A stone wall with a tower, palm trees, and calm water.

Find luxury hotels in Southeast Jacksonville, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Jacksonville Luxury Hotels

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Southeast Jacksonville luxury hotels

A modern restaurant with a bar area, wooden ceiling, and large windows.
A modern bar area with a central hanging light fixture, bar stools, and a well-stocked liquor display.
A modern lobby with a central seating area, wooden shelving with decorative items, and a large pillar.
A covered outdoor seating area with chairs and sofas, a fountain, and a view of a lake and trees.

1. Hilton Jacksonville at Mayo Clinic near Beaches

Hilton Jacksonville at Mayo Clinic near Beaches
Jacksonville
£145
includes taxes & fees
17 Oct - 18 Oct
Hilton Jacksonville at Mayo Clinic near Beaches
A beach view with a long stretch of sand, a pier, and a residential area with houses and a swimming pool.
A street with palm trees and a building with a sign for 'Pete's Bar'.
A room with a balcony, a sofa, a table with a vase, and a hanging light fixture.
A room with a wooden chair, a small round table with a plant, a cabinet, and a bookshelf.

2. Dune House Hotel & Spa

Dune House Hotel & Spa
Atlantic Beach
  • Beachfront elegance meets spa indulgence at this Atlantic Beach luxury hotel, where oceanfront views and full-service pampering await.
£237
includes taxes & fees
1 Nov - 2 Nov
Dune House Hotel & Spa
A hotel with a fountain, manicured gardens, and a well-lit facade.
A long dining table set for a formal meal, flanked by wine racks and elegant lighting fixtures.
A bar with a dark blue wall, ornate wooden panels, and a marble counter. There are six bar stools with patterned upholstery.
A spacious lobby with a fountain, plush seating, and decorative plants.

3. Casa Monica Resort & Spa, Autograph Collection

Casa Monica Resort & Spa, Autograph Collection
St. Augustine Historic District
  • Historic resort blends spa luxury and historic charm in the heart of St. Augustine with Mediterranean dining and poolside relaxation.
£238
includes taxes & fees
11 Nov - 12 Nov
Casa Monica Resort & Spa, Autograph Collection
A two-story building with a covered patio area featuring outdoor seating and a staircase.
A coastal residential area with a prominent blue house featuring a white porch and a brick chimney.
A large bed with a wooden frame, two bedside tables with lamps, a window with a view, and a painting on the wall.
A modern kitchen with a flat-screen TV, white cabinetry, and a dining area with a round table and two chairs.

4. Downtown Boutique Suite / On-Site Parking / ADA

Downtown Boutique Suite / On-Site Parking / ADA
St. Augustine Historic District
£168
includes taxes & fees
12 Oct - 13 Oct
Downtown Boutique Suite / On-Site Parking / ADA
A spacious living area with a grey sofa, a coffee table, and a ceiling fan.
A bedroom with a bed, a ceiling fan, a nightstand, a desk, and a painting on the wall.
A modern kitchen with white cabinets, a central island, and a dining area with blue chairs.
A hallway with a white door, a round mirror, a console table with decorative items, and a framed picture on the wall.

5. St Augustine Escape - 3-BR, WIFI, TV

St Augustine Escape - 3-BR, WIFI, TV
St Augustine
£242
includes taxes & fees
14 Oct - 15 Oct
St Augustine Escape - 3-BR, WIFI, TV
View all properties

Top Southeast Jacksonville Hotel Reviews

La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd

La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd

10/10 Excellent
"Great location, would stay again when in Jacksonville."
Christine 1-night trip
Posted 11 hours ago
La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

10/10 Excellent
"Clean room"
Scott 1-night trip
Posted 15 hours ago
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

8/10 Good
"I liked the stay. It was in a good area to the places I needed to go. Staff at the front desk were friendly. The maid was only requested once during my week stay and she didn’t clean up all the way. Made up bed and replaced towels but the room was not swept, sink and tub were NOT cleaned. They were at 100% capacity but still. Otherwise I’ll go bad. Pricewas very good."
Trent 1-night trip
Posted 15 hours ago
Wyndham Garden Jacksonville
Courtyard by Marriott Jacksonville Flagler Center

Courtyard by Marriott Jacksonville Flagler Center

10/10 Excellent
"Staff was excellent and the room was clean."
Wayne 1-night trip
Posted 15 hours ago
Courtyard by Marriott Jacksonville Flagler Center
Baymont by Wyndham Jacksonville/Butler Blvd

Baymont by Wyndham Jacksonville/Butler Blvd

10/10 Excellent
"Clean room, friendly staff, easy parking."
Lester 2-night trip
Posted 1 day ago
Baymont by Wyndham Jacksonville/Butler Blvd

Explore a world of travel with Expedia