The Best Hotels Closest to Lester E. Cox Medical Center South in Springfield - 2026 Updated Prices

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Our top choices for Lester E. Cox Medical Center South hotels

A conference room with a granite table, cushioned chairs, a fruit bowl, framed pictures, and a flat-screen TV.

The exterior of Hampton Inn with a clear sign, a welcome sign, and a clearance height sign.

A gym with various exercise machines, a clock, and a motivational sign.

A living room with patterned armchairs, a dark sofa, a glass coffee table, and framed artwork on the walls.

1. Hampton Inn Springfield-South

Galloway Village, 1.2 mi from Lester E. Cox Medical Center South

Ashley

£90

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a blue sofa, two single beds, a nightstand, a lamp, and a framed picture on the wall.

A hotel dining area with a buffet, seating arrangements, and a kitchen counter.

A living room with a blue sofa, a small round table, a patterned carpet, and a kitchenette area.

A Holiday Inn Express & Suites hotel with a parking lot, a covered entrance, and a view of the surrounding area.

2. Holiday Inn Express and Suites Springfield Medical District by IHG

1 mi from Lester E. Cox Medical Center South

Loyola

£108

includes taxes & fees

8 Nov - 9 Nov

An outdoor patio area with red seating, a fire feature, and tables and chairs.

A modern hotel room with a large bed, a desk with a chair, a mirror, and a painting on the wall.

A modern living room with a sectional sofa, a coffee table, and yellow armchairs. There is a dining area with a table and chairs in the background.

A modern hotel with a dark facade, multiple windows, and an American flag.

3. Homewood Suites by Hilton Springfield Medical District

Southside, 0.9 mi from Lester E. Cox Medical Center South

Aaron

£116

includes taxes & fees

31 Oct - 1 Nov

A hotel room with two beds, a desk, a chair, a TV, and a bathroom with a sink and mirror.

A modern hotel room with a sofa, armchair, and a dining area with a kitchen in the background.

A modern kitchen with a stainless steel microwave, a coffee maker, and a refrigerator.

A spacious lobby with a pool, comfortable seating, and a reception desk.

4. Candlewood Suites Springfield-Medical District

0.6 mi from Lester E. Cox Medical Center South

Richard

£101

includes taxes & fees

1 Nov - 2 Nov

A spacious living area with large windows, a bar, and modern furniture.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a large windowed area.

A modern hotel building with a prominent 'element by Westin' sign, multiple floors, and a covered entrance area.

A spacious kitchen with a large island, ample seating, and a view of the cityscape through large windows.

5. Element by Marriott Springfield South

Meador Park, 1 mi from Lester E. Cox Medical Center South

Nathaniel

£124

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with wicker furniture, a central fire pit, and large windows.

An indoor swimming pool with clear water, surrounded by a tiled floor and a glass wall.

A hotel with a stone facade, large windows, and a clear blue sky.

A spacious hotel lobby with high ceilings, large windows, and a central seating area with tables and chairs.

6. Hilton Garden Inn Springfield, MO

Lake Springfield, 1.7 mi from Lester E. Cox Medical Center South

daryl

£103

includes taxes & fees

31 Oct - 1 Nov

A spacious lounge area with comfortable seating, a fireplace, and artwork on the walls.

A hotel room with a desk, chair, TV, fireplace, bed, and a small dining area.

A modern kitchen with a central island, bar stools, a dining table, and a bar area.

A buffet setup with various food items, a clock, and a coffee machine.

7. Residence Inn by Marriott Springfield

Southside, 0.5 mi from Lester E. Cox Medical Center South

Jacob

£101

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a desk with a computer, a TV, and a coffee maker.

A hotel reception area with a counter displaying various alcohol bottles, a menu board, and artwork on the walls.

A compact hotel room with a sofa, a small table, a TV, and a desk with a coffee machine.

An indoor swimming pool with a tiled floor, a pool ladder, and a glass door leading to another room.

8. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 1.8 mi from Lester E. Cox Medical Center South

Denise

£78

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a flat-screen TV, a fireplace, a sofa, and a dining area with a kitchen counter.

A kitchen area with a coffee machine, a buffet setup, and a dining table with chairs.

A modern living room with a fireplace, a sofa, a TV, and a staircase leading to a bedroom.

A spacious living area with a sofa, a ceiling fan, a staircase, and a kitchen area.

9. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.1 mi from Lester E. Cox Medical Center South

Arthur

£79

includes taxes & fees

9 Nov - 10 Nov

An indoor swimming pool with a glass ceiling, surrounded by lounge chairs and a view of the outdoors.

A Comfort Inn hotel with a modern facade, a covered entrance, and a parking lot.

