£114 Cheap Flights from San Francisco (SFO) to Louisville (SDF)

View £114 flight on Mon, 18 May 2026Opens in a new window

Popular airlines from San Francisco International Airport (SFO) to Louisville International Airport (SDF)

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Cheap Flights from San Francisco (SFO) to Louisville (SDF)

Prices were available within the past 7 days and start at £114 for one-way flights and £291 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Breeze Airways
Fri, 2 Oct - Mon, 5 Oct
SFO
San Francisco
SDF
Louisville
£291 Return, found 2 days ago
£291
Return
found 2 days ago
Select Breeze Airways flight, departing Fri, 2 Oct from San Francisco to Louisville, returning Mon, 5 Oct, priced at £291 found 2 days ago
Breeze Airways
Fri, 2 Oct - Mon, 5 Oct
SFO
San Francisco
SDF
Louisville
£331 Return, found 2 days ago
£331
Return
found 2 days ago
Select Breeze Airways flight, departing Fri, 2 Oct from San Francisco to Louisville, returning Mon, 5 Oct, priced at £331 found 2 days ago
Breeze Airways
Fri, 2 Oct - Mon, 5 Oct
SFO
San Francisco
SDF
Louisville
£374 Return, found 2 days ago
£374
Return
found 2 days ago
Select Breeze Airways flight, departing Fri, 2 Oct from San Francisco to Louisville, returning Mon, 5 Oct, priced at £374 found 2 days ago
Alaska Airlines
Fri, 2 Oct - Mon, 5 Oct
SFO
San Francisco
SDF
Louisville
£423 Return, found 2 days ago
£423
Return
found 2 days ago
Select Alaska Airlines flight, departing Fri, 2 Oct from San Francisco to Louisville, returning Mon, 5 Oct, priced at £423 found 2 days ago
Alaska Airlines
Fri, 2 Oct - Mon, 5 Oct
SFO
San Francisco
SDF
Louisville
£462 Return, found 2 days ago
£462
Return
found 2 days ago
Select Alaska Airlines flight, departing Fri, 2 Oct from San Francisco to Louisville, returning Mon, 5 Oct, priced at £462 found 2 days ago
Alaska Airlines
Fri, 2 Oct - Mon, 5 Oct
SFO
San Francisco
SDF
Louisville
£505 Return, found 2 days ago
£505
Return
found 2 days ago
Select Alaska Airlines flight, departing Fri, 2 Oct from San Francisco to Louisville, returning Mon, 5 Oct, priced at £505 found 2 days ago

Frequently asked questions

What is the cheapest month to fly from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
August is typically the cheapest month to fly from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.), with average return fares of approximately £290. This is about 18% lower than the average price throughout the year. August often sees lower prices as it's outside the peak summer travel season for many destinations, leading to reduced demand. Other cheap months to fly from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) include May and September.
Which airlines fly direct from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
Enter SFO to SDF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
To find a cheap flight from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
The best airline to fly with from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) will differ from traveller to traveller. If you like to fly early, MX offers early morning flights. If price is the most important factor, MX typically offers the lowest fares. UA offers the most daily flights from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.), which is brilliant if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
The best time to fly from San Francisco, CA (SFO-San Francisco Intl.) (SFO) to Louisville, KY (SDF-Louisville Intl.) (SDF) for good value is typically August or September. Based on booking data from the past year, you can expect average return flight prices around £290 during these months. While we don't have specific popularity data for these months, flying during these times often means you can find good deals after the peak summer travel season.
How many flights per day from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
There are approximately 85 connecting flights per day from San Francisco International (SFO) to Louisville International (SDF). Some common connection points include O'Hare International (ORD), Dallas-Fort Worth International (DFW), and Los Angeles International (LAX).
What is the earliest flight from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
The earliest flight from San Francisco International Airport (SFO) to Louisville International Airport (SDF) typically departs at approximately 12:05 AM local time, operated by Delta. This is a seasonal service active in May. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
You'll typically find the most flights from San Francisco International Airport (SFO) to Louisville International Airport (SDF) on a Friday, with around 58 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include United Airlines, American Airlines, and Delta Air Lines. Flight schedules are fairly consistent throughout the week, with Fridays offering only slightly more options than other days.
What are the most popular departure times for flights from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
The most popular departure times for flights from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) are in the early morning, from 6am to 9am. About 26% of passengers prefer this time. Many major carriers, including American Airlines, United Airlines and Delta Air Lines, offer flights during this window. This timing works well because it allows you to get an early start on your travel day and arrive at your destination with plenty of time.
How long does it take to fly from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
A nonstop flight from SFO to SDF typically takes around 4 hours 30 minutes, covering approximately 1,985 miles. Connecting flights on this route usually add 3 hours 50 minutes to your travel time. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
Select the "Business class" and "First class" filters when looking for SFO to SDF flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) flight with Expedia?
It's easy to earn miles on a San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Louisville from San Francisco Intl. (SFO)?
If you're planning to travel to Louisville from San Francisco Intl. (SFO), you can fly directly into Louisville Intl. (SDF) Some flights may connect through major hubs like Sky Harbor Intl. (PHX), San Diego Intl. (SAN), Los Angeles Intl. (LAX) before reaching Louisville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) at the last minute?
Typically, booking a last minute flight from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) flight and hotel package?
Securing a San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.)?
If you booked your San Francisco, CA (SFO-San Francisco Intl.) to Louisville, KY (SDF-Louisville Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
San Francisco Intl.
Destination airport
Louisville Intl.
Return price
£291
Distance
3176 km
Average flight time
8 hours 30 mins

Book with confidence

Compare flights from San Francisco to Louisville easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from San Francisco to Louisville. Operating between them flights per day, 15 airlines cover the route. And fly direct, getting you to Louisville Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from San Francisco Intl. to Louisville Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from San Francisco Intl. (SFO) to Louisville Intl. (SDF)

The easiest way to view the best deals on flights from San Francisco to Louisville today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from San Francisco Intl. to Louisville Intl. start at just £291 and range up to £1,093.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near San Francisco and Louisville
  • booking your flight during October, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your San Francisco to Louisville flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from San Francisco Intl. to Louisville Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from San Francisco to Louisville easily and book with confidence

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*Available to Expedia members.