St. Ann Holidays from £1,275

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Your St. Ann Holiday

From its friendly locals to its laid-back lifestyle and beyond, there's much to like about St. Ann. Discover the wonders of this captivating city with a St. Ann holiday package that's customised for you. Ameristar Casino St. Charles, Hollywood Casino Amphitheatre and Historic Main Street are just a few of the many sights you'll want to explore during your trip to St. Ann. Check out Expedia's extensive range of travel options and begin planning your ultimate holiday to St. Ann today.

Top St. Ann Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG

3.5 out of 5
Price was £1,327, price is now £1,275 per person
£1,275
per person
16 Dec - 19 Dec
found 1 day ago
Return flight included
Edinburgh (EDI) to St. Louis (STL)
7.6/10 Good! (1,001 reviews)
It was clean and have no complaints.

Reviewed on 3 Nov 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was £1,502, price is now £1,302 per person
£1,302
per person
16 Dec - 19 Dec
found 1 day ago
Return flight included
Edinburgh (EDI) to St. Louis (STL)
9.2/10 Wonderful! (1,677 reviews)
My husband and I stayed here on our wedding night. We parked in the parking garage after checking in and were able to go right into the hallway near the elevators. The jacuzzi tub was amazing! I loved that they had towels specifically for makeup as well as a makeup wipe by the sink in the bathroom because I had forgotten to bring my own. The bed was so comfortable and you couldn’t hear other people in the hallway. The continental breakfast served what most hotels serve but everything tasted so much better! We are planning on staying again on our first anniversary!

Reviewed on 6 Nov 2026

Fairfield Inn & Suites Wentzville

Fairfield Inn & Suites Wentzville

3 out of 5
Price was £1,372, price is now £1,306 per person
£1,306
per person
16 Dec - 19 Dec
found 1 day ago
Return flight included
Edinburgh (EDI) to St. Louis (STL)
9/10 Wonderful! (723 reviews)
Very friendly and helpful staff. Great place to stay if you have pets.

Reviewed on 3 Nov 2026

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

3 out of 5
Eastport
Price was £1,344, price is now £1,290 per person
£1,290
per person
16 Dec - 19 Dec
found 1 day ago
Return flight included
Edinburgh (EDI) to St. Louis (STL)
7.4/10 Good! (1,002 reviews)
.

Reviewed on 6 Nov 2026

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

3 out of 5
Riverport
Price was £1,344, price is now £1,290 per person
£1,290
per person
16 Dec - 19 Dec
found 1 day ago
Return flight included
Edinburgh (EDI) to St. Louis (STL)
7.8/10 Good! (1,008 reviews)
Our room was clean and comfortable. I work nights so we went with the 1 bedroom option. It was nice to be able to close the door. I didn’t hear the tv from the living room, him talking on the phone or anything. Breakfast was nice, comfortable sitting area in the common area. Patio looked nice although we didn’t utilize it. We did have an issue with the ice maker, they were prompt in coming to look at it. The only complaints I have are the doors around the building that have signs requiring a key card we’re not locked and the luggage cart is triangular shape, do not drive well or hold as much as a standard luggage cart.

Reviewed on 6 Nov 2026

St. Ann Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)
Population
13,000
Max Temp Winter
4ºC
Max Temp Summer
29ºC
Top Sights
St. Louis Zoo, Magic House - St. Louis Childrens Museum and Fox Theatre

Top hotels in St. Ann

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is £79 per night from 11 Nov to 12 Nov
£79
11 Nov - 12 Nov
includes taxes & fees
9.4/10 Exceptional! (3,358 reviews)
"Great reception."

Reviewed on 6 Nov 2026

Pear Tree Inn St. Louis Airport
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

3 out of 5
10820 Pear Tree Lane St. Ann MO
Fully refundableReserve now, pay when you stay
The price is £89 per night from 23 Nov to 24 Nov
£89
23 Nov - 24 Nov
includes taxes & fees
9.2/10 Wonderful! (1,730 reviews)
"Everything was AMAZING! Staff was fantastic!!"

Reviewed on 7 Nov 2026

Wingate by Wyndham St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is £125 per night from 11 Nov to 12 Nov
£125
11 Nov - 12 Nov
includes taxes & fees
9.6/10 Exceptional! (3,821 reviews)
"The Drury was beautiful with very welcoming staff. Their free evening dinner and drinks was an amazing unexpected treat. The morning staff was very attentive and the breakfast was incredible."

