Santee Holidays from £966

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Your Santee Holiday

Enjoy unforgettable adventures when you book a holiday package to Santee. Whether you're a foodie, art buff or just a traveller who loves discovering new places, there's something for everyone in this lively city. If your trip to Santee includes some sightseeing, don't miss famous attractions like Santee State Park, Santee Cooper Country Club and Santee Outlets. Stop daydreaming and start travelling. Browse the many options on Expedia today and put your Santee holiday plans into action!

Top Santee Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
Seven Oaks
Price was £1,092, price is now £966 per person
£966
per person
1 Oct - 8 Oct
found 13 hours ago
Return flight included
Newcastle (NCL) to Columbia (CAE)
8.2/10 Very good! (1,111 reviews)
Great stay

Reviewed on 11 Jul 2026

Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
Price was £1,332, price is now £1,115 per person
£1,115
per person
1 Oct - 8 Oct
found 13 hours ago
Return flight included
Newcastle (NCL) to Columbia (CAE)
8.4/10 Very good! (1,005 reviews)
yes

Reviewed on 5 Jul 2026

Holiday Inn Express & Suites Columbia Downtown - The Vista by IHG

Holiday Inn Express & Suites Columbia Downtown - The Vista by IHG

2.5 out of 5
Downtown Columbia
Price was £1,709, price is now £1,452 per person
£1,452
per person
1 Oct - 8 Oct
found 13 hours ago
Return flight included
Newcastle (NCL) to Columbia (CAE)
8.8/10 Excellent! (775 reviews)
Overall the staff were very welcoming. The place was clean overall. They could just clean up the webs on the window seals. The continental breakfast pretty good both days. They could’ve just made sure the food was warmer and full. But overall it was good.

Reviewed on 9 Jul 2026

Hampton Inn Columbia-Downtown Historic District

Hampton Inn Columbia-Downtown Historic District

2.5 out of 5
Downtown Columbia
Price was £1,932, price is now £1,671 per person
£1,671
per person
1 Oct - 8 Oct
found 13 hours ago
Return flight included
Newcastle (NCL) to Columbia (CAE)
8.8/10 Excellent! (1,002 reviews)
Great location! The staff was friendly. We were moved from our original room because TV didn't work. But in the new room the fan in the bathroom was so loud we couldn't leave it on. Also the water temp was so hot in the shower and was not easy to regulate. When we turned to cold it just seemed like it was less pressure but not much different with the temperature. Good options for breakfast and overall clean. Would stay again.

Reviewed on 11 Jul 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
Price was £1,209, price is now £1,046 per person
£1,046
per person
1 Oct - 8 Oct
found 13 hours ago
Return flight included
Newcastle (NCL) to Columbia (CAE)
8.2/10 Very good! (1,011 reviews)
The room service was terrible

Reviewed on 9 Jul 2026

Santee Essential Information

Language
English
Currency
U.S dollars
Population
940
Max Temp Winter
13ºC
Max Temp Summer
32ºC
Top Sights
Santee State Park, Santee Cooper Country Club and Santee National Golf Club

Top hotels in Santee

Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
The price is £81 per night from 2 Aug to 3 Aug
£81
2 Aug - 3 Aug
includes taxes & fees
9.2/10 Wonderful! (877 reviews)
"The staff and breakfast and atmosphere was excellent and welcoming. The only down side is there weren’t any closets or dressers in the hotel room to fully settle in. Also the pool wasn’t completely clean and had some floating brown bubbles. Other than that the hotel and staff were amazing."

Reviewed on 9 Jul 2026

Tru By Hilton Santee
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
The price is £66 per night from 13 Jul to 14 Jul
£66
13 Jul - 14 Jul
includes taxes & fees
8/10 Very good! (1,480 reviews)
"Room was clean, nice and cool. I think they should add a hot breakfast. Everything else was great."

Reviewed on 10 Jul 2026

Baymont by Wyndham Santee
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
Fully refundableReserve now, pay when you stay
The price is £93 per night from 14 Jul to 15 Jul
£93
14 Jul - 15 Jul
includes taxes & fees
8.8/10 Excellent! (1,007 reviews)
"Convenient location and a comfortable stay."

