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£57 Cheap Flights from Lyon (LYS) to Brussels (BRU)

View £57 flight on Mon, 23 Nov 2026Opens in a new window

Flight 1

Popular airlines from Saint-Exupery Airport (LYS) to Brussels Airport (BRU)

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Cheap Flights from Lyon (LYS) to Brussels (BRU)

Prices were available within the past 7 days and start at £57 for one-way flights and £121 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Brussels Airlines
Thu, 12 Nov - Thu, 19 Nov
LYS
Lyon
BRU
Brussels
£121 Return, found 5 days ago
£121
Return
found 5 days ago
Select Brussels Airlines flight, departing Thu, 12 Nov from Lyon to Brussels, returning Thu, 19 Nov, priced at £121 found 5 days ago
Brussels Airlines
Wed, 30 Sept - Sat, 3 Oct
LYS
Lyon
BRU
Brussels
£136 Return, found 13 hours ago
£136
Return
found 13 hours ago
Select Brussels Airlines flight, departing Wed, 30 Sept from Lyon to Brussels, returning Sat, 3 Oct, priced at £136 found 13 hours ago
Brussels Airlines
Wed, 16 Sept - Wed, 23 Sept
LYS
Lyon
BRU
Brussels
£136 Return, found 6 days ago
£136
Return
found 6 days ago
Select Brussels Airlines flight, departing Wed, 16 Sept from Lyon to Brussels, returning Wed, 23 Sept, priced at £136 found 6 days ago
Brussels Airlines
Wed, 18 Nov - Wed, 25 Nov
LYS
Lyon
BRU
Brussels
£146 Return, found 5 days ago
£146
Return
found 5 days ago
Select Brussels Airlines flight, departing Wed, 18 Nov from Lyon to Brussels, returning Wed, 25 Nov, priced at £146 found 5 days ago
Brussels Airlines
Tue, 22 Sept - Tue, 29 Sept
LYS
Lyon
BRU
Brussels
£151 Return, found 3 days ago
£151
Return
found 3 days ago
Select Brussels Airlines flight, departing Tue, 22 Sept from Lyon to Brussels, returning Tue, 29 Sept, priced at £151 found 3 days ago
Brussels Airlines
Thu, 12 Nov - Thu, 19 Nov
LYS
Lyon
BRU
Brussels
£152 Return, found 5 days ago
£152
Return
found 5 days ago
Select Brussels Airlines flight, departing Thu, 12 Nov from Lyon to Brussels, returning Thu, 19 Nov, priced at £152 found 5 days ago
KLM
Thu, 12 Nov - Thu, 19 Nov
LYS
Lyon
BRU
Brussels
£155 Return, found 5 days ago
£155
Return
found 5 days ago
Select KLM flight, departing Thu, 12 Nov from Lyon to Brussels, returning Thu, 19 Nov, priced at £155 found 5 days ago
Vueling Airlines
Sun, 15 Nov - Sun, 22 Nov
LYS
Lyon
BRU
Brussels
£159 Return, found 5 days ago
£159
Return
found 5 days ago
Select Vueling Airlines flight, departing Sun, 15 Nov from Lyon to Brussels, returning Sun, 22 Nov, priced at £159 found 5 days ago
Lufthansa
Wed, 30 Sept - Sat, 3 Oct
LYS
Lyon
BRU
Brussels
£164 Return, found 13 hours ago
£164
Return
found 13 hours ago
Select Lufthansa flight, departing Wed, 30 Sept from Lyon to Brussels, returning Sat, 3 Oct, priced at £164 found 13 hours ago
Austrian Airlines
Thu, 12 Nov - Thu, 19 Nov
LYS
Lyon
BRU
Brussels
£176 Return, found 5 days ago
£176
Return
found 5 days ago
Select Austrian Airlines flight, departing Thu, 12 Nov from Lyon to Brussels, returning Thu, 19 Nov, priced at £176 found 5 days ago

