Title: Cheap Flights from Santander to Mytilene (SDR to MJT) - Expedia.co.uk ![Adobe](https://images.trvl-media.com/place/181073/34d2c68c-fc88-4580-9861-a78e52c104ff.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/181073/34d2c68c-fc88-4580-9861-a78e52c104ff.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from Santander (SDR) to Mytilene (MJT) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Santander (SDR) to Mytilene (MJT-Mytilene Intl.) - ![British Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_BA.svg) British Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:sdr,to:mjt,departure:02/10/2025TANYT&leg2=from:mjt,to:sdr,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"BA"}}]) - ![easyJet](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_U2.svg) easyJet [](https://www.expedia.co.uk/Flights-Search?leg1=from:sdr,to:mjt,departure:02/10/2025TANYT&leg2=from:mjt,to:sdr,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"U2"}}]) - ![Lufthansa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LH.svg) Lufthansa [](https://www.expedia.co.uk/Flights-Search?leg1=from:sdr,to:mjt,departure:02/10/2025TANYT&leg2=from:mjt,to:sdr,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LH"}}]) - ![Ryanair](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_FR.svg) Ryanair [](https://www.expedia.co.uk/Flights-Search?leg1=from:sdr,to:mjt,departure:02/10/2025TANYT&leg2=from:mjt,to:sdr,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"FR"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sdr,to:mjt,departure:02/10/2025TANYT&leg2=from:mjt,to:sdr,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Jet2](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LS.svg) Jet2 [](https://www.expedia.co.uk/Flights-Search?leg1=from:sdr,to:mjt,departure:02/10/2025TANYT&leg2=from:mjt,to:sdr,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LS"}}]) - ![Swiss International Air Lines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LX.svg) Swiss International Air Lines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sdr,to:mjt,departure:02/10/2025TANYT&leg2=from:mjt,to:sdr,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LX"}}]) - ## Plan, book, fly with confidence - ### Be in the know Get alerts if flight prices drop or rise\* - ### Book smarter Save up to 25% on select hotels after you book a flight\* - ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) Flight from Santander to Mytilene route information | Origin airport | Santander | | --- | --- | | Destination airport | Mytilene Intl. | | Distance | 2560 km | ## Compare flights from Santander to Mytilene easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Santander to Mytilene. Operating between them flights per day, airlines cover the route. And fly direct, getting you to Mytilene Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Santander to Mytilene Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Santander (SDR) to Mytilene Intl. (MJT) The easiest way to view the best deals on flights from Santander to Mytilene today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Santander to Mytilene Intl. start at just and range up to .   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Santander and Mytilene - booking your flight during , the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Santander to Mytilene flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Santander to Mytilene Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other ### Accommodation - [4 Star Hotels in Lesvos](https://www.expedia.co.uk/4Star-Lesvos-Hotels.s40-0-d181073.