£142 Cheap Flights from Southampton (SOU) to Lyon (LYS)

View £142 flight on Thu, 28 May 2026Opens in a new window

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Popular airlines from Southampton (SOU) to Saint-Exupery Airport (LYS)

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Cheap Flights from Southampton (SOU) to Lyon (LYS)

Prices were available within the past 7 days and start at £142 for one-way flights and £219 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

KLM
Mon, 8 Jun - Fri, 12 Jun
SOU
Southampton
LYS
Lyon
£219 Return, found 13 hours ago
£219
Return
found 13 hours ago
Select KLM flight, departing Mon, 8 Jun from Southampton to Lyon, returning Fri, 12 Jun, priced at £219 found 13 hours ago
KLM
Fri, 25 Sept - Sun, 27 Sept
SOU
Southampton
LYS
Lyon
£223 Return, found 6 days ago
£223
Return
found 6 days ago
Select KLM flight, departing Fri, 25 Sept from Southampton to Lyon, returning Sun, 27 Sept, priced at £223 found 6 days ago
KLM
Fri, 25 Sept - Sun, 27 Sept
SOU
Southampton
LYS
Lyon
£224 Return, found 6 days ago
£224
Return
found 6 days ago
Select KLM flight, departing Fri, 25 Sept from Southampton to Lyon, returning Sun, 27 Sept, priced at £224 found 6 days ago
KLM
Wed, 6 May - Tue, 12 May
SOU
Southampton
LYS
Lyon
£227 Return, found 5 days ago
£227
Return
found 5 days ago
Select KLM flight, departing Wed, 6 May from Southampton to Lyon, returning Tue, 12 May, priced at £227 found 5 days ago
KLM
Thu, 4 Jun - Wed, 10 Jun
SOU
Southampton
LYS
Lyon
£231 Return, found 3 days ago
£231
Return
found 3 days ago
Select KLM flight, departing Thu, 4 Jun from Southampton to Lyon, returning Wed, 10 Jun, priced at £231 found 3 days ago
KLM
Mon, 8 Jun - Wed, 17 Jun
SOU
Southampton
LYS
Lyon
£232 Return, found 6 days ago
£232
Return
found 6 days ago
Select KLM flight, departing Mon, 8 Jun from Southampton to Lyon, returning Wed, 17 Jun, priced at £232 found 6 days ago
KLM
Sun, 7 Jun - Fri, 12 Jun
SOU
Southampton
LYS
Lyon
£233 Return, found 13 hours ago
£233
Return
found 13 hours ago
Select KLM flight, departing Sun, 7 Jun from Southampton to Lyon, returning Fri, 12 Jun, priced at £233 found 13 hours ago
KLM
Wed, 6 May - Tue, 12 May
SOU
Southampton
LYS
Lyon
£236 Return, found 5 days ago
£236
Return
found 5 days ago
Select KLM flight, departing Wed, 6 May from Southampton to Lyon, returning Tue, 12 May, priced at £236 found 5 days ago
Aer Lingus
Mon, 18 May - Wed, 20 May
SOU
Southampton
LYS
Lyon
£354 Return, found 3 days ago
£354
Return
found 3 days ago
Select Aer Lingus flight, departing Mon, 18 May from Southampton to Lyon, returning Wed, 20 May, priced at £354 found 3 days ago
British Airways
Thu, 17 Sept - Wed, 23 Sept
SOU
Southampton
LYS
Lyon
£501 Return, found 4 days ago
£501
Return
found 4 days ago
Select British Airways flight, departing Thu, 17 Sept from Southampton to Lyon, returning Wed, 23 Sept, priced at £501 found 4 days ago

Frequently asked questions

How much does a flight from Southampton (SOU) to Lyon (LYS-Saint-Exupery) cost?
One-way flights typically cost between £350 and £1,289 and return flights often range between £350 and £1,289. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.
How do I find cheap flights from Southampton (SOU) to Lyon (LYS-Saint-Exupery)?
To find a cheap flight from Southampton (SOU) to Lyon (LYS-Saint-Exupery), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Southampton (SOU) to Lyon (LYS-Saint-Exupery)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Southampton (SOU) to Lyon (LYS-Saint-Exupery)?
There are approximately 5 connecting flights per day from Southampton (SOU) to Lyon (LYS-Saint-Exupery). Some common connection points include Schiphol (AMS), Unknown (DUB), and Unknown (MAN).
What is the earliest flight from Southampton (SOU) to Lyon (LYS-Saint-Exupery)?
The earliest flight from Southampton (SOU) to Lyon (LYS-Saint-Exupery) typically departs at approximately 8:40 AM local time, operated by KLM and Air France. This is a seasonal service active in December. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Southampton (SOU) to Lyon (LYS-Saint-Exupery)?
If you're flying from Southampton (SOU) to Lyon (LYS-Saint-Exupery), you'll typically find the most flights on a Tuesday, with around 6 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Aer Lingus, KLM, and Loganair. Flight schedules are consistent throughout the week, so you'll have similar options on other days.
What are the most popular departure times for flights from Southampton (SOU) to Lyon (LYS-Saint-Exupery)?
The most popular departure times for flights from Southampton (SOU) to Lyon (LYS-Saint-Exupery) are in the morning, from 9am to 12pm. About 55% of passengers prefer this time. Many major carriers, including KLM and Air France, offer flights during this window. This timing works well because it allows you to start your travel day at a reasonable hour and arrive in Lyon with plenty of time to settle in.
How long does it take to fly from Southampton (SOU) to Lyon (LYS-Saint-Exupery)?
Flying from SOU to LYS with a connection usually takes about 23 hours 20 minutes, traveling roughly 467 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Southampton (SOU) to Lyon (LYS-Saint-Exupery)?
Select the "Business class" and "First class" filters when looking for SOU to LYS flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Southampton (SOU) to Lyon (LYS-Saint-Exupery) flight with Expedia?
It's easy to earn miles on a Southampton (SOU) to Lyon (LYS-Saint-Exupery) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Lyon from SOU (SOU)?
From SOU (SOU), you can fly directly into Saint Exupery (LYS) to reach Lyon. Some flights may connect through major hubs like Schiphol (AMS), EDI (EDI) before reaching Lyon. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Southampton (SOU) to Lyon (LYS-Saint-Exupery) at the last minute?
Typically, booking a last minute flight from Southampton (SOU) to Lyon (LYS-Saint-Exupery) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Southampton (SOU) to Lyon (LYS-Saint-Exupery) flight and hotel package?
Securing a Southampton (SOU) to Lyon (LYS-Saint-Exupery) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Southampton (SOU) to Lyon (LYS-Saint-Exupery)?
If you booked your Southampton (SOU) to Lyon (LYS-Saint-Exupery) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Southampton
Destination airport
Saint-Exupery
Airlines serving
Aer Lingus, British Airways, KLM
Return price
£218
Distance
746 km

Book with confidence

Compare flights from Southampton to Lyon easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Southampton to Lyon. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Saint-Exupery in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Southampton to Saint-Exupery.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Southampton (SOU) to Saint-Exupery (LYS)

The easiest way to view the best deals on flights from Southampton to Lyon today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Southampton to Saint-Exupery start at just £219 and range up to £501.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Southampton and Lyon
  • booking your flight during June, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Southampton to Lyon flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Southampton to Saint-Exupery for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Southampton to Lyon easily and book with confidence

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*Available to Expedia members.