Uruguay Street

A coastal cityscape with a prominent church tower, a river, and distant mountains.
A statue of a man on horseback, a white building with balconies, and a well-lit plaza.
A historic street with a church tower, colorful buildings, and a sunset sky.
A coastal city skyline with modern skyscrapers and a rocky shoreline.
A nighttime cityscape with illuminated skyscrapers and busy roads.

Plan a trip to see Uruguay Street

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Tocumen Airport
Price was £1,402, price is now £1,025 per person
£1,025
per person
24 Jan - 30 Jan
found 8 hours ago
Return direct flight included
London (LHR) to Panama City (PTY)
8.6/10 Excellent! (1,824 reviews)
The best hotel when you need to stay near the airport in Panama. I booked this hotel for my mom, she had to stay overnight in Panama, before her next flight. Hotel offers shuttle services and the staff are always very helpful.

Reviewed on 9 Nov 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was £1,808, price is now £1,083 per person
£1,083
per person
24 Jan - 30 Jan
found 8 hours ago
Return direct flight included
London (LHR) to Panama City (PTY)
8.6/10 Excellent! (1,803 reviews)
Nice

Reviewed on 11 Nov 2026

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was £1,396, price is now £1,031 per person
£1,031
per person
24 Jan - 30 Jan
found 8 hours ago
Return direct flight included
London (LHR) to Panama City (PTY)
9/10 Wonderful! (6,099 reviews)
Such a shame that I have to give a review like this. This hotel has so much potential except for one thing that hasn't changed for years. The smell in the corridors and sometimes rooms is terrible from the humidity. It is so easy to freshen this up and fix it but nobody has bothered. Also the wireless is much too slow and inconsistent on the property. Fix both these things and it is a 5 star experience and very good pricing to include a very large breakfast buffet

Reviewed on 11 Nov 2026

Stay near popular Uruguay Street attractions

Uruguay Street

8.2/10 (656 reviews)
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Top Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Hotel Riu Plaza Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Megapolis Hotel Panamá
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
The Executive Hotel
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Waldorf Astoria Panama
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Calle 52 and Ricardo Arias Panama City Panamá Province
Hyatt Regency Panama City
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Principe Hotel and Suites
Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District

4.5 out of 5
C. Aquilino de la Guardia Panama City Panamá Province
Hotel Dann Carlton Marinn Place Panama Financial District
Hotel Mio Panama

Hotel Mio Panama

3 out of 5
panama Panama City panama
Hotel Mio Panama
See all 1,510 properties in Uruguay Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.