Title: £441 Cheap Flights from Panama City to Madrid (PTY to MAD) - Expedia.co.uk ![](https://images.trvl-media.com/place/178281/66e8bb1c-004f-4aa2-adf9-023a08d84cc3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/178281/66e8bb1c-004f-4aa2-adf9-023a08d84cc3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £441 Cheap Flights from Panama City (PTY) to Madrid (MAD) [View £441 flight on Sun, 1 Feb 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:PTY,to:MAD,departure:01/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:440.80&airProductToken=AQpjCjAIwawBEgI1NxjvxAEgwTMomoSEAzD-hIQDOFNAAFgBagVMSUdIVHIIU1pPQjFCUlIKLwjBrAESAjQ2GMEzIIwYKN2KhAMwnI-EAzhTQAFYAWoFTElHSFRyCFNaT0IxQlJSEgoIARABGAEqAkFWGAEiBAgBEAEoAigDKAQwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Tocumen Intl. Airport (PTY) to Madrid - ![Air Europa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UX.svg) Air Europa [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:MAD,departure:29/01/2026TANYT&leg2=from:MAD,to:PTY,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UX"}}]) - ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:MAD,departure:29/01/2026TANYT&leg2=from:MAD,to:PTY,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![Iberia](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg) Iberia [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:MAD,departure:29/01/2026TANYT&leg2=from:MAD,to:PTY,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) - ![KLM](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:MAD,departure:29/01/2026TANYT&leg2=from:MAD,to:PTY,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:MAD,departure:29/01/2026TANYT&leg2=from:MAD,to:PTY,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:MAD,departure:29/01/2026TANYT&leg2=from:MAD,to:PTY,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Air France](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:MAD,departure:29/01/2026TANYT&leg2=from:MAD,to:PTY,departure:05/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Panama City (PTY) to Madrid (MAD) Prices were available within the past 7 days and start at £441 for one-way flights and £463 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Air France](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AF.gif) Sun, 31 May - Sun, 7 Jun PTY Panama City MAD Madrid £463 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:31/05/2026TANYT&leg2=from:MAD,to:PTY,departure:07/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:462.30&airProductToken=AQpmCjEIwYwBEgM0NzUY78QBIOIwKJLBjgMwg8aOAzhYQABYAWoFTElHSFRyCFhSTDBBSExJCjEIwYwBEgQxNDAwGOIwIIwYKLTIjgMwu8mOAzhMQAFYAWoFTElHSFRyCFhSTDBBSExJCmYKMQjBjAESBDEzMDEYjBgg4jAo7IePAzDpiI8DOExAAFgBagVMSUdIVHIIR1JMMEFITEkKMQjBjAESAzQ3NBjiMCDvxAEouYmPAzDNjo8DOEdAAVgBagVMSUdIVHIIR1JMMEFITEkSCggBEAEYASoCQUYYASIECAEQASgCKAMoBDAN) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Sun, 31 May - Sun, 7 Jun PTY Panama City MAD Madrid £482 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:31/05/2026TANYT&leg2=from:MAD,to:PTY,departure:07/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:481.50&airProductToken=AQozCjEIyYQBEgMyNTgY78QBIIwYKNbAjgMwpMWOAzhBQABYAWoFQkFTSUNyCEFBTjBOUUI3CjMKMQjJhAESAzI1NxiMGCDvxAEow4mPAzDcjo8DOEFAAFgBagVCQVNJQ3IIQUFOME5RQjcSCggCEAEYAioCSUIYASIECAEQASgCKAMoBDAN) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Sat, 7 Nov - Sat, 28 Nov PTY Panama City MAD Madrid £484 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:07/11/2026TANYT&leg2=from:MAD,to:PTY,departure:28/11/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:484.00&airProductToken=AQozCjEIyYQBEgMyNTgY78QBIIwYKJfJnAMw9M2cAzhBQABYAWoFQkFTSUNyCEFBTjBOUUI3CjMKMQjJhAESAzI1NxiMGCDvxAEov6-eAzDYtJ4DOEFAAFgBagVCQVNJQ3IIQUFOME5RQjcSCggCEAEYAioCSUIYASIECAEQASgCKAMoBDAN) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 