A grand building with domed towers, arched walkways, and a well-manicured garden.

Search Business Hotels in Southwest Missouri

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Check availability on Southwest Missouri Business Hotels

Tonight
25 Sept - 26 Sept
Tomorrow
26 Sept - 27 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Southwest Missouri business-friendly hotels

A La Quinta hotel entrance with a modern design, featuring a prominent logo, a covered entrance, and a landscaped front with benches and potted plants.
A hotel room with a bed, a desk, a chair, a small table, and a painting on the wall.
A gym with weight benches, dumbbells, a bench press, a treadmill, and an elliptical machine.
A modern lobby with a fireplace, seating area, and a reception desk with a 'Historic Route 66' sign.

1. La Quinta Inn & Suites by Wyndham Springfield Airport/Rte 66

La Quinta Inn & Suites by Wyndham Springfield Airport/Rte 66
Tom Watkins
United States
Akiba
£83
includes taxes & fees
11 Oct - 12 Oct
La Quinta Inn & Suites by Wyndham Springfield Airport/Rte 66
A hotel room with a bed, bedside table, lamp, and a painting of a sunset.
A lobby with a mural, seating area, and a refrigerator labeled 'NOURISH' and 'RECHARGE'.
A hotel entrance with a modern design, featuring a prominent logo and the name 'Clarion Pointe by Choice Hotels'.
A gym with exercise equipment, a treadmill, and a wall mural of athletes.

2. Clarion Pointe Springfield Southeast

Clarion Pointe Springfield Southeast
Galloway Village
United States
Stephen
£74
includes taxes & fees
4 Oct - 5 Oct
Clarion Pointe Springfield Southeast
A hotel room with a bed, a sofa, a coffee table, a desk, and a mirror.
A pool area with a pool, chairs, and a sign indicating pool rules.
A dining area with wooden tables and chairs, a kitchen in the background, and a blue accent wall.

3. Best Western Plus Springfield Airport Inn

Best Western Plus Springfield Airport Inn
Springfield
United States
Sue
£87
includes taxes & fees
11 Oct - 12 Oct
Best Western Plus Springfield Airport Inn
A spacious indoor dining area with multiple tables and chairs, a kitchen area, and large windows allowing natural light.
A spa area with a hot tub, a pool, and a seating area with tables and chairs.
A modern kitchen with a long counter, wooden cabinets, and a backsplash.
A modern lobby with a reception desk, seating area, and a high ceiling with recessed lighting.

4. Drury Inn & Suites Springfield, MO

Drury Inn & Suites Springfield, MO
Springfield
United States
Deanna
£98
includes taxes & fees
25 Oct - 26 Oct
Drury Inn & Suites Springfield, MO
A modern hotel lobby with a sofa, a coffee table, and a reception desk.
A hotel entrance with a red archway and stone pillars.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
A hotel room with a sofa, armchair, and a small table. There is a window with curtains, a flat-screen TV mounted on the wall, and a lamp on a side table.

5. Baymont by Wyndham Springfield I-44

Baymont by Wyndham Springfield I-44
Doling
United States
Rebecca
£76
includes taxes & fees
27 Sept - 28 Sept
Baymont by Wyndham Springfield I-44
A hotel room with two beds, a wooden headboard, bedside tables with lamps, and a small nightstand.
A gym with treadmills, weight machines, and exercise mats.
A conference room with rows of tables and chairs, a flat-screen TV on the wall, and a door in the background.
A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

6. Holiday Inn Express & Suites Springfield North by IHG

Holiday Inn Express & Suites Springfield North by IHG
Springfield
United States
Jerry
£98
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Express & Suites Springfield North by IHG
A modern office space with ergonomic chairs, a large flat-screen TV, and a view of the city through large windows.
A spacious lobby with a high ceiling, a central seating area with a colorful rug, and a modern chair.
A modern bar area with high stools and a patterned carpet.
A bar area with a curved counter, multiple bar stools, and a seating area with chairs.

7. Best Western Premier Springfield Plaza District Hotel

Best Western Premier Springfield Plaza District Hotel
Oak Grove
United States
Donna
£85
includes taxes & fees
1 Oct - 2 Oct
Best Western Premier Springfield Plaza District Hotel
A modern hotel room with a large bed, a desk with a sink, and a view of the cityscape through large windows.
A modern kitchen with a large island, bar stools, a window with a city view, and pendant lighting.
A rooftop lounge with wooden flooring, various seating options including sofas and chairs, a round table, and potted plants.
A bar area with a checkered floor, bar stools, and a long counter with a barista station.

