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Check prices for these dates

Tonight
12 May - 13 May
Tomorrow
13 May - 14 May
This weekend
15 May - 17 May
Next weekend
22 May - 24 May

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Our top choices for Uptown hotels

Breakfast, dinner and brunch served

The Principal Hotel

The Principal Hotel
3.5 star property
19.1 mi from Uptown
9.8 out of 10, Exceptional, (262 reviews)
"Highly recommend will stay again!"
United States
Mark
The price is £83
includes taxes & fees
14 May - 15 May
The Principal Hotel
Lobby

Comfort Inn Alton near I-255

Comfort Inn Alton near I-255
2.5 star property
18.1 mi from Uptown
7.6 out of 10, Good, (542 reviews)
"Staff is always welcoming and quick to respond to any needs. This venue has existed for a few years but the facility is well kept. There was a sign at the front desk stating that the pool was out of service, but I don't ask why or for how long it would be out. Room and food service areas were clean. This is great place to stay and have some money left in your pocket when you depart! Thanks for another great stay Comfort Inn 👍👍"
United States
Dave
The price is £75
includes taxes & fees
31 May - 1 Jun
Comfort Inn Alton near I-255
Suite, 1 King Bed, Non Smoking (One-Bedroom, Honeymoon) | Jetted bathtub

Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
2.5 star property
17.7 mi from Uptown
8.0 out of 10, Very good, (655 reviews)
"Easy safe neighborhood. I have stayed more than once. Thoughtful front desk staff put me away from the busy sports team rooms."
United States
Eugenia
The price is £81
includes taxes & fees
18 May - 19 May
Seasons Inn & Suites Highland
Exterior

Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
12.4 mi from Uptown
9.0 out of 10, Wonderful, (1,013 reviews)
"Good breakfast! Nice place to stay"
United States
Chrisandra
The price is £95
includes taxes & fees
19 May - 20 May
Best Western Plus MidAmerica Hotel
Property entrance

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
17.5 mi from Uptown
9.0 out of 10, Wonderful, (1,554 reviews)
"Great place to stay!"
United States
Cassady
The price is £73
includes taxes & fees
3 Jun - 4 Jun
River City Casino & Hotel
Gazebo

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
8.5 mi from Uptown
8.6 out of 10, Excellent, (697 reviews)
"Staff very friendly."
United States
Kellie
The price is £122
includes taxes & fees
14 May - 15 May
Country Hearth Inn & Suites Edwardsville St. Louis
Exterior

Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
13 mi from Uptown
8.0 out of 10, Very good, (321 reviews)
"Breakfast was great! Staff was friendly, rooms were clean and the parking was spacious "
United States
Nancy
The price is £101
includes taxes & fees
25 May - 26 May
Comfort Inn & Suites Saint Louis Lafayette Square
Indoor pool

Best Western Troy Hotel

Best Western Troy Hotel
2.5 star property
6.3 mi from Uptown
8.0 out of 10, Very good, (964 reviews)
"Very accommodating, and a great staff!"
United States
Caleb
The price is £73
includes taxes & fees
26 May - 27 May
Best Western Troy Hotel
Exterior

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
6.2 mi from Uptown
9.4 out of 10, Exceptional, (770 reviews)
"Great place to stay and get good sleep and an excellent breakfast."
United States
debbie
The price is £96
includes taxes & fees
25 May - 26 May
Holiday Inn Express Troy by IHG
Indoor pool

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
6.2 mi from Uptown
8.0 out of 10, Very good, (1,000 reviews)
"The hotel was ready to access, rooms were adequate and breakfast was good. "
United States
Teresa
The price is £59
includes taxes & fees
21 May - 22 May
Super 8 by Wyndham Troy IL/St. Louis Area
Room, 1 Queen Bed, Jetted Tub | Blackout curtains, free WiFi, bed sheets

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
7.6 mi from Uptown
7.8 out of 10, Good, (660 reviews)
"Clean room, staff, great hot breakfast daily"
United States
Jonathan
The price is £49
includes taxes & fees
24 May - 25 May
Red Lion Inn & Suites Pontoon Beach
Property amenity

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
11.1 mi from Uptown
9.6 out of 10, Exceptional, (3,423 reviews)
"Nice hotel, helpful staff, and excellent location."
United States
JEFF
The price is £140
includes taxes & fees
27 May - 28 May
Drury Plaza Hotel St. Louis at the Arch
Lobby

