Title: Hotels in St. Charles, MN - Best St. Charles Hotels from £52 - Fully Refundable Options - Expedia.co.uk

[Holiday Rentals in St. Charles](https://expedia.co.uk/St-Charles-Holiday-Rentals.d183431.Travel-Guide-HolidayRentals)[St. Charles Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-St-Charles.d183431.Car-Hire-Guide)[St. Charles Holidays](https://expedia.co.uk/St-Charles.d183431.Holidays-City-Breaks)

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## Go beyond your typical stay in St. Charles

Pool

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America&regionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-01-28&d1=2026-01-28&endDate=2026-01-30&d2=2026-01-30&amenities=POOL)

Pet friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America&regionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-01-28&d1=2026-01-28&endDate=2026-01-30&d2=2026-01-30&amenities=PETS)

Hot tub

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America&regionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-01-28&d1=2026-01-28&endDate=2026-01-30&d2=2026-01-30&amenities=HOT_TUB)

Cabin

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America&regionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-01-28&d1=2026-01-28&endDate=2026-01-30&d2=2026-01-30&lodging=CABIN)

Family friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America&regionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-01-28&d1=2026-01-28&endDate=2026-01-30&d2=2026-01-30&travelerType=family_friendly)

Apart­ment

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America&regionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-01-28&d1=2026-01-28&endDate=2026-01-30&d2=2026-01-30&lodging=APARTMENT)

Condo

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America&regionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-01-28&d1=2026-01-28&endDate=2026-01-30&d2=2026-01-30&lodging=CONDO)

Cottage

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America&regionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-01-28&d1=2026-01-28&endDate=2026-01-30&d2=2026-01-30&lodging=COTTAGE)

## Check prices for these dates

Tonight

[14 Jan - 15 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=183431&startDate=2026-01-14&endDate=2026-01-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[15 Jan - 16 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=183431&startDate=2026-01-15&endDate=2026-01-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=183431&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=183431&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for St. Charles hotels

![Front of property](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/f7ac3cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/137ca358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room (2 Double Beds) | Desk, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/9f23656a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 Queen Bed | Living area | LED TV](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/dc85cf59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### White Valley Motel

[](https://www.expedia.co.uk/Rochester-Hotels-White-Valley-Motel.h12333567.Hotel-Information)

St. Charles

5.6/10

(128 reviews)

"Very nice owner i wil come back again thank you.. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rolando

£57

includes taxes & fees

18 Jan - 19 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-White-Valley-Motel.h12333567.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/d5501184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/687d1b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/fd6d967e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/f083bd82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Rochester South - Mayo Area by IHG

[](https://www.expedia.co.uk/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information)

Rochester

8.8/10

Excellent

(1,000 reviews)

"Clean room, clean hotel, friendly staff Would stay here again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chee

£63

includes taxes & fees

25 Jan - 26 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/b39d1efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/e31f1fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/288dd4d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/59be254c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

[](https://www.expedia.co.uk/Rochester-Hotels-Courtyard-By-Marriott-Rochester-Mayo-Clinic-AreaSaint-Marys.h1263391.Hotel-Information)

Kutzky Park

9.2/10

Wonderful

(776 reviews)

"Staff was very helpful and positive. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bradley

£80

includes taxes & fees

6 Feb - 7 Feb

[](https://www.expedia.co.uk/Rochester-Hotels-Courtyard-By-Marriott-Rochester-Mayo-Clinic-AreaSaint-Marys.h1263391.Hotel-Information)

![Pub](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/ed3fe960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillow-top beds, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/2f1620a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/12871cd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/5817de71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Rochester Mayo Clinic Area

[](https://www.expedia.co.uk/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester-Mayo-Clinic-Area.h69681188.Hotel-Information)

Kutzky Park

9.6/10

Exceptional

(486 reviews)

"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ann

£109

includes taxes & fees

13 Feb - 14 Feb

[](https://www.expedia.co.uk/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester-Mayo-Clinic-Area.h69681188.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080618/70cc02f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom | Living room | Pay films](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080618/ef35eee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free full breakfast ](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080618/4e8a78f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, free cots/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080618/1c37d6b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn by Marriott Rochester Mayo Clinic Area

