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£380 Cheap Flights from Brussels (BRU) to San Francisco (SFO)

View £380 flight on Wed, 4 Nov 2026Opens in a new window

Popular airlines from Brussels Airport (BRU) to San Francisco International Airport (SFO)

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Cheap Flights from Brussels (BRU) to San Francisco (SFO)

Prices were available within the past 7 days and start at £380 for one-way flights and £512 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

ITA Airways
Wed, 2 Sept - Wed, 16 Sept
BRU
Brussels
SFO
San Francisco
£512 Return, found 23 hours ago
£512
Return
found 23 hours ago
Select ITA Airways flight, departing Wed, 2 Sept from Brussels to San Francisco, returning Wed, 16 Sept, priced at £512 found 23 hours ago
ITA Airways
Mon, 7 Sept - Wed, 16 Sept
BRU
Brussels
SFO
San Francisco
£524 Return, found 2 days ago
£524
Return
found 2 days ago
Select ITA Airways flight, departing Mon, 7 Sept from Brussels to San Francisco, returning Wed, 16 Sept, priced at £524 found 2 days ago
Aer Lingus
Wed, 18 Nov - Wed, 2 Dec
BRU
Brussels
SFO
San Francisco
£526 Return, found 2 days ago
£526
Return
found 2 days ago
Select Aer Lingus flight, departing Wed, 18 Nov from Brussels to San Francisco, returning Wed, 2 Dec, priced at £526 found 2 days ago
ITA Airways
Mon, 7 Sept - Wed, 16 Sept
BRU
Brussels
SFO
San Francisco
£536 Return, found 2 days ago
£536
Return
found 2 days ago
Select ITA Airways flight, departing Mon, 7 Sept from Brussels to San Francisco, returning Wed, 16 Sept, priced at £536 found 2 days ago
Aer Lingus
Thu, 1 Oct - Sat, 24 Oct
BRU
Brussels
SFO
San Francisco
£549 Return, found 4 days ago
£549
Return
found 4 days ago
Select Aer Lingus flight, departing Thu, 1 Oct from Brussels to San Francisco, returning Sat, 24 Oct, priced at £549 found 4 days ago
TAP Portugal
Fri, 4 Dec - Sat, 12 Dec
BRU
Brussels
SFO
San Francisco
£586 Return, found 22 hours ago
£586
Return
found 22 hours ago
Select TAP Portugal flight, departing Fri, 4 Dec from Brussels to San Francisco, returning Sat, 12 Dec, priced at £586 found 22 hours ago
Brussels Airlines
Mon, 30 Nov - Wed, 9 Dec
BRU
Brussels
SFO
San Francisco
£603 Return, found 4 days ago
£603
Return
found 4 days ago
Select Brussels Airlines flight, departing Mon, 30 Nov from Brussels to San Francisco, returning Wed, 9 Dec, priced at £603 found 4 days ago
Lufthansa
Wed, 2 Sept - Wed, 16 Sept
BRU
Brussels
SFO
San Francisco
£603 Return, found 23 hours ago
£603
Return
found 23 hours ago
Select Lufthansa flight, departing Wed, 2 Sept from Brussels to San Francisco, returning Wed, 16 Sept, priced at £603 found 23 hours ago
KLM
Mon, 7 Sept - Tue, 22 Sept
BRU
Brussels
SFO
San Francisco
£611 Return, found 4 days ago
£611
Return
found 4 days ago
Select KLM flight, departing Mon, 7 Sept from Brussels to San Francisco, returning Tue, 22 Sept, priced at £611 found 4 days ago
British Airways
Sat, 29 Aug - Sat, 12 Sept
BRU
Brussels
SFO
San Francisco
£612 Return, found 1 day ago
£612
Return
found 1 day ago
Select British Airways flight, departing Sat, 29 Aug from Brussels to San Francisco, returning Sat, 12 Sept, priced at £612 found 1 day ago

Alternative airports near San Francisco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to San Francisco Intl. SFO. Cheapest and Closest option available. Average driving time to city centre is 19 minutes. Flights from £603
SFO
San Francisco Intl.
CheapestClosest
Average driving time to city centre19 min
Flights from £603

Find the cheapest month to fly from Brussels (BRU) to San Francisco (SFO)

November is typically the cheapest month to fly

From £505 - £647 per traveller.

Frequently asked questions

How much does a flight from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.) cost?
You can find one-way and return flights from BRU to SFO with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when BRU to SFO ticket fares go up or down.
What is the cheapest month to fly from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.)?
The cheapest months to fly from BRU to SFO are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.)?
Enter BRU to SFO and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Brussels (BRU) to San Francisco, CA (SFO)?
To find a cheap flight from Brussels (BRU) to San Francisco, CA (SFO), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.)?
The earliest flight from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.) typically departs around 5:45 AM. This service is operated by SAS. This is a seasonal service, active in April, May, June, August, September, and October. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.)?
There are no nonstop flights from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.). The distance between these two cities is approximately 8,895 kilometers. Flights with one stop typically take around 14 hours 30 minutes. If your journey involves two or more stops, you can expect the travel time to be longer, usually around 20 hours 48 minutes. Keep in mind that actual flight times can vary due to factors like layover duration, routing, and wind patterns.
Can you fly business or first class from Brussels (BRU) to San Francisco, CA (SFO)?
Select the "Business class" and "First class" filters when looking for Brussels (BRU) to San Francisco, CA (SFO) flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.) flight with Expedia?
It's easy to earn miles on a Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Francisco, CA (SFO) from Brussels (BRU)?
If you're planning to travel to San Francisco from Brussels - National (BRU), you can fly directly into San Francisco Intl. (SFO). Some flights may connect through major hubs like Heathrow (LHR), Frankfurt Intl. (FRA), or Humberto Delgado (LIS) before reaching San Francisco. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.) at the last minute?
Typically, booking a last minute flight from Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package?
Securing a Brussels (BRU-Brussels - National) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Brussels (BRU) to San Francisco, CA (SFO)?
If you booked your Brussels (BRU) to San Francisco, CA (SFO) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Brussels - National
Destination airport
San Francisco Intl.
Airlines serving
Aer Lingus, Air Canada, Austrian Airlines, British Airways, Brussels Airlines, ITA Airways, Iberia, Icelandair, KLM, LOT-Polish Airlines, Lufthansa, Scandinavian Airlines, Swiss International Air Lines, TAP Portugal, Turkish Airlines
Return price
£512
Distance
8842 km

Book with confidence

Compare flights from Brussels to San Francisco easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Brussels to San Francisco. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Francisco Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Brussels - National to San Francisco Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Brussels - National (BRU) to San Francisco Intl. (SFO)

The easiest way to view the best deals on flights from Brussels to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Brussels - National to San Francisco Intl. start at just £512 and range up to £807.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Brussels and San Francisco
  • booking your flight during September, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Brussels to San Francisco flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Brussels - National to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Brussels to San Francisco easily and book with confidence

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*Available to Expedia members.