£130 Cheap Flights from Indianapolis (IND) to San Francisco (SFO)

View £130 flight on Wed, 20 May 2026Opens in a new window

Popular airlines from Indianapolis International Airport (IND) to San Francisco International Airport (SFO)

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Cheap Flights from Indianapolis (IND) to San Francisco (SFO)

Prices were available within the past 7 days and start at £130 for one-way flights and £254 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, 5 Jun - Sat, 6 Jun
IND
Indianapolis
SFO
San Francisco
£254 Return, found 5 days ago
£254
Return
found 5 days ago
Select Delta flight, departing Fri, 5 Jun from Indianapolis to San Francisco, returning Sat, 6 Jun, priced at £254 found 5 days ago
Alaska Airlines
Wed, 20 May - Wed, 27 May
IND
Indianapolis
SFO
San Francisco
£258 Return, found 4 days ago
£258
Return
found 4 days ago
Select Alaska Airlines flight, departing Wed, 20 May from Indianapolis to San Francisco, returning Wed, 27 May, priced at £258 found 4 days ago
Alaska Airlines
Tue, 2 Jun - Fri, 5 Jun
IND
Indianapolis
SFO
San Francisco
£290 Return, found 5 days ago
£290
Return
found 5 days ago
Select Alaska Airlines flight, departing Tue, 2 Jun from Indianapolis to San Francisco, returning Fri, 5 Jun, priced at £290 found 5 days ago
Alaska Airlines
Wed, 20 May - Wed, 27 May
IND
Indianapolis
SFO
San Francisco
£295 Return, found 4 days ago
£295
Return
found 4 days ago
Select Alaska Airlines flight, departing Wed, 20 May from Indianapolis to San Francisco, returning Wed, 27 May, priced at £295 found 4 days ago
Delta
Thu, 4 Jun - Sun, 7 Jun
IND
Indianapolis
SFO
San Francisco
£299 Return, found 5 days ago
£299
Return
found 5 days ago
Select Delta flight, departing Thu, 4 Jun from Indianapolis to San Francisco, returning Sun, 7 Jun, priced at £299 found 5 days ago
Delta
Thu, 4 Jun - Sun, 7 Jun
IND
Indianapolis
SFO
San Francisco
£305 Return, found 5 days ago
£305
Return
found 5 days ago
Select Delta flight, departing Thu, 4 Jun from Indianapolis to San Francisco, returning Sun, 7 Jun, priced at £305 found 5 days ago
Delta
Mon, 1 Jun - Fri, 5 Jun
IND
Indianapolis
SFO
San Francisco
£308 Return, found 5 days ago
£308
Return
found 5 days ago
Select Delta flight, departing Mon, 1 Jun from Indianapolis to San Francisco, returning Fri, 5 Jun, priced at £308 found 5 days ago
Alaska Airlines
Wed, 20 May - Wed, 27 May
IND
Indianapolis
SFO
San Francisco
£332 Return, found 4 days ago
£332
Return
found 4 days ago
Select Alaska Airlines flight, departing Wed, 20 May from Indianapolis to San Francisco, returning Wed, 27 May, priced at £332 found 4 days ago
United
Thu, 4 Jun - Sun, 7 Jun
IND
Indianapolis
SFO
San Francisco
£384 Return, found 5 days ago
£384
Return
found 5 days ago
Select United flight, departing Thu, 4 Jun from Indianapolis to San Francisco, returning Sun, 7 Jun, priced at £384 found 5 days ago
American Airlines
Thu, 4 Jun - Sun, 7 Jun
IND
Indianapolis
SFO
San Francisco
£412 Return, found 5 days ago
£412
Return
found 5 days ago
Select American Airlines flight, departing Thu, 4 Jun from Indianapolis to San Francisco, returning Sun, 7 Jun, priced at £412 found 5 days ago

