
Santo Domingo Holidays from £1,577
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Santo Domingo Holiday
Santo Domingo is calling! Whatever type of adventure you have in mind, you can discover more of this neighbourhood with a Santo Domingo holiday package. Wondering what to see and do during your trip to Santo Domingo? Nearby attractions like Tepozteco Pyramid, El Tepozteco National Park and Pyramid and Artisan Market of Tepoztlan are excellent places to start. No matter what your ideal Santo Domingo holiday may look like, you can make it a reality with Expedia.

Casa Decu
Reviewed on 22 Jun 2026

Gran Hotel Ciudad de Mexico Zocalo View
Reviewed on 22 Jun 2026


Casa de la Luz Hotel Boutique
Reviewed on 21 Jun 2026
Where to stay in Santo Domingo

San Miguel
If you're spending some time in San Miguel, Artisan Market of Tepoztlán and Ex-Convent of the Nativity are top sights worth seeing.
Top hotels in Santo Domingo

Hotel Amomoxtli
"Todo estuvo super!!"
Reviewed on 20 Jun 2026

Hotel Zaragoza Tepoztlan
"The Spa was nice and relaxing. The staff did a good job. The only thing is that the water pressure for the shower was inconsistent. Overall a good centric place to stay if the activities are downtown."
Reviewed on 20 Oct 2025

Hostería Las Quintas Hotel
"Great stay"
Reviewed on 16 Jun 2026
Frequently asked questions
Things to do

Private Cuernavaca and Taxco Day Trip from Mexico City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.













