Uruguay Street
Visit Uruguay Street
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Price found within the past 48 hours. Click for updated prices.
Megapolis Hotel Panamá
San Francisco
Price was £996, price is now £783 per person
£783
per person
17 Jul - 20 Jul
found 24 hours ago
Return flight included
Port of Spain (POS) to Panama City (PTY)
8.4/10 Very Good! (1,523 reviews)
The spa was amazing so relaxing. The breakfast buffet had an assortment of things to eat but it’s better to get there in the am when the food is fresh. Great room with an amazing view! The kid pool was very dirty though I’m talking about bugs and this whitish film. I hope they also have more amenities such as the club and kids area open up. Seems like still recovering from covid. But overall I would stay again.
Reviewed on 8 May 2026
Central Hotel Panama Casco Viejo
Casco Viejo
Price was £1,399, price is now £1,128 per person
£1,128
per person
29 Jun - 2 Jul
found 1 day ago
Return direct flight included
London (LON) to Panama City (PTY)
9.2/10 Wonderful! (1,010 reviews)
Very nice and clean hotel in the centralized area. It is very safe to walk all over the place.
Reviewed on 11 May 2026
Sofitel Legend Casco Viejo, Panama City
Casco Viejo
Price was £1,041, price is now £870 per person
£870
per person
17 Jul - 20 Jul
found 24 hours ago
Return flight included
Port of Spain (POS) to Panama City (PTY)
9.8/10 Exceptional! (645 reviews)
Staff was exceptional. Location was perfect in Old Town. Will come back and stay here. It was wonderful.
Reviewed on 11 May 2026
Tours & day trips
See all 430 activities
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
Activity duration is 8 hours and 15 minutes
9.4 out of 10 with 71 reviews
Free cancellation available
Private & custom tours
See all 152 activities
EXPLORE PANAMA City 100% Private + Old Town + Canal + Poin
Activity duration is 6 hours
10.0 out of 10 with 20 reviews
Free cancellation available
Adventure & outdoor
See all 110 activities
Visit San Blas Paradise: Day Tour to 4 Islands with Lunch & Drink
Activity duration is 14 hours
8.8 out of 10 with 58 reviews
Free cancellation available
Cruises & boat tours
See all 66 activities
From Panama City: Monkey Islands Tour on Gatun Lake
Activity duration is 4 hours and 30 minutes
9.4 out of 10 with 59 reviews
Free cancellation available
Wildlife & nature
See all 46 activitiesFrom Panama City: Monkey Islands Tour on Gatun Lake
Activity duration is 4 hours and 30 minutes
9.4 out of 10 with 59 reviews
Free cancellation available
Popular places to visit
Soho City Center
You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's shops or seek out its local tours.
Avenida Balboa
3.5/5(9 reviews)
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Cinta Costera
4/5(5 reviews)
After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside.
Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's casinos or seek out its local tours.
Multiplaza Pacific Mall
4.5/5(8 reviews)
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Iglesia del Carmen
4/5(1 review)
You can find out about the history of Panama City with a trip to Iglesia del Carmen. Stroll along the seaside in this vibrant area or visit its top-notch restaurants.
Top Hotel Deals
Check availability on hotels close to Uruguay Street
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The Executive Hotel
Calle 52 Panama City Panama
Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
Principe Hotel and Suites
Via Argentina Panama City Panama
Hyatt Regency Panama City
Calle 52 and Ricardo Arias Panama City Panamá Province
Hotel Ojos del Rio
calle 41 este Panama City Panama
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
W Panama
Calle Aquilino de la Guardia & Calle 50 Panama City
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.