Title: Midtown Travel Guide: Best of Midtown, St. Louis Travel 2026 | Expedia.co.uk [Hotels in Midtown](https://expedia.co.uk/Midtown-Hotels.d553248635976008329.Travel-Guide-Hotels)[Flights to St. Louis](https://expedia.co.uk/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Midtown Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Midtown.d553248635976008329.Car-Hire-Guide)[Midtown Holidays](https://expedia.co.uk/Midtown.d553248635976008329.Holidays-City-Breaks) # Midtown Travel Guide ## St. Louis ![Midtown](https://mediaim.expedia.com/destination/9/8b783ab839a2184e9ca1c96805126ab3.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Photo by throwingsofas](https://mediaim.expedia.com/destination/2/3febf84b7fb94acf71a065a377d2c25e.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by throwingsofas](https://mediaim.expedia.com/destination/2/3febf84b7fb94acf71a065a377d2c25e.jpg) ![Photo by Karissa Krull](https://mediaim.expedia.com/destination/2/a3fc8cc73ac9a977b6b1b42013f73bd9.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Karissa Krull](https://mediaim.expedia.com/destination/2/a3fc8cc73ac9a977b6b1b42013f73bd9.jpg) ![Photo by Linda Garrison](https://mediaim.expedia.com/destination/2/166320a9f8834615520e178864091da9.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Linda Garrison](https://mediaim.expedia.com/destination/2/166320a9f8834615520e178864091da9.jpg) ![Photo by Sophie R](https://mediaim.expedia.com/destination/2/e3ba8d7e0b0beade08d22b9005e59981.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) [Photo by Sophie R](https://mediaim.expedia.com/destination/2/e3ba8d7e0b0beade08d22b9005e59981.jpg) ## Visit Midtown Things to do Hotels Where to stay [St. Louis travel guide](https://expedia.co.uk/St-Louis.dx178309) --- ### Popular places to visit ![St. Louis University](https://mediaim.expedia.com/destination/9/8b783ab839a2184e9ca1c96805126ab3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis University Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theatre scene. [](https://expedia.co.uk/St-Louis-University-Midtown.d502875.Attraction) ![Scott Joplin House State Historic Site](https://mediaim.expedia.com/destination/2/91a4803394311fb0d81a80bc248fcd5c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Scott Joplin House State Historic Site Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's acclaimed theatre scene or attend a baseball game. [](https://expedia.co.uk/Scott-Joplin-House-State-Historic-Site-St-Louis.d553248621555612572.Attraction) ![Union Station, St. Louis, MO](https://images.trvl-media.com/place/502868/8704491b-9324-4c56-89ed-94a638702313.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Union Station You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's acclaimed art galleries or attend a baseball game. [](https://expedia.co.uk/St-Louis-Union-Station-St-Louis.d502868.Attraction) ![St. Louis Cardinals Baseball. ](https://images.trvl-media.com/place/3284/67189e41-0060-455b-85a9-ab65c9125a63.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Busch Stadium Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game. [](https://expedia.co.uk/Busch-Stadium-St-Louis.d502872.Attraction) ![Gateway Arch showing a city, city views and skyline](https://images.trvl-media.com/place/502855/34e3411a-eeba-4fa1-95fe-3ad9b54938f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Gateway Arch Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark. [](https://expedia.co.uk/Gateway-Arch-Downtown-St-Louis.d502855.Attraction) ![St. Louis Zoo](https://images.trvl-media.com/place/502878/51adfd0a-5175-4aa9-aa40-2221835ea3ae.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Zoo In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world. [](https://expedia.co.uk/St-Louis-Zoo-St-Louis.d502878.Attraction) ### Things to do ![St. Louis: Gateway Ghouls and Hauntings Walking Tour](https://mediaim.expedia.com/localexpert/47668485/dd78fc5b-2837-423e-80a2-c4dfd8151a08.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Ghost Tour: Sinister Sins & Shadows £24 per adult [](https://expedia.co.uk/things-to-do/st-louis-ghost-tour-sinister-sins-shadows.a47668485.activity-details) ![Downtown St. Louis Smartphone Guided Audio Walking Tour App](https://mediaim.expedia.com/localexpert/49595158/04b4ccdd-3590-44c6-ae14-398df578c2e0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Downtown St. Louis Smartphone Guided Audio Walking Tour App £6 per adult [](https://expedia.co.uk/things-to-do/downtown-st-louis-smartphone-guided-audio-walking-tour-app.a49595158.activity-details) ![Step into the shadows and discover the haunting tales of our city's past.](https://mediaim.expedia.com/localexpert/5257552/b4659624-7f65-40c9-a170-6266a1de13ce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour £22 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-ghost-tours-sinister-sins-shadows-ghost-tour.a5257552.activity-details) ![Best of St. Louis Small Group Tour w/ Arch & River Cruise](https://mediaim.expedia.com/localexpert/46051486/4ca2bb68-86bc-4a3d-a7eb-e432157373a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Best of St. Louis Small Group Tour w/ Arch & River Cruise £125 per adult **84%** of travellers recommend [](https://expedia.co.uk/things-to-do/best-of-st-louis-small-group-tour-w-arch-river-cruise.a46051486.activity-details) ![St Louis Self-Guided Driving and Walking Audio Tour](https://mediaim.expedia.com/localexpert/49269846/95dbaecc-d0df-4a0c-a007-7dc95eddf58f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Self-Guided Driving and Walking Audio Tour £11 per traveller [](https://expedia.co.uk/things-to-do/st-louis-self-guided-driving-and-walking-audio-tour.a49269846.activity-details) ![St. Louis Premium Driving Tour with Boat Ride & Arch](https://mediaim.expedia.com/localexpert/47712556/5e48de69-a78b-4315-bccd-6ae9dafd98a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Premium Driving Tour with Boat Ride & Arch £129 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-premium-driving-tour-with-boat-ride-arch.a47712556.activity-details) [See all activities in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities) --- ## Top hotels in Midtown ![Element St. Louis Midtown](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/3e830499_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Element St. Louis Midtown 3763 Forest Park Avenue St. Louis MO £117 23 Jan - 24 Jan includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ... 