£81 Cheap Flights from Rome (ROM) to Istanbul (IST)

View £81 flight on Wed, 10 Dec 2025Opens in a new window

Popular airlines from Rome to Istanbul (IST)

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Cheap Flights from Rome (ROM) to Istanbul (IST)

Prices were available within the past 7 days and start at £81 for one-way flights and £186 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Serbia
Thu, 23 Oct - Mon, 27 Oct
FCO
Rome
IST
Istanbul
£186 Return, found 3 days ago
£186
Return
found 3 days ago
Select Air Serbia flight, departing Thu, 23 Oct from Rome to Istanbul, returning Mon, 27 Oct, priced at £186 found 3 days ago
Lufthansa
Wed, 26 Nov - Wed, 17 Dec
FCO
Rome
IST
Istanbul
£196 Return, found 19 hours ago
£196
Return
found 19 hours ago
Select Lufthansa flight, departing Wed, 26 Nov from Rome to Istanbul, returning Wed, 17 Dec, priced at £196 found 19 hours ago
Air Serbia
Sun, 9 Nov - Sat, 22 Nov
FCO
Rome
IST
Istanbul
£208 Return, found 3 days ago
£208
Return
found 3 days ago
Select Air Serbia flight, departing Sun, 9 Nov from Rome to Istanbul, returning Sat, 22 Nov, priced at £208 found 3 days ago
Vueling Airlines
Wed, 12 Nov - Sat, 15 Nov
FCO
Rome
IST
Istanbul
£212 Return, found 4 days ago
£212
Return
found 4 days ago
Select Vueling Airlines flight, departing Wed, 12 Nov from Rome to Istanbul, returning Sat, 15 Nov, priced at £212 found 4 days ago
Aegean
Thu, 11 Dec - Sun, 14 Dec
FCO
Rome
IST
Istanbul
£214 Return, found 5 days ago
£214
Return
found 5 days ago
Select Aegean flight, departing Thu, 11 Dec from Rome to Istanbul, returning Sun, 14 Dec, priced at £214 found 5 days ago
LOT-Polish Airlines
Fri, 12 Dec - Tue, 16 Dec
FCO
Rome
IST
Istanbul
£222 Return, found 5 days ago
£222
Return
found 5 days ago
Select LOT-Polish Airlines flight, departing Fri, 12 Dec from Rome to Istanbul, returning Tue, 16 Dec, priced at £222 found 5 days ago
KLM
Fri, 21 Nov - Tue, 25 Nov
FCO
Rome
IST
Istanbul
£224 Return, found 4 days ago
£224
Return
found 4 days ago
Select KLM flight, departing Fri, 21 Nov from Rome to Istanbul, returning Tue, 25 Nov, priced at £224 found 4 days ago
Air France
Sun, 9 Nov - Sat, 22 Nov
FCO
Rome
IST
Istanbul
£226 Return, found 3 days ago
£226
Return
found 3 days ago
Select Air France flight, departing Sun, 9 Nov from Rome to Istanbul, returning Sat, 22 Nov, priced at £226 found 3 days ago
Turkish Airlines
Wed, 26 Nov - Wed, 17 Dec
FCO
Rome
IST
Istanbul
£226 Return, found 19 hours ago
£226
Return
found 19 hours ago
Select Turkish Airlines flight, departing Wed, 26 Nov from Rome to Istanbul, returning Wed, 17 Dec, priced at £226 found 19 hours ago
KM Malta Airlines
Wed, 22 Oct - Tue, 28 Oct
FCO
Rome
IST
Istanbul
£254 Return, found 4 days ago
£254
Return
found 4 days ago
Select KM Malta Airlines flight, departing Wed, 22 Oct from Rome to Istanbul, returning Tue, 28 Oct, priced at £254 found 4 days ago

Find the cheapest month to fly from Rome (ROM) to Istanbul (IST)

December is typically the cheapest month to fly

From £81 - £227 per traveller.

Graph displaying average flight prices per month

Flight from Rome to Istanbul route information
Origin airport
Fiumicino - Leonardo da Vinci Intl.
Destination airport
Istanbul
Airlines serving
AJET, Aegean, Air Baltic, Air France, Air Serbia, British Airways, Croatia Airlines, ITA Airways, Iberia, KLM, KM Malta Airlines, LOT-Polish Airlines, Lufthansa, Pegasus Airlines, SKY express, Tarom-Romanian Air Transport, Turkish Airlines, Vueling Airlines
Return price
£186
Distance
1364 km

Compare flights from Rome to Istanbul easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Rome to Istanbul. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Istanbul in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from ROM-All Airports to Istanbul.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from ROM-All Airports (ROM) to Istanbul (IST)

The easiest way to view the best deals on flights from Rome to Istanbul today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from ROM-All Airports to Istanbul start at just £186 and range up to £254.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Rome and Istanbul
  • booking your flight during October, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Rome to Istanbul flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from ROM-All Airports to Istanbul for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

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