A modern restaurant with a stone backsplash, wooden cabinets, and a herringbone floor pattern.

A modern living room with blue sofas, a stone accent wall, and a bookshelf.

10. Comfort Inn South - Springfield

Galloway Village, 1.4 mi from Lester E. Cox Medical Center South

Roger

£83

includes taxes & fees

8 Nov - 9 Nov

A modern hotel lobby with a leather sofa, green chairs, a black coffee table, and a kitchen area with a green countertop.

A hotel with a prominent sign, a covered parking area, and a well-lit entrance.

A spacious indoor dining area with multiple round tables and chairs, large windows, and a modern staircase.

A hotel room with two beds, a desk with a chair, a flat-screen TV, and a large window with curtains.

11. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.3 mi from Lester E. Cox Medical Center South

William

£76

includes taxes & fees

8 Nov - 9 Nov

A hotel lobby with a reception desk, a staircase, and a seating area.

A modern hotel lobby with a sofa, armchairs, a coffee table, and a staircase.

A kitchen with a wooden table and chairs, a coffee machine, a fruit juicer, and a refrigerator.

A swimming pool with a hot tub, tiled floor, and a few lounge chairs.

12. Sleep Inn Springfield South I60 near Medical District

1.1 mi from Lester E. Cox Medical Center South

Dina

£72

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a large bed, a chair, a nightstand, a lamp, and a door.

A hotel room with a brown leather sofa, a small table, a floor lamp, and a green accent wall.

A compact kitchenette with white cabinets, a sink, a microwave, and a refrigerator.

A hotel reception area with a reception desk, a framed artwork, and an exit sign.

13. Extended Stay America Select Suites Springfield South

Southside, 0.5 mi from Lester E. Cox Medical Center South

Crystal

£62

includes taxes & fees

30 Oct - 31 Oct

A hotel room with a bed, bedside table, lamp, and a painting of a sunset.

A gym with exercise equipment, a treadmill, and a wall mural of athletes.

A lobby with a mural, seating area, and a refrigerator labeled 'NOURISH' and 'RECHARGE'.

14. Clarion Pointe Springfield Southeast

Galloway Village, 3 mi from Lester E. Cox Medical Center South

Amanda

£72

includes taxes & fees

19 Oct - 20 Oct

A hotel room with two beds, a wooden headboard, bedside tables with lamps, and a small nightstand.

A Holiday Inn Express & Suites hotel with a parking lot and multiple vehicles.

A gym with treadmills, weight machines, and exercise mats.

A conference room with rows of tables and chairs, a flat-screen TV on the wall, and a door in the background.

15. Holiday Inn Express & Suites Springfield North by IHG

7.3 mi from Lester E. Cox Medical Center South

Jerry

£90

includes taxes & fees

25 Oct - 26 Oct

A spacious indoor dining area with multiple tables and chairs, a kitchen area, and large windows allowing natural light.

A Drury Inn & Suites hotel with a modern design, featuring a prominent entrance and stone pillars.

A modern kitchen with a long counter, wooden cabinets, and a backsplash.

A modern lobby with a reception desk, seating area, and a high ceiling with recessed lighting.

16. Drury Inn & Suites Springfield, MO

6.9 mi from Lester E. Cox Medical Center South

Renee

£92

includes taxes & fees

25 Oct - 26 Oct

A cozy living room with a stone fireplace, comfortable seating, and a large mirror reflecting the room.

A hotel lobby with a large bar area, seating, a fireplace, and framed pictures on the walls.

A hotel room with a bed, bedside lamps, a desk with a sink, and a framed picture on the wall.

An indoor swimming pool with a clear water line, surrounded by lounge chairs and tables.

17. Hampton Inn Springfield-Southeast

Galloway Village, 3 mi from Lester E. Cox Medical Center South

Donna Sue

£95

includes taxes & fees

1 Nov - 2 Nov

A modern hotel room with a kitchenette, a flat-screen TV, a bed, and a large window.

An outdoor patio area with a stone wall, wooden pergola, and seating arrangements including a sofa and chairs.

A modern kitchen with wooden cabinets, a countertop with various kitchen items, and a wall-mounted shelf with decorative objects.

A hotel reception area with a modern design, including a reception desk, a wall with geometric patterns, and a minibar.

18. SpringHill Suites by Marriott Springfield North

Parkwood, 7.2 mi from Lester E. Cox Medical Center South

Amanda

£101

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio with stone walls, round tables, chairs, and umbrellas.

A modern living room with a wooden dining table, comfortable seating, a stone accent wall, and a large window.

An indoor swimming pool with clear glass walls, lounge chairs, and a lifeguard chair.

