Title: Cayos Zapatilla Adults Only Holidays 2025/2026 | Expedia.co.uk ![](https://images.trvl-media.com/place/6246124/962b07b0-9b6f-43f9-a3da-ab98125d9cc6.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Cayos Zapatilla Adults Only Holidays ## Book a Adults Only Hotel + Flight or Car together to unlock savings Photo by Isa - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## 5\* Adults Only holidays in Cayos Zapatilla Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista £1,029 per person 24 Dec - 31 Dec found 17 hours ago Return flight included London (LHR) to Panama City (PTY) 18/10 Exceptional! (4,515 reviews) The location of the hotel Reviewed on 19 Nov 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-31/?FromAirport=LHR&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=3900395&paandie=true&HotelClass=50&dealMarker=j48UxHZ8T8gfKTRL-rsP0-zGvpsddwsFuRIitClzuX4pConEXy7woPfYTmDya458) ![Bristol Panama, a Registry Collection Hotel](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Bristol Panama, a Registry Collection Hotel Bella Vista £1,506 per person 25 Dec - 1 Jan found 1 day ago Return direct flight included London (LHR) to Panama City (PTY) 18.4/10 Exceptional! (1,001 reviews) Super team. Danay always makes my stay wonderful as does the whole team. I go often. Reviewed on 16 Nov 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-25/2026-01-01/?FromAirport=LHR&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=69638&paandie=true&HotelClass=50&dealMarker=QDycZ0z9SblsP5fsFfmmGD716OUIsN98ijEp-D3kvhhO7nxcqCeT7LwnhBXgq-uH) ![Hotel La Compania Del Valle](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/bd071da6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel La Compania Del Valle £1,908 per person 24 Dec - 31 Dec found 17 hours ago Return flight included London (LHR) to Panama City (PTY) 19.6/10 Exceptional! (54 reviews) super nice place i will come back again! Reviewed on 13 Nov 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-31/?FromAirport=LHR&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=111207482&paandie=true&HotelClass=50&dealMarker=j48UxHZ8T8gfKTRL-rsP0-zGvpsddwsFuRIitClzuX4jDFFohHGfsK6ej4VW7emI) Don't see what you're looking for? See all available trips from London to Cayos Zapatilla [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-19/2025-12-26/?FromAirport=LHR&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## More holidays you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## More Holiday Ideas [Flights to Cayos Zapatilla](https://expedia.co.uk/Cheap-Flights-To-Cayos-Zapatilla.d6286134.Travel-Guide-Flights)[Cayos Zapatilla Hotels](https://expedia.co.uk/Cayos-Zapatilla-Hotels.d6286134.Travel-Guide-Hotels)[Cayos Zapatilla Holiday Rentals](https://expedia.co.uk/Cayos-Zapatilla-Holiday-Rentals.d6286134.Travel-Guide-HolidayRentals)[Cayos Zapatilla Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Cayos-Zapatilla.d6286134.Car-Hire-Guide)[Cayos Zapatilla Holidays](https://expedia.co.uk/Cayos-Zapatilla.d6286134.Holidays-City-Breaks) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)