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Check prices for these dates

Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

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Our top choices for Uptown hotels

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

1. Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
Eastport, 1.6 mi from Uptown
9.6 out of 10, Exceptional, (1,002 reviews)
"Best bacon .."
United States
Wayne
The price is £96
includes taxes & fees
11 Oct - 12 Oct
Drury Inn & Suites St. Louis Collinsville
A modern hotel room with a large bed, a blue chair, and a wall-mounted TV.

2. Days Inn by Wyndham Collinsville/St. Louis

Days Inn by Wyndham Collinsville/St. Louis
2.5 star property
Eastport, 1.7 mi from Uptown
7.4 out of 10, Good, (1,001 reviews)
"Very clean and comfortable place to stay."
United States
Gary
The price is £56
includes taxes & fees
29 Sept - 30 Sept
Days Inn by Wyndham Collinsville/St. Louis
A multi-story hotel with a covered entrance, stone pillars, and a parking lot.

3. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
3.0 star property
Eastport, 1.8 mi from Uptown
7.4 out of 10, Good, (1,006 reviews)
"Clean room, cheerful staff very helpful!!"
United States
Donna
The price is £80
includes taxes & fees
29 Sept - 30 Sept
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
A lobby with checkered armchairs, a reception desk, a plant, and a tiled floor.

4. Americas Best Value Inn Collinsville St. Louis

Americas Best Value Inn Collinsville St. Louis
2.0 star property
1.4 mi from Uptown
6.4 out of 10, (976 reviews)
"Beautiful Sunset"
United States
Jason
The price is £46
includes taxes & fees
11 Oct - 12 Oct
Americas Best Value Inn Collinsville St. Louis
A buffet area with a wooden counter, various food items, and a coffee station.

5. Comfort Inn Collinsville near St. Louis

Comfort Inn Collinsville near St. Louis
2.5 star property
Eastport, 1.7 mi from Uptown
8.6 out of 10, Excellent, (1,003 reviews)
"Good place to stay food and stores near by !"
United States
Jose Rene
The price is £93
includes taxes & fees
19 Oct - 20 Oct
Comfort Inn Collinsville near St. Louis
A lobby with a central table, seating area, and a stone pillar with a mirror.

6. DoubleTree by Hilton Collinsville - St. Louis

DoubleTree by Hilton Collinsville - St. Louis
4.0 star property
Eastport, 1.6 mi from Uptown
8.2 out of 10, Very good, (1,001 reviews)
"The staff at this property was bar none, they were awesome. 👍"
United States
katie
The price is £107
includes taxes & fees
18 Oct - 19 Oct
DoubleTree by Hilton Collinsville - St. Louis
A hotel room with two beds, a desk, a chair, and a TV.

7. Hampton Inn Collinsville

Hampton Inn Collinsville
2.5 star property
Eastport, 1.7 mi from Uptown
8.4 out of 10, Very good, (737 reviews)
"Very clean and helpful staff."
United States
Ria
The price is £93
includes taxes & fees
28 Oct - 29 Oct
Hampton Inn Collinsville
A hotel room with a bed, two bedside lamps, a cityscape painting, a wooden headboard, and a brown chair.

8. Super 8 by Wyndham Collinsville St. Louis

Super 8 by Wyndham Collinsville St. Louis
2.0 star property
Eastport, 1.7 mi from Uptown
7.0 out of 10, Good, (1,003 reviews)
"Very pleasant staff"
United States
Anthony
The price is £63
includes taxes & fees
5 Oct - 6 Oct
Super 8 by Wyndham Collinsville St. Louis
A bar area with a wooden bar counter, multiple stools, and shelves stocked with bottles.

9. Radisson Hotel Fairview Heights - St. Louis

Radisson Hotel Fairview Heights - St. Louis
3.0 star property
4.3 mi from Uptown
7.4 out of 10, Good, (701 reviews)
"Staff was great."
United States
Clint
The price is £78
includes taxes & fees
28 Sept - 29 Sept
Radisson Hotel Fairview Heights - St. Louis
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows offering views of the outside.

10. Best Western Troy Hotel

Best Western Troy Hotel
2.5 star property
6.3 mi from Uptown
8.0 out of 10, Very good, (1,002 reviews)
"Amazing experience, food options right next to hotel, great staff, clean room!"
United States
joshua
The price is £75
includes taxes & fees
29 Sept - 30 Sept
Best Western Troy Hotel
A modern lounge area with a sectional sofa, ottomans, and a round table.

11. Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights
3.0 star property
4.5 mi from Uptown
9.2 out of 10, Wonderful, (1,031 reviews)
"Clean rooms, friendly staff, and the complimentary dinner & drinks were a great perk."
United States
Arameia
The price is £95
includes taxes & fees
5 Oct - 6 Oct
Drury Inn & Suites St. Louis Fairview Heights
A modern hotel lobby with a sofa, chairs, a round table, and a decorative wall with geometric patterns.