12 Nov - Sun, 15 Nov PTY Panama City MAD Madrid £489 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:12/11/2026TANYT&leg2=from:MAD,to:PTY,departure:15/11/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:488.30&airProductToken=AQovCi0I1bABEgI1NhjvxAEgjBgo9oCdAzC1hZ0DOFpAAFgBagRMSVRFcgZaRkxZNUwKLwotCNWwARICNTUYjBgg78QBKPKcnQMw7aGdAzhaQABYAWoETElURXIGWkZMWTVMEgoIARABGAEqAlVYGAEiBAgBEAEoAigDKAQwAQ) ![Air France](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AF.gif) Fri, 1 May - Sun, 17 May PTY Panama City MAD Madrid £489 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:01/05/2026TANYT&leg2=from:MAD,to:PTY,departure:17/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:488.89&airProductToken=AQp_Cj4IwYwBEgQ4NjQwGO_EASDgXCjo64sDMOztiwM4VkAAWAFqBUxJR0hUcghWUkwwQUhMSXoKCMSYARIEODY0MAo9CMGMARIEMzU4NRjgXCCMGCju7osDMOfyiwM4VkABWAFqBUxJR0hUcghWUkwwQUhMSXoKCMSYARIEMzU4NQpmCjEIwYwBEgQxMzAxGIwYIOIwKMybjQMwyZyNAzhMQABYAWoFTElHSFRyCEdSTDBBSExJCjEIwYwBEgM0NzQY4jAg78QBKJmdjQMwraKNAzhHQAFYAWoFTElHSFRyCEdSTDBBSExJEgoIARABGAEqAkFGGAEiBAgBEAEoAigDKAQwDQ) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Sun, 25 Jan - Tue, 3 Feb PTY Panama City MAD Madrid £491 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:25/01/2026TANYT&leg2=from:MAD,to:PTY,departure:03/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:491.00&airProductToken=AQpoCjIIy5gBEgM3NTgY78QBIICTASjxtYMDMOK6gwM4WEAAWAFqBUxJR0hUcghYUkwwQUhMSQoyCMuYARIEMTUwNRiAkwEgjBgo87uDAzCJvYMDOExAAVgBagVMSUdIVHIIWFJMMEFITEkKaAoyCMuYARIEMTUwNhiMGCCAkwEotpeEAzDRmIQDOExAAFgBagVMSUdIVHIIWFJMMEFITEkKMgjLmAESAzc1NxiAkwEg78QBKIyghAMwqqWEAzhYQAFYAWoFTElHSFRyCFhSTDBBSExJEgoIARABGAEqAktMGAEiBAgBEAEoAigDKAQwDQ) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Thu, 4 Jun - Mon, 8 Jun PTY Panama City MAD Madrid £493 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:04/06/2026TANYT&leg2=from:MAD,to:PTY,departure:08/06/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:492.20&airProductToken=AQpoCjIIy5gBEgM3NTgY78QBIICTASi27I4DMKLxjgM4WEAAWAFqBUxJR0hUcghYUkwwQUhMSQoyCMuYARIEMTUwMxiAkwEgjBgop_uOAzDC_I4DOExAAVgBagVMSUdIVHIIWFJMMEFITEkKaAoyCMuYARIEMTUwOBiMGCCAkwEo9paPAzCMmI8DOExAAFgBagVMSUdIVHIIWFJMMEFITEkKMgjLmAESAzc1NxiAkwEg78QBKM-ejwMw3qOPAzhYQAFYAWoFTElHSFRyCFhSTDBBSExJEgoIARABGAEqAktMGAEiBAgBEAEoAigDKAQwDQ) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Thu, 12 Nov - Sun, 15 Nov PTY Panama City MAD Madrid £494 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:12/11/2026TANYT&leg2=from:MAD,to:PTY,departure:15/11/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:493.20&airProductToken=AQpoCjIIy5gBEgM3NTgY78QBIICTASjR_5wDMMKEnQM4WEAAWAFqBUxJR0hUcghYUkwwQUhMSQoyCMuYARIEMTUwORiAkwEgjBgogYmdAzChip0DOExAAVgBagVMSUdIVHIIWFJMMEFITEkKaAoyCMuYARIEMTUwMBiMGCCAkwEozJidAzDimZ0DOExAAFgBagVMSUdIVHIIWFJMMEFITEkKMgjLmAESAzc1NxiAkwEg78QBKIybnQMwqqCdAzhYQAFYAWoFTElHSFRyCFhSTDBBSExJEgoIARABGAEqAktMGAEiBAgBEAEoAigDKAQwDQ) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Sun, 25 Jan - Tue, 3 Feb PTY Panama City MAD Madrid £495 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:25/01/2026TANYT&leg2=from:MAD,to:PTY,departure:03/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:494.70&airProductToken=AQpoCjIIy5gBEgM3NTgY78QBIICTASjxtYMDMOK6gwM4WEAAWAFqBUxJR0hUcghYUkwwQUhMSQoyCMuYARIEMTUwNRiAkwEgjBgo87uDAzCJvYMDOExAAVgBagVMSUdIVHIIWFJMMEFITEkKtAEKMgjLmAESBDE1MDAYjBgggJMBKKyShAMwwpOEAzhMQABYAWoFTElHSFRyCEdSTDBBSExJCj4Iy5gBEgQzNTc4GICTASDiMCi8lYQDMJGWhAM4TEABWAFqBUxJR0hUcghHUkwwQUhMSXoKCMGMARIEMzU3OAo-CMuYARIEMjI5NhjiMCDvxAEo0paEAzDmm4QDOEdAAVgBagVMSUdIVHIIR1JMMEFITEl6CgjBjAESBDIyOTYSCggBEAEYASoCS0wYASIECAEQASgCKAMoBDAN) ![Turkish Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TK.gif) Wed, 