Title: Clayton Travel Guide: Best of Clayton, St. Louis Travel 2026 | Expedia.co.uk [Hotels in Clayton](https://expedia.co.uk/Clayton-St-Louis-Hotels.0-n6058846-0.Travel-Guide-Filter-Hotels)[Flights to St. Louis](https://expedia.co.uk/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Clayton Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Clayton.d6058846.Car-Hire-Guide)[Clayton Holidays](https://expedia.co.uk/Clayton.d6058846.Holidays-City-Breaks) # Clayton Travel Guide ## St. Louis ![St. Louis Missouri](https://images.trvl-media.com/place/6058846/ad61b28c-fc90-4997-9e8c-7d09999a125f.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![City of St. Louis](https://images.trvl-media.com/place/6058846/d3a401eb-af67-4fd3-b03e-61abc3c96f73.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![St. Louis, Missouri, USA Downtown Cityscape on the River](https://images.trvl-media.com/place/6058846/28eb9b2a-a66f-45d3-b9ff-5da585f43771.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![St. Louis, Missouri - 08.22.2021 - Ridgley Hall and the Brookings Quad on the Danforth Campus of Washington University in St. Louis.](https://images.trvl-media.com/place/6058846/041cab77-e736-4cae-a6ec-daee656ebc16.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![View over the Post-Dispatch Lake riffles at Forest Park (St. Louis) on a beautiful summer day.](https://images.trvl-media.com/place/6058846/02520534-93e7-47df-b9bd-5119e667dd2e.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Clayton Things to do Hotels Where to stay [St. Louis travel guide](https://expedia.co.uk/St-Louis.dx178309) --- ### Popular places to visit ![St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.](https://images.trvl-media.com/place/502876/30a14638-e6de-4f99-9bb4-fcc8ce569bb3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Washington University in St. Louis Explore the campus of Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event. [](https://expedia.co.uk/Washington-University-In-St-Louis-St-Louis.d502876.Attraction) ![Union Station, St. Louis, MO](https://images.trvl-media.com/place/502868/8704491b-9324-4c56-89ed-94a638702313.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Union Station 4.5/5(4 reviews) You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game. [](https://expedia.co.uk/St-Louis-Union-Station-St-Louis.d502868.Attraction) ![St. Louis Cardinals Baseball. ](https://images.trvl-media.com/place/3284/67189e41-0060-455b-85a9-ab65c9125a63.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Busch Stadium 2/5(1 review) Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theatre scene or attend a baseball game. [](https://expedia.co.uk/Busch-Stadium-St-Louis.d502872.Attraction) ![Gateway Arch showing a city, city views and skyline](https://images.trvl-media.com/place/502855/34e3411a-eeba-4fa1-95fe-3ad9b54938f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Gateway Arch 5/5(16 reviews) Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark. [](https://expedia.co.uk/Gateway-Arch-Downtown-St-Louis.d502855.Attraction) ![Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.](https://images.trvl-media.com/place/502873/da730472-6151-40a1-b074-013a6c50d0f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Enterprise Center Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game. [](https://expedia.co.uk/Enterprise-Center-St-Louis.d502873.Attraction) ![St. Louis Zoo](https://images.trvl-media.com/place/502878/51adfd0a-5175-4aa9-aa40-2221835ea3ae.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Zoo In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world. [](https://expedia.co.uk/St-Louis-Zoo-St-Louis.d502878.Attraction) ### Things to do ![St. Louis: Gateway Ghouls and Hauntings Walking Tour](https://mediaim.expedia.com/localexpert/47668485/dd78fc5b-2837-423e-80a2-c4dfd8151a08.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Ghost Tour: Sinister Sins & Shadows £18 per adult [](https://expedia.co.uk/things-to-do/st-louis-ghost-tour-sinister-sins-shadows.a47668485.activity-details) ![Lemp Haunted Neighborhood Walking Tour](https://mediaim.expedia.com/localexpert/1357747/a0055784-5adb-4f81-8c3e-b01a05d29286.