Title: £45 Cheap Flights from Porto to Brussels (OPO to BRU) - Expedia.co.uk ![](https://images.trvl-media.com/place/178241/ccd70fac-089f-4243-91b3-72fd772c4d15.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/178241/ccd70fac-089f-4243-91b3-72fd772c4d15.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £45 Cheap Flights from Porto (OPO) to Brussels (BRU) [View £45 flight on Wed, 21 Jan 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:OPO,to:BRU,departure:21/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:44.55&airProductToken=AQppCjII1rIBEgQ4NDc5GO5zIMFoKIOIgwMw54iDAzjEqgFAAFgBaghGTFlMSUdIVHIERENGQgozCNayARIEODk4MBjBaCChpAEo1IuDAzDbjIMDOMSqAUAAWAFqCEZMWUxJR0hUcgREQ0ZCEgoICxABGAgqAlZZGAEiBAgBEAEoAjAD) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Porto Airport (OPO) to Brussels - ![TAP Portugal](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TP.svg) TAP Portugal [](https://www.expedia.co.uk/Flights-Search?leg1=from:OPO,to:BRU,departure:31/12/2025TANYT&leg2=from:BRU,to:OPO,departure:07/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TP"}}]) - ![Air Europa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UX.svg) Air Europa [](https://www.expedia.co.uk/Flights-Search?leg1=from:OPO,to:BRU,departure:31/12/2025TANYT&leg2=from:BRU,to:OPO,departure:07/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UX"}}]) - ![KLM](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.co.uk/Flights-Search?leg1=from:OPO,to:BRU,departure:31/12/2025TANYT&leg2=from:BRU,to:OPO,departure:07/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) - ![Lufthansa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LH.svg) Lufthansa [](https://www.expedia.co.uk/Flights-Search?leg1=from:OPO,to:BRU,departure:31/12/2025TANYT&leg2=from:BRU,to:OPO,departure:07/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LH"}}]) - ![Swiss International Air Lines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LX.svg) Swiss International Air Lines [](https://www.expedia.co.uk/Flights-Search?leg1=from:OPO,to:BRU,departure:31/12/2025TANYT&leg2=from:BRU,to:OPO,departure:07/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LX"}}]) - ![Brussels Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_SN.svg) Brussels Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:OPO,to:BRU,departure:31/12/2025TANYT&leg2=from:BRU,to:OPO,departure:07/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"SN"}}]) - ![Iberia](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg) Iberia [](https://www.expedia.co.uk/Flights-Search?leg1=from:OPO,to:BRU,departure:31/12/2025TANYT&leg2=from:BRU,to:OPO,departure:07/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Porto (OPO) to Brussels (BRU) Prices were available within the past 7 days and start at £45 for one-way flights and £115 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Vueling Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/VY.GIF) Wed, 18 Mar - Wed, 25 Mar OPO Porto BRU Brussels £115 Return found 4 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:18/03/2026TANYT&leg2=from:BRU,to:OPO,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:114.65&airProductToken=AQptCjQI1rIBEgQ4NDc5GO5zIMFoKIP-hwMw5_6HAzhQQABYAWoIRkxZTElHSFRyCFBPV1ZZQ0xCCjUI1rIBEgQ4OTgwGMFoIKGkASjUgYgDMNuCiAM4UEAAWAFqCEZMWUxJR0hUcghQT1dWWUNMQgptCjUI1rIBEgQ4OTgzGKGkASDBaCiKyogDMIfLiAM4UEAAWAFqCEZMWUxJR0hUcghQT1dWWUNMQgo0CNayARIEODQ3OBjBaCDucyjNy4gDMLvMiAM4UEAAWAFqCEZMWUxJR0hUcghQT1dWWUNMQhIKCAsQARgIKgJWWRgBIgQIARABKAIwAw) ![Vueling Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/VY.GIF) Wed, 18 Mar - Wed, 25 Mar OPO Porto BRU Brussels £119 Return found 4 