Search Hotels in Midtown, St. Louis

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Midtown hotels

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (667 reviews)
"Staff was amazing and hotel was super clean. Great locations with easy access. Valet was fast and took great care of us. "
United States
Kyle
The price is £116
includes taxes & fees
2 Mar - 3 Mar
Element St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1,002 reviews)
"All good"
United States
Christopher-Joi
The price is £96
includes taxes & fees
16 Feb - 17 Feb
Residence Inn by Marriott St Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
2.5 star property
Downtown West, 0.8 mi from Midtown
9.2 out of 10, Wonderful, (1,003 reviews)
"Breakfast was not good at all but the rooms were clean and there was easy parking"
United States
Elizabeth
The price is £97
includes taxes & fees
9 Mar - 10 Mar
Fairfield Inn & Suites by Marriott St. Louis Downtown

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
5.8 mi from Midtown
9.4 out of 10, Exceptional, (868 reviews)
"We always enjoy our stay here nice clean and great location "
United States
Dominique
The price is £106
includes taxes & fees
22 Feb - 23 Feb
Courtyard by Marriott St. Louis Brentwood

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 2.2 mi from Midtown
8.8 out of 10, Excellent, (1,218 reviews)
"friendly helpful staff, clean comfy room"
United States
Lisa
The price is £91
includes taxes & fees
16 Feb - 17 Feb
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Moonrise Hotel

Moonrise Hotel
4.0 star property
4.2 mi from Midtown
9.0 out of 10, Wonderful, (1,920 reviews)
"The staff was wonderful. Very unique hotel it was awesome."
United States
Jaden
The price is £109
includes taxes & fees
9 Mar - 10 Mar
Moonrise Hotel

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
16.8 mi from Midtown
8.4 out of 10, Very good, (1,003 reviews)
"The room was great. I enjoyed my stay. "
United States
Wanda
The price is £181
includes taxes & fees
12 Feb - 13 Feb
Ameristar Casino Resort and Spa

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis, 2 mi from Midtown
9.0 out of 10, Wonderful, (1,075 reviews)
"Very nice staff. "
United States
Sharon
The price is £81
includes taxes & fees
16 Feb - 17 Feb
Pear Tree Inn St. Louis Convention Center

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 2.1 mi from Midtown
8.8 out of 10, Excellent, (1,035 reviews)
"Always a pleasure to stay there it’s one of my favorite places in St. Louis. "
United States
Dorris
The price is £103
includes taxes & fees
16 Feb - 17 Feb
Hilton Pennywell St. Louis at the Arch

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
14.4 mi from Midtown
8.0 out of 10, Very good, (1,093 reviews)
"Great room, great people, great breakfast "
United States
Jaiden
The price is £76
includes taxes & fees
9 Feb - 10 Feb
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 2 mi from Midtown
8.8 out of 10, Excellent, (1,283 reviews)
"Clean room, great breakfast, perfect location."
United States
Kevin
The price is £102
includes taxes & fees
23 Feb - 24 Feb
Embassy Suites by Hilton St. Louis Downtown

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 2.1 mi from Midtown
8.4 out of 10, Very good, (4,018 reviews)
"Nice room & friendly staff!"
United States
Cynthia
The price is £112
includes taxes & fees
28 Feb - 1 Mar
Hyatt Regency St. Louis at The Arch

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
6.1 mi from Midtown
8.8 out of 10, Excellent, (3,086 reviews)
"The price was amazing for the great service and stay. Definitely would stay again!"
United States
Regan
The price is £89
includes taxes & fees
12 Feb - 13 Feb
Clayton Plaza Hotel & Extended Stay

Casino Queen Hotel

Casino Queen Hotel
3.0 star property
2.8 mi from Midtown
7.8 out of 10, Good, (2,008 reviews)
"Yes it was a great stay"
United States
Suzy
The price is £72
includes taxes & fees
9 Feb - 10 Feb
Casino Queen Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 1.9 mi from Midtown
8.8 out of 10, Excellent, (1,228 reviews)
"Wonderful stay"
United States
David
The price is £101
includes taxes & fees
9 Mar - 10 Mar
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
17 mi from Midtown
9.4 out of 10, Exceptional, (1,000 reviews)
"Wonderful place staff awesome "
United States
Chad
The price is £94
includes taxes & fees
15 Feb - 16 Feb
Country Inn & Suites by Radisson, St. Charles Historic District

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
4.8 mi from Midtown
9.4 out of 10, Exceptional, (474 reviews)
"Great place to stay, friendly staff, nice room, bathroom, and TV. "
United States
Natalie
The price is £129
includes taxes & fees
1 Mar - 2 Mar
The Knight Center at Washington University

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 2.1 mi from Midtown
9.4 out of 10, Exceptional, (3,326 reviews)
"Nice staff, clean rooms, dinner and breakfast for quests. "
United States
Brad
The price is £113
includes taxes & fees
12 Feb - 13 Feb
Drury Plaza Hotel St. Louis at the Arch

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
0.5 mi from Midtown
8.8 out of 10, Excellent, (1,056 reviews)
"Clean room and great staff"
United States
Chenier
The price is £103
includes taxes & fees
22 Feb - 23 Feb
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Soulard

You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, Element St. Louis Midtown is the highest ranked property in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool. Another top choice in the area is Residence Inn by Marriott St Louis Downtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks such as Washington Avenue Historic District, Scott Joplin House State Historic Site and Samuel Cupples House and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. Favourite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium and Gateway Arch. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

Explore a world of travel with Expedia