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Lesvos](https://www.expedia.co.uk/5Star-Lesvos-Hotels.s50-0-d181073.Travel-Guide-Filter-Hotels) - [Agia Marina Lesvos Hotels](https://www.expedia.co.uk/Agia-Marina-Lesvos-Hotels.d553248635975865297.Travel-Guide-Hotels) - [Ano Chalikas Hotels](https://www.expedia.co.uk/Ano-Chalikas-Hotels.d3000739625.Travel-Guide-Hotels) - [Charamida Hotels](https://www.expedia.co.uk/Charamida-Hotels.d3000031310.Travel-Guide-Hotels) - [All-Inclusive Hotels in North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands-All-Inclusive-Hotel.0-0-d6051354-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Casino Hotels in North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands-Casino-Hotel.0-0-d6051354-tCasinoHotel.Hotel-Filter-Destinations) - [Family-Friendly Hotels in North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands-Family-Friendly-Hotel.0-0-d6051354-tFamilyFriendlyHotel.Hotel-Filter-Destinations) - [Hotels with a View in North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands-Hotel-With-A-View.0-0-d6051354-thotelwithaview.Hotel-Filter-Destinations) - [Hotels with Entertainment in North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands-Hotel-With-Entertainment.0-0-d6051354-thotelwithentertainment.Hotel-Filter-Destinations) - [Hotels with Hot Tubs in North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands-Hotels-With-Hot-Tubs.0-0-d6051354-tHotelsWithHotTubs.Hotel-Filter-Destinations) - [Luxury Hotels in North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands-Luxury-Hotel.0-0-d6051354-tLuxuryHotel.Hotel-Filter-Destinations) - [Shopping Hotels in North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands-Shopping-Hotel.0-0-d6051354-tshoppinghotel.Hotel-Filter-Destinations) - [Yoga Hotels in North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands-Yoga-Hotels.0-0-d6051354-tYogaHotels.Hotel-Filter-Destinations) - [North Aegean Islands Hotels](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands.d6051354.Hotel-Destinations) - [Gera Hotels](https://www.expedia.co.uk/Gera-Hotels.d6143092.Travel-Guide-Hotels) - [Farmstay in Lesvos](https://www.expedia.co.uk/Lesvos-Agritourism.d181073-aaAgritourism.Travel-Guide-Accommodation) - [Serviced Apartments in Lesvos](https://www.expedia.co.uk/Lesvos-Apart-Hotels.d181073-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Lesvos](https://www.expedia.co.uk/Lesvos-Bed-And-Breakfasts.d181073-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Resorts in Lesvos](https://www.expedia.co.uk/Lesvos-Hotel-Resorts.d181073-aaHotelResorts.Travel-Guide-Accommodation) - [Adults Only Resorts & in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Adults-Only-Resorts.0-0-d181073-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Sports Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Adventure-Sport-Hotel.0-0-d181073-tAdventureSportHotel.Travel-Guide-Filter-Hotels) - [All-Inclusive Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-All-Inclusive-Hotel.0-0-d181073-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Beach-Hotels.0-0-d181073-tBeachHotels.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Budget-Hotels.0-0-d181073-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Casino Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Casino-Hotel.0-0-d181073-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Family-Friendly-Hotel.0-0-d181073-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Gay-Friendly-Hotel.0-0-d181073-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Golf Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Golf-Hotels.0-0-d181073-tGolfHotels.Travel-Guide-Filter-Hotels) - [Hotels with Airport Transfers in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Hotel-With-Airport-Transfers.0-0-d181073-thotelwithairporttransfers.