208836.Holidays-City-Breaks)

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# Compare and book 4 Star hotels in Mesopotamia, Argentina

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## Check availability on Mesopotamia 4 Star Hotels

Tonight

[20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2025-09-20&endDate=2025-09-21&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[21 Sept - 22 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2025-09-21&endDate=2025-09-22&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2025-09-26&endDate=2025-09-28&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2025-10-03&endDate=2025-10-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Mesopotamia 4 Star Hotels

![Dining](https://images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/36b8ac51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/cfb1c595.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/000bdc72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/53c4a504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Esplendor by Wyndham Savoy Rosario

Rosario Centro

8.6/10

Excellent

(437)

"Excellent hotel Everything very comfortable, and convenient"

£55

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Rosario-Hotels-Esplendor-By-Wyndham-Savoy-Rosario.h2803473.Hotel-Information)

![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/65a9aa22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/ed3d5f57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/6db98c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/ba8eff35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Dazzler by Wyndham Rosario

Rosario

8.8/10

Excellent

(181)

"Good hotel overall"

£49

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Rosario-Hotels-Dazzler-By-Wyndham-Rosario.h20265319.Hotel-Information)

![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/13fc6ccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/f21bc2e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/12ba074c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/903afdd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InterTower Hotel

Santa Fe

8.8/10

Excellent

(202)

"Excelent place to stay."

£57

5 Oct - 6 Oct

[](https://www.expedia.co.uk/Santa-Fe-Hotels-InterTower-Hotel.h9845278.Hotel-Information)

![Casino](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/a75881f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/d7ac2335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/da57c485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/21b37ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Amérian Hotel Casino Gala

Resistencia

9.0/10

Wonderful

(163)

"Great service and attention!. I highly recommend this hotel . "

[](https://www.expedia.co.uk/Resistencia-Hotels-Amerian-Hotel-Casino-Gala.h1197026.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/c5d48d1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/962c6c78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/1dcc67c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food court](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/1ce8f635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Los Silos Hotel

Santa Fe

9.4/10

Exceptional

(25)

"Unique, interesting, and very nice. Staff was outstanding. We will be back soon"

£81

27 Sept - 28 Sept

[](https://www.expedia.co.uk/Santa-Fe-Parana-Hotels-Los-Silos-Hotel.h49086569.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/3b6899cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/6f7f5b2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/0fd9db67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/4000000/3030000/3023900/3023891/6fa88a7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pullman Rosario City Center Hotel

Rosario

8.6/10

Excellent

(272)

"Nice"

[](https://www.expedia.co.uk/Rosario-Hotels-Pullman-Rosario-City-Center-Hotel.h3023891.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/e7b50f9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/c303d064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool, open 9:00 AM to 9:00 PM, pool loungers](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/3f7af7b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/11000000/10640000/10633700/10633627/64dd1add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Puerto Norte Design Hotel

Rosario

9.2/10

Wonderful

(141)

"Nice place "

[](https://www.expedia.co.uk/Rosario-Hotels-Puerto-Norte-Design-Hotel.h10633627.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1740000/1733400/1733362/ba76bcfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1740000/1733400/1733362/e02bcc0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1740000/1733400/1733362/5dea5a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1740000/1733400/1733362/dc589cf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ros Tower Hotel

Rosario Centro

8.6/10

Excellent

(309)

"The breakfast was excellent, the hotel a bit outdated but still great for Rosario."

[](https://www.expedia.co.uk/Rosario-Hotels-Ros-Tower-Hotel.h1733362.Hotel-Information)

![2 bedrooms, premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/9cad496d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Duplex | Living area | 40-inch LED TV with cable channels, Netflix, streaming services](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/1eee7dc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/5f45ac2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Apartment | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/3ee5dbf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Agustín 1 Apart

Parana

9.0/10

Wonderful

(4)

£47

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information)

![41-inch TV with satellite channels](https://images.trvl-media.com/lodging/1000000/90000/82800/82767/05ab0316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![41-inch TV with satellite channels](https://images.trvl-media.com/lodging/1000000/90000/82800/82767/24338ad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Room, 1 Queen Bed | Minibar, in-room safe, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/90000/82800/82767/45dd36ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/90000/82800/82767/54b4cb2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Solans Presidente

Rosario Centro

8.6/10

Excellent

(145)

"Excelente "

[](https://www.expedia.co.uk/Rosario-Hotels-Hotel-Solans-Presidente.h82767.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c114ee3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c58abaf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/3140cd55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/ce029153.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Alondra Casa De Huéspedes

Corrientes

9.2/10

Wonderful

(65)

[](https://www.expedia.co.uk/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/2caaf7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/386d872f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Spa](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/03c0216a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marriott Corrientes Hotel

Corrientes

£93

27 Sept - 28 Sept

[](https://www.expedia.co.uk/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information)

