Title: Downtown Clayton Travel Guide: Best of Downtown Clayton, St. Louis Travel 2026 | Expedia.co.uk [Hotels in Downtown Clayton](https://expedia.co.uk/Downtown-Clayton-St-Louis-Hotels.0-n553248635976477194-0.Travel-Guide-Filter-Hotels)[Flights to St. Louis](https://expedia.co.uk/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Downtown Clayton Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Downtown-Clayton.d553248635976477194.Car-Hire-Guide)[Downtown Clayton Holidays](https://expedia.co.uk/Downtown-Clayton.d553248635976477194.Holidays-City-Breaks) # Downtown Clayton Travel Guide ## St. Louis ![The fire department bell](https://images.trvl-media.com/place/6058846/cbde4fed-6065-460d-be7e-6bd63ab3fcff.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The fire department bell](https://images.trvl-media.com/place/6058846/cbde4fed-6065-460d-be7e-6bd63ab3fcff.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Downtown Clayton Things to do Hotels Where to stay [St. Louis travel guide](https://expedia.co.uk/St-Louis.dx178309) --- ### Popular places to visit ![Union Station, St. Louis, MO](https://images.trvl-media.com/place/502868/8704491b-9324-4c56-89ed-94a638702313.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Union Station 4.5/5(4 reviews) You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game. [](https://expedia.co.uk/St-Louis-Union-Station-St-Louis.d502868.Attraction) ![St. Louis Cardinals Baseball. ](https://images.trvl-media.com/place/3284/67189e41-0060-455b-85a9-ab65c9125a63.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Busch Stadium 2/5(1 review) Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game. [](https://expedia.co.uk/Busch-Stadium-St-Louis.d502872.Attraction) ![Gateway Arch showing a city, city views and skyline](https://images.trvl-media.com/place/502855/34e3411a-eeba-4fa1-95fe-3ad9b54938f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Gateway Arch 5/5(16 reviews) Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark. [](https://expedia.co.uk/Gateway-Arch-Downtown-St-Louis.d502855.Attraction) ![Saint Louis is a City and Urban Center is Missouri with the Iconic Arch](https://images.trvl-media.com/place/6058090/0265bc5b-4681-44d3-90f6-25e6868a0534.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Dome at America’s Center 5/5(4 reviews) Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and great live music. [](https://expedia.co.uk/Dome-At-Americas-Center-Downtown-St-Louis.d6058090.Attraction) ![St. Louis Zoo](https://images.trvl-media.com/place/502878/51adfd0a-5175-4aa9-aa40-2221835ea3ae.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Zoo In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world. [](https://expedia.co.uk/St-Louis-Zoo-St-Louis.d502878.Attraction) ![Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.](https://images.trvl-media.com/place/502873/da730472-6151-40a1-b074-013a6c50d0f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Enterprise Center Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game. [](https://expedia.co.uk/Enterprise-Center-St-Louis.d502873.Attraction) ### Things to do ![St. Louis: Gateway Ghouls and Hauntings Walking Tour](https://mediaim.expedia.com/localexpert/47668485/dd78fc5b-2837-423e-80a2-c4dfd8151a08.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Ghost Tour: Sinister Sins & Shadows £23 per adult [](https://expedia.co.uk/things-to-do/st-louis-ghost-tour-sinister-sins-shadows.a47668485.activity-details) ![Downtown St. Louis Smartphone Guided Audio Walking Tour App](https://mediaim.expedia.com/localexpert/49595158/04b4ccdd-3590-44c6-ae14-398df578c2e0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Downtown St. Louis Smartphone Guided Audio Walking Tour App £6 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/downtown-st-louis-smartphone-guided-audio-walking-tour-app.a49595158.activity-details) ![Step into the shadows and discover the haunting tales of our city's past.](https://mediaim.expedia.com/localexpert/5257552/b4659624-7f65-40c9-a170-6266a1de13ce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour £23 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-ghost-tours-sinister-sins-shadows-ghost-tour.a5257552.activity-details) ![Best of St. Louis Small Group Tour w/ Arch & River Cruise](https://mediaim.expedia.com/localexpert/46051486/4ca2bb68-86bc-4a3d-a7eb-e432157373a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Premium Small Group Tour With Arch & River Cruise £123 per adult **84%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-premium-small-group-tour-with-arch-river-cruise.a46051486.activity-details) ![St Louis Self-Guided Driving and Walking Audio Tour](https://mediaim.expedia.com/localexpert/49269846/95dbaecc-d0df-4a0c-a007-7dc95eddf58f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Self-Guided Driving and Walking Audio Tour £12 per traveller [](https://expedia.co.uk/things-to-do/st-louis-self-guided-driving-and-walking-audio-tour.a49269846.activity-details) ![St. Louis Premium Driving Tour with Boat Ride & Arch](https://mediaim.expedia.com/localexpert/47712556/5e48de69-a78b-4315-bccd-6ae9dafd98a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Premium Driving Tour with Boat Ride & Arch £127 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-premium-driving-tour-with-boat-ride-arch.a47712556.activity-details) [See all activities in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities) --- ## Top hotels in Downtown Clayton ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clayton Plaza Hotel & Extended Stay 7750 Carondelet Avenue St. Louis MO £90 28 Feb - 1 Mar includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ... 8.8/10 Excellent! (3,089 reviews) Only place I will stay in st louis- clean, nice facility, pleasant staff Reviewed on 8 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=28%2F02%2F2026&endDate=01%2F03%2F2026&selected=18144&PinnedHotelID=18144&HadPinnedHotel=true®ionId=553248635976477194) ![The Ritz-Carlton, St. Louis](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/9a597e77_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Ritz-Carlton, St. Louis 100 Carondelet Plaza St. Louis MO £427 15 Mar - 16 Mar includes taxes & fees Stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff and the room service ... 