Cheap Flights from Charleston (CHS) to Key West (EYW)

Popular airlines from Charleston Intl. Airport (CHS) to Key West Intl. Airport (EYW)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 25% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Charleston (CHS) to Key West (EYW)

Prices were available within the past 7 days and start at for one-way flights and £173 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Breeze Airways
Wed, 8 Jul - Fri, 10 Jul
CHS
Charleston
EYW
Key West
£173 Return, found 4 days ago
£173
Return
found 4 days ago
Select Breeze Airways flight, departing Wed, 8 Jul from Charleston to Key West, returning Fri, 10 Jul, priced at £173 found 4 days ago
Breeze Airways
Wed, 8 Jul - Fri, 10 Jul
CHS
Charleston
EYW
Key West
£197 Return, found 4 days ago
£197
Return
found 4 days ago
Select Breeze Airways flight, departing Wed, 8 Jul from Charleston to Key West, returning Fri, 10 Jul, priced at £197 found 4 days ago
Breeze Airways
Wed, 8 Jul - Fri, 10 Jul
CHS
Charleston
EYW
Key West
£203 Return, found 4 days ago
£203
Return
found 4 days ago
Select Breeze Airways flight, departing Wed, 8 Jul from Charleston to Key West, returning Fri, 10 Jul, priced at £203 found 4 days ago
Breeze Airways
Wed, 8 Jul - Fri, 10 Jul
CHS
Charleston
EYW
Key West
£227 Return, found 4 days ago
£227
Return
found 4 days ago
Select Breeze Airways flight, departing Wed, 8 Jul from Charleston to Key West, returning Fri, 10 Jul, priced at £227 found 4 days ago
Breeze Airways
Wed, 8 Jul - Fri, 10 Jul
CHS
Charleston
EYW
Key West
£245 Return, found 4 days ago
£245
Return
found 4 days ago
Select Breeze Airways flight, departing Wed, 8 Jul from Charleston to Key West, returning Fri, 10 Jul, priced at £245 found 4 days ago
Breeze Airways
Wed, 8 Jul - Fri, 10 Jul
CHS
Charleston
EYW
Key West
£276 Return, found 4 days ago
£276
Return
found 4 days ago
Select Breeze Airways flight, departing Wed, 8 Jul from Charleston to Key West, returning Fri, 10 Jul, priced at £276 found 4 days ago

Frequently asked questions

How do I find cheap flights from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.)?
To find a cheap flight from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.)?
There are approximately 22 connecting flights per day from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.). Some common connection points include Hartsfield-Jackson Atlanta Intl. (ATL), Charlotte-Douglas Intl. (CLT), and O'Hare Intl. (ORD).
What is the earliest flight from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.)?
The earliest flight from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) typically departs at approximately 5:00 AM local time, operated by American Airlines. This is a seasonal service active in April and May. An early departure like this can help you maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.)?
You'll find the most flights from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) on a Friday, with around 19 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include American Airlines, Delta Air Lines, and United Airlines. Fridays offer notably more flight options compared to other days of the week, making it a good day to plan your trip.
What are the most popular departure times for flights from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.)?
The most popular departure times for flights from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) are in the early morning, between 6am and 9am. About 47% of passengers prefer this time. American Airlines, Delta Air Lines and United Airlines offer flights during this window. Many travelers prefer these early flights so they can arrive at their destination and have more of the day to enjoy.
How long does it take to fly from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.)?
Flights from CHS to EYW with one stop typically take around 6 hours 50 minutes, covering approximately 585 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.)?
Select the "Business class" and "First class" filters when looking for CHS to EYW flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) flight with Expedia?
It's easy to earn miles on a Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Key West from Charleston Intl. (CHS)?
If you're planning to travel to Key West from Charleston Intl. (CHS), you can fly into Key West Intl. (EYW) Some flights may connect through major hubs like LaGuardia (LGA), John F. Kennedy Intl. (JFK), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Key West. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) at the last minute?
Typically, booking a last minute flight from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) flight and hotel package?
Securing a Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.)?
If you booked your Charleston, SC (CHS-Charleston Intl.) to Key West, FL (EYW-Key West Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Charleston Intl.
Destination airport
Key West Intl.
Return price
£173
Distance
935 km

Book with confidence

Compare flights from Charleston to Key West easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Charleston to Key West. Operating between them flights per day, 6 airlines cover the route. And fly direct, getting you to Key West Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Charleston Intl. to Key West Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Charleston Intl. (CHS) to Key West Intl. (EYW)

The easiest way to view the best deals on flights from Charleston to Key West today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Charleston Intl. to Key West Intl. start at just £173 and range up to £276.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Charleston and Key West
  • booking your flight during July, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Charleston to Key West flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Charleston Intl. to Key West Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Charleston to Key West easily and book with confidence

Explore a world of travel with Expedia

*Available to Expedia members.