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Hotels-With-Hot-Tubs.0-0-d181073-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Hotels-With-Indoor-Pools.0-0-d181073-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Hotels-With-Smoking-Rooms.0-0-d181073-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Hotels with Waterslides in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Hotels-With-Waterslides.0-0-d181073-tHotelswithWaterslides.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Luxury-Hotel.0-0-d181073-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Mountain-Hotel.0-0-d181073-tmountainhotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Pet-Friendly-Hotel.0-0-d181073-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Spa-Hotels.0-0-d181073-tSpaHotels.Travel-Guide-Filter-Hotels) - [Hotels with Waterpark in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Waterpark-Hotel.0-0-d181073-twaterparkhotel.Travel-Guide-Filter-Hotels) - [Wedding Hotels in Lesvos](https://www.expedia.co.uk/Lesvos-Hotels-Wedding-Hotel.0-0-d181073-tWeddingHotel.Travel-Guide-Filter-Hotels) - [Lesvos Hotels](https://www.expedia.co.uk/Lesvos-Hotels.d181073.Travel-Guide-Hotels) - [Villas in Lesvos](https://www.expedia.co.uk/Lesvos-Villas.d181073-aaVillas.Travel-Guide-Accommodation) - [Loutra Hotels](https://www.expedia.co.uk/Loutra-Hotels.d553248635975855987.Travel-Guide-Hotels) - [Hotels near Monastery of Saint Raphael](https://www.expedia.co.uk/Monastery-Of-Saint-Raphael-Hotels.0-l6330180-0.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Mytilene](https://www.expedia.co.uk/Mytilene-Hotels-Beach-Hotels.0-0-d6062865-tBeachHotels.Travel-Guide-Filter-Hotels) - [Mytilene Hotels](https://www.expedia.co.uk/Mytilene-Hotels.d6062865.Travel-Guide-Hotels) - [Neapoli Hotels](https://www.expedia.co.uk/Neapoli-Hotels.d6321829.Travel-Guide-Hotels) - [Caravan Parks in North Aegean Islands](https://www.expedia.co.uk/North-Aegean-Islands-Caravan-Parks.d6051354-aaCaravanParks.Travel-Guide-Accommodation) - [Panagiouda Hotels](https://www.expedia.co.uk/Panagiouda-Hotels.d3000739637.Travel-Guide-Hotels) - [Perama Hotels](https://www.expedia.co.uk/Perama-Hotels.d6135648.Travel-Guide-Hotels) - [Pirgi Hotels](https://www.expedia.co.uk/Pirgi-Hotels.d553248635975855498.Travel-Guide-Hotels) - [Pirgi Thermis Hotels](https://www.expedia.co.uk/Pirgi-Thermis-Hotels.d6322116.Travel-Guide-Hotels) - [Hotels near Roman Aqueduct at Moria](https://www.expedia.co.uk/Roman-Aqueduct-At-Moria-Hotels.0-l6330367-0.Travel-Guide-Filter-Hotels) - [Skala Loutron Hotels](https://www.expedia.co.uk/Skala-Loutron-Hotels.d6322118.Travel-Guide-Hotels) - [Tarti Hotels](https://www.expedia.co.uk/Tarti-Hotels.d3000030171.Travel-Guide-Hotels) - [Varia Hotels](https://www.expedia.co.uk/Varia-Hotels.d6322122.Travel-Guide-Hotels) ### Flights - [Flights to Apidias Lakkos](https://www.expedia.co.uk/Cheap-Flights-To-Apidias-Lakkos.d6321826.Travel-Guide-Flights) - [Flights to Gera](https://www.expedia.co.uk/Cheap-Flights-To-Gera.d6143092.Travel-Guide-Flights) - [Flights to Lesvos](https://www.expedia.co.uk/Cheap-Flights-To-Lesvos.d181073.Travel-Guide-Flights) - [Flights to Mytilene](https://www.expedia.co.uk/Cheap-Flights-To-Mytilene.d6062865.Travel-Guide-Flights) - [Flights to Perama](https://www.expedia.co.uk/Cheap-Flights-To-Perama.d6135648.Travel-Guide-Flights) - [Flights to Pirgi Thermis](https://www.expedia.co.uk/Cheap-Flights-To-Pirgi-Thermis.d6322116.Travel-Guide-Flights) - [Flights to North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands.d6051354.Flight-Destinations) - [Flights from Lesvos](https://www.expedia.co.uk/lp/flights/181073/flights-from-lesvos) - [Flights from Mytilene](https://www.expedia.co.uk/lp/flights/6062865/flights-from-mytilene) - [Flights from Skala Loutron](https://www.expedia.co.uk/lp/flights/6322118/flights-from-skala-loutron) ### Packages - [Church of Agios Therapon](https://www.expedia.co.uk/Church-Of-Agios-Therapon-Lesvos.d553248621533101623.Attraction) - [Lesvos