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Lemp Haunted Neighborhood Walking Tour £22 per adult **84%** of travellers recommend [](https://expedia.co.uk/things-to-do/lemp-haunted-neighborhood-walking-tour.a1357747.activity-details) ![Downtown St. Louis Smartphone Guided Audio Walking Tour App](https://mediaim.expedia.com/localexpert/49595158/04b4ccdd-3590-44c6-ae14-398df578c2e0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Downtown St. Louis Smartphone Guided Audio Walking Tour App £6 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/downtown-st-louis-smartphone-guided-audio-walking-tour-app.a49595158.activity-details) ![Best of St. Louis Small Group Tour w/ Arch & River Cruise](https://mediaim.expedia.com/localexpert/46051486/4ca2bb68-86bc-4a3d-a7eb-e432157373a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Premium Small Group Tour With Arch & River Cruise £125 per adult **84%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-premium-small-group-tour-with-arch-river-cruise.a46051486.activity-details) ![Step into the shadows and discover the haunting tales of our city's past.](https://mediaim.expedia.com/localexpert/5257552/b4659624-7f65-40c9-a170-6266a1de13ce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour £24 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-ghost-tours-sinister-sins-shadows-ghost-tour.a5257552.activity-details) ![St Louis Self-Guided Driving and Walking Audio Tour](https://mediaim.expedia.com/localexpert/49269846/95dbaecc-d0df-4a0c-a007-7dc95eddf58f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Self-Guided Driving and Walking Audio Tour £13 per traveller [](https://expedia.co.uk/things-to-do/st-louis-self-guided-driving-and-walking-audio-tour.a49269846.activity-details) [See all activities in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities) --- ## Top hotels in Clayton ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/5c61cbf8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clayton Plaza Hotel & Extended Stay 7750 Carondelet Avenue St. Louis MO £87 5 Apr - 6 Apr includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ... 8.8/10 Excellent! (3,129 reviews) Stay was wonderful. Would definitely recommend. Reviewed on 23 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=18144&PinnedHotelID=18144&HadPinnedHotel=true®ionId=6058846) ![The Ritz-Carlton, St. Louis](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/a54897ef_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Ritz-Carlton, St. Louis 100 Carondelet Plaza St. Louis MO £434 29 Mar - 30 Mar includes taxes & fees Stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff and the room service ... 9.2/10 Wonderful! (561 reviews) Property needs remodeling Reviewed on 24 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=29%2F03%2F2026&endDate=30%2F03%2F2026&selected=6132&PinnedHotelID=6132&HadPinnedHotel=true®ionId=6058846) ![Hampton Inn & Suites Clayton/St. Louis-Galleria Area](https://images.trvl-media.com/lodging/1000000/20000/17600/17599/ff4ffddd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn & Suites Clayton/St. Louis-Galleria Area 216 N Meramec Ave St. Louis MO £100 12 Apr - 13 Apr includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness centre and parking (surcharge). Our guests praise the helpful staff in their ... 9/10 Wonderful! (947 reviews) Staff was wonderful, and the hotel in general was great. However, I was surprised to find no parking spots open on the premises after I had paid for parking. I was told I would receive a refund and I’m sure I will. As for the room, it was very tidy, clean, and well organized. Upon waking up on the ... Reviewed on 15 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=12%2F04%2F2026&endDate=13%2F04%2F2026&selected=17599&PinnedHotelID=17599&HadPinnedHotel=true®ionId=6058846) ![Le Méridien St. Louis Clayton](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/295bf6e6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Le Méridien St. Louis Clayton 7730 Bonhomme Ave St. Louis MO £119 5 Apr - 6 Apr includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ... 8.8/10 Excellent! (701 reviews) For the price of this hotel, I was incredibly disappointed in both our room as well as the staff. Our room was not very clean when we arrived, and there were stains on the sheets. We had a two night stay and expected our room to be cleaned the next day. Nobody had visited our room at all. Honestly ... Reviewed on 22 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=3072&PinnedHotelID=3072&HadPinnedHotel=true®ionId=6058846) ![AC Hotel St. Louis Clayton](https://images.trvl-media.com/lodging/106000000/105380000/105374500/105374473/837b161d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### AC Hotel St. Louis Clayton 227 South Central Ave St. Louis MO £117 5 Apr - 6 Apr includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park are ... 