[](https://www.expedia.co.uk/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area.h1080618.Hotel-Information)

Downtown Rochester

8.4/10

Very good

(201 reviews)

"Breakfast great and staff very helpful. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

John

£127

includes taxes & fees

16 Jan - 17 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area.h1080618.Hotel-Information)

![Presidential Suite, Multiple Beds | Living area | LCD TV](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/c7a0b093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/86063f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/74161f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Rochester Mayo Clinic Area

[](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information)

Downtown Rochester

9.6/10

Exceptional

(552 reviews)

"Very courteous staff, loved the valet guy!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jean

£147

includes taxes & fees

23 Jan - 24 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/64f360d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/bdf57892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/8468475f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/4db52fa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

[](https://www.expedia.co.uk/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information)

Kutzky Park

8.6/10

Excellent

(954 reviews)

"Friendly staff, good breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Missy

£80

includes taxes & fees

24 Jan - 25 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/76e5e57e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children’s pool](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/adc84b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/1a6136b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

[](https://www.expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information)

Rochester

7.2/10

Good

(1,031 reviews)

"Staff was courteous and breakfast was well stocked."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Doug

£64

includes taxes & fees

25 Jan - 26 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bba1b373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Indigo Rochester – Mayo Clinic Area by IHG

[](https://www.expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

Downtown Rochester

8.8/10

Excellent

(911 reviews)

"Great stay as always! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Misty

£65

includes taxes & fees

30 Jan - 31 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/77987087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/937e22b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/63ec118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Inn & Suites Rochester South Mayo Clinic

[](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information)

Rochester

8.4/10

Very good

(1,010 reviews)

"Rooms are always clean wonderful service from the staff. It’s a great place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jamie

£77

includes taxes & fees

25 Jan - 26 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/90393dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/9fcb392a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/79a3373a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/263c4c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

[](https://www.expedia.co.uk/Rochester-Hotels-Holiday-Inn-Express-Suites-Rochester-Mayo-Clinic-Area.h4913635.Hotel-Information)

Kutzky Park

8.8/10

Excellent

(771 reviews)

"the staff was friendly and helpful/ and the room was clean/ and good amenities"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

carol

£88

includes taxes & fees

18 Jan - 19 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Holiday-Inn-Express-Suites-Rochester-Mayo-Clinic-Area.h4913635.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/6a0aeefd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and dinner served](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/fc2af524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/9472e74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### EVEN Hotel Rochester - Mayo Clinic Area by IHG

[](https://www.expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information)

Kutzky Park

9.4/10

Exceptional

(979 reviews)

"The staff was very friendly and the room spotless. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judith

£104

includes taxes & fees

30 Jan - 31 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information)

![Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-1092e125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2560x4y0-89209858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/d609b8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Accessible, Refrigerator & Microwave | Blackout curtains, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2557x4y0-117f61d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

[](https://www.expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information)

Rochester

8.2/10

Very good

(800 reviews)

"This hotel was"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sheila

£80

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information)

![2 indoor pools](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/91eb68fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/51f9562a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/9070c6cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/bfbd8805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Rochester

[](https://www.expedia.co.uk/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester.h473100.Hotel-Information)

Rochester

8.8/10

Excellent

(543 reviews)

"My kids really enjoyed the pool, and so did I! Room was nice & clean. Staff were nice. I really appreciated the late checkout. (At least compared to other hotels, 12pm is late!) "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ashley

£84

includes taxes & fees

20 Jan - 21 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester.h473100.Hotel-Information)

![City view from property](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/50a69e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/7d048b62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/d5f4c6e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/c1a0e9f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marriott Rochester Mayo Clinic

[](https://www.expedia.co.uk/Rochester-Hotels-Marriott-Rochester-Mayo-Clinic.h3948.Hotel-Information)

