Title: Clayton Travel Guide: Best of Clayton, St. Louis Travel 2026 | Expedia.co.uk [Hotels in Clayton](https://expedia.co.uk/Clayton-St-Louis-Hotels.0-n6058846-0.Travel-Guide-Filter-Hotels)[Flights to St. Louis](https://expedia.co.uk/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Clayton Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Clayton.d6058846.Car-Hire-Guide)[Clayton Holidays](https://expedia.co.uk/Clayton.d6058846.Holidays-City-Breaks) # Clayton Travel Guide ## St. Louis ![St. Louis Missouri](https://images.trvl-media.com/place/6058846/ad61b28c-fc90-4997-9e8c-7d09999a125f.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![St. Louis Missouri](https://images.trvl-media.com/place/6058846/ad61b28c-fc90-4997-9e8c-7d09999a125f.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![View over the Post-Dispatch Lake riffles at Forest Park (St. Louis) on a beautiful summer day.](https://images.trvl-media.com/place/6058846/02520534-93e7-47df-b9bd-5119e667dd2e.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The fire department bell](https://images.trvl-media.com/place/6058846/cbde4fed-6065-460d-be7e-6bd63ab3fcff.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Clayton Things to do Hotels Where to stay [St. Louis travel guide](https://expedia.co.uk/St-Louis.dx178309) --- ### Popular places to visit ![St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.](https://images.trvl-media.com/place/502876/30a14638-e6de-4f99-9bb4-fcc8ce569bb3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Washington University in St. Louis Explore the campus of Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event. [](https://expedia.co.uk/Washington-University-In-St-Louis-St-Louis.d502876.Attraction) ![Union Station, St. Louis, MO](https://images.trvl-media.com/place/502868/8704491b-9324-4c56-89ed-94a638702313.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Union Station You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's acclaimed art galleries or attend a baseball game. [](https://expedia.co.uk/St-Louis-Union-Station-St-Louis.d502868.Attraction) ![St. Louis Cardinals Baseball. ](https://images.trvl-media.com/place/3284/67189e41-0060-455b-85a9-ab65c9125a63.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Busch Stadium Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game. [](https://expedia.co.uk/Busch-Stadium-St-Louis.d502872.Attraction) ![Gateway Arch showing a city, city views and skyline](https://images.trvl-media.com/place/502855/34e3411a-eeba-4fa1-95fe-3ad9b54938f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Gateway Arch Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark. [](https://expedia.co.uk/Gateway-Arch-Downtown-St-Louis.d502855.Attraction) ![St. Louis Zoo](https://images.trvl-media.com/place/502878/51adfd0a-5175-4aa9-aa40-2221835ea3ae.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Zoo In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world. [](https://expedia.co.uk/St-Louis-Zoo-St-Louis.d502878.Attraction) ![Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.](https://images.trvl-media.com/place/502873/da730472-6151-40a1-b074-013a6c50d0f4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Enterprise Center Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed theatre scene or attend a baseball game. [](https://expedia.co.uk/Enterprise-Center-St-Louis.d502873.Attraction) ### Things to do ![St. Louis: Gateway Ghouls and Hauntings Walking Tour](https://mediaim.expedia.com/localexpert/47668485/dd78fc5b-2837-423e-80a2-c4dfd8151a08.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Ghost Tour: Sinister Sins & Shadows £24 per adult [](https://expedia.co.uk/things-to-do/st-louis-ghost-tour-sinister-sins-shadows.a47668485.activity-details) ![Downtown St. Louis Smartphone Guided Audio Walking Tour App](https://mediaim.expedia.com/localexpert/49595158/04b4ccdd-3590-44c6-ae14-398df578c2e0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Downtown St. Louis Smartphone Guided Audio Walking Tour App £6 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/downtown-st-louis-smartphone-guided-audio-walking-tour-app.a49595158.activity-details) ![Step into the shadows and discover the haunting tales of our city's past.](https://mediaim.expedia.com/localexpert/5257552/b4659624-7f65-40c9-a170-6266a1de13ce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour £22 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-ghost-tours-sinister-sins-shadows-ghost-tour.a5257552.activity-details) ![Best of St. Louis Small Group Tour w/ Arch & River Cruise](https://mediaim.expedia.com/localexpert/46051486/4ca2bb68-86bc-4a3d-a7eb-e432157373a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Best of St. Louis Small Group Tour w/ Arch & River Cruise £126 per adult **84%** of travellers recommend [](https://expedia.co.uk/things-to-do/best-of-st-louis-small-group-tour-w-arch-river-cruise.a46051486.activity-details) ![St Louis Self-Guided Driving and Walking Audio Tour](https://mediaim.expedia.com/localexpert/49269846/95dbaecc-d0df-4a0c-a007-7dc95eddf58f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St Louis Self-Guided Driving and Walking Audio Tour £13 per traveller [](https://expedia.co.uk/things-to-do/st-louis-self-guided-driving-and-walking-audio-tour.a49269846.activity-details) ![St. Louis Premium Driving Tour with Boat Ride & Arch](https://mediaim.expedia.com/localexpert/47712556/5e48de69-a78b-4315-bccd-6ae9dafd98a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Premium Driving Tour with Boat Ride & Arch £130 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/st-louis-premium-driving-tour-with-boat-ride-arch.a47712556.activity-details) [See all activities in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities) --- ## Top hotels in Clayton ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clayton Plaza Hotel & Extended Stay 7750 Carondelet Avenue St. Louis MO £84 8 Feb - 9 Feb includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ... 