Title: Mesopotamia Adventure Holidays 2026 | Expedia.co.uk ![](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mesopotamia Adventure Holidays ## Book a Adventure Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top Adventure Mesopotamia Hotels ![Iguazu Grand Resort Spa & Casino](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/afaaa032_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Iguazu Grand Resort Spa & Casino Route 12 Km 1640 Puerto Iguazú Misiones - 17 hours drive from Termas de Federacion Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ... 9/10 Wonderful! (633 reviews) The staff and amenities were amazing. The rooms large and spacious. Reviewed on 15 Mar 2026 [](https://expedia.co.uk/Puerto-Iguazu-Hotels-Iguazu-Grand-Resort-Spa-Casino.h979370.Hotel-Information) ![Hotel das Cataratas, A Belmond Hotel, Iguassu Falls](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/3fe012c0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel das Cataratas, A Belmond Hotel, Iguassu Falls Rodovia Br 469 Km 32 Foz do Iguaçu PR - 17 hours drive from Termas de Federacion Stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff and the property condition ... 9.8/10 Exceptional! (1,003 reviews) You go here for the views of course. The common areas are beautiful. The rooms are 3 star - not 5\. They are worse than a premier inn or a Hampton room - small, shabby and dated. The amenities are not as you’d expect of a 5 star. Not even a plug socket on one side of the bed. The pictures are fixed ... Reviewed on 13 Mar 2026 [](https://expedia.co.uk/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information) ![Gran Melia Iguazú](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/c43a985d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Gran Melia Iguazú Parque Nacional Iguazu Puerto Iguazú Misiones - 17 hours drive from Termas de Federacion Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ... 9.2/10 Wonderful! (1,002 reviews) Wonderful stay in the park Hike to Iguazu falls from hotel Amazing breakfast and bbq Pool was much needed with poolside service Reviewed on 15 Mar 2026 [](https://expedia.co.uk/Puerto-Iguazu-Hotels-Gran-Melia-Iguazu.h454059.Hotel-Information) [See all 513 properties in Mesopotamia](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6208836) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More holidays you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holiday packages](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## More Holiday Ideas [Flights to Mesopotamia ](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[ Mesopotamia Hotels ](https://expedia.co.uk/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[ Mesopotamia Holiday Rentals ](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6208836.Travel-Guide-HolidayRentals)[ Mesopotamia Car Hire ](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6208836.Car-Hire-Guide)[ Mesopotamia Holidays ](https://expedia.co.uk/Mesopotamia.d6208836.Holidays-City-Breaks) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app