![Standard Room | 1 bedroom, soundproofing, free WiFi](https://images.trvl-media.com/lodging/107000000/106450000/106442400/106442332/21c041c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room | Private kitchen | Full-sized fridge, microwave, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/107000000/106450000/106442400/106442332/54539f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room | Private kitchen | Full-sized fridge, microwave, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/107000000/106450000/106442400/106442332/d7971d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room | 1 bedroom, soundproofing, free WiFi](https://images.trvl-media.com/lodging/107000000/106450000/106442400/106442332/69763b11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apart Hotel Ribera del Baradero

Baradero

£62

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Baradero-Hotels-Apart-Hotel-Ribera-Del-Baradero.h106442332.Hotel-Information)

![City view](https://images.trvl-media.com/lodging/111000000/110110000/110102000/110101965/cb7e701b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Suite, Kitchen, City View | 1 bedroom, premium bedding, down duvets, Select Comfort beds](https://images.trvl-media.com/lodging/111000000/110110000/110102000/110101965/dded7234.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Duplex | 1 bedroom, premium bedding, down duvets, Select Comfort beds](https://images.trvl-media.com/lodging/111000000/110110000/110102000/110101965/e99fcc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Room, Kitchen, City View | Private kitchen | Mini-fridge, espresso maker, electric kettle, griddle](https://images.trvl-media.com/lodging/111000000/110110000/110102000/110101965/31f1c365.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ámbar Suites

Rosario Centro

[](https://www.expedia.co.uk/Rosario-Hotels-Ambar-Suites.h110101965.Hotel-Information)

![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/97000000/96510000/96506400/96506339/ab4ac05a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Room | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/97000000/96510000/96506400/96506339/eb0983a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/97000000/96510000/96506400/96506339/5ed2f5c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/97000000/96510000/96506400/96506339/4d75b5c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HOTEL TERMAS VICTORIA Wellness Spa

Victoria

9.0/10

Wonderful

(2)

"El hotel está ubicado en un lugar muy bueno, muy tranquilo, buenas instalaciones y buena disposición de las mismas, la vista es increíble "

[](https://www.expedia.co.uk/HOTEL-TERMAS-VICTORIA-Spa-Reuniones.h96506339.Hotel-Information)

![Poolside bar](https://images.trvl-media.com/lodging/5000000/4920000/4916900/4916858/b42faffa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4920000/4916900/4916858/4c19ce64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4920000/4916900/4916858/566fd548.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/5000000/4920000/4916900/4916858/d91442d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Pedro Palace Hotel

San Pedro

8.8/10

Excellent

(6)

[](https://www.expedia.co.uk/San-Pedro-Hotels-San-Pedro-Palace-Hotel.h4916858.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/39000000/38240000/38239800/38239705/7f9bf546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/39000000/38240000/38239800/38239705/ede7450f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa, 4 Bedrooms, Private Pool | 4 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38240000/38239800/38239705/825dc588.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/39000000/38240000/38239800/38239705/701cff77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Lua

Gualeguaychú

[](https://www.expedia.co.uk/Gualeguaychu-Hotels-Villa-Lua.h38239705.Hotel-Information)

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## Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mesopotamia.

![Bagú Urbano](https://images.trvl-media.com/lodging/5000000/4390000/4388000/4387932/5e4f0852_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Bagú Urbano

Bolivar 2176, Posadas, Misiones

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=04%2F10%2F2025&endDate=05%2F10%2F2025&selected=4387932&PinnedHotelID=4387932&HadPinnedHotel=true&regionId=6208836)

8.4/10 Very Good! (338 reviews)

[](https://expedia.co.uk/Posadas-Hotels-Hotel-Urbano-Posadas.h4387932.Hotel-Information)

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[Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025&regionId=6208836&star=40&star=40&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025&regionId=6208836&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025&regionId=6208836&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025&regionId=6208836&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=21%2F09%2F2025&endDate=22%2F09%2F2025&regionId=6208836&star=40&star=40&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Mesopotamia

The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

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![Mesopotamia showing a river or creek and forests](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/196000/196544-Mesopotamia.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Mesopotamia Hotel Reviews

![Esplendor by Wyndham Savoy Rosario](//images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/36b8ac51_y.jpg)

### Esplendor by Wyndham Savoy Rosario

10/10 Excellent

"Excellent hotel Everything very comfortable, and convenient"

[](https://expedia.co.uk/Rosario-Hotels-Esplendor-By-Wyndham-Savoy-Rosario.h2803473.Hotel-Information)

![Dazzler by Wyndham Rosario](//images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/65a9aa22_y.jpg)

### Dazzler by Wyndham Rosario

10/10 Excellent

"Todo correcto"

[](https://expedia.co.uk/Rosario-Hotels-Dazzler-By-Wyndham-Rosario.h20265319.Hotel-Information)

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