Frequently asked questions

How much does a flight from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) cost?
One-way flights typically cost between £220 and £2,410 and return flights often range between £220 and £2,410. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.
What is the cheapest month to fly from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
September is typically the cheapest month to fly from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.), with average return fares of approximately £262. This is about 14% lower than the average price throughout the year. September often sees lower prices as the summer travel rush ends and before the holiday season begins, leading to reduced demand. Other cheap months to fly from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) include February and August.
Which airlines fly direct from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
Enter IND to SFO and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
To find a cheap flight from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The best airline to fly with from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) will differ from traveller to traveller. If you like to fly early, UA offers early morning flights. If price is the most important factor, UA typically offers the lowest fares. WN offers the most daily flights from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.), which is brilliant if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
Based on booking data from the past year, the cheapest months to fly from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) are typically September and February, with average return flights around £262. While these months offer great value, they aren't the most popular times to travel. If you're looking for a balance of good prices and more flight options, you might consider booking during months that are both affordable and have higher demand, though no single month perfectly aligns for both on this route. September still offers a good balance of potentially lower prices and pleasant weather in San Francisco.
How many flights per day from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
There are approximately 3 nonstop flights per day from Indianapolis Intl. (IND) to San Francisco Intl. (SFO). For even more choice, look at flights that include layovers. You'll find around 144 connecting flights per day. Some common connection points include O'Hare Intl. (ORD), Seattle - Tacoma Intl. (SEA), and Denver Intl. (DEN).
What is the earliest flight from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The earliest flight from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) typically departs at approximately 5:00 AM local time. This flight is operated by American Airlines and is a seasonal service active in June. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
You'll typically find the most flights from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) on a Thursday, with around 79 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include United Airlines, American Airlines, and Delta Air Lines. Flight schedules are consistent throughout the week.
What are the most popular departure times for flights from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The most popular departure times for flights from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) are in the early morning, from 6am to 9am. About 34% of passengers prefer this time. Many major carriers, including American Airlines, Delta Air Lines and United Airlines, offer flights during this window. This timing works well because you can get an early start to your travel day and arrive in San Francisco with plenty of time to settle in.
How long does it take to fly from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
A nonstop flight from IND to SFO typically takes around 5 hours, covering approximately 1,939 miles. Connecting flights on this route usually add 3 hours 50 minutes to your travel time. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
Select the "Business class" and "First class" filters when looking for IND to SFO flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How much is a business class flight from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
A non-stop, one-way business class flight from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) is usually around £723 - £2,027. Prices often fluctuate based on seasonality and how early you book. You may also be able to find a cheaper business class journey between Anaa (AAA) (AAA) to Toronto, ON (YYZ-Pearson Intl.) (YYZ) if you opt for a connecting flight.
How do I earn miles on a Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight with Expedia?
It's easy to earn miles on a Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Francisco from Indianapolis Intl. (IND)?
If you're planning to travel to San Francisco from Indianapolis Intl. (IND), you can fly directly into San Francisco Intl. (SFO) Some flights may connect through major hubs like Seattle - Tacoma Intl. (SEA), McCarran Intl. (LAS), O'Hare Intl. (ORD) before reaching San Francisco. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) at the last minute?
Typically, booking a last minute flight from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package?
Securing a Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
If you booked your Indianapolis, IN (IND-Indianapolis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Indianapolis Intl.
Destination airport
San Francisco Intl.
Return price
£253
Distance
3102 km
Average flight time
1 hour 57 mins

Book with confidence

Compare flights from Indianapolis to San Francisco easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Indianapolis to San Francisco. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Francisco Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Indianapolis Intl. to San Francisco Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Indianapolis Intl. (IND) to San Francisco Intl. (SFO)

The easiest way to view the best deals on flights from Indianapolis to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Indianapolis Intl. to San Francisco Intl. start at just £254 and range up to £412.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Indianapolis and San Francisco
  • booking your flight during June, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Indianapolis to San Francisco flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Indianapolis Intl. to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Indianapolis to San Francisco easily and book with confidence

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*Available to Expedia members.