Holidays](https://www.expedia.co.uk/Lesvos.d181073.Holidays-City-Breaks) - [Visit Lesvos](https://www.expedia.co.uk/Lesvos.dx181073) - [Visit Loutropoli Thermis](https://www.expedia.co.uk/Loutropoli-Thermis.dx6321827) - [Monastery of Saint Raphael](https://www.expedia.co.uk/Monastery-Of-Saint-Raphael-Lesvos.d6330180.Attraction) - [Mytilene Holidays](https://www.expedia.co.uk/Mytilene.d6062865.Holidays-City-Breaks) - [North Aegean Islands Holidays](https://www.expedia.co.uk/North-Aegean-Islands.d6051354.Holidays-City-Breaks) - [Visit North Aegean Islands](https://www.expedia.co.uk/North-Aegean-Islands.dx6051354) - [Visit Perama](https://www.expedia.co.uk/Perama.dx6135648) - [Roman Aqueduct at Moria](https://www.expedia.co.uk/Roman-Aqueduct-At-Moria-Lesvos.d6330367.Attraction) - [Visit Tarti](https://www.expedia.co.uk/Tarti.dx3000030171) - [Teriade Museum](https://www.expedia.co.uk/Teriade-Museum-Lesvos.d6192465.Attraction) - [Thermi Beach](https://www.expedia.co.uk/Thermi-Beach-North-Aegean-Islands.d6330466.Attraction) - [Visit Varia](https://www.expedia.co.uk/Varia.dx6322122) ### Cars - [Alamo Rent A Car Rental Cars in Lesvos](https://www.expedia.co.uk/Alamo-Rent-A-Car-Car-Rentals-In-Lesvos.d181073-c6.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Lesvos](https://www.expedia.co.uk/Avis-Car-Rentals-In-Lesvos.d181073-c41.Car-Rental-Guide-Suppliers) - [Budget Canaries Rental Cars in North Aegean Islands](https://www.expedia.co.uk/Budget-Canaries-Destinations-In-North-Aegean-Islands.d6051354-c1136.Car-Rental-Destination-Suppliers) - [Budget Rental Cars in Lesvos](https://www.expedia.co.uk/Budget-Car-Rentals-In-Lesvos.d181073-c39.Car-Rental-Guide-Suppliers) - [Car hire Lesvos](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Lesvos.d181073.Car-Hire-Guide) - [Car hire Mytilene](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Mytilene.d6062865.Car-Hire-Guide) - [Convertible Car Hire in Lesvos](https://www.expedia.co.uk/Convertible-Car-Rentals-In-Lesvos.d181073-tConvertible.Car-Rental-Guide-Class) - [Car hire near North Aegean Islands](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands.d6051354.Car-Hire-Destinations) - [Economy Car Hire in Lesvos](https://www.expedia.co.uk/Economy-Car-Rentals-In-Lesvos.d181073-tEconomy.Car-Rental-Guide-Class) - [Europcar Rental Cars in Lesvos](https://www.expedia.co.uk/Europcar-Car-Rentals-In-Lesvos.d181073-c14.Car-Rental-Guide-Suppliers) - [Goldcar rental Rental Cars in North Aegean Islands](https://www.expedia.co.uk/Goldcar-Rental-Destinations-In-North-Aegean-Islands.d6051354-c1022.Car-Rental-Destination-Suppliers) - [Guerin Rental Cars in Lesvos](https://www.expedia.co.uk/Guerin-Car-Rentals-In-Lesvos.d181073-c1129.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Lesvos](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Lesvos.d181073-c40.Car-Rental-Guide-Suppliers) - [Luxury Car Hire in Lesvos](https://www.expedia.co.uk/Luxury-Car-Rentals-In-Lesvos.d181073-tLuxury.Car-Rental-Guide-Class) - [Pickup Car Hire in Lesvos](https://www.expedia.co.uk/Pickup-Car-Rentals-In-Lesvos.d181073-tPickup.Car-Rental-Guide-Class) - [Thrifty NZ Rental Cars in North Aegean Islands](https://www.expedia.co.uk/Thrifty-NZ-Destinations-In-North-Aegean-Islands.d6051354-c1119.Car-Rental-Destination-Suppliers) ### Holiday Homes - [North Aegean Islands Holiday Rentals](https://www.expedia.co.uk/Destinations-In-North-Aegean-Islands.d6051354.Holiday-Rental-Destinations) - [Lesvos Holiday Rentals](https://www.expedia.co.uk/Lesvos-Holiday-Rentals.d181073.Travel-Guide-HolidayRentals) - [Mytilene Holiday Rentals](https://www.expedia.co.uk/Mytilene-Holiday-Rentals.d6062865.Travel-Guide-HolidayRentals) ### Other - [Things to do in North Aegean Islands](https://www.expedia.co.uk/Things-To-Do-In-North-Aegean-Islands.d6051354.Travel-Guide-Activities) \*Available to Expedia members.