Uptown Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Top hotels in Uptown
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is £142 per night from 29 Jun to 30 Jun
£142
29 Jun - 30 Jun
includes taxes & fees
8.6/10 Excellent! (4,154 reviews)
"Great room!"
Reviewed on 26 Jun 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is £88 per night from 26 Jul to 27 Jul
£88
26 Jul - 27 Jul
includes taxes & fees
8.8/10 Excellent! (3,250 reviews)
"Great place. Staff was very nice and helpful. Breakfast was really good . Parking was a bit confusing at first but is great to have parking. Not free on the weekends but still good."
Reviewed on 27 Jun 2026
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is £151 per night from 28 Jun to 29 Jun
£151
28 Jun - 29 Jun
includes taxes & fees
9.6/10 Exceptional! (3,520 reviews)
"Clean rooms, good breakfast, friendly staff"
Reviewed on 27 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Uptown attractions
Things to do
St. Louis Premium Small Group Tour With Arch & River Cruise
£119
per adult
84% of travellers recommend
St Louis Self-Guided Driving and Walking Audio Tour
£13
per traveller
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.