9.2/10 Wonderful! (557 reviews) Excellent hotel with various restaurants and expansive lobby area.. staff very attentive. Reviewed on 6 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=15%2F03%2F2026&endDate=16%2F03%2F2026&selected=6132&PinnedHotelID=6132&HadPinnedHotel=true®ionId=553248635976477194) ![Le Méridien St. Louis Clayton](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/b428f8e9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Le Méridien St. Louis Clayton 7730 Bonhomme Ave St. Louis MO £117 22 Feb - 23 Feb includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ... 8.8/10 Excellent! (692 reviews) Room was beautiful and clean. Reviewed on 2 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=3072&PinnedHotelID=3072&HadPinnedHotel=true®ionId=553248635976477194) ![AC Hotel St. Louis Clayton](https://images.trvl-media.com/lodging/106000000/105380000/105374500/105374473/4a44ac13_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### AC Hotel St. Louis Clayton 227 South Central Ave St. Louis MO £111 22 Feb - 23 Feb includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park are ... 9/10 Wonderful! (243 reviews) My room was spotless and very well put together. Reviewed on 9 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=105374473&PinnedHotelID=105374473&HadPinnedHotel=true®ionId=553248635976477194) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 21C Museum Hotel St Louis 1528 Locust street St. Louis MO £119 22 Feb - 23 Feb includes taxes & fees Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ... 9/10 Wonderful! (1,599 reviews) We loved this hotel. It is something you expect in much more sophisticated cities but not St. Louis. Our king bed suite was tastefully furnished and very large. Lots of great touches and very clean. The lobby and museum were stylish and exciting. We ate at both Idolwolf and the cafe. Again great ... Reviewed on 8 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=553248635976477194) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Pear Tree Inn St. Louis Airport 10810 Pear Tree Ln St. Ann MO £77 18 Feb - 19 Feb includes taxes & fees Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ... 9.2/10 Wonderful! (2,813 reviews) Great experience Reviewed on 11 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=18%2F02%2F2026&endDate=19%2F02%2F2026&selected=1096579&PinnedHotelID=1096579&HadPinnedHotel=true®ionId=553248635976477194) [See all 1,829 properties in Downtown Clayton](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=13%2F02%2F2026&endDate=14%2F02%2F2026®ionId=553248635976477194) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=DX-NH_SPRING_PROMO_553248635976477194) ## Check Downtown Clayton hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976477194&startDate=2026-02-12&endDate=2026-02-13)[12 Feb - 13 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976477194&startDate=2026-02-12&endDate=2026-02-13) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976477194&startDate=2026-02-13&endDate=2026-02-14)[13 Feb - 14 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976477194&startDate=2026-02-13&endDate=2026-02-14) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976477194&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976477194&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976477194&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026)[20 Feb - 22 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976477194&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026) --- ### Other neighbourhoods around Downtown Clayton ![St. Louis Missouri](https://images.trvl-media.com/place/6058846/ad61b28c-fc90-4997-9e8c-7d09999a125f.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Clayton Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city. [](https://expedia.co.uk/St-Louis-Clayton.dx6058846) ![New Loop Trolley at Delmar St Louis](https://images.trvl-media.com/place/168530/8f68dfd9-a2c8-488e-9057-b1d69fba3d6c.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### University City Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city. [](https://expedia.co.uk/St-Louis-University-City.dx168530) ![View of St. Louis and the historic Gateway Arch in Missouri, from across the Mississippi River in Malcolm W. Martin Memorial Park, Illinois](https://images.trvl-media.com/place/3000445131/3bcf72ac-0b8e-4793-b806-c2095dbd57ef.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Ladue Ladue is well liked for its restaurants and churches. If you're hoping to see more of the larger area, Saint Louis Galleria Mall and St. Louis Art Museum are some interesting sights nearby to check out. [](https://expedia.co.uk/St-Louis-Ladue.dx3000445131) ![The bandstand located in Forest Park, St. Louis, Missouri.](https://images.trvl-media.com/place/869720623190908928/ea83bdbb-8bbe-4f43-bdf9-2be351a3f638.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Dogtown When in Dogtown, you can plan a visit to St. Louis Zoo and St. Louis Art Museum, some noteworthy sights in the nearby area. [](https://expedia.co.uk/St-Louis-Dogtown.dx869720623190908928) ![Visitor Center in Forest Park in St. Louis](https://images.trvl-media.com/place/553248635976385822/e360c28d-4d90-46fd-89e2-0e68b4c73e0b.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### The Hill While The Hill isn't home to many top sights, St. Louis Science Center and Missouri Botanical Gardens and Arboretum are some notable places to visit nearby. [](https://expedia.co.uk/St-Louis-The-Hill.dx553248635976385822) ![Central West End](https://images.trvl-media.com/place/6175135/a1a4060c-5623-4543-941c-91e3f85f02cc.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Central West End 4.5/5(2 area reviews) If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town. [](https://expedia.co.uk/St-Louis-Central-West-End.dx6175135) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Downtown Clayton Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app