8. Hotel Vandivort

Hotel Vandivort
Downtown Springfield
United States
George
£134
includes taxes & fees
1 Oct - 2 Oct
Hotel Vandivort
A conference room with a granite table, cushioned chairs, a fruit bowl, framed pictures, and a flat-screen TV.
The exterior of Hampton Inn with a clear sign, a welcome sign, and a clearance height sign.
A living room with patterned armchairs, a dark sofa, a glass coffee table, and framed artwork on the walls.
A business center with two computers, a printer, and a lamp. There are signs indicating the business center is available 24 hours and providing emergency and front desk contact information.

9. Hampton Inn Springfield-South

Hampton Inn Springfield-South
Galloway Village
United States
Ashley
£87
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Springfield-South
An outdoor patio area with wicker furniture, a central fire pit, and large windows.
A hotel with a stone facade, large windows, and a clear blue sky.
An indoor swimming pool with clear water, surrounded by a tiled floor and a glass wall.
A lobby with a fireplace, large windows, and a view of the outdoors.

10. Hilton Garden Inn Springfield, MO

Hilton Garden Inn Springfield, MO
Lake Springfield
United States
daryl
£103
includes taxes & fees
17 Oct - 18 Oct
Hilton Garden Inn Springfield, MO
View all properties

Top Southwest Missouri Hotel Reviews

Still Waters Resort

Still Waters Resort

10/10 Excellent
"Love it"
Lilian 3-night trip
Posted 7 hours ago
Still Waters Resort
Seven Gables Inn

Seven Gables Inn

8/10 Good
"good stay friendly staff will use again."
Doug 3-night trip
Posted 8 hours ago
Seven Gables Inn
Clarion Inn Branson

Clarion Inn Branson

10/10 Excellent
"Very nice hotel. Comfortable, clean and staff was very professional. Loved the balcony by the pool."
Frances C 1-night trip
Posted 9 hours ago
Clarion Inn Branson
Chateau On The Lake Resort Spa and Convention Center

Chateau On The Lake Resort Spa and Convention Center

10/10 Excellent
"Hotel is nice but still a bit outdated. I liked that it was away from everything, the lake is beautiful, staff was friendly, and the restaurant was good. Only thing I didn’t like is that even after turning the hot tub on, the jets barely worked."
Kristen 4-night trip
Posted 10 hours ago
Chateau On The Lake Resort Spa and Convention Center
The Suites at Fall Creek

The Suites at Fall Creek

8/10 Good
"Clean and very comfortable"
Rockford 4-night trip
Posted 10 hours ago
The Suites at Fall Creek
Lodge Of The Ozarks

Lodge Of The Ozarks

10/10 Excellent
"Everything was Wonderful close right on the main street"
Cynthia 2-night trip
Posted 11 hours ago
Lodge Of The Ozarks
The Stone Castle Hotel & Conference Center

The Stone Castle Hotel & Conference Center

10/10 Excellent
"The nicest staff"
Jimmie 2-night trip
Posted 11 hours ago
The Stone Castle Hotel & Conference Center
Hyatt Vacation Club at The Lodges at Timber Ridge, Branson

Hyatt Vacation Club at The Lodges at Timber Ridge, Branson

10/10 Excellent
"Everything was amazing except we missed the pool being open"
Marilyn 3-night trip
Posted 13 hours ago
Hyatt Vacation Club at The Lodges at Timber Ridge, Branson
Hotel Grand Victorian

Hotel Grand Victorian

10/10 Excellent
"Beds were super comfy! It was clean and safe. And Don the front desk guy was the man!! The Don!"
D'Amber 1-night trip
Posted 13 hours ago
Hotel Grand Victorian

Frequently asked questions

How much do business hotels in Southwest Missouri cost?
Business hotels in Southwest Missouri range between £74 and £134 per night. This means you can reserve a property with amenities like conference rooms and workspaces at a price that fits your work budget. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business hotels are there in Southwest Missouri?
Southwest Missouri has 240 business hotels to pick from. Whether you're hosting a conference or meeting or simply working remotely, these stays are equipped with the services and amenities you need to be productive.
Why book your business hotel in Southwest Missouri with Expedia?
Here at Expedia, it's our job to help you land the ideal stay at the right price. From fancy, corporate-friendly properties to affordable motels filled with handy amenities, you'll have your next work trip arranged in a few quick clicks.
How can I find cheap business hotels in Southwest Missouri?
Select the "business friendly" filter, listed under the "traveller experience" heading, to find cheap business hotels in Southwest Missouri. Then refine your search by your budget and preferred hotel star rating. Staying away from the centre is another easy way to save.

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