Downtown Rochester

8.4/10

Very good

(527 reviews)

"it was a fantastic "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

£144

includes taxes & fees

16 Jan - 17 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Marriott-Rochester-Mayo-Clinic.h3948.Hotel-Information)

![Breakfast served](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/56e8351b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/a4f912ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillow-top beds, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/37670f4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillow-top beds, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/25614355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Rochester Downtown, MN

[](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information)

Downtown Rochester

8.8/10

Excellent

(861 reviews)

"Transportation services very good staff very helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joyce

£91

includes taxes & fees

6 Feb - 7 Feb

[](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/674459db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/w3830h2377x5y0-044007d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/90603a24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/50706b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

[](https://www.expedia.co.uk/Rochester-Hotels-Homewood-Suites-By-Hilton-Rochester-Mayo-Clinic-Area-Saint-Marys.h9120037.Hotel-Information)

Kutzky Park

9.2/10

Wonderful

(487 reviews)

"Being so close to St Mary's sure helped with our hospital stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kevin

£98

includes taxes & fees

14 Feb - 15 Feb

[](https://www.expedia.co.uk/Rochester-Hotels-Homewood-Suites-By-Hilton-Rochester-Mayo-Clinic-Area-Saint-Marys.h9120037.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/735141b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/7773d68b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/958ca8f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/0b6104cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Staybridge Suites Rochester - Mayo Clinic Area by IHG

[](https://www.expedia.co.uk/Rochester-Hotels-Staybridge-Suites-Rochester-St-Marys-Area.h59802871.Hotel-Information)

Kutzky Park

9.4/10

Exceptional

(431 reviews)

"Great room, location, very clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

£125

includes taxes & fees

24 Jan - 25 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Staybridge-Suites-Rochester-St-Marys-Area.h59802871.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/f5dad376.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 6 AM to midnight, pool loungers](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/2358f135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Two queens bed non smoking | Premium bedding, in-room safe, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/39857682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/81eb70a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Rochester-North

[](https://www.expedia.co.uk/Rochester-Hotels-Hampton-Inn-Suites-Rochester-North.h2825336.Hotel-Information)

Rochester

9.2/10

Wonderful

(1,002 reviews)

"Will stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

dennis

£76

includes taxes & fees

25 Jan - 26 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Hampton-Inn-Suites-Rochester-North.h2825336.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14200/14130/31fb9360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/1000000/20000/14200/14130/2f16cb4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/14200/14130/03b070f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14200/14130/6f2f8bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Inn & Suites by Radisson, Rochester, MN

[](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h14130.Hotel-Information)

Rochester

7.6/10

Good

(1,000 reviews)

"Very clean room and great breakfast!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shayna

£56

includes taxes & fees

25 Jan - 26 Jan

[](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h14130.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-28&endDate=2026-01-29&regionId=183431&adults=2&sort=RECOMMENDED&openPlayBack=true)

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## Learn more about St. Charles

St. Charles awaits: its natural setting and more! 

[See all hotels in St. Charles](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-28&endDate=2026-01-29&adults=2&regionId=183431)

![St. Charles is a rural Community in South East Minnesota](https://images.trvl-media.com/place/183431/30533b3b-ce9f-42e7-b976-83514176ce7e.jpg?impolicy=fcrop&w=900&h=599&p=1&q=high)

## Top St. Charles Hotel Reviews

![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg)

### Kahler Grand Hotel

10/10 Excellent

"The employees were very nice and polite. "

[](https://expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information)

![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg)

### Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Property was excellent. "

[](https://expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg)

### AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"clean room, great staff."

[](https://expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg)

### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

10/10 Excellent

"Clean and nice rooms"

[](https://expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information)

![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg)

### Spark by Hilton Rochester South

10/10 Excellent

"Clean, quiet and a spacious room at a reasonable price."