9/10 Wonderful! (659 reviews) The staff was really nice but the phones in the room didn’t iWork and they were supposed to come and fix it but never did. Reviewed on 13 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=57057177&PinnedHotelID=57057177&HadPinnedHotel=true®ionId=553248635976008329) ![Residence Inn by Marriott St Louis Downtown](https://images.trvl-media.com/lodging/2000000/1280000/1273600/1273566/a7e6efee_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Residence Inn by Marriott St Louis Downtown 525 S Jefferson Ave St. Louis MO £101 25 Jan - 26 Jan includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a 24-hour fitness centre and parking (surcharge). Our guests praise the breakfast and the ... 7.8/10 Good! (1,000 reviews) Staff was courteous. Breakfast was great. Bedroom and bathroom were clean. Reviewed on 1 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=25%2F01%2F2026&endDate=26%2F01%2F2026&selected=1273566&PinnedHotelID=1273566&HadPinnedHotel=true®ionId=553248635976008329) ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt Regency St. Louis at The Arch 315 Chestnut St St. Louis MO Fully refundableReserve now, pay when you stay £110 17 Jan - 18 Jan includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ... 8.4/10 Very Good! (4,040 reviews) Great view Reviewed on 12 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=17%2F01%2F2026&endDate=18%2F01%2F2026&selected=14877&PinnedHotelID=14877&HadPinnedHotel=true®ionId=553248635976008329) ![Hampton Inn St. Louis-Downtown (At the Gateway Arch)](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/w3837h2560x0y0-a6354f1b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn St. Louis-Downtown (At the Gateway Arch) 333 Washington Ave St. Louis MO £85 23 Jan - 24 Jan includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ... 8.6/10 Excellent! (1,215 reviews) No, the room wasn't spotless. One of the ottomans underneath the desk has some type of white crumbs or something on it. Other than that, the hospitality was nice. Reviewed on 11 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=22520&PinnedHotelID=22520&HadPinnedHotel=true®ionId=553248635976008329) ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 421 N 8th St St. Louis MO £86 25 Jan - 26 Jan includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean ... 8.6/10 Excellent! (1,191 reviews) Wonderful stay Reviewed on 8 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=25%2F01%2F2026&endDate=26%2F01%2F2026&selected=8131949&PinnedHotelID=8131949&HadPinnedHotel=true®ionId=553248635976008329) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 21C Museum Hotel St Louis 1528 Locust street St. Louis MO £129 8 Feb - 9 Feb includes taxes & fees Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ... 9/10 Wonderful! (1,539 reviews) Good vibe Reviewed on 7 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=08%2F02%2F2026&endDate=09%2F02%2F2026&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=553248635976008329) [See all 1,835 properties in Midtown](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=16%2F01%2F2026&endDate=17%2F01%2F2026®ionId=553248635976008329) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Midtown hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=2026-01-15&endDate=2026-01-16)[15 Jan - 16 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=2026-01-15&endDate=2026-01-16) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=2026-01-16&endDate=2026-01-17)[16 Jan - 17 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=2026-01-16&endDate=2026-01-17) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=16%2F01%2F2026&endDate=18%2F01%2F2026)[16 Jan - 18 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=16%2F01%2F2026&endDate=18%2F01%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=23%2F01%2F2026&endDate=25%2F01%2F2026)[23 Jan - 25 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=23%2F01%2F2026&endDate=25%2F01%2F2026) --- ### Other neighbourhoods around Midtown ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### The Gate While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium. [](https://expedia.co.uk/St-Louis-The-Gate.dx553248635976474004) ![St. Louis showing interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21573-Saint-Louis.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown West While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station. [](https://expedia.co.uk/St-Louis-Downtown-West.dx553248635976473134) ![Lafayette Square featuring a house and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199627-Saint-Louis.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Lafayette Square The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby. [](https://expedia.co.uk/St-Louis-Lafayette-Square.dx6292381) ![Default Image](https://mediaim.expedia.com/destination/2/a89c7dead6cca8d1edf30903beaa32df.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### The Grove While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum. [](https://expedia.co.uk/St-Louis-The-Grove.dx808797266555363328) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Shaw Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out. [](https://expedia.co.uk/St-Louis-Shaw.dx553248635976473555) ![Central West End](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199931-Central-West-End.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Central West End 4.5/5(2 area reviews) If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town. [](https://expedia.co.uk/St-Louis-Central-West-End.dx6175135) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Midtown Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app