Reviewed on 11 Jul 2026

Best Western Plus Santee Inn
See all 313 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Stay near popular Santee attractions

Santee State Park

8.0/10 (219 reviews)
Perched on Lake Marion's shores, Santee State Park offers unique rondette cabins built over water. Hike through cypress swamps and sinkholes while spotting alligators, fox squirrels, and diverse birdlife.
See properties

Frequently asked questions

Why should I book my Santee holiday with Expedia?
Choose Expedia to organise your next big adventure easily and all in the same place. Our insider tip for landing a great deal on a Santee retreat? Bundle your flights, hotel and/or car hire into a package holiday. Then add a couple of awesome tours and activities. Many bookings also come with flexible cancellation policies, so there's no need to stress if you have to switch up your travel agenda. Round-the-clock assistance with making tweaks to your trip is available via our Customer Service Portal link.
When is the best time of year to holiday in Santee?
Santee draws the crowds in March, April and December. If you're hoping for a more relaxed escape, head there in January, September and October. Arrange your getaway to Santee according to what style of holiday you're looking for. January is the coolest month, when average daytime temperatures are 8ºC. In July, the warmest month, you'll experience averages of 27ºC during the day.
What is the top hotel for my holiday in Santee?
Offering many of the creature comforts of home, Hampton Inn Santee-I-95 will make the ideal base for your Santee holiday.
How do I get a cheap holiday to Santee?
Combining your flight and hotel with Expedia won't just save you time — it'll save you a tidy sum too. A Santee holiday makes it a cinch to arrange the perfect trip. With more than 400 airlines all over the world to choose from, finding flights that fit your busy schedule won't be a challenge. On top of that, we have over 321,000 hotels globally to select from. Now that's what you call choice. No matter who you are, Expedia puts more of the world within your reach. Learn more about how you can save money on your holiday when you book a flight and hotel together with Expedia.
What should I do on my Santee holiday?
Make sure your next holiday in Santee is an unforgettable one by checking out its major attractions. Santee State Park, Santee Cooper Country Club, Santee Outlets and Santee National Golf Club are among the things worth discovering while you're in this city.
What is the best area to stay in when on holiday in Santee?
There's lots to explore in Santee, so stay near its best sights and allow yourself more time sightseeing. Santee State Park is one place to put on your must-see list.
Do I need a visa for my Santee holiday?
Research the latest rules on official government websites. Your nationality and whether you're visiting for study, business or leisure will determine if you'll need a visa for Santee. Get familiar with the application process, including the required documentation, turnaround times and fees. Finalise your application well in advance to allow sufficient time for processing. Some visas may take weeks or even months to go through, depending on the country.
What should I wear on my Santee holiday?
First, consider the sorts of activities you have planned during your Santee trip and bring versatile pieces that you can mix and match. For fashion inspiration or even information on dress codes, browse style blogs or social media accounts. Daytime temperatures in January, Santee's coolest month, average around 8ºC. July marks this destination's warmest month when the average daily temperature reaches 27ºC. Our top tip? Take the guesswork out of packing and check the weather forecast.
What does an Expedia Santee holiday include?
Hotels, flights and a cool set of wheels for all your road trip adventures. Simply mix and match your preferred bundle and get access to incredible deals. Once you've made your booking, add on a few sightseeing tours and watch your savings grow. When it comes to organising your Santee holiday, you're in charge! Discover a large range of property types and choose one that fits your group size and travel needs. The most popular rentals here are condos and private holiday homes. With Expedia, it's a breeze to tailor your Santee escape any way you like.
Does Expedia offer Book Now, Pay Later Santee holidays?
Yes. Expedia has joined forces with online lender Klarna to help you conveniently pay for your trip in instalments. Simply choose the payment plan best suited to your needs during the checkout process and take the stress out of budgeting for your next trip. Don't forget to bundle your accommodation, flights and car hire with Expedia to get the biggest bang for your travel buck. Browse our flexible payment options below:

  • Pay monthly holidays: Jet off on that dream holiday sooner with Klarna's manageable payment plans. If paying across multiple instalments works for you, choose this option at checkout.
  • No-deposit holidays: Pressing the "book now" button is easier with this option. With no upfront fee for your holiday, you can Book Now, Pay Later and get on your way.

Can I choose my airline with a Santee Expedia holiday?
Yes, definitely. Expedia has more than 400 airline partners to choose from worldwide. With all that choice at your fingertips, finding the right carrier to take you to Santee will be easy.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.