9/10 Wonderful! (255 reviews) Great location Reviewed on 23 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=105374473&PinnedHotelID=105374473&HadPinnedHotel=true®ionId=6058846) ![Homewood Suites by Hilton St Louis - Galleria](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665070/f138cb25_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Homewood Suites by Hilton St Louis - Galleria 8040 Clayton Road Richmond Heights MO £113 5 Apr - 6 Apr includes taxes & fees Stay at this business-friendly hotel in Richmond Heights. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the helpful staff ... 7.8/10 Good! (1,004 reviews) pool was great staff outstanding Reviewed on 23 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=2665070&PinnedHotelID=2665070&HadPinnedHotel=true®ionId=6058846) [See all 1,891 properties in Clayton](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=25%2F03%2F2026&endDate=26%2F03%2F2026®ionId=6058846) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Clayton hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=2026-03-24&endDate=2026-03-25)[24 Mar - 25 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=2026-03-24&endDate=2026-03-25) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=2026-03-25&endDate=2026-03-26)[25 Mar - 26 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=2026-03-25&endDate=2026-03-26) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026)[27 Mar - 29 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[3 Apr - 5 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026) --- ### Other neighbourhoods around Clayton ![New Loop Trolley at Delmar St Louis](https://images.trvl-media.com/place/168530/8f68dfd9-a2c8-488e-9057-b1d69fba3d6c.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### University City Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city. [](https://expedia.co.uk/St-Louis-University-City.dx168530) ![The bandstand located in Forest Park, St. Louis, Missouri.](https://images.trvl-media.com/place/869720623190908928/ea83bdbb-8bbe-4f43-bdf9-2be351a3f638.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Dogtown When in Dogtown, you can plan a visit to St. Louis Zoo and St. Louis Art Museum, some noteworthy sights in the nearby area. [](https://expedia.co.uk/St-Louis-Dogtown.dx869720623190908928) ![View of St. Louis and the historic Gateway Arch in Missouri, from across the Mississippi River in Malcolm W. Martin Memorial Park, Illinois](https://images.trvl-media.com/place/3000445131/3bcf72ac-0b8e-4793-b806-c2095dbd57ef.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Ladue Ladue is well liked for its restaurants and churches. If you're hoping to see more of the larger area, Saint Louis Galleria Mall and St. Louis Art Museum are some interesting sights nearby to check out. [](https://expedia.co.uk/St-Louis-Ladue.dx3000445131) ![Visitor Center in Forest Park in St. Louis](https://images.trvl-media.com/place/553248635976385822/e360c28d-4d90-46fd-89e2-0e68b4c73e0b.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### The Hill While The Hill isn't home to many top sights, St. Louis Science Center and Missouri Botanical Gardens and Arboretum are some notable places to visit nearby. [](https://expedia.co.uk/St-Louis-The-Hill.dx553248635976385822) ![Southwest Garden](https://images.trvl-media.com/place/3284/d5ee2cb5-3efa-45b0-84a7-305e83948293.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Southwest Garden While Southwest Garden may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Missouri Botanical Gardens and Arboretum and St. Louis Science Center. [](https://expedia.co.uk/St-Louis-Southwest-Garden.dx553248635976471611) ![Central West End](https://images.trvl-media.com/place/6175135/a1a4060c-5623-4543-941c-91e3f85f02cc.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Central West End 4.5/5(2 area reviews) If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town. [](https://expedia.co.uk/St-Louis-Central-West-End.dx6175135) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Clayton Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app