£147 Cheap Flights from Detroit (DTW) to San Diego (SAN)

View £147 flight on Wed, 27 May 2026Opens in a new window

Flight 1

Popular airlines from Detroit Metropolitan Wayne County Airport (DTW) to San Diego Intl. Airport (SAN)

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Cheap Flights from Detroit (DTW) to San Diego (SAN)

Prices were available within the past 7 days and start at £147 for one-way flights and £295 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Alaska Airlines
Wed, 27 May - Tue, 9 Jun
DTW
Detroit
SAN
San Diego
£295 Return, found 2 days ago
£295
Return
found 2 days ago
Select Alaska Airlines flight, departing Wed, 27 May from Detroit to San Diego, returning Tue, 9 Jun, priced at £295 found 2 days ago
JetBlue Airways
Thu, 28 May - Sat, 30 May
DTW
Detroit
SAN
San Diego
£307 Return, found 2 days ago
£307
Return
found 2 days ago
Select JetBlue Airways flight, departing Thu, 28 May from Detroit to San Diego, returning Sat, 30 May, priced at £307 found 2 days ago
Alaska Airlines
Wed, 20 May - Wed, 27 May
DTW
Detroit
SAN
San Diego
£331 Return, found 5 days ago
£331
Return
found 5 days ago
Select Alaska Airlines flight, departing Wed, 20 May from Detroit to San Diego, returning Wed, 27 May, priced at £331 found 5 days ago
Alaska Airlines
Tue, 19 May - Tue, 2 Jun
DTW
Detroit
SAN
San Diego
£331 Return, found 2 days ago
£331
Return
found 2 days ago
Select Alaska Airlines flight, departing Tue, 19 May from Detroit to San Diego, returning Tue, 2 Jun, priced at £331 found 2 days ago
JetBlue Airways
Tue, 12 May - Wed, 27 May
DTW
Detroit
SAN
San Diego
£350 Return, found 2 days ago
£350
Return
found 2 days ago
Select JetBlue Airways flight, departing Tue, 12 May from Detroit to San Diego, returning Wed, 27 May, priced at £350 found 2 days ago
Alaska Airlines
Tue, 2 Jun - Sat, 6 Jun
DTW
Detroit
SAN
San Diego
£353 Return, found 5 days ago
£353
Return
found 5 days ago
Select Alaska Airlines flight, departing Tue, 2 Jun from Detroit to San Diego, returning Sat, 6 Jun, priced at £353 found 5 days ago
JetBlue Airways
Thu, 28 May - Sat, 30 May
DTW
Detroit
SAN
San Diego
£355 Return, found 2 days ago
£355
Return
found 2 days ago
Select JetBlue Airways flight, departing Thu, 28 May from Detroit to San Diego, returning Sat, 30 May, priced at £355 found 2 days ago
JetBlue Airways
Thu, 28 May - Sat, 30 May
DTW
Detroit
SAN
San Diego
£356 Return, found 2 days ago
£356
Return
found 2 days ago
Select JetBlue Airways flight, departing Thu, 28 May from Detroit to San Diego, returning Sat, 30 May, priced at £356 found 2 days ago
Alaska Airlines
Wed, 20 May - Wed, 27 May
DTW
Detroit
SAN
San Diego
£363 Return, found 5 days ago
£363
Return
found 5 days ago
Select Alaska Airlines flight, departing Wed, 20 May from Detroit to San Diego, returning Wed, 27 May, priced at £363 found 5 days ago
Delta
Thu, 9 Jul - Mon, 13 Jul
DTW
Detroit
SAN
San Diego
£398 Return, found 12 hours ago
£398
Return
found 12 hours ago
Select Delta flight, departing Thu, 9 Jul from Detroit to San Diego, returning Mon, 13 Jul, priced at £398 found 12 hours ago

Alternative airports near San Diego

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McClellan-Palomar CLD. Cheapest option available. Average driving time to city centre is 38 minutes. Flights from £455
CLD
McClellan-Palomar
Cheapest
Average driving time to city centre38 min
Flights from £455

