Title: TOP Business Hotels in Southern Indiana for 2026 | Expedia.co.uk [Southern Indiana Travel Guide](https://expedia.co.uk/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.co.uk/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Holiday Rentals in Southern Indiana](https://expedia.co.uk/Southern-Indiana-Holiday-Rentals.d6059635.Travel-Guide-HolidayRentals)[Flights to Southern Indiana](https://expedia.co.uk/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Things to do in Southern Indiana](https://expedia.co.uk/Things-To-Do-In-Southern-Indiana.d6059635.Travel-Guide-Activities)[Southern Indiana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Indiana.d6059635.Car-Hire-Guide)[Southern Indiana Holidays](https://expedia.co.uk/Southern-Indiana.d6059635.Holidays-City-Breaks) ![Belle of Louisville featuring a ferry and a bay or harbour as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Indiana Business Hotels Tonight [24 Feb - 25 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-02-24&endDate=2026-02-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [25 Feb - 26 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-02-25&endDate=2026-02-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6059635&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southern Indiana business-friendly hotels ![Bar (on property)](https://images.trvl-media.com/lodging/62000000/61410000/61401300/61401267/63e231bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/62000000/61410000/61401300/61401267/w4000h2662x0y0-8cae80e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/62000000/61410000/61401300/61401267/5bac5fac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/62000000/61410000/61401300/61401267/4694f932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Madison Historic Eagle Cotton Mill [](https://www.expedia.co.uk/Madison-Hotels-Fairfield-Inn-Suites-Madison.h61401267.Hotel-Information) Madison 9.8/10 Exceptional (402 reviews) "Beautiful hotel. Clean, friendly staff, great beds. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) shannon £115 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Madison-Hotels-Fairfield-Inn-Suites-Madison.h61401267.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/d5b848b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free English breakfast on weekends ](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/15aa5499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed, 2 room suite, Jetted Tub | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/d9edd5a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/c0a7f8fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Madison near Clifty Falls [](https://www.expedia.co.uk/Madison-Hotels-Comfort-Inn.h869431.Hotel-Information) Madison 8.8/10 Excellent (677 reviews) "Loved our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katherine £79 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Madison-Hotels-Comfort-Inn.h869431.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/04047b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/7f00b921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/2ac61b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/30bbd7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Belterra Casino Resort [](https://www.expedia.co.uk/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information) Florence 8.6/10 Excellent (1,000 reviews) "Nice room, staff curteous" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie L £121 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/116900/116863/26236ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116900/116863/d433135c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116900/116863/fd248fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/120000/116900/116863/a0ed28f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Scottsburg by IHG [](https://www.expedia.co.uk/Madison-Hotels-Holiday-Inn-Express-Suites-Scottsburg.h116863.Hotel-Information) Scottsburg 8.8/10 Excellent (678 reviews) "Great staff and accommodations. Best holiday decorations of all the holiday inns!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary £99 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Madison-Hotels-Holiday-Inn-Express-Suites-Scottsburg.h116863.Hotel-Information) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/11000000/10250000/10246100/10246041/f7734028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/11000000/10250000/10246100/10246041/90beda4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/11000000/10250000/10246100/10246041/50a2da6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/11000000/10250000/10246100/10246041/a1002c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Ferdinand [](https://www.expedia.co.uk/Jasper-Hotels-Comfort-Inn.h10246041.Hotel-Information) Ferdinand 8.4/10 Very good (621 reviews) "Good value and cost " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank £70 includes taxes & fees 11 Mar - 12 Mar [](https://www.expedia.co.uk/Jasper-Hotels-Comfort-Inn.h10246041.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/106000000/105240000/105232600/105232524/b3efde0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/106000000/105240000/105232600/105232524/1caf70dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/106000000/105240000/105232600/105232524/94303932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/106000000/105240000/105232600/105232524/298f0898.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Newburgh Evansville [](https://www.expedia.co.uk/Newburgh-Hotels-SpringHill-Suites-By-Marriott-Newburgh.h105232524.Hotel-Information) Newburgh 9.6/10 Exceptional (98 reviews) "Me and my girlfriend enjoyed our stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ben £111 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Newburgh-Hotels-SpringHill-Suites-By-Marriott-Newburgh.h105232524.Hotel-Information) ![Desk, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/900000/894200/894180/cd0f46d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King with Jetted Tub and Panoramic River View (Fireplace) | Desk, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/900000/894200/894180/7241e149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/900000/894200/894180/f8277979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/894200/894180/f09c4d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hillside Inn [](https://www.expedia.co.uk/Madison-Hotels-Hillside-Inn.h894180.Hotel-Information) Madison 8.6/10 Excellent (1,005 reviews) "Great views conveniently located staff helpful and friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alta £76 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Madison-Hotels-Hillside-Inn.h894180.