29 Apr - Thu, 14 May PTY Panama City MAD Madrid £601 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:MAD,departure:29/04/2026TANYT&leg2=from:MAD,to:PTY,departure:14/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:601.00&airProductToken=AQpGCiEI1JYBEgM5MDQY78QBIMicASiI2YsDMIXfiwM4V0AAWAEKIQjUlgESBDE4NTcYyJwBIIwYKNXkiwMw3uaLAzhXQAFYAQpGCiEI1JYBEgQxODYwGIwYIMicASjZ_IwDMNj-jAM4V0AAWAEKIQjUlgESAzgwMBjInAEg78QBKLCDjQMwnYuNAzhXQAFYARIKCAEQARgBKgJUSxgBIgQIARABKAQwAQ) ## Find the cheapest month to fly from Panama City (PTY) to Madrid (MAD) ### February is typically the cheapest month to fly From £477 - £749 per traveller. ## Alternative airports near Madrid Prices were available within the past 7 days. Prices and availability are subject to change. [](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:MAD,departure:29/01/2026TANYT&leg2=from:MAD,to:PTY,departure:20/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) MAD Adolfo Suarez Madrid-Barajas CheapestClosest 20 min [Flights from £632 ](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:MAD,departure:29/01/2026TANYT&leg2=from:MAD,to:PTY,departure:20/02/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) ## Frequently asked questions ### How much is a flight from Panama Airport to Adolfo Suarez Madrid-Barajas Airport (MAD)? ### Do I need to pay a cancellation fee if I cancel my flight from PTY to Adolfo Suarez Madrid-Barajas Airport (MAD)? ### How do I find cheap flights from Panama Airport to MAD that have flexible change policies? ### How far is the flight from Tocumen Intl. Airport (PTY) to Madrid Airport? ### Which airlines fly direct from Panama Airport to Adolfo Suarez Madrid-Barajas Airport (MAD)? ### Are Panama Airport to Madrid–Barajas Airport flight tickets cheaper when they're purchased at the last minute? ## Travel information | Origin airport | Tocumen Intl. | | ------------------- | ------------------------------------------------------------------------- | | Destination airport | Adolfo Suárez Madrid-Barajas | | Airlines serving | Aeromexico, Air Europa, Air France, Copa, Iberia, KLM, Lufthansa, avianca | | Return price | £462 | | Distance | 8109 km | | Average flight time | 15 hours 50 mins | ## Book with confidence # Compare flights from Panama City to Madrid easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Panama City to Madrid. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Adolfo Suárez Madrid-Barajas in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Tocumen Intl. to Adolfo Suárez Madrid-Barajas. To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. Grab a great deal on your flight from Tocumen Intl. (PTY) to Adolfo Suárez Madrid-Barajas (MAD) The easiest way to view the best deals on flights from Panama City to Madrid today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Tocumen Intl. to Adolfo Suárez Madrid-Barajas start at just £463 and range up to £601\. To find an even better deal, try - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Panama City and Madrid - booking your flight during May, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper Why you should book your Panama City to Madrid flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Tocumen Intl. to Adolfo Suárez Madrid-Barajas for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you. Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. 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