A Fairfield Inn & Suites Marriott hotel with a modern design, featuring a prominent entrance and a parking lot.

19. Fairfield Inn & Suites by Marriott Springfield North

Doling, 6.6 mi from Lester E. Cox Medical Center South

Kristal

£92

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a large bed, a desk with a sink, and a view of the cityscape through large windows.

A modern building with a prominent V-shaped entrance and large glass windows.

A rooftop lounge with wooden flooring, various seating options including sofas and chairs, a round table, and potted plants.

A bar area with a checkered floor, bar stools, and a long counter with a barista station.

20. Hotel Vandivort

Downtown Springfield, 4.2 mi from Lester E. Cox Medical Center South

George

£128

includes taxes & fees

11 Nov - 12 Nov

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Property class	Guest rating
Hampton Inn Springfield-South	9.4 Exceptional 717 reviews	View
Holiday Inn Express and Suites Springfield Medical District by IHG	9.4 Exceptional 1,003 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 Exceptional 567 reviews	View
Candlewood Suites Springfield-Medical District	9.2 Wonderful 434 reviews	View
Element by Marriott Springfield South	9.2 Wonderful 158 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

MainStay Suites Springfield South - Battlefield Rd

10/10 Excellent

"This truly is a hidden gem. We circled the block twice according to gps. :) Rooms have been updated. We had a good nights sleep"

Bass Pro Shops Angler's Lodge

10/10 Excellent

"Easy check in and convenient location"

Holiday Inn Express and Suites Springfield Medical District by IHG

10/10 Excellent

"Nice breakfast"

Comfort Inn South - Springfield

10/10 Excellent

"This is a clean, well located property with multiple tasty breakfast options. There are many stores and restaurants very close by and good access to the main roads for travel."

Sleep Inn Springfield South I60 near Medical District

10/10 Excellent

"The room was cleaned"

Peaceful Retreat near Medical Mile in Springfield

10/10 Excellent

"Soooo clean. Has everything you need!!! Love this property!!! Will be back"

Candlewood Suites Springfield-Medical District

10/10 Excellent

"There was some issues with smells from other unit, people use these for extended stays and must cook alot in them, so we woke up to burning smells throughout the night and early morning."

Comfortable Home Near CoxHealth & MSU - Fenced Yard

10/10 Excellent

"The house was better than described, very comfortable and everything is right there I mean right there, I was pleasantly surprised on how I was able to get ot everything in no time flat, the only thing that was a hike was the airport."

Cozy Central Home by CoxHealth & MSU - Fenced Yard

10/10 Excellent

"Property was clean and properly prepared for our stay. The deck was a wonderful addition for our gatherings."

Frequently asked questions

What are the top-rated hotels near Lester E. Cox Medical Center South?

For those seeking top-rated accommodations near Lester E. Cox Medical Center South in Springfield, Missouri, here are some excellent options that combine comfort and quality.Walnut Street InnWalnut Street Inn, rated 9.6 by travellers, is a charming 3.5-star hotel located just 7.6 km from Lester E. Cox Medical Center South. This Victorian-designed hotel offers a warm atmosphere with amenities such as a cozy garden, a terrace, and complimentary daily breakfast. Guests can unwind in the beautiful yard or enjoy a game of billiards. The inn also features off-street parking and personalized concierge services to enhance the stay.The Mansion at ElfindaleThe Mansion at Elfindale is another fantastic choice, a review rating of 9.6 and situated only 7.2 km from Lester E. Cox Medical Center South. This 3.5-star hotel provides a luxurious experience with its furnished balconies and a lovely garden. Guests can savor free full breakfast options and enjoy on-site massage services. The welcoming atmosphere is complemented by self-parking and daily housekeeping, making it a perfect retreat for travellers.Hampton Inn Springfield-SoutheastHampton Inn Springfield-Southeast, rated 9.4 by travellers, is conveniently located just 6.6 km from Lester E. Cox Medical Center South. This hotel features an indoor pool for relaxation, as well as a fully equipped fitness centre for active travellers. Enjoy a complimentary buffet breakfast and modern amenities such as in-room refrigerators and microwaves. The hotel also offers accessible parking and cribs for added convenience.

What hotels are within walking distance to Lester E. Cox Medical Center South?