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/900/838/f171539a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/900/838/6a62be2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Non Smoking King | Premium bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/900/838/ab894b7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/10000/900/838/78fc5afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jasper Inn [](https://www.expedia.co.uk/Jasper-Hotels-Jasper-Inn.h838.Hotel-Information) Jasper 8.0/10 Very good (697 reviews) "Clean, healpful staff, easy check in. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eileen £58 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Jasper-Hotels-Jasper-Inn.h838.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/126800/126729/63837cb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Kitchenette | Room amenity](https://images.trvl-media.com/lodging/1000000/130000/126800/126729/ca9454d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/126800/126729/44369ded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/130000/126800/126729/23df776e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garner Hotel Evansville East by IHG [](https://www.expedia.co.uk/Evansville-Hotels-Country-Inn-Suites-By-Radisson.h126729.Hotel-Information) Evansville 8.8/10 Excellent (103 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Phillip £64 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Evansville-Hotels-Country-Inn-Suites-By-Radisson.h126729.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/10200/10106/f2b324d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/10200/10106/7e7a5b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10200/10106/67d442e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/10200/10106/9abf0ef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Evansville/Airport [](https://www.expedia.co.uk/Evansville-Hotels-Hampton-Inn-EvansvilleAirport.h10106.Hotel-Information) Evansville 9.2/10 Wonderful (567 reviews) "Room was immaculate, pool and work out room were clean and well maintained, breakfast was delicious, and staff was helpful and kind. Lovely stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karianne £87 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Evansville-Hotels-Hampton-Inn-EvansvilleAirport.h10106.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-10&endDate=2026-03-11®ionId=6059635&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6059635) ## Top Southern Indiana Hotel Reviews ![Fairfield Inn By Marriott Evansville East](https://images.trvl-media.com/lodging/1000000/10000/8100/8056/0ac226df_y.jpg) ### Fairfield Inn By Marriott Evansville East 10/10 Excellent "Clean property, clean rooms, great free breakfast!" [](https://expedia.co.uk/Evansville-Hotels-Fairfield-Inn-By-Marriott-Evansville-East.h8056.Hotel-Information) ![Holiday Inn Express & Suites Scottsburg by IHG](https://images.trvl-media.com/lodging/1000000/120000/116900/116863/26236ff4_y.jpg) ### Holiday Inn Express & Suites Scottsburg by IHG 10/10 Excellent "This is a great stop along I-65\. The staff is very friendly and helpful, the hotel is clean, and the breakfast and coffee is good." [](https://expedia.co.uk/Madison-Hotels-Holiday-Inn-Express-Suites-Scottsburg.h116863.Hotel-Information) ![Drury Inn & Suites Evansville East](https://images.trvl-media.com/lodging/1000000/120000/116600/116545/2ba5f829_y.jpg) ### Drury Inn & Suites Evansville East 10/10 Excellent "Staff and stay were amazing!" [](https://expedia.co.uk/Evansville-Hotels-Drury-Inn-Suites-Evansville-East.h116545.Hotel-Information) ![Bally’s Evansville Casino & Hotel](https://images.trvl-media.com/lodging/1000000/70000/67500/67414/a8c75042_y.jpg) ### Bally’s Evansville Casino & Hotel 10/10 Excellent "Clean room nice bed and shower was great." [](https://expedia.co.uk/Evansville-Hotels-Tropicana-Evansville-Hotel.h67414.Hotel-Information) ![Ramada by Wyndham Sellersburg/Louisville North](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/dbc92ac1_y.jpg) ### Ramada by Wyndham Sellersburg/Louisville North 10/10 Excellent "I want to commend the team for their outstanding hospitality. The attention to detail regarding room cleanliness and guest relations made my stay incredibly productive and relaxing. I will certainly be returning on my next trip to the area." [](https://expedia.co.uk/Sellersburg-Hotels-Ramada-By-Wyndham-SellersburgLouisville-North.h658960.Hotel-Information) ![Howard Johnson by Wyndham Evansville East](https://images.trvl-media.com/lodging/1000000/20000/13800/13772/935e79b1_y.jpg) ### Howard Johnson by Wyndham Evansville East 10/10 Excellent "The color choices were absolutely abysmal. Other than that, the room was very clean. The staff was very friendly and the price was absolutely right. The buffet in the morning leaves a little bit to be desired, but once again the price was right." [](https://expedia.co.uk/Evansville-Hotels-Howard-Johnson-By-Wyndham-Evansville-East.h13772.Hotel-Information) ![Hampton Inn New Albany Louisville West](https://images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg) ### Hampton Inn New Albany Louisville West 10/10 Excellent "Clean" [](https://expedia.co.uk/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Evansville](https://images.trvl-media.com/lodging/1000000/50000/42500/42483/29ca343a_y.jpg) ### La Quinta Inn & Suites by Wyndham Evansville 10/10 Excellent "I had a very nice stay at the LaQuinta from Feb 13 thru the morning of the 15th.Staff was excellent and attentive to my needs. Only negative comment was that my room was not attended to Saturday morning by the housekeeping staff." [](https://expedia.co.uk/Evansville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Evansville.h42483.Hotel-Information) ![Sheraton Louisville Riverside by Marriott](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/14fa367c_y.jpg) ### Sheraton Louisville Riverside by Marriott 10/10 Excellent "Nice place. Restaurant attached was great too" [](https://expedia.co.uk/Louisville-Hotels-Sheraton-Louisville-Riverside-Hotel.h17862.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Southern Indiana cost? ### How many business hotels are there in Southern Indiana? ### Why book your business hotel in Southern Indiana with Expedia? ### How can I find cheap business hotels in Southern Indiana? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Cottages in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Cottages.d6233674-aaCottages.Travel-Guide-Accommodation) - [Casino Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Casino-Hotel.0-0-d6233674-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Ohio River Valley ](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Gay-Friendly-Hotel.0-0-d6233674-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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