Title: Lester E. Cox Medical Center South in Springfield | Expedia.co.uk [Lester E. Cox Medical Center South Hotels](https://expedia.co.uk/Lester-E-Cox-Medical-Center-South-Hotels.0-l6164130-0.Travel-Guide-Filter-Hotels)[Flights to Springfield](https://expedia.co.uk/Cheap-Flights-To-Springfield.d602962.Travel-Guide-Flights)[Things to do in Springfield](https://expedia.co.uk/Things-To-Do-In-Springfield.d602962.Travel-Guide-Activities)[Lester E. Cox Medical Center South Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lester-E-Cox-Medical-Center-South.d6164130.Car-Hire-Guide)[Springfield Holidays](https://expedia.co.uk/Springfield.d602962.Holidays-City-Breaks) # Lester E. Cox Medical Center South ## Visit Lester E. Cox Medical Center South Activities [Springfield travel guide](https://expedia.co.uk/Springfield.dx602962) * * * * * * ### Popular places to visit ![Springfield Conservation Nature Center](https://mediaim.expedia.com/destination/1/72a41e5e0e9f828bc56c49f88d9e346b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Springfield Conservation Nature Center Enjoy a stop at Springfield Conservation Nature Center, an entertaining place to visit in Springfield. You can attend a sporting event while in the area. [](https://expedia.co.uk/Springfield-Conservation-Nature-Center-Springfield.d553248621532648159.Attraction) ![Wonders of Wildlife Museum & Aquarium](https://mediaim.expedia.com/destination/2/abef4702c17663af3b1436652427b545.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Wonders of Wildlife Museum & Aquarium Make time to visit the sea life at Wonders of Wildlife Museum & Aquarium during your holiday to Springfield. Experience the area's entertainment choices or attend a sporting event. [](https://expedia.co.uk/Wonders-Of-Wildlife-Museum-Aquarium-Springfield.d6064841.Attraction) ![Nathanael Greene/Close Memorial Park](https://mediaim.expedia.com/destination/2/91d48396ee5b6bdcf7f92a0a1b3f0476.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Nathanael Greene/Close Memorial Park Explore the great outdoors at Nathanael Greene/Close Memorial Park, a lovely green space in Springfield. Experience the area's entertainment choices or attend a sporting event. [](https://expedia.co.uk/Nathanael-GreeneClose-Memorial-Park-Springfield.d553248621532648157.Attraction) ![Mizumoto Japanese Stroll Garden](https://mediaim.expedia.com/destination/2/d304369a2265e50cd4b9ac2bd45d68f8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Mizumoto Japanese Stroll Garden Explore the great outdoors at Mizumoto Japanese Stroll Garden, a lovely green space in Springfield. Experience the area's entertainment choices or attend a sporting event. [](https://expedia.co.uk/Mizumoto-Japanese-Stroll-Garden-Springfield.d553248621532648156.Attraction) #### Wheeler Heart and Vascular Center If Wheeler Heart and Vascular Center is what brings you to town, hopefully you'll have a chance to explore more of Springfield. [](https://expedia.co.uk/Wheeler-Heart-And-Vascular-Center-Springfield.d6164145.Attraction) #### Hulston Cancer Center If Hulston Cancer Center is what brings you to town, hopefully you'll have a chance to explore more of Springfield. [](https://expedia.co.uk/Hulston-Cancer-Center-Springfield.d6164140.Attraction) * * * ## Top Hotel Deals ## Check availability on hotels close to Lester E. Cox Medical Center South [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-10-31&endDate=2025-11-01) [Tonight](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-10-31&endDate=2025-11-01) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-10-31&endDate=2025-11-01) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-10-31&endDate=2025-11-01)[31 Oct - 1 Nov](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-10-31&endDate=2025-11-01) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-11-01&endDate=2025-10-02) [Tomorrow night](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-11-01&endDate=2025-10-02) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-11-01&endDate=2025-10-02) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-11-01&endDate=2025-10-02)[1 Nov - 2 Nov](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=2025-11-01&endDate=2025-10-02) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [This weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025)[31 Oct - 2 Nov](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6164130&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) ![University Plaza Hotel and Convention Center Springfield](https://images.trvl-media.com/lodging/1000000/30000/22900/22870/6062282b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### University Plaza Hotel and Convention Center Springfield 333 S John Q Hammons Pkwy, Springfield, MO [](https://expedia.co.uk/Springfield-Hotels-University-Plaza-Hotel-And-Convention-Center-Springfield.h22870.Hotel-Information) ![Bass Pro Shops Angler's Lodge](https://images.trvl-media.com/lodging/23000000/22600000/22590900/22590856/420ffb1d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Bass Pro Shops Angler's Lodge 621 W Sunshine St, Springfield, MO [](https://expedia.co.uk/Springfield-Hotels-Bass-Pro-Shops-Anglers-Lodge.h22590856.Hotel-Information) ![The Bradford Hotel, an Ascend Collection Hotel](https://images.trvl-media.com/lodging/1000000/30000/28400/28324/abef7ad6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Bradford Hotel, an Ascend Collection Hotel 1260 E Independence St, Springfield, MO [](https://expedia.co.uk/Springfield-Hotels-Arbor-Suites-Medical-Mile.h28324.Hotel-Information) ![Extended Stay America Select Suites Springfield South](https://images.trvl-media.com/lodging/1000000/80000/79500/79488/024cd62e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Extended Stay America Select Suites Springfield South 1333 E Kingsley St, Springfield, MO [](https://expedia.co.uk/Springfield-Hotels-Extended-Stay-America-Suites-Springfield-South.h79488.Hotel-Information) ![Residence Inn by Marriott Springfield](https://images.trvl-media.com/lodging/1000000/800000/799800/799701/1a634205_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Residence Inn by Marriott Springfield 1303 E Kingsley St, Springfield, MO [](https://expedia.co.uk/Springfield-Hotels-Residence-Inn-By-Marriott-Springfield.h799701.Hotel-Information) ![Holiday Inn Express and Suites Springfield Medical District by IHG](https://images.trvl-media.com/lodging/2000000/1510000/1505400/1505316/e3469c49_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express and Suites Springfield Medical District by IHG 310 E Monastery, Springfield, MO [](https://expedia.co.uk/Springfield-Hotels-Holiday-Inn-Express-And-Suites-Springfield-Medical-District.h1505316.Hotel-Information) ![Comfort Inn South - Springfield](https://images.trvl-media.com/lodging/1000000/90000/84400/84334/bfc72a9a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn South - Springfield 3776 S Glenstone Avenue, Springfield, MO [](https://expedia.co.uk/Springfield-Hotels-Comfort-Inn-South-Springfield.h84334.Hotel-Information) ![Greenstay Inn & Suites CourtView](https://images.trvl-media.com/lodging/1000000/20000/17300/17276/99bf8860_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Greenstay Inn & Suites CourtView 3370 East Battlefield, Springfield, MO [](https://expedia.co.uk/Springfield-Hotels-Greenstay-Inn-Suites-CourtView.h17276.Hotel-Information) ![Candlewood Suites Springfield-Medical District](https://images.trvl-media.com/lodging/2000000/1830000/1828400/1828359/c5a13f20_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Candlewood Suites Springfield-Medical District 1035 E Republic Rd, Springfield, MO [](https://expedia.co.uk/Springfield-Hotels-Candlewood-Suites-South-Springfield.h1828359.Hotel-Information) [See all 708 properties in Lester E. Cox Medical Center South](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6164130) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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