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:18/03/2026TANYT&leg2=from:BRU,to:OPO,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:118.21&airProductToken=AQptCjQI1rIBEgQ4NDc5GO5zIMFoKIP-hwMw5_6HAzhQQABYAWoIRkxZTElHSFRyCFBPV1ZZQ0xCCjUI1rIBEgQ4OTgwGMFoIKGkASjUgYgDMNuCiAM4UEAAWAFqCEZMWUxJR0hUcghQT1dWWUNMQgptCjUI1rIBEgQ4OTgzGKGkASDBaCiKyogDMIfLiAM4UEAAWAFqCEZMWUxJR0hUcghQT1dWWUNMQgo0CNayARIEODQ3NBjBaCDucyjS0IgDMMrRiAM4UEAAWAFqCEZMWUxJR0hUcghQT1dWWUNMQhIKCAsQARgIKgJWWRgBIgQIARABKAIwAw) ![Vueling Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/VY.GIF) Wed, 18 Mar - Wed, 25 Mar OPO Porto BRU Brussels £120 Return found 4 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:18/03/2026TANYT&leg2=from:BRU,to:OPO,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:119.99&airProductToken=AQptCjQI1rIBEgQ4NDc5GO5zIMFoKIP-hwMw5_6HAzhQQABYAWoIRkxZTElHSFRyCFBPV1ZZQ0xCCjUI1rIBEgQ4OTgwGMFoIKGkASjUgYgDMNuCiAM4UEAAWAFqCEZMWUxJR0hUcghQT1dWWUNMQgptCjUI1rIBEgQ4OTg3GKGkASDBaCiSyYgDMIrKiAM4T0AAWAFqCEZMWUxJR0hUcghPT1dWWUNMQgo0CNayARIEODQ3OBjBaCDucyjNy4gDMLvMiAM4T0AAWAFqCEZMWUxJR0hUcghPT1dWWUNMQhIKCAsQARgIKgJWWRgBIgQIARABKAIwAw) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Wed, 18 Mar - Wed, 25 Mar OPO Porto BRU Brussels £125 Return found 4 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:18/03/2026TANYT&leg2=from:BRU,to:OPO,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:124.81&airProductToken=AQphCi4I1bABEgQxMTQ2GO5zIIwYKJf5hwMw3fmHAzhOQABYAWoETElURXIGTllZTzVMCi8I1bABEgQxMTczGIwYIKGkASi3-ocDMM37hwM4TkABWAFqBExJVEVyBk5ZWU81TBIKCAEQARgBKgJVWBgBIgQIARABKAIoAygEMAE) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 7 Feb - Wed, 11 Feb OPO Porto BRU Brussels £127 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:07/02/2026TANYT&leg2=from:BRU,to:OPO,departure:11/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:126.60&airProductToken=AQpsCjQI1KABEgQxOTIxGO5zIIuSASiXwYQDMNPBhAM4VEAAWAFqB0RJU0NORVdyCFRGMERTQzA1CjQI1KABEgM2NDYYi5IBIKGkASirxoQDMNrHhAM4VEAAWAFqB0RJU0NORVdyCFRGMERTQzA1EgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwDQ) ![Vueling Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/VY.GIF) Sat, 21 Feb - Tue, 3 Mar OPO Porto BRU Brussels £128 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:21/02/2026TANYT&leg2=from:BRU,to:OPO,departure:03/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:127.70&airProductToken=AQpvCjUI1rIBEgQ4NDc5GO5zIMFoKOPkhQMwx-WFAzjEmAFAAFgBaghGTFlMSUdIVHIHRENPV0xQQgo2CNayARIEODk4MBjBaCChpAEotOiFAzC76YUDOMSYAUAAWAFqCEZMWUxJR0hUcgdEQ09XTFBCCm8KNgjWsgESBDg5ODUYoaQBIMFoKOfUhgMw49WGAzjEmAFAAFgBaghGTFlMSUdIVHIHRENPV0xQQgo1CNayARIEODQ3NBjBaCDucyiS2YYDMIrahgM4xJgBQABYAWoIRkxZTElHSFRyB0RDT1dMUEISCggLEAEYCCoCVlkYASIECAEQASgCMAM) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Sat, 7 Feb - Wed, 11 Feb OPO Porto BRU Brussels £129 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:07/02/2026TANYT&leg2=from:BRU,to:OPO,departure:11/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:128.74&airProductToken=AQppCjIIy5gBEgQxNTcwGO5zIICTASisv4QDMMzAhAM4R0AAWAFqBUxJR0hUcghHWUxGQkFMQQozCMuYARIEMTcwMxiAkwEgoaQBKPnAhAMwpsGEAzhHQAFYAWoFTElHSFRyCEdZTEZCQUxBEgoIARABGAEqAktMGAEiBAgBEAEoAigDKAQwDQ) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 7 Feb - Wed, 11 Feb OPO Porto BRU Brussels £130 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:07/02/2026TANYT&leg2=from:BRU,to:OPO,departure:11/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:129.70&airProductToken=AQpuCjUI1KABEgQxOTIxGO5zIIuSASiXwYQDMNPBhAM4VEAAWAFqCERJU0NPVU5UcghURjBEU0MwNQo1CNSgARIDNjQwGIuSASChpAEozsuEAzD4zIQDOFRAAVgBaghESVNDT1VOVHIIVEYwRFNDMDUSCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAB) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Fri, 6 Feb - Mon, 