Frequently asked questions

How much does a flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.) cost?
One-way flights typically cost between £432 and £1,370 and return flights often range between £777 and £2,102. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.
Which airlines fly direct from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
Enter DTW to SAN and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
To find a cheap flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
The best airline to fly with from Detroit Metropolitan Wayne County (DTW) to San Diego Intl. (SAN) will differ from traveller to traveller. If you like to fly early, DL offers early morning flights. If price is the most important factor, DL typically offers the lowest fares. DL offers the most daily flights from Detroit Metropolitan Wayne County (DTW) to San Diego Intl. (SAN), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
There are approximately 4 nonstop flights per day from Detroit Metropolitan Wayne County (DTW) to San Diego Intl. (SAN). For even more choice, look at flights that include layovers, as there are around 134 connecting flights per day. Some common connection points include Seattle - Tacoma Intl. (SEA), O'Hare Intl. (ORD), and Denver Intl. (DEN).
What is the earliest flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
The earliest flight from Detroit Metropolitan Wayne County (DTW) to San Diego Intl. (SAN) typically departs at approximately 5:00 AM local time, operated by American Airlines. This is a seasonal service active in May. An early departure like this can help you maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
You'll find the most flights from Detroit Metropolitan Wayne County (DTW) to San Diego Intl. (SAN) on a Friday, with around 76 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Delta Air Lines, American Airlines, and United Airlines. Flight schedules are consistent throughout the week, with Friday offering about 6% more flights than other days.
What are the most popular departure times for flights from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
The most popular departure times for flights from Detroit Metropolitan Wayne County (DTW) to San Diego Intl. (SAN) are in the early morning, from 6am to 9am. About 37% of passengers prefer this time. Many major carriers, including American Airlines, Delta and Southwest Airlines, offer flights during this window. This timing works well because you can get an early start to your travel day and arrive in San Diego with plenty of time to enjoy your destination.
How long does it take to fly from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
A nonstop flight from DTW to SAN typically takes around 4 hours 50 minutes, covering approximately 1,953 miles. Connecting flights on this route usually add 3 hours 30 minutes to your travel time. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
Select the "Business class" and "First class" filters when looking for DTW to SAN flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How much is a business class flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
A direct, return business class ticket from Detroit Metropolitan Wayne County (DTW) to San Diego Intl. (SAN) typically costs between £2,102 - £2,625. Prices often fluctuate based on seasonality and how early you book. You may also be able to find a cheaper business class journey between Anaa (AAA) (AAA) to Toronto, ON (YYZ-Pearson Intl.) (YYZ) if you opt for a connecting flight.
How do I earn miles on a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.) flight with Expedia?
It's easy to earn miles on a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Diego from Detroit Metropolitan Wayne County (DTW)?
From Detroit Metropolitan Wayne County (DTW), you can fly directly into San Diego Intl. (SAN) to reach San Diego. Some flights may connect through major hubs like Seattle - Tacoma Intl. (SEA), O'Hare Intl. (ORD), Midway Intl. (MDW) before reaching San Diego. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.) at the last minute?
Typically, booking a last minute flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package?
Securing a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.)?
If you booked your Detroit, MI (DTW-Detroit Metropolitan Wayne County) to San Diego, CA (SAN-San Diego Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Detroit Metropolitan Wayne County
Destination airport
San Diego Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, JetBlue Airways, United
Return price
£294
Distance
3124 km
Average flight time
1 hour 50 mins

Book with confidence

Compare flights from Detroit to San Diego easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Detroit to San Diego. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Diego Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Detroit Metropolitan Wayne County to San Diego Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Detroit Metropolitan Wayne County (DTW) to San Diego Intl. (SAN)

The easiest way to view the best deals on flights from Detroit to San Diego today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Detroit Metropolitan Wayne County to San Diego Intl. start at just £295 and range up to £398.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Detroit and San Diego
  • booking your flight during May, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Detroit to San Diego flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Detroit Metropolitan Wayne County to San Diego Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Detroit to San Diego easily and book with confidence

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*Available to Expedia members.