Discover ideal accommodations for your visit to Lester E. Cox Medical Center South, with a selection of top-rated hotels within walking distance that cater to your comfort and convenience.Holiday Inn Express and Suites Springfield Medical District by IHGLocated just a 15-minute walk from Lester E. Cox Medical Center South, Holiday Inn Express and Suites has a welcoming atmosphere with a review rating of 9.2. This 3-star hotel features an indoor pool, a hot tub, and a fitness centre for travellers looking to stay active. Guests can enjoy a complimentary buffet breakfast daily, and the hotel also provides free parking and early check-in options, ensuring a smooth and enjoyable stay.Candlewood Suites Springfield-Medical DistrictCandlewood Suites is a home away from home, situated 17 minutes on foot from Lester E. Cox Medical Center South. Rated 9.2 by travellers, this hotel features spacious suites equipped with full kitchens, including a refrigerator and stovetop, perfect for extended stays. Guests can also take advantage of the on-site grocery store and free self-parking, making it a convenient choice for those seeking a comfortable and flexible stay.Residence Inn by Marriott SpringfieldJust an 11-minute walk from Lester E. Cox Medical Center South, Residence Inn by Marriott Springfield boasts a review rating of 9.0 and offers a blend of comfort and convenience. This 3-star hotel features spacious suites with kitchenettes and a rooftop garden, ideal for relaxation. Guests can enjoy a complimentary full breakfast every morning, along with free self-parking and access to a fitness centre, ensuring a fulfilling stay for all.

How much is a hotel near Lester E. Cox Medical Center South?

Staying near Lester E. Cox Medical Center South is a treat, with plenty of hotels from £62 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during weekends or around public holidays.

What are the most popular family-friendly hotels near Lester E. Cox Medical Center South?

Finding the perfect family-friendly stay near Lester E. Cox Medical Center South is essential for a comfortable visit. Here are some top-rated options that cater to families looking for convenience and fun.La Quinta Inn & Suites by Wyndham Springfield SouthLa Quinta Inn & Suites by Wyndham Springfield South is a family-friendly hotel located just 4.0 km from Lester E. Cox Medical Center South. With a review rating of 8.6, this 3-star hotel offers connecting rooms, a fun indoor pool, and a complimentary buffet breakfast that's perfect for energizing the family. The hotel also features a snack bar and kids' meals in the restaurant, ensuring that dining is a breeze for families. This hotel provides a welcoming atmosphere for travellers of all ages.Comfort Inn South - SpringfieldComfort Inn South - Springfield is a superb family-friendly option situated only 2.7 km from Lester E. Cox Medical Center South. With a great traveler rating score of 8.8, this hotel features accessible indoor pools and connecting rooms to accommodate families comfortably. Guests can take advantage of the complimentary full breakfast and relax in the hot tub after a day of activities. With cribs and snack bars available, this hotel ensures a delightful stay for families exploring the area.Greenstay Inn & Suites CourtViewGreenstay Inn & Suites CourtView, located just 6.6 km from Lester E. Cox Medical Center South, is an ideal choice for families with its inviting amenities. It features kitchens equipped with dishwashers, microwaves, and cribs available at no extra cost for the little ones. Guests can enjoy a refreshing swim in the shared pool, and the hotel also offers a complimentary breakfast to start the day off right. Rated by travellers at an impressive 8.6, this hotel provides a comfortable and accommodating atmosphere for families.

What are the best affordable hotels near Lester E. Cox Medical Center South?

For those seeking budget-friendly accommodations near Lester E. Cox Medical Center South, a variety of top-rated hotels await your discovery. Here are some excellent options that combine comfort and convenience.Hampton Inn Springfield-SouthHampton Inn Springfield-South, situated only 2.9 km from Lester E. Cox Medical Center South, boasts a stellar review rating of 9.4. This hotel provides travellers with free WiFi and a delicious complimentary breakfast each morning. With an accessible pool and fitness centre, along with comfortable rooms equipped with microwaves, this hotel ensures a pleasant stay for all.Hampton Inn Springfield-SoutheastHampton Inn Springfield-Southeast is a delightful choice, located just 6.6 km from Lester E. Cox Medical Center South. Rated by travellers at an impressive 9.4, this hotel offers free WiFi and complimentary buffet breakfast daily to start your day right. Guests can enjoy the indoor pool, fitness centre, and spacious suites featuring refrigerators and microwaves for added convenience.Homewood Suites by Hilton Springfield Medical DistrictHomewood Suites by Hilton Springfield Medical District offers a blend of comfort and convenience, located within a 28-minute walk from Lester E. Cox Medical Center South. Rated at 9.4 by travellers, this 3-star hotel features spacious suites complete with kitchens, free WiFi, and daily complimentary breakfast. Guests can unwind at the indoor pool or stay active in the fitness centre, making it a reliable choice for longer stays.

Are there any hotels with pools close to Lester E. Cox Medical Center South?