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
11 mi from Uptown
8.6 out of 10, Excellent, (4,030 reviews)
"Everything wonderful.. so close to everything.. easy walking distance and the food was delicious any restaurant in the Hyatt "
United States
Anamelik
The price is £110
includes taxes & fees
25 May - 26 May
Hyatt Regency St. Louis at The Arch
Lobby

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights
3.0 star property
4.5 mi from Uptown
9.2 out of 10, Wonderful, (1,015 reviews)
"Great room great breakfast very clean."
United States
Ron
The price is £101
includes taxes & fees
24 May - 25 May
Drury Inn & Suites St. Louis Fairview Heights
Free daily continental breakfast

Days Inn by Wyndham Troy IL

Days Inn by Wyndham Troy IL
2.0 star property
6 mi from Uptown
7.8 out of 10, Good, (322 reviews)
"The location is kind of awkward. I had pre-registered online which didn’t mean a thing once I got there I had to pay a $50 hotel fee that supposedly someday I will get back. The breakfast was bare. Basics in the room was just as basic definitely would would not go back"
United States
cathy
The price is £57
includes taxes & fees
18 May - 19 May
Days Inn by Wyndham Troy IL
Indoor pool

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
15.9 mi from Uptown
9.2 out of 10, Wonderful, (1,001 reviews)
"Loved everything about this property! It was clean, the staff was very pleasant and breakfast was great! Will stay again :)"
United States
Angelia J
The price is £114
includes taxes & fees
25 May - 26 May
Hampton Inn & Suites St. Louis at Forest Park
Lobby

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
6.8 mi from Uptown
8.4 out of 10, Very good, (845 reviews)
"Great place"
United States
Rogelio
The price is £90
includes taxes & fees
18 May - 19 May
Comfort Inn Edwardsville - St. Louis
Economy Single Room, Non Smoking | Free WiFi, bed sheets

Indian Mound Motel

Indian Mound Motel
2.5 star property
6 mi from Uptown
8.2 out of 10, Very good, (189 reviews)
"Friendly staff, not far from the city. I would definitely stay there again!"
United States
Samantha
The price is £55
includes taxes & fees
26 May - 27 May
Indian Mound Motel
Lobby

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
12 mi from Uptown
8.6 out of 10, Excellent, (1,007 reviews)
"Location to amenities was great and the staff was very friendly and welcoming. The hotel was very clean but seemed dated. We had a wonderful time and would definitely recommend it! "
United States
Keith
The price is £139
includes taxes & fees
27 May - 28 May
St. Louis Union Station Hotel, Curio Collection by Hilton
Exterior

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
8.6 mi from Uptown
9.2 out of 10, Wonderful, (868 reviews)
"The staff is friendly regardless of the time you arrive. We have stayed here a few times and each time they have been wonderful"
United States
Judy
The price is £122
includes taxes & fees
25 May - 26 May
Holiday Inn Express & Suites Edwardsville by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.
Aerial view of the iconic Gateway Arch and Mississippi River with urban skyline and bridges, Downtown St. Louis, Missouri, United States.

Eastport

While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.

early morning Cityscape of St. Louis skyline in Missouri state

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and Gateway Fun Park.

Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and FanDuel Sportsbook and Horse Racing.

Top Uptown Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

6/10 Okay
"Hs"
Isaac 2-night trip
Posted 1 hour ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

When is the best time to go to Uptown?
The best time to go to Uptown is from late spring (May) to early autumn (September), when the weather is most pleasant for exploring the area.

During these months, you'll find comfortable temperatures, typically ranging from 18°C to 28°C, which is ideal for walking around and enjoying outdoor attractions. The longer daylight hours also mean more time for sightseeing and relaxing by the lakefront. This period also sees various outdoor events and festivals, adding to the local experience.

Couples looking for a romantic getaway will appreciate the warmer months when they can take leisurely strolls along the lakefront or enjoy an evening meal at one of the many alfresco dining spots. The mild evenings are superb for catching a show at the historic venues in the district.

Solo travellers will find late spring and early autumn convenient for exploring Uptown's diverse offerings without the extreme heat or cold.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Uptown.
How can I save on a Uptown hotel booking with Expedia?
Members always get our best prices. Find our best Uptown hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Uptown hotel?
Hotel prices in Uptown often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.