Title: Midtown Travel Guide: Best of Midtown, St. Louis Travel 2026 | Expedia.co.uk [Hotels in Midtown](https://expedia.co.uk/Midtown-Hotels.d553248635976008329.Travel-Guide-Hotels)[Flights to St. Louis](https://expedia.co.uk/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Midtown Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Midtown.d553248635976008329.Car-Hire-Guide)[Midtown Holidays](https://expedia.co.uk/Midtown.d553248635976008329.Holidays-City-Breaks) # Midtown Travel Guide ## St. Louis ![St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.](https://images.trvl-media.com/place/502875/5ca38745-4153-4e94-ab7e-09c532468b9f.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.](https://images.trvl-media.com/place/502875/5ca38745-4153-4e94-ab7e-09c532468b9f.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Midtown](https://images.trvl-media.com/place/3284/d55b436c-a6f6-420f-818f-aa3ccdc0a7fa.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Midtown](https://images.trvl-media.com/place/3284/72436d55-6453-454a-932d-0eb0c75005e5.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Midtown](https://images.trvl-media.com/place/3284/d64474b6-ef59-4458-b07b-0c0eda260efa.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Midtown Things to do Hotels Where to stay [St. Louis travel guide](https://expedia.co.uk/St-Louis.dx178309) --- ### Popular places to visit ![St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.](https://images.trvl-media.com/place/502875/5ca38745-4153-4e94-ab7e-09c532468b9f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis University Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums. [](https://expedia.co.uk/St-Louis-University-Midtown.d502875.Attraction) ![The Joplin Homestead](https://images.trvl-media.com/place/3284/356d36f9-7267-4616-a8e1-8b9b45d12e13.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Scott Joplin House State Historic Site Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game. [](https://expedia.co.uk/Scott-Joplin-House-State-Historic-Site-St-Louis.d553248621555612572.Attraction) ![Union Station, St. Louis, MO](https://images.trvl-media.com/place/502868/8704491b-9324-4c56-89ed-94a638702313.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Union Station 4.5/5(4 reviews) You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game. [](https://expedia.co.uk/St-Louis-Union-Station-St-Louis.d502868.Attraction) ![St. Louis Cardinals Baseball. ](https://images.trvl-media.com/place/3284/67189e41-0060-455b-85a9-ab65c9125a63.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Busch Stadium 2/5(1 review) Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theatre scene or attend a baseball game. [](https://expedia.co.uk/Busch-Stadium-St-Louis.d502872.Attraction) ![Gateway Arch showing a city, city views and skyline](https://images.trvl-media.com/place/502855/34e3411a-eeba-4fa1-95fe-3ad9b54938f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Gateway Arch 5/5(16 reviews) Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark. [](https://expedia.co.uk/Gateway-Arch-Downtown-St-Louis.d502855.Attraction) ![Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.](https://images.trvl-media.com/place/502873/da730472-6151-40a1-b074-013a6c50d0f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Enterprise Center Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game. [](https://expedia.co.uk/Enterprise-Center-St-Louis.d502873.Attraction) ### Things to do ![St. Louis: Gateway Ghouls and Hauntings Walking Tour](https://mediaim.expedia.com/localexpert/47668485/dd78fc5b-2837-423e-80a2-c4dfd8151a08.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Ghost Tour: Sinister Sins & Shadows £18 per adult [](https://expedia.co.uk/things-to-do/st-louis-ghost-tour-sinister-sins-shadows.a47668485.activity-details) ![Lemp Haunted Neighborhood Walking Tour](https://mediaim.expedia.com/localexpert/1357747/a0055784-5adb-4f81-8c3e-b01a05d29286.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Lemp Haunted Neighborhood Walking Tour £22 per adult **84%** of travellers recommend [](https://expedia.co.uk/things-to-do/lemp-haunted-neighborhood-walking-tour.a1357747.activity-details) ![Downtown St. Louis Smartphone Guided Audio Walking Tour App](https://mediaim.expedia.com/localexpert/49595158/04b4ccdd-3590-44c6-ae14-398df578c2e0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Downtown St. Louis Smartphone Guided Audio Walking Tour App £6 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/downtown-st-louis-smartphone-guided-audio-walking-tour-app.a49595158.activity-details) ![Step into the shadows and discover the haunting tales of our city's past.](https://mediaim.expedia.com/localexpert/5257552/b4659624-7f65-40c9-a170-6266a1de13ce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour £24 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-ghost-tours-sinister-sins-shadows-ghost-tour.a5257552.activity-details) ![Best of St. Louis Small Group Tour w/ Arch & River Cruise](https://mediaim.expedia.com/localexpert/46051486/4ca2bb68-86bc-4a3d-a7eb-e432157373a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Premium Small Group Tour With Arch & River Cruise £125 per adult **84%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-premium-small-group-tour-with-arch-river-cruise.a46051486.activity-details) ![St Louis Self-Guided Driving and Walking Audio Tour](https://mediaim.expedia.com/localexpert/49269846/95dbaecc-d0df-4a0c-a007-7dc95eddf58f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Self-Guided Driving and Walking Audio Tour £13 per traveller [](https://expedia.co.uk/things-to-do/st-louis-self-guided-driving-and-walking-audio-tour.a49269846.activity-details) [See all activities in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities) --- ## Top hotels in Midtown ![Element St. Louis Midtown](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/3e830499_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Element St. Louis Midtown 3763 Forest Park Avenue St. Louis MO £118 30 Mar - 31 Mar includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ... 