£250 Cheap Flights from San Diego (SAN) to Louisville (SDF)

View £250 flight on Fri, 19 Jun 2026Opens in a new window

Popular airlines from San Diego Intl. Airport (SAN) to Louisville International Airport (SDF)

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Cheap Flights from San Diego (SAN) to Louisville (SDF)

Prices were available within the past 7 days and start at £250 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much is a flight from SAN to Louisville Intl. Airport (SDF)?
If you're travelling between San Diego Airport and Louisville Muhammad Ali Intl. Airport, round-trip journeys start from . This figure is based on airfares available within the last 7 days on Expedia for flights departing within the next year, so don't hang about. Book today and save yourself money and time. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from San Diego Airport to Louisville Muhammad Ali Intl. Airport?
Most flights can be cancelled online, but whether you are charged a fee differs between airlines. If you do need to cancel your getaway, follow the instructions in the Customer Service Portal.
How do I find cheap flights from San Diego Intl. Airport (SAN) to Louisville Muhammad Ali Intl. Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for San Diego Intl. Airport (SAN) to Louisville Muhammad Ali Intl. Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from SAN to SDF?
Expect to be soaring through the sky for a while, as the flight distance between SAN and Louisville Muhammad Ali Intl. Airport is 2,900 kilometres. Set up a playlist of your favourite podcasts before leaving home to keep yourself entertained during your journey.
Which airlines fly direct from San Diego Intl. Airport (SAN) to SDF?
Unfortunately, there are no airlines that directly fly between San Diego Intl. Airport (SAN) and Louisville Muhammad Ali Intl. Airport. You'll have to book a flight with at least one stop.
Are San Diego Airport to Louisville Intl. Airport (SDF) flight tickets cheaper when they're purchased at the last minute?
Booking last minute from San Diego Intl. Airport (SAN) to Louisville Intl. Airport (SDF) can be hit-or-miss. It is possible to score a bargain, but you could also miss out completely! If you'd rather play it safe and start your trip planning early, Expedia compares flight deals up to 12 months in advance. Just remember that not all airlines list their prices that far in advance. Our suggestion? Check back often as updates are made regularly.

Frequently asked questions

How do I find cheap flights from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.)?
To find a cheap flight from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.)?
There are approximately 83 connecting flights per day from San Diego International (SAN) to Louisville International (SDF). Some common connection points include Seattle - Tacoma International Airport (SEA), O'Hare International Airport (ORD), and Dallas-Fort Worth International Airport (DFW).
What is the earliest flight from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.)?
The earliest flight from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.) typically departs at approximately 12:55 AM local time. This flight is operated by American Airlines and is a seasonal service active in September. An early departure like this can help you maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.)?
You'll typically find the most flights from San Diego Intl. (SAN) to Louisville Intl. (SDF) on a Friday, with around 75 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Southwest Airlines, United Airlines, and American Airlines. Friday offers notably more flight options compared to other days of the week.
What are the most popular departure times for flights from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.)?
The most popular departure times for flights from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.) are in the early morning, from 6am to 9am. About 39% of passengers prefer this time. Many major carriers, including American Airlines, Southwest Airlines and Delta Air Lines, offer flights during this window. This timing works well because it allows you to get an early start on your travel day and arrive at your destination with plenty of time.
How long does it take to fly from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.)?
Flying from SAN to SDF with a connection usually takes about 6 hours 50 minutes, traveling roughly 1,801 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.)?
Select the "Business class" and "First class" filters when looking for SAN to SDF flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.) flight with Expedia?
It's easy to earn miles on a San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Louisville from San Diego Intl. (SAN)?
From San Diego Intl. (SAN), you can fly directly into Louisville Intl. (SDF) to reach Louisville. Some flights may connect through major hubs like Sky Harbor Intl. (PHX), Seattle - Tacoma Intl. (SEA), McCarran Intl. (LAS) before reaching Louisville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.) at the last minute?
Typically, booking a last minute flight from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.) flight and hotel package?
Securing a San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.)?
If you booked your San Diego, CA (SAN-San Diego Intl.) to Louisville, KY (SDF-Louisville Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
San Diego Intl.
Destination airport
Louisville Intl.
Distance
2881 km

Book with confidence

Compare flights from San Diego to Louisville easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from San Diego to Louisville. Operating between them flights per day, 3 airlines cover the route. And fly direct, getting you to Louisville Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from San Diego Intl. to Louisville Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from San Diego Intl. (SAN) to Louisville Intl. (SDF)

The easiest way to view the best deals on flights from San Diego to Louisville today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from San Diego Intl. to Louisville Intl. start at just and range up to .  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near San Diego and Louisville
  • booking your flight during , the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your San Diego to Louisville flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from San Diego Intl. to Louisville Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from San Diego to Louisville easily and book with confidence

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