9 Feb OPO Porto BRU Brussels £132 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:06/02/2026TANYT&leg2=from:BRU,to:OPO,departure:09/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:131.60&airProductToken=AQplCjAIyYQBEgM1NTAY7nMgjBgouLuEAzCIvIQDOEFAAFgBagVCQVNJQ3IIQUROTkFPQjUKMQjJhAESAzYwMxiMGCChpAEo_sWEAzCPx4QDOEFAAVgBagVCQVNJQ3IIQUROTkFPQjQSCggBEAEYASoCSUIYASIECAEQASgCKAMoBDAN) ![Vueling Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/VY.GIF) Wed, 18 Mar - Wed, 25 Mar OPO Porto BRU Brussels £133 Return found 4 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:BRU,departure:18/03/2026TANYT&leg2=from:BRU,to:OPO,departure:25/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:132.74&airProductToken=AQptCjQI1rIBEgQ4NDc5GO5zIMFoKIP-hwMw5_6HAzhQQABYAWoIRkxZTElHSFRyCFBPV1ZZQ0xCCjUI1rIBEgQ4OTgwGMFoIKGkASjUgYgDMNuCiAM4UEAAWAFqCEZMWUxJR0hUcghQT1dWWUNMQhIKCAsQARgIKgJWWRgBIgQIARABKAIwAw) ## Find the cheapest month to fly from Porto (OPO) to Brussels (BRU) ### March is typically the cheapest month to fly From £55 - £205 per traveller. __Flight from Porto to Brussels route information__ | Origin airport | Dr. Francisco de Sa Carneiro | | ------------------- | ------------------------------------------------------------------------------------------------------------------------------------------- | | Destination airport | Brussels - National | | Airlines serving | Air Europa, Brussels Airlines, Iberia, KLM, Lufthansa, Scandinavian Airlines, Swiss International Air Lines, TAP Portugal, Vueling Airlines | | Return price | £115 | | Distance | 1464 km | | Average flight time | 3 hours 30 mins | ## Compare flights from Porto to Brussels easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Porto to Brussels. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Brussels - National in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Dr. Francisco de Sa Carneiro to Brussels - National. To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. Grab a great deal on your flight from Dr. Francisco de Sa Carneiro (OPO) to Brussels - National (BRU) The easiest way to view the best deals on flights from Porto to Brussels today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Dr. Francisco de Sa Carneiro to Brussels - National start at just £115 and range up to £133\. To find an even better deal, try - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Porto and Brussels - booking your flight during March, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper Why you should book your Porto to Brussels flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Dr. Francisco de Sa Carneiro to Brussels - National for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you. Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight. ## Frequently asked questions ### How much is a flight from Dr. Francisco de Sa Carneiro Airport (OPO) to Brussels - National Airport (BRU)? ### Do I need to pay a cancellation fee if I cancel my flight from Porto Airport to BRU? ### How do I find cheap flights from OPO to Brussels - National Airport (BRU) that have flexible change policies? ### How far is the flight from OPO to BRU? ### Which airlines fly direct from OPO to BRU? ### Are Dr. Francisco de Sa Carneiro Airport (OPO) to Brussels Airport flight tickets cheaper when they're purchased at the last minute? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [4 Star Hotels in Everberg ](https://www.expedia.co.uk/4Star-Everberg-Hotels.s40-0-d6349543.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Zaventem ](https://www.expedia.co.uk/5Star-Zaventem-Hotels.s50-0-d5191.Travel-Guide-Filter-Hotels) - 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