9/10 Wonderful! (687 reviews) Pool was okay. Staff was attentive. Breakfast was included, but no meat. Reviewed on 9 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=30%2F03%2F2026&endDate=31%2F03%2F2026&selected=57057177&PinnedHotelID=57057177&HadPinnedHotel=true®ionId=553248635976008329) ![Residence Inn by Marriott St Louis Downtown](https://images.trvl-media.com/lodging/2000000/1280000/1273600/1273566/a7e6efee_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Residence Inn by Marriott St Louis Downtown 525 S Jefferson Ave St. Louis MO £105 30 Mar - 31 Mar includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a 24-hour fitness centre and parking (surcharge). Our guests praise the breakfast and the ... 7.8/10 Good! (1,008 reviews) Pulled out the sofa bed and stains all over. Third person (that I paid for was not able to sleep on the mattress). Took pictures showed to front desk and they took the pictures from my phone and said “ok” . Absolutely disgusting. Reviewed on 9 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=30%2F03%2F2026&endDate=31%2F03%2F2026&selected=1273566&PinnedHotelID=1273566&HadPinnedHotel=true®ionId=553248635976008329) ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/5c61cbf8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clayton Plaza Hotel & Extended Stay 7750 Carondelet Avenue St. Louis MO Fully refundableReserve now, pay when you stay £91 29 Mar - 30 Mar includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ... 8.8/10 Excellent! (3,123 reviews) The water pressure in our room's shower was the worst I've ever experienced. Reviewed on 9 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=29%2F03%2F2026&endDate=30%2F03%2F2026&selected=18144&PinnedHotelID=18144&HadPinnedHotel=true®ionId=553248635976008329) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bd7064dc_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 21C Museum Hotel St Louis 1528 Locust street St. Louis MO £114 5 Apr - 6 Apr includes taxes & fees Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ... 9/10 Wonderful! (1,646 reviews) Stay was great and the hotel was a close walk to Enterprise Center. Reviewed on 9 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=553248635976008329) ![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/e43b9580_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel St. Louis at the Arch 2 South 4th Street St. Louis MO £118 15 Mar - 16 Mar includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ... 9.4/10 Exceptional! (3,360 reviews) National park near, friendlty & welcoming staff, great accommodations, wonderful food & cheers, all star view from 8th floor balcony Reviewed on 9 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=15%2F03%2F2026&endDate=16%2F03%2F2026&selected=546271&PinnedHotelID=546271&HadPinnedHotel=true®ionId=553248635976008329) ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/ad35f056_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt Regency St. Louis at The Arch 315 Chestnut St St. Louis MO £149 23 Mar - 24 Mar includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ... 8.6/10 Excellent! (4,008 reviews) The hotel was great. I love the options to dine at the hotel. The brewery had amazing food with great staff and the breakfast buffet was wonderful. The front staff were all polite and friendly. The hotel store was open early and late which was very convenient. The area was also pleasant and had a ... Reviewed on 9 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=23%2F03%2F2026&endDate=24%2F03%2F2026&selected=14877&PinnedHotelID=14877&HadPinnedHotel=true®ionId=553248635976008329) [See all 1,884 properties in Midtown](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=10%2F03%2F2026&endDate=11%2F03%2F2026®ionId=553248635976008329) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=DX-NH_SPRING_PROMO_553248635976008329) ## Check Midtown hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=2026-03-09&endDate=2026-03-10)[9 Mar - 10 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=2026-03-09&endDate=2026-03-10) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=2026-03-10&endDate=2026-03-11)[10 Mar - 11 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=2026-03-10&endDate=2026-03-11) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=13%2F03%2F2026&endDate=15%2F03%2F2026)[13 Mar - 15 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=13%2F03%2F2026&endDate=15%2F03%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=20%2F03%2F2026&endDate=22%2F03%2F2026)[20 Mar - 22 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976008329&startDate=20%2F03%2F2026&endDate=22%2F03%2F2026) --- ### Other neighbourhoods around Midtown ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### The Gate While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium. [](https://expedia.co.uk/St-Louis-The-Gate.dx553248635976474004) ![Love this hotel.](https://images.trvl-media.com/place/3284/7d953ffd-a093-422e-8101-35af3b9eb6fc.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown West While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station. [](https://expedia.co.uk/St-Louis-Downtown-West.dx553248635976473134) ![Lafayette Square featuring a house and a park](https://images.trvl-media.com/place/6292381/f746e8db-cb81-4d52-a7d7-3ec56595e9b0.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Lafayette Square The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby. [](https://expedia.co.uk/St-Louis-Lafayette-Square.dx6292381) ![Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia](https://images.trvl-media.com/place/3284/4b636840-fa59-4f14-a526-b5e40380bb6b.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### The Grove While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum. [](https://expedia.co.uk/St-Louis-The-Grove.dx808797266555363328) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Shaw Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out. [](https://expedia.co.uk/St-Louis-Shaw.dx553248635976473555) ![Central West End](https://images.trvl-media.com/place/6175135/a1a4060c-5623-4543-941c-91e3f85f02cc.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Central West End 4.5/5(2 area reviews) If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town. [](https://expedia.co.uk/St-Louis-Central-West-End.dx6175135) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Midtown Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app