12. Holiday Inn St. Louis Fairview Heights by IHG

Holiday Inn St. Louis Fairview Heights by IHG
3.0 star property
4.5 mi from Uptown
8.6 out of 10, Excellent, (716 reviews)
"We always stay here when we are in town"
United States
Melvin H
The price is £101
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn St. Louis Fairview Heights by IHG
A hotel room with a bed, a desk with a television, a chair, a desk lamp, and a wall-mounted rack with keys.

13. Red Roof Inn St Louis - Troy, IL

Red Roof Inn St Louis - Troy, IL
2.0 star property
6.3 mi from Uptown
7.8 out of 10, Good, (1,007 reviews)
"Clean room, staff has been great, breakfast has a good selection."
United States
crystal
The price is £54
includes taxes & fees
4 Oct - 5 Oct
Red Roof Inn St Louis - Troy, IL
A hotel room with a large mirror, a bathtub, a bedside table with a lamp, and a green bed.

14. Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh
3.0 star property
5.6 mi from Uptown
7.4 out of 10, Good, (1,004 reviews)
"Location great"
United States
Laura
The price is £54
includes taxes & fees
18 Oct - 19 Oct
Quality Inn O'Fallon - St. Louis - Shiloh
A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

15. Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
6.8 mi from Uptown
8.4 out of 10, Very good, (951 reviews)
"Great place to stop for a hotel room"
United States
Cynthia
The price is £83
includes taxes & fees
18 Oct - 19 Oct
Comfort Inn Edwardsville - St. Louis
A modern kitchen with marble countertops, a built-in coffee station, and a seating area with metal chairs and tables.

16. Days Inn by Wyndham Troy IL

Days Inn by Wyndham Troy IL
2.0 star property
6 mi from Uptown
7.8 out of 10, Good, (345 reviews)
"Check in was easy. The room was much larger than I expected. There were places in the room that could have used a little more attention from the cleaning staff, ie behind the bathroom door and tops of the picture frames, etc. It was surprising quiet and the bed was very comfortable. We would stay there again."
United States
Carol
The price is £59
includes taxes & fees
1 Oct - 2 Oct
Days Inn by Wyndham Troy IL
A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

17. Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
6.2 mi from Uptown
9.4 out of 10, Exceptional, (837 reviews)
"Great place and great breakfast"
United States
Donald
The price is £106
includes taxes & fees
28 Oct - 29 Oct
Holiday Inn Express Troy by IHG
An indoor swimming pool with a lifeguard chair, a lifebuoy, and a mural of a beach scene.

18. Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
6.2 mi from Uptown
8.2 out of 10, Very good, (1,005 reviews)
"Everything was very clean breakfast was adequate staff was great We enjoyed our stay"
United States
Jacqueline
The price is £53
includes taxes & fees
4 Oct - 5 Oct
Super 8 by Wyndham Troy IL/St. Louis Area
A hotel room with two beds, each with a headboard, bedside tables, lamps, and a desk with a chair.

19. Econo Lodge Inn & Suites Fairview Heights - St. Louis

Econo Lodge Inn & Suites Fairview Heights - St. Louis
2.0 star property
4.5 mi from Uptown
7.4 out of 10, Good, (650 reviews)
"Great place and location very clean"
United States
devon
The price is £55
includes taxes & fees
26 Oct - 27 Oct
Econo Lodge Inn & Suites Fairview Heights - St. Louis
A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

20. Hampton Inn O'Fallon

Hampton Inn O'Fallon
2.5 star property
6.8 mi from Uptown
9.2 out of 10, Wonderful, (876 reviews)
"Really nice"
United States
Edmond
The price is £100
includes taxes & fees
19 Oct - 20 Oct
Hampton Inn O'Fallon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.
An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.

Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.

A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.

Top Uptown Hotel Reviews

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

8/10 Good
"Hotel was in great shape with a solid good tasting breakfast. Toughest thing with the hotel is valet only parking & location being near many homeless."
Ryan 1-night trip
Posted 2 hours ago
Tru By Hilton St. Louis Downtown

Frequently asked questions

When is the best time to go to Uptown?
The best time to go to Uptown is from late spring (May) to early autumn (September), when the weather is most pleasant for exploring the area.

During these months, you'll find comfortable temperatures, typically ranging from 18°C to 28°C, which is ideal for walking around and enjoying outdoor attractions. The longer daylight hours also mean more time for sightseeing and relaxing by the lakefront. This period also sees various outdoor events and festivals, adding to the local experience.

Couples looking for a romantic getaway will appreciate the warmer months when they can take leisurely strolls along the lakefront or enjoy an evening meal at one of the many alfresco dining spots. The mild evenings are superb for catching a show at the historic venues in the district.

Solo travellers will find late spring and early autumn convenient for exploring Uptown's diverse offerings without the extreme heat or cold.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Uptown.
How much is the nightly rate at a Uptown hotel?
Hotel prices in Uptown often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.