Frequently asked questions

How much does a flight from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) cost?
You can find one-way and return flights from LYS to BRU with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when LYS to BRU ticket fares go up or down.
What is the cheapest month to fly from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
June is typically the cheapest month to fly from Lyon-Saint Exupery (LYS) to Brussels - National (BRU), with average return fares around £163. June often sees lower prices as it can be a shoulder season before the peak summer travel, or due to specific airline promotions. March and April are also good months to find deals on this route.
Which airlines fly direct from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
There are 2 airlines offering direct flights from Lyon Saint-Exupery (LYS) to Brussels (BRU). Here are the carriers:
  • Brussels Airlines operates 13 direct flights from Lyon Saint-Exupery (LYS) to Brussels (BRU) every week.
  • Etihad Airways operates 7 direct flights from Lyon Saint-Exupery (LYS) to Brussels (BRU) every week.
What is the cheapest airline that flies from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
Brussels Airlines is one of the cheapest airlines offering nonstop return flights from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National), with prices starting from around £97 for flights that can be booked for departure within the next year. Norwegian Air Shuttle offers one of the cheapest connecting return flights from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) starting from around £263. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
To find a cheap flight from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
The best airline to fly with from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) will differ from traveler to traveler. If you like to fly early, Brussels Airlines offers early morning flights. If price is the most important factor, Air Baltic typically offers the lowest fares. Lufthansa offers the most daily flights from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
The cheapest months to fly from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) are typically June and April, with average prices around £163. However, the most popular months for this route are November and October, which means you'll find plenty of flight options during those times. If you're looking for the best balance between price and availability, you might consider flying in April or June for better value, or in October or November if having more flight choices is your priority.
How many flights per day from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
You'll find approximately 2 nonstop flights per day from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National). For even more choices, look at flights that include layovers, as there are around 33 connecting flights per day. Some common connection points include Frankfurt Intl. (FRA), Roissy-Charles de Gaulle (CDG), and Franz Josef Strauss Intl. (MUC).
What is the earliest flight from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
The earliest flight from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) typically departs around 5:10 AM. This service is operated by Portugalia and Brussels Airlines. This is a seasonal service active in November and December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
You'll typically find the most flights from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) on a Thursday, with around 34 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Air France, Lufthansa, and KLM. Flight schedules are quite consistent throughout the week, so you'll have plenty of options no matter when you choose to fly.
What are the most popular departure times for flights from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
The most popular departure time for flights from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) is between 12pm and 3pm. Many major carriers, including Brussels Airlines, Air France and Lufthansa, offer flights during this window. Many travellers prefer this time as it allows for a relaxed morning before heading to the airport, and you'll arrive in Brussels with plenty of time to settle in or start your activities.
How long does it take to fly from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
A non-stop flight from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) typically takes around 1 hour 30 minutes, covering a distance of about 578 kilometres. If you opt for a one-stop flight, the journey usually takes longer, around 8 hours 18 minutes. Flights with two or more stops will extend your travel time even further, to about 12 hours. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some flexibility in your travel plans.
Can you fly business or first class from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
Yes, you can fly business class between LYS and BRU. Airlines that offer business class service on this route include:
  • Brussels Airlines
  • Malta Airlines
  • British Airways
  • Avianca Argentina
  • KLM
  • Lufthansa
  • Iberia
  • Air France
  • Air Dolomiti
  • Air Baltic
  • Lufthansa Cityline
  • Austrian Airlines
  • LOT-Polish Airlines
  • SAS
  • Hop!
  • Portugalia
  • Cityjet
How do I earn miles on a Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) flight with Expedia?
It's easy to earn miles on a Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Brussels (BRU) from Lyon (LYS)?
If you're planning to travel to Brussels from Saint Exupery (LYS), you can fly directly into Brussels - National (BRU). Some flights may connect through major hubs like Schiphol (AMS), Roissy-Charles de Gaulle (CDG), or Frankfurt Intl. (FRA) before reaching Brussels. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) at the last minute?
Typically, booking a last minute flight from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) flight and hotel package?
Securing a Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National)?
If you booked your Lyon (LYS-Saint-Exupery) to Brussels (BRU-Brussels - National) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Saint-Exupery
Destination airport
Brussels - National
Airlines serving
Aer Lingus, Austrian Airlines, British Airways, Brussels Airlines, Iberia, KLM, LOT-Polish Airlines, Lufthansa, Scandinavian Airlines, Vueling Airlines
Return price
£120
Distance
573 km
Average flight time
1 hour 25 mins

Book with confidence

Compare flights from Lyon to Brussels easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Lyon to Brussels. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Brussels - National in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Saint-Exupery to Brussels - National.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Saint-Exupery (LYS) to Brussels - National (BRU)

The easiest way to view the best deals on flights from Lyon to Brussels today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Saint-Exupery to Brussels - National start at just £121 and range up to £176.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Lyon and Brussels
  • booking your flight during November, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Lyon to Brussels flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Saint-Exupery to Brussels - National for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Lyon to Brussels easily and book with confidence

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