Title: TOP Business Hotels in Southern Indiana for 2026 | Expedia.co.uk [Southern Indiana Travel Guide](https://expedia.co.uk/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.co.uk/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Holiday Rentals in Southern Indiana](https://expedia.co.uk/Southern-Indiana-Holiday-Rentals.d6059635.Travel-Guide-HolidayRentals)[Flights to Southern Indiana](https://expedia.co.uk/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Things to do in Southern Indiana](https://expedia.co.uk/Things-To-Do-In-Southern-Indiana.d6059635.Travel-Guide-Activities)[Southern Indiana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Indiana.d6059635.Car-Hire-Guide)[Southern Indiana Holidays](https://expedia.co.uk/Southern-Indiana.d6059635.Holidays-City-Breaks) ![Belle of Louisville featuring a ferry and a bay or harbour as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Southern Indiana - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Indiana Business Hotels Tonight [10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-01-10&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-01-11&endDate=2026-01-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southern Indiana business-friendly hotels ![Water park](https://images.trvl-media.com/lodging/1000000/10000/8100/8056/0ac226df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/8100/8056/24fbbddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/1000000/10000/8100/8056/80f1ebce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/8100/8056/64779169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn By Marriott Evansville East [](https://www.expedia.co.uk/Evansville-Hotels-Fairfield-Inn-By-Marriott-Evansville-East.h8056.Hotel-Information) Evansville 8.8/10 Excellent (463 reviews) "Clean rooms friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aleshia £72 includes taxes & fees 17 Jan - 18 Jan [](https://www.expedia.co.uk/Evansville-Hotels-Fairfield-Inn-By-Marriott-Evansville-East.h8056.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/930000/922000/921978/cb233b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/930000/922000/921978/52ece6ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-service breakfast on weekdays ](https://images.trvl-media.com/lodging/1000000/930000/922000/921978/9f75b601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/930000/922000/921978/074c59a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Evansville North by IHG [](https://www.expedia.co.uk/Evansville-Hotels-Holiday-Inn-Express-Suites-Evansville-North.h921978.Hotel-Information) Evansville 8.6/10 Excellent (591 reviews) "Clean room, good staff, decent breakfast, easy parking " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Phillip £82 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/Evansville-Hotels-Holiday-Inn-Express-Suites-Evansville-North.h921978.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/06213b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1,005 reviews) "Excellent place. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anatole £115 includes taxes & fees 31 Jan - 1 Feb [](https://www.expedia.co.uk/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/d5b848b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free English breakfast on weekends ](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/15aa5499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/e3cefcc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed, 2 room suite, Jetted Tub | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/d9edd5a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Madison near Clifty Falls [](https://www.expedia.co.uk/Madison-Hotels-Comfort-Inn.h869431.Hotel-Information) Madison 8.8/10 Excellent (671 reviews) "Loved our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katherine £79 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Madison-Hotels-Comfort-Inn.h869431.Hotel-Information) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/11000000/10250000/10246100/10246041/f7734028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10250000/10246100/10246041/4c4f290e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/11000000/10250000/10246100/10246041/90beda4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/11000000/10250000/10246100/10246041/50a2da6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Ferdinand [](https://www.expedia.co.uk/Jasper-Hotels-Comfort-Inn.h10246041.Hotel-Information) Ferdinand 8.4/10 Very good (606 reviews) "Enjoyed our stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randall £67 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Jasper-Hotels-Comfort-Inn.h10246041.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/15400/15372/6afca36a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/15400/15372/b100de1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/20000/15400/15372/04107d43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/15400/15372/w3833h2573x6y0-84829d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Evansville [](https://www.expedia.co.uk/Evansville-Hotels-Hampton-Inn-Evansville.h15372.Hotel-Information) Evansville 8.8/10 Excellent (1,002 reviews) "It was perfect for a quick stay and convenient to the main road and shopping" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karol £69 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Evansville-Hotels-Hampton-Inn-Evansville.h15372.