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£565 Cheap Flights from Southampton (SOU) to San Diego (SAN)

View £565 flight on Fri, 2 Oct 2026Opens in a new window

Flight 1

Popular airlines from Southampton (SOU) to San Diego Intl. Airport (SAN)

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Cheap Flights from Southampton (SOU) to San Diego (SAN)

Prices were available within the past 7 days and start at £565 for one-way flights and £713 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

KLM
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£713 Return, found 20 hours ago
£713
Return
found 20 hours ago
Select KLM flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £713 found 20 hours ago
KLM
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£717 Return, found 20 hours ago
£717
Return
found 20 hours ago
Select KLM flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £717 found 20 hours ago
KLM
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£733 Return, found 20 hours ago
£733
Return
found 20 hours ago
Select KLM flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £733 found 20 hours ago
KLM
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£754 Return, found 20 hours ago
£754
Return
found 20 hours ago
Select KLM flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £754 found 20 hours ago
KLM
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£758 Return, found 20 hours ago
£758
Return
found 20 hours ago
Select KLM flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £758 found 20 hours ago
Virgin Atlantic
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£764 Return, found 20 hours ago
£764
Return
found 20 hours ago
Select Virgin Atlantic flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £764 found 20 hours ago
KLM
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£774 Return, found 20 hours ago
£774
Return
found 20 hours ago
Select KLM flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £774 found 20 hours ago
Virgin Atlantic
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£784 Return, found 20 hours ago
£784
Return
found 20 hours ago
Select Virgin Atlantic flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £784 found 20 hours ago
Aer Lingus
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£829 Return, found 20 hours ago
£829
Return
found 20 hours ago
Select Aer Lingus flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £829 found 20 hours ago
British Airways
Mon, 14 Sept - Mon, 21 Sept
SOU
Southampton
SAN
San Diego
£1,153 Return, found 20 hours ago
£1,153
Return
found 20 hours ago
Select British Airways flight, departing Mon, 14 Sept from Southampton to San Diego, returning Mon, 21 Sept, priced at £1,153 found 20 hours ago

Frequently asked questions

How much does a flight from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) cost?
You can find one-way and return flights from SOU to SAN with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when SOU to SAN ticket fares go up or down.
What is the cheapest month to fly from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
The cheapest months to fly from SOU to SAN are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
Enter SOU to SAN and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
To find a cheap flight from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
There are approximately 5 connecting flights per day from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.). Some common connection points include Dublin Airport (DUB), Amsterdam Airport Schiphol (AMS), and Edinburgh Airport (EDI).
What is the earliest flight from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
The earliest flight from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) typically departs around 2:05 AM local time. This service is operated by Accessrail and Air Canada, and it's a seasonal service active in June. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
You'll typically find the most flights from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) on a Monday, with around 24 flights available. This gives you a good selection of options for your journey. Major airlines on this route include Accessrail, Aer Lingus, and Loganair.
What are the most popular departure times for flights from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
The most popular departure times for flights from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) are between 9am and 12pm. Many major carriers, including KLM, Aer Lingus and Accessrail, offer flights during this window. Many travellers prefer these morning flights as they allow for an early start to their journey, getting you to your destination sooner.
How long does it take to fly from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
There are no nonstop or one-stop flights from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.). Flights with two or more stops typically take around 22 hours 30 minutes. This journey covers a distance of approximately 8,797 kilometers. Keep in mind that actual flight times can vary due to factors like layover duration, routing, and weather conditions.
Can you fly business or first class from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
You can fly business class between SOU and SAN. You can fly business class with KLM.
How do I earn miles on a Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) flight with Expedia?
It's easy to earn miles on a Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Diego, CA (SAN) from Southampton (SOU)?
If you're planning to travel to San Diego from SOU, you can fly directly into San Diego Intl. (SAN) which offers international flights and connections. Some flights may connect through major hubs like Dublin (DUB), Schiphol (AMS), George Best Belfast City (BHD) before reaching San Diego. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) at the last minute?
Typically, booking a last minute flight from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package?
Securing a Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.)?
If you booked your Southampton (SOU) to San Diego, CA (SAN-San Diego Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Southampton
Destination airport
San Diego Intl.
Airlines serving
Aer Lingus, British Airways, KLM, Virgin Atlantic
Return price
£713
Distance
8744 km

Book with confidence

Compare flights from Southampton to San Diego easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Southampton to San Diego. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Diego Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Southampton to San Diego Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Southampton (SOU) to San Diego Intl. (SAN)

The easiest way to view the best deals on flights from Southampton to San Diego today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Southampton to San Diego Intl. start at just £713 and range up to £1,153.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Southampton and San Diego
  • booking your flight during September, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Southampton to San Diego flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Southampton to San Diego Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Southampton to San Diego easily and book with confidence

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*Available to Expedia members.