A grand historic building with a symmetrical facade, large central doors, and a flagpole.

£407 Cheap Flights from Cartagena (CTG) to Madrid (MAD)

View £407 flight on Fri, 6 Nov 2026Opens in a new window

Popular airlines from Rafael Nunez Intl. Airport (CTG) to Adolfo Suarez Madrid-Barajas Airport (MAD)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 25% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Cartagena (CTG) to Madrid (MAD)

Prices were available within the past 7 days and start at £407 for one-way flights and £656 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Fri, 20 Nov - Fri, 27 Nov
CTG
Cartagena
MAD
Madrid
£656 Return, found 2 days ago
£656
Return
found 2 days ago
Select Aeromexico flight, departing Fri, 20 Nov from Cartagena to Madrid, returning Fri, 27 Nov, priced at £656 found 2 days ago
World 2 Fly, S.L
Fri, 13 Nov - Fri, 20 Nov
CTG
Cartagena
MAD
Madrid
£665 Return, found 7 hours ago
£665
Return
found 7 hours ago
Select World 2 Fly, S.L flight, departing Fri, 13 Nov from Cartagena to Madrid, returning Fri, 20 Nov, priced at £665 found 7 hours ago
Hahn Air Technologies
Fri, 13 Nov - Fri, 20 Nov
CTG
Cartagena
MAD
Madrid
£713 Return, found 7 hours ago
£713
Return
found 7 hours ago
Select Hahn Air Technologies flight, departing Fri, 13 Nov from Cartagena to Madrid, returning Fri, 20 Nov, priced at £713 found 7 hours ago
Hahn Air Technologies
Fri, 23 Oct - Fri, 13 Nov
CTG
Cartagena
MAD
Madrid
£715 Return, found 5 days ago
£715
Return
found 5 days ago
Select Hahn Air Technologies flight, departing Fri, 23 Oct from Cartagena to Madrid, returning Fri, 13 Nov, priced at £715 found 5 days ago
World 2 Fly, S.L
Fri, 13 Nov - Fri, 20 Nov
CTG
Cartagena
MAD
Madrid
£739 Return, found 7 hours ago
£739
Return
found 7 hours ago
Select World 2 Fly, S.L flight, departing Fri, 13 Nov from Cartagena to Madrid, returning Fri, 20 Nov, priced at £739 found 7 hours ago
KLM
Sun, 15 Nov - Sun, 22 Nov
CTG
Cartagena
MAD
Madrid
£742 Return, found 7 hours ago
£742
Return
found 7 hours ago
Select KLM flight, departing Sun, 15 Nov from Cartagena to Madrid, returning Sun, 22 Nov, priced at £742 found 7 hours ago
World 2 Fly, S.L
Fri, 2 Oct - Fri, 16 Oct
CTG
Cartagena
MAD
Madrid
£742 Return, found 17 hours ago
£742
Return
found 17 hours ago
Select World 2 Fly, S.L flight, departing Fri, 2 Oct from Cartagena to Madrid, returning Fri, 16 Oct, priced at £742 found 17 hours ago
Hahn Air Technologies
Fri, 20 Nov - Fri, 27 Nov
CTG
Cartagena
MAD
Madrid
£752 Return, found 2 days ago
£752
Return
found 2 days ago
Select Hahn Air Technologies flight, departing Fri, 20 Nov from Cartagena to Madrid, returning Fri, 27 Nov, priced at £752 found 2 days ago
KLM
Fri, 13 Nov - Fri, 20 Nov
CTG
Cartagena
MAD
Madrid
£768 Return, found 7 hours ago
£768
Return
found 7 hours ago
Select KLM flight, departing Fri, 13 Nov from Cartagena to Madrid, returning Fri, 20 Nov, priced at £768 found 7 hours ago
LATAM Airlines Group
Fri, 13 Nov - Fri, 20 Nov
CTG
Cartagena
MAD
Madrid
£785 Return, found 7 hours ago
£785
Return
found 7 hours ago
Select LATAM Airlines Group flight, departing Fri, 13 Nov from Cartagena to Madrid, returning Fri, 20 Nov, priced at £785 found 7 hours ago