Reviewed on 7 Nov 2026

Drury Plaza Hotel St. Louis at the Arch
See all 1,983 properties in St. Ann
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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What to do in St. Ann

Pappy's Smokehouse

Private Tour of St. Louis's Iconic BBQ Joints & Breweries

£104
per adult
Private Tour of St. Louis's Iconic BBQ Joints & Breweries
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

£18
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour

St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour

£13
per traveller
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
See all activities in St. Ann

Frequently asked questions

Why should I book my St. Ann holiday with Expedia?
Choose Expedia to organise your next big adventure with ease, all in the same place. Our insider tip for bagging a great deal on a St. Ann retreat? Bundle your hotel, flights and/or car hire into a package holiday. Then throw in a few awesome tours and activities. Most bookings also have flexible cancellation policies, so there's no need to stress if you have to switch up your travel plans. Round-the-clock help with making tweaks to your trip is available via our Customer Service Portal link.
When is the best time of year to holiday in St. Ann?
Into sightseeing but don't like huge crowds? Plan your St. Ann trip for November, December and January. Typically, it's a lot quieter than it is in March, August and October. To give you an idea of the type of weather you can experience, the average daytime temperature in January, the coolest time of year in St. Ann, is 0ºC. The warmest time here is July, when temperatures reach an average of 25ºC.
What is the top hotel for my holiday in St. Ann?
Best Western Route 66 Rail Haven sets the stage for an exciting adventure in St. Ann, offering all the comforts and conveniences you need and more.
How do I get a cheap holiday to St. Ann?
Our St. Ann holidays offer plenty of savings for the savvy wanderer. For the best deal, simply bundle your flights, hotels and activities. But impressive bargains are only the start of your next memorable adventure. Book with Expedia and and you'll have over 400 air carriers and 321,000 hotel options around the world to pick from. No matter your budget or style, there's a holiday here that's perfect for you. Learn more about how you can save money on your holiday when you combine your flight and hotel bookings with Expedia.
What should I do on my St. Ann holiday?
Offering top attractions such as St. Louis Zoo and Washington University in St. Louis, a holiday in St. Ann is full of exciting places to visit. Forest Park and Ameristar Casino St. Charles are a couple of other sights also worth a look.
Do I need a visa for my St. Ann holiday?
Visa requirements for St. Ann vary depending on your nationality and the purpose of your visit. We recommend checking official government websites to determine if you need a visa for your trip. They'll also give you the most up-to-date information, including details about application procedures or any supporting documentation you may need. Research your visa requirements well in advance to ensure a smooth travel experience. Finally, double-check to see that your passport is valid for a further six months from the date of your return.
What should I wear on my St. Ann holiday?
Though everyone's style differs, it can help to have some guidelines for what to wear on your holiday in St. Ann. Consider browsing social media before leaving for inspiration on fashion trends or dress codes. Pack with confidence by looking up the weather conditions in St. Ann. July brings the warmest temperatures, with daytime averages of 25ºC, while January days average 0ºC, making it the coolest time of the year.
What does an Expedia St. Ann holiday include?
Flights, hotels and car hires, or any combination of the three — you decide! Whether you're visiting St. Ann on a family road trip or adventuring with your friends, there's a package to suit your style and budget. Once you've made your booking, why not add on some tours and experiences? Discover a huge range of property types and pick one that suits your group size. The most in-demand holiday rentals here are private holiday homes and apartments. With Expedia, you can easily tailor-make your St. Ann retreat any way you want.
Does Expedia offer Book Now, Pay Later St. Ann holidays?
Good news! We do. Expedia has teamed up with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply select the payment plan that works for you during the checkout process and take away the stress of budgeting for your next trip. Don't forget to bundle your flights, accommodation and car hire with Expedia to get the biggest bang for your travel buck. Take a look at our flexible payment options below:

  • Pay monthly holidays: Klarna offers payments in multiple transactions that fit all budgets, so you can lock in that well-deserved holiday sooner.
  • No-deposit holidays: When you want to grab an awesome deal but don't have the full amount yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to lock in your getaway.

Can I choose my airline with a St. Ann Expedia holiday?
Yes, you're in control. We offer more than 400 partner airlines around the world, so you can tailor your St. Ann adventure according to your budget and style.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.