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/04047b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/7f00b921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/2ac61b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, pool cabanas (surcharge)](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/162eb275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Belterra Casino Resort [](https://www.expedia.co.uk/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information) Florence 8.6/10 Excellent (1,002 reviews) " The hotel staff was excellent friendly and rooms was excellent clean,comfortable,Quite definitely a place we recommend to others." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronald £129 includes taxes & fees 13 Jan - 14 Jan [](https://www.expedia.co.uk/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/126800/126729/63837cb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/130000/126800/126729/7256b3bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/126800/126729/44369ded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Kitchenette | Room amenity](https://images.trvl-media.com/lodging/1000000/130000/126800/126729/ca9454d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garner Hotel Evansville East by IHG [](https://www.expedia.co.uk/Evansville-Hotels-Country-Inn-Suites-By-Radisson.h126729.Hotel-Information) Evansville 8.8/10 Excellent (89 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Phillip £67 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Evansville-Hotels-Country-Inn-Suites-By-Radisson.h126729.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42520000/42515500/42515492/376201e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed (Specialty) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/43000000/42520000/42515500/42515492/cf1f7a10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/43000000/42520000/42515500/42515492/d72d8b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/43000000/42520000/42515500/42515492/0ce79fbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Evansville [](https://www.expedia.co.uk/Evansville-Hotels-Hyatt-Place-Evansville.h42515492.Hotel-Information) Downtown Evansville 9.4/10 Exceptional (1,000 reviews) "Friendly staff great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jared £98 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/Evansville-Hotels-Hyatt-Place-Evansville.h42515492.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/301cfd41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking | Pillow-top beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/9454d23f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/7c4eb22a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/779a3aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Sellersburg/Louisville North [](https://www.expedia.co.uk/Sellersburg-Hotels-Ramada-By-Wyndham-SellersburgLouisville-North.h658960.Hotel-Information) Sellersburg 8.4/10 Very good (1,000 reviews) "Spotless room, easy check in, great breakfast!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen £61 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Sellersburg-Hotels-Ramada-By-Wyndham-SellersburgLouisville-North.h658960.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-24&endDate=2026-01-12®ionId=6059635&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Southern Indiana Hotel Reviews ![Drury Inn & Suites Evansville East](https://images.trvl-media.com/lodging/1000000/120000/116600/116545/2ba5f829_y.jpg) ### Drury Inn & Suites Evansville East 10/10 Excellent "Staff was incredible. Snacks and breakfast included was a huge hit with the kids (and the parents!), great variety. Will stay here again " [](https://expedia.co.uk/Evansville-Hotels-Drury-Inn-Suites-Evansville-East.h116545.Hotel-Information) ![Bally’s Evansville Casino & Hotel](https://images.trvl-media.com/lodging/1000000/70000/67500/67414/a8c75042_y.jpg) ### Bally’s Evansville Casino & Hotel 10/10 Excellent "Great staff" [](https://expedia.co.uk/Evansville-Hotels-Tropicana-Evansville-Hotel.h67414.Hotel-Information) ![Hampton Inn New Albany Louisville West](https://images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg) ### Hampton Inn New Albany Louisville West 10/10 Excellent "Didn’t get to get breakfast I slept straight through it. Rooms very clean staff was great " [](https://expedia.co.uk/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information) ![DoubleTree by Hilton Evansville](https://images.trvl-media.com/lodging/16000000/15410000/15401700/15401694/b1976648_y.jpg) ### DoubleTree by Hilton Evansville 10/10 Excellent "Didnt eat breakfast. " [](https://expedia.co.uk/Evansville-Hotels-DoubleTree-By-Hilton-Evansville.h15401694.Hotel-Information) ![One Life Studios ](https://images.trvl-media.com/lodging/1000000/20000/12200/12148/c306d08d_y.jpg) ### One Life Studios 10/10 Excellent "Loved our time so much thank you." [](https://expedia.co.uk/Evansville-Hotels-One-Life-Studios.h12148.Hotel-Information) ![Big Splash Adventure Indoor Water Park & Resort](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857069/63744e7b_y.jpg) ### Big Splash Adventure Indoor Water Park & Resort 10/10 Excellent "Yes" [](https://expedia.co.uk/French-Lick-Hotels-Big-Splash-Adventure-Indoor-Water-Park-Resort.h4857069.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Southern Indiana cost? ### How many business hotels are there in Southern Indiana? ### Why book your business hotel in Southern Indiana with Expedia? ### How can I find cheap business hotels in Southern Indiana? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Cottages in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Cottages.d6233674-aaCottages.Travel-Guide-Accommodation) - [Casino Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Casino-Hotel.0-0-d6233674-tCasinoHotel.Travel-Guide-Filter-Hotels) - 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