Frequently asked questions

How much does a flight from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) cost?
You can find cheap one-way flights from £407 and cheap return flights from £656 CTG to MAD with Expedia. One-way flights typically cost between £1179 and £2401. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when CTG to MAD ticket fares go up or down.
What is the cheapest month to fly from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
The cheapest months to fly from CTG to MAD are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
There are 2 airlines offering direct flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas). Here are the carriers:
  • Plus Ultra Lineas Aereas S. A. operates 7 direct flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) every week.
  • Welcome Air operates 7 direct flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) every week.
What is the cheapest airline that flies from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
Welcome Air is one of the cheapest airlines offering nonstop return flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas), with tickets starting from around £752 for flights that can be booked for departure within the next year. Air Transat is one of the cheapest airlines offering connecting return flights on this route, with tickets starting from around £854. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
To find a cheap flight from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
The best airline to fly with from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) will differ from traveler to traveler. If you like to fly early, Plus Ultra Lineas Aereas S. A. offers early morning flights. If price is the most important factor, Plus Ultra Lineas Aereas S. A. typically offers the lowest fares. Avianca offers the most daily flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
While direct flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) are minimal, you'll find approximately 72 connecting flights per day. This gives you plenty of options to choose from. Some common connection points include El Dorado Intl. (BOG), Tocumen Intl. (PTY), and Jose Maria Cordova Intl. (MDE).
What is the earliest flight from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
The earliest flight from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) typically departs at around 12:55 AM local time, operated by Plus Ultra Lineas Aereas S. A. This is a seasonal service, active in January, February, March, November, and December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
You'll typically find the most flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) on a Thursday, with around 45 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Avianca, LATAM Airlines Group, and Copa. Flight schedules are fairly consistent throughout the week, so you'll have plenty of choices regardless of the day you choose to fly.
What are the most popular departure times for flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
The most popular departure times for flights from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) are between 12pm and 3pm. Many major carriers, including Avianca, LATAM Airlines Group and American Airlines, offer flights during this window. Many travellers prefer this because it allows for a morning in Cartagena before heading to the airport, and you'll arrive in Madrid in the evening, ready to settle in.
How long does it take to fly from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
A direct flight from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) typically takes around 9 hours 48 minutes, covering a distance of approximately 7,733 kilometres. If you opt for a one-stop flight, the journey usually extends to about 12 hours 48 minutes. Flights with two or more stops will take even longer, typically around 18 hours 18 minutes. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some extra time when planning your trip.
Can you fly business or first class from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
Yes, you can fly business class between CTG and MAD. Airlines that offer business class service on this route include:
  • Avianca
  • Plus Ultra Lineas Aereas S. A.
  • KLM
  • Edelweiss Air
  • Aeromexico
  • Copa
  • American Airlines
How do I earn miles on a Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight with Expedia?
It's easy to earn miles on a Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Madrid (MAD) from Cartagena (CTG)?
If you're planning to travel to Madrid from Rafael Nunez Intl. (CTG), you can fly directly into Adolfo Suarez Madrid-Barajas (MAD) which offers international flights and connections. Some flights may connect through major hubs like Tocumen Intl. (PTY), El Dorado Intl. (BOG), or Jose Maria Cordova Intl. (MDE) before reaching Madrid. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) at the last minute?
Typically, booking a last minute flight from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight and hotel package?
Securing a Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
If you booked your Cartagena (CTG-Rafael Núñez Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

0
Origin airport
Rafael Núñez Intl.
Destination airport
Adolfo Suárez Madrid-Barajas
Airlines serving
Aeromexico, Air Canada, Copa, Hahn Air Technologies, Iberia, KLM, LATAM Airlines Group, Lufthansa, World 2 Fly, S.L, avianca
Return price
£656
Distance
7687 km

Book with confidence

Compare flights from Cartagena to Madrid easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Cartagena to Madrid. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Adolfo Suárez Madrid-Barajas in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Rafael Núñez Intl. to Adolfo Suárez Madrid-Barajas.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Rafael Núñez Intl. (CTG) to Adolfo Suárez Madrid-Barajas (MAD)

The easiest way to view the best deals on flights from Cartagena to Madrid today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Rafael Núñez Intl. to Adolfo Suárez Madrid-Barajas start at just £656 and range up to £785.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Cartagena and Madrid
  • booking your flight during November, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Cartagena to Madrid flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Rafael Núñez Intl. to Adolfo Suárez Madrid-Barajas for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Cartagena to Madrid easily and book with confidence

Explore a world of travel with Expedia

*Available to Expedia members.