8.8/10 Excellent! (3,084 reviews) Staff always pleasant Reviewed on 2 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=08%2F02%2F2026&endDate=09%2F02%2F2026&selected=18144&PinnedHotelID=18144&HadPinnedHotel=true®ionId=6058846) ![The Ritz-Carlton, St. Louis](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/9a597e77_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Ritz-Carlton, St. Louis 100 Carondelet Plaza St. Louis MO £428 8 Mar - 9 Mar includes taxes & fees Stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff and the room service ... 9.2/10 Wonderful! (556 reviews) Very courteo Reviewed on 13 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=6132&PinnedHotelID=6132&HadPinnedHotel=true®ionId=6058846) ![Hampton Inn & Suites Clayton/St. Louis-Galleria Area](https://images.trvl-media.com/lodging/1000000/20000/17600/17599/ff4ffddd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn & Suites Clayton/St. Louis-Galleria Area 216 N Meramec Ave St. Louis MO £103 26 Feb - 27 Feb includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the helpful staff in their reviews. ... 8.8/10 Excellent! (934 reviews) Pleasant and professional staff. Updated property and was incredibly clean! Reviewed on 29 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=26%2F02%2F2026&endDate=27%2F02%2F2026&selected=17599&PinnedHotelID=17599&HadPinnedHotel=true®ionId=6058846) ![AC Hotel St. Louis Clayton](https://images.trvl-media.com/lodging/106000000/105380000/105374500/105374473/4a44ac13_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### AC Hotel St. Louis Clayton 227 South Central Ave St. Louis MO £120 22 Feb - 23 Feb includes taxes & fees Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park are ... 9/10 Wonderful! (241 reviews) My room was spotless and very well put together. Reviewed on 9 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=105374473&PinnedHotelID=105374473&HadPinnedHotel=true®ionId=6058846) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 21C Museum Hotel St Louis 1528 Locust street St. Louis MO £119 22 Feb - 23 Feb includes taxes & fees Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ... 9/10 Wonderful! (1,592 reviews) Hotel was very quiet and staff helpful and courteous. The coffee shop was great for coffee and breakfast and the rooms were clean with hot water and great water pressure. The only thing I would change was the mattress - bed was very firm, kind of felt like lying on a table. Gallery was a fun feature ... Reviewed on 3 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=6058846) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Pear Tree Inn St. Louis Airport 10810 Pear Tree Ln St. Ann MO £78 12 Feb - 13 Feb includes taxes & fees Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ... 9.2/10 Wonderful! (2,808 reviews) Staff was incredibly kind and helpful. They sent a shuttle to pick me up at the car rental place! The room was clean, the beds were comfortable, and the breakfast buffet had great options, even for our gluten-free family member. Reviewed on 5 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=12%2F02%2F2026&endDate=13%2F02%2F2026&selected=1096579&PinnedHotelID=1096579&HadPinnedHotel=true®ionId=6058846) [See all 1,856 properties in Clayton](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=6058846) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Clayton hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=2026-02-07&endDate=2026-02-08)[7 Feb - 8 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=2026-02-07&endDate=2026-02-08) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=2026-02-08&endDate=2026-02-09)[8 Feb - 9 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=2026-02-08&endDate=2026-02-09) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058846&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) --- ### Other neighbourhoods around Clayton ![New Loop Trolley at Delmar St Louis](https://images.trvl-media.com/place/168530/8f68dfd9-a2c8-488e-9057-b1d69fba3d6c.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### University City Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city. [](https://expedia.co.uk/St-Louis-University-City.dx168530) ![The bandstand located in Forest Park, St. Louis, Missouri.](https://images.trvl-media.com/place/869720623190908928/ea83bdbb-8bbe-4f43-bdf9-2be351a3f638.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Dogtown When in Dogtown, you can plan a visit to St. Louis Zoo and St. Louis Art Museum, some noteworthy sights in the nearby area. [](https://expedia.co.uk/St-Louis-Dogtown.dx869720623190908928) ![View of St. Louis and the historic Gateway Arch in Missouri, from across the Mississippi River in Malcolm W. Martin Memorial Park, Illinois](https://images.trvl-media.com/place/3000445131/3bcf72ac-0b8e-4793-b806-c2095dbd57ef.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Ladue Ladue is well liked for its restaurants and churches. If you're hoping to see more of the larger area, Saint Louis Galleria Mall and St. Louis Art Museum are some interesting sights nearby to check out. [](https://expedia.co.uk/St-Louis-Ladue.dx3000445131) ![Visitor Center in Forest Park in St. Louis](https://images.trvl-media.com/place/553248635976385822/e360c28d-4d90-46fd-89e2-0e68b4c73e0b.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### The Hill While The Hill isn't home to many top sights, St. Louis Science Center and Missouri Botanical Gardens and Arboretum are some notable places to visit nearby. [](https://expedia.co.uk/St-Louis-The-Hill.dx553248635976385822) ![Southwest Garden](https://images.trvl-media.com/place/3284/d5ee2cb5-3efa-45b0-84a7-305e83948293.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Southwest Garden While Southwest Garden may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Missouri Botanical Gardens and Arboretum and St. Louis Science Center. [](https://expedia.co.uk/St-Louis-Southwest-Garden.dx553248635976471611) ![Central West End](https://images.trvl-media.com/place/6175135/a1a4060c-5623-4543-941c-91e3f85f02cc.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Central West End 4.5/5(2 area reviews) If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town. [](https://expedia.co.uk/St-Louis-Central-West-End.dx6175135) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Clayton Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app