Finding a relaxing hotel with a pool near Lester E. Cox Medical Center South is easy with these top-rated options in Springfield.Hampton Inn Springfield-SouthHampton Inn Springfield-South is conveniently located just 2.9 km from Lester E. Cox Medical Center South. Rated by travellers at 9.4, this hotel features an accessible outdoor pool with sun loungers, perfect for a refreshing dip. Guests enjoy complimentary buffet breakfast, daily housekeeping, and access to a fitness centre. With free self-parking and spacious suites, it's a comfortable choice for your stay.Hampton Inn Springfield-SoutheastHampton Inn Springfield-Southeast, located 6.6 km from Lester E. Cox Medical Center South, holds a strong traveler rating of 9.4. This hotel offers an inviting indoor pool with sun loungers and accessible features. Guests can enjoy a complimentary breakfast and access to a fitness centre, along with free self-parking. The spacious rooms include refrigerators and microwaves, catering to both relaxation and convenience.TownePlace Suites SpringfieldTownePlace Suites Springfield is a welcoming 3-star hotel situated 3.9 km from Lester E. Cox Medical Center South, a review rating of 9.2. This hotel features an indoor accessible pool, ideal for relaxation. Guests appreciate the free breakfast, fitness facilities available 24 hours, and well-equipped kitchenettes in the suites, making it perfect for longer stays. Additional amenities include free self-parking and a rooftop garden.

What are the best pet-friendly hotels near Lester E. Cox Medical Center South?

Discovering the best pet-friendly hotels near Lester E. Cox Medical Center South can make your stay in Springfield, Missouri, both enjoyable and accommodating for your furry friends.Bass Pro Shops Angler's LodgeBass Pro Shops Angler's Lodge is a standout option located 5.8 km from Lester E. Cox Medical Center South, with an impressive review rating of 9.0. This pet-friendly lodge welcomes your furry companions with in-room allowances and dog exercise areas. Guests can indulge in a free continental breakfast, enjoy the indoor pool and hot tub, and take advantage of 24-hour fitness facilities, ensuring a pleasant and active stay.La Quinta Inn & Suites by Wyndham Springfield SouthLa Quinta Inn & Suites by Wyndham Springfield South is a welcoming 3-star hotel located just 4.0 km from Lester E. Cox Medical Center South. With a great traveler rating score of 8.6, this hotel offers a range of pet-friendly amenities, including designated pet areas and in-room allowances for dogs and cats. Guests will appreciate the complimentary buffet breakfast, indoor pool, and fitness centre, making it a great choice for both you and your pet.Days Inn by Wyndham Battlefield Rd/Hwy 65Days Inn by Wyndham Battlefield Rd/Hwy 65, situated 6.4 km from Lester E. Cox Medical Center South, is a comfortable hotel with a review rating of 7.8. This hotel is pet-friendly, allowing pets in rooms with specific provisions. Guests can enjoy complimentary breakfast, a refreshing pool, and convenient self-parking, ensuring a straightforward stay for travellers and their pets.

Can I book a fully refundable hotel close to Lester E. Cox Medical Center South?

Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Lester E. Cox Medical Center South", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.

Search Hotels Near Lester E. Cox Medical Center South, Springfield

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Holiday Inn Express and Suites Springfield Medical District by IHG

3. Homewood Suites by Hilton Springfield Medical District

4. Candlewood Suites Springfield-Medical District

5. Element by Marriott Springfield South

6. Hilton Garden Inn Springfield, MO

7. Residence Inn by Marriott Springfield

8. La Quinta Inn & Suites by Wyndham Springfield South

9. MainStay Suites Springfield South - Battlefield Rd

10. Comfort Inn South - Springfield

11. The Bradford Hotel, an Ascend Collection Hotel

12. Sleep Inn Springfield South I60 near Medical District

13. Extended Stay America Select Suites Springfield South

14. Clarion Pointe Springfield Southeast

15. Holiday Inn Express & Suites Springfield North by IHG

16. Drury Inn & Suites Springfield, MO

17. Hampton Inn Springfield-Southeast

18. SpringHill Suites by Marriott Springfield North

19. Fairfield Inn & Suites by Marriott Springfield North

20. Hotel Vandivort

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

MainStay Suites Springfield South - Battlefield Rd

Bass Pro Shops Angler's Lodge

Holiday Inn Express and Suites Springfield Medical District by IHG

Comfort Inn South - Springfield

Sleep Inn Springfield South I60 near Medical District

Peaceful Retreat near Medical Mile in Springfield

Candlewood Suites Springfield-Medical District

Comfortable Home Near CoxHealth & MSU - Fenced Yard

Cozy Central Home by CoxHealth & MSU - Fenced Yard

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