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£429 Cheap Flights from Rome (FCO) to San Diego (SAN)

View £429 flight on Sat, 21 Nov 2026Opens in a new window

Popular airlines from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to San Diego Intl. Airport (SAN)

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Cheap Flights from Rome (FCO) to San Diego (SAN)

Prices were available within the past 7 days and start at £429 for one-way flights and £714 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Fri, 13 Nov - Mon, 23 Nov
FCO
Rome
SAN
San Diego
£714 Return, found 6 days ago
£714
Return
found 6 days ago
Select Iberia flight, departing Fri, 13 Nov from Rome to San Diego, returning Mon, 23 Nov, priced at £714 found 6 days ago
Iberia
Fri, 23 Oct - Mon, 2 Nov
FCO
Rome
SAN
San Diego
£717 Return, found 6 days ago
£717
Return
found 6 days ago
Select Iberia flight, departing Fri, 23 Oct from Rome to San Diego, returning Mon, 2 Nov, priced at £717 found 6 days ago
Iberia
Fri, 13 Nov - Mon, 23 Nov
FCO
Rome
SAN
San Diego
£722 Return, found 6 days ago
£722
Return
found 6 days ago
Select Iberia flight, departing Fri, 13 Nov from Rome to San Diego, returning Mon, 23 Nov, priced at £722 found 6 days ago
Iberia
Fri, 13 Nov - Mon, 23 Nov
FCO
Rome
SAN
San Diego
£723 Return, found 6 days ago
£723
Return
found 6 days ago
Select Iberia flight, departing Fri, 13 Nov from Rome to San Diego, returning Mon, 23 Nov, priced at £723 found 6 days ago
Iberia
Sat, 22 Aug - Sat, 29 Aug
FCO
Rome
SAN
San Diego
£727 Return, found 1 day ago
£727
Return
found 1 day ago
Select Iberia flight, departing Sat, 22 Aug from Rome to San Diego, returning Sat, 29 Aug, priced at £727 found 1 day ago
Lufthansa
Sat, 24 Oct - Mon, 2 Nov
FCO
Rome
SAN
San Diego
£746 Return, found 6 days ago
£746
Return
found 6 days ago
Select Lufthansa flight, departing Sat, 24 Oct from Rome to San Diego, returning Mon, 2 Nov, priced at £746 found 6 days ago
British Airways
Thu, 6 Aug - Wed, 30 Sept
FCO
Rome
SAN
San Diego
£752 Return, found 5 days ago
£752
Return
found 5 days ago
Select British Airways flight, departing Thu, 6 Aug from Rome to San Diego, returning Wed, 30 Sept, priced at £752 found 5 days ago
Brussels Airlines
Fri, 13 Nov - Mon, 23 Nov
FCO
Rome
SAN
San Diego
£758 Return, found 6 days ago
£758
Return
found 6 days ago
Select Brussels Airlines flight, departing Fri, 13 Nov from Rome to San Diego, returning Mon, 23 Nov, priced at £758 found 6 days ago
Alaska Airlines
Fri, 7 Aug - Wed, 16 Sept
FCO
Rome
SAN
San Diego
£759 Return, found 6 days ago
£759
Return
found 6 days ago
Select Alaska Airlines flight, departing Fri, 7 Aug from Rome to San Diego, returning Wed, 16 Sept, priced at £759 found 6 days ago
KLM
Sat, 12 Dec - Mon, 21 Dec
FCO
Rome
SAN
San Diego
£761 Return, found 1 day ago
£761
Return
found 1 day ago
Select KLM flight, departing Sat, 12 Dec from Rome to San Diego, returning Mon, 21 Dec, priced at £761 found 1 day ago

Frequently asked questions

How much does a flight from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) cost?
You can find one-way and return flights from FCO to SAN with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when FCO to SAN ticket fares go up or down.
What is the cheapest month to fly from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The cheapest months to fly from FCO to SAN are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
Enter FCO to SAN and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
Condor is one of the cheapest airlines offering connecting return flights from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.), with a layover in Frankfurt Intl. (FRA), with tickets starting from around £1068 for flights that can be booked for departure within the next year. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
To find a cheap flight from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
There are around 78 connecting flights per day from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.). Some common connection points include Seattle - Tacoma Intl. (SEA), Dublin (DUB), and Adolfo Suarez Madrid-Barajas (MAD).
What is the earliest flight from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The earliest flight from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) typically departs around 4:45 AM. This route is operated by TAP Portugal and American Airlines. This is a seasonal service, active only in May. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
You'll typically find the most flights from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) on a Wednesday, with around 59 flights available. This gives you a good selection of options for your journey. Major airlines on this route include American Airlines, United, and Delta. Flight schedules are fairly consistent throughout the week, so you'll have plenty of options no matter when you choose to fly.
What are the most popular departure times for flights from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The most popular departure times for flights from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) are in the early morning, from 6am to 9am. Many major carriers, including Lufthansa, British Airways and ITA Airways, offer flights during this window. Many travellers prefer this time as it allows for an early start to their journey.
How long does it take to fly from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
There are no nonstop flights from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.). For flights with one stop, you can expect the journey to take around 17 hours 48 minutes. If your flight has two or more stops, the travel time will be longer, typically around 20 hours 48 minutes. The distance covered on this route is approximately 10,251 kilometres. Keep in mind that actual flight times can vary due to factors like routing, weather, and wind patterns.
Can you fly business or first class from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
Yes, you can fly business class from Rome (FCO) to San Diego, CA (SAN).Airlines that offer business class service on this route include:
  • Swiss International Air Lines
  • Air Baltic
  • TAP Portugal
  • Lufthansa
  • Air France
  • Iberia
  • KLM
  • SAS
  • Brussels Airlines
  • ITA Airways
  • Aer Lingus
  • Air Europa
  • Alaska Airlines
  • British Airways
  • Air Canada
  • Med View Airlines
  • Icelandair
  • Condor
  • Delta
  • United
  • Austrian Airlines
  • Finnair
  • American Airlines
  • Helvetic Airways

How do I earn miles on a Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) flight with Expedia?
It's easy to earn miles on a Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Diego, CA (SAN) from Rome (FCO)?
If you're planning to travel to San Diego from Fiumicino - Leonardo da Vinci Intl. (FCO), you can fly directly into San Diego Intl. (SAN). Some flights may connect through major hubs like Adolfo Suarez Madrid-Barajas (MAD), Heathrow (LHR), or Frankfurt Intl. (FRA) before reaching San Diego. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) at the last minute?
Typically, booking a last minute flight from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package?
Securing a Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.)?
If you booked your Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) to San Diego, CA (SAN-San Diego Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Fiumicino - Leonardo da Vinci Intl.
Destination airport
San Diego Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, Austrian Airlines, British Airways, Brussels Airlines, Iberia, KLM, Lufthansa, Scandinavian Airlines
Return price
£714
Distance
10190 km

Book with confidence

Compare flights from Rome to San Diego easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Rome to San Diego. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Diego Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Fiumicino - Leonardo da Vinci Intl. to San Diego Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Fiumicino - Leonardo da Vinci Intl. (FCO) to San Diego Intl. (SAN)

The easiest way to view the best deals on flights from Rome to San Diego today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Fiumicino - Leonardo da Vinci Intl. to San Diego Intl. start at just £714 and range up to £761.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Rome and San Diego
  • booking your flight during November, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Rome to San Diego flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Fiumicino - Leonardo da Vinci Intl. to San Diego Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Rome to San Diego easily and book with confidence

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*Available to Expedia members.