[](https://expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information)

![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg)

### Aspen Suites

10/10 Excellent

"The staff was very friendly, room was very clean "

[](https://expedia.co.uk/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information)

![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg)

### EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Great"

[](https://expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information)

![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg)

### Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"Fast and easy"

[](https://expedia.co.uk/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information)

![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg)

### Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"We enjoy staying at Kahler Inn & Suites. So nice to be so close to Mayo Clinic. You don't have to go outside. You can walk from the hotel tp Mayo. Everyone is so friendly and the breakfast is great!"

[](https://expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information)

## More cheap stays in St. Charles

![Super 8 by Wyndham Winona MN](https://images.trvl-media.com/lodging/1000000/910000/905900/905847/9b61bdfb_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN

£52

26 Jan - 27 Jan

includes taxes & fees

7.6/10 Good! (1,006 reviews)

[](https://expedia.co.uk/Winona-Hotels-Super-8-By-Wyndham-Winona-MN.h905847.Hotel-Information)

![Econo Lodge Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Econo Lodge Mayo Clinic Area

1850 S Broadway Rochester MN

£54

31 Jan - 1 Feb

includes taxes & fees

9/10 Wonderful! (916 reviews)

[](https://expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information)

![Days Inn by Wyndham Winona](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/046c7ce7_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn by Wyndham Winona

420 Cottonwood Dr Winona MN

£56

20 Jan - 21 Jan

includes taxes & fees

7.6/10 Good! (1,001 reviews)

[](https://expedia.co.uk/Winona-Hotels-Days-Inn-By-Wyndham-Winona.h25338.Hotel-Information)

![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

£64

16 Jan - 17 Jan

includes taxes & fees

7.8/10 Good! (1,002 reviews)

[](https://expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information)

![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn Rochester-South

1755 S Broadway Rochester MN

£67

3 Feb - 4 Feb

includes taxes & fees

9/10 Wonderful! (1,006 reviews)

[](https://expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information)

![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=28%2F01%2F2026&endDate=29%2F01%2F2026&selected=10007613&PinnedHotelID=10007613&HadPinnedHotel=true&regionId=183431)

8.8/10 Excellent! (1,007 reviews)

[](https://expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information)

## Frequently asked questions

### When is the best time to go to St. Charles?

> During the peak season, which spans from June to August, St Charles offers an array of events and attractions that appeal to those who appreciate quality experiences. Whether you're wandering through local markets, enjoying live music, or relaxing at outdoor cafés, the lively atmosphere is contagious. It's an ideal time for sightseeing, as the long days allow ample opportunity to soak in the stunning surroundings.
> 
>   
> For couples seeking a romantic escape, July is particularly special. The evenings are great for strolling along the waterfront or dining al fresco while watching the sunset, creating an unforgettable experience. The local community often hosts events that highlight the area's rich heritage and culinary delights, allowing you to engage with the culture in a meaningful way.
> 
>   
> If you're considering a visit that offers good value, November might be a less crowded option. While the temperatures drop, averaging around 10°C, this time of year allows you to explore St Charles at a more leisurely pace, often with lower accommodation costs and fewer tourists. Enjoy the unique charm of the area as you delve into museums and cosy eateries without the hustle and bustle of peak season.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a St. Charles hotel booking with Expedia?

### How much is the nightly rate at a St. Charles hotel?

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- [Flights to Minnesota City ](https://www.expedia.co.uk/Cheap-Flights-To-Minnesota-City.d133900.Travel-Guide-Flights)
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- [Chatfield Holidays ](https://www.expedia.co.uk/Chatfield.d183408.Holidays-City-Breaks)
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- [Visit Historic Southwest ](https://www.expedia.co.uk/Rochester-Historic-Southwest.dx553248635976469790)
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- [Car hire Minnesota City ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Minnesota-City.d133900.Car-Hire-Guide)
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- [Rochester Holiday Rentals ](https://www.expedia.co.uk/Rochester-Holiday-Rentals.d3041.Travel-Guide-HolidayRentals)

- [Book Hotels in St. Charles on Expedia.com ](https://www.expedia.com/St-Charles-Hotels.d183431.Travel-Guide-Hotels)

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