The Best Hotels Closest to Santee National Wildlife Refuge in Summerton - 2026 Updated Prices

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Our top choices for Santee National Wildlife Refuge hotels

A patio area with wicker furniture, a stone fire pit, and outdoor seating.

1. Fairfield Inn & Suites by Marriott Santee

4.4 mi from Santee National Wildlife Refuge

Victor

includes taxes & fees

19 Nov - 20 Nov

A Hampton Inn hotel at night with a well-lit facade and a parking lot in the foreground.

2. Hampton Inn Santee-I-95

4.4 mi from Santee National Wildlife Refuge

sandra

includes taxes & fees

13 Dec - 14 Dec

A modern lobby with a blue sofa, teal chairs, and a wooden table.

3. Tru By Hilton Santee

4.5 mi from Santee National Wildlife Refuge

Armando

includes taxes & fees

29 Nov - 30 Nov

A hotel entrance with a sign reading "Best Western PLISS."

4. Best Western Plus Santee Inn

4.4 mi from Santee National Wildlife Refuge

Johnny

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a large bed, a nightstand, a lamp, a wooden headboard, and a cityscape painting on the wall.

5. Baymont by Wyndham Santee

4.5 mi from Santee National Wildlife Refuge

Thomas

includes taxes & fees

15 Nov - 16 Nov

A Holiday Inn hotel with a covered entrance, multiple windows, and a landscaped front yard.

6. Holiday Inn Santee by IHG

4.5 mi from Santee National Wildlife Refuge

Traci

includes taxes & fees

13 Dec - 14 Dec

A living room with a sofa, armchair, coffee table, and a flat-screen TV mounted on the wall.

7. SureStay Hotel by Best Western Manning

16 mi from Santee National Wildlife Refuge

Tina

includes taxes & fees

29 Nov - 30 Nov

A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.

8. Comfort Inn & Suites Santee

4.5 mi from Santee National Wildlife Refuge

Alexis

includes taxes & fees

15 Nov - 16 Nov

9. Bells Marina & Resort

12.1 mi from Santee National Wildlife Refuge

Mark

includes taxes & fees

15 Nov - 16 Nov

A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

10. Travelodge by Wyndham Santee

4.4 mi from Santee National Wildlife Refuge

Robert

includes taxes & fees

25 Nov - 26 Nov

A two-story building with a beige facade, large windows, and a central entrance.

11. Super 8 by Wyndham Santee/I-95

4.4 mi from Santee National Wildlife Refuge

William

includes taxes & fees

19 Nov - 20 Nov

A modern room with a grey sofa, a small table, and a black countertop with a sink.

12. Starlight Stays

12.3 mi from Santee National Wildlife Refuge

tevin

includes taxes & fees

15 Nov - 16 Nov

A cabin with a porch, surrounded by trees and a body of water.

13. Red Roof Inn Santee

4.3 mi from Santee National Wildlife Refuge

Sharyn

includes taxes & fees

15 Nov - 16 Nov

A spacious living area with a wooden desk, a comfortable sofa, a fireplace, and a bookshelf.

14. Quality Inn & Suites Santee I-95

4.3 mi from Santee National Wildlife Refuge

Louis

includes taxes & fees

6 Dec - 7 Dec

A spacious lobby with a modern design, featuring a large sofa, a coffee table, and a television mounted on the wall.

15. Baymont by Wyndham Manning

15.7 mi from Santee National Wildlife Refuge

Willian

includes taxes & fees

15 Nov - 16 Nov

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

16. Econo Lodge Santee

4.4 mi from Santee National Wildlife Refuge

Arthur

includes taxes & fees

13 Dec - 14 Dec

A multi-story hotel with a covered entrance and a brick facade.

17. Best Inn of Manning

15.8 mi from Santee National Wildlife Refuge

ROLLIE

includes taxes & fees

13 Dec - 14 Dec

A room with a patterned carpet, two potted plants, a wooden shelf with books, and a door with a sign.

18. Sunset Inn Manning I 95

11.7 mi from Santee National Wildlife Refuge

James

includes taxes & fees

5 Dec - 6 Dec

A building with a large entrance, multiple windows, and potted plants in the foreground.

19. Ashburn Inn Manning I 95

11.7 mi from Santee National Wildlife Refuge

includes taxes & fees

14 Nov - 15 Nov

A spacious living area with a wooden floor, green armchairs, a dining table with chairs, a kitchen area with a bar, and ceiling fans.

20. Super 8 by Wyndham Manning

15.8 mi from Santee National Wildlife Refuge

dennis

includes taxes & fees

6 Dec - 7 Dec

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Compare popular hotels close to Santee National Wildlife Refuge

Property	Property class	Guest rating
Fairfield Inn & Suites by Marriott Santee	3.0 star property	9.8 Exceptional 1,001 reviews	View
Hampton Inn Santee-I-95	2.5 star property	9.6 Exceptional 1,001 reviews	View
Tru By Hilton Santee	2.5 star property	9.2 Wonderful 1,017 reviews	View
Best Western Plus Santee Inn	2.5 star property	8.8 Excellent 1,000 reviews	View
Baymont by Wyndham Santee	2.5 star property	8.0 Very good 1,512 reviews	View

Hotels recommended for families near Santee National Wildlife Refuge

Hampton Inn Santee-I-95

Santee

includes taxes & fees

13 Dec - 14 Dec

Top Santee National Wildlife Refuge Hotel Reviews

Fairfield Inn & Suites by Marriott Santee

10/10 Excellent

"X"

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly.

10/10 Excellent

"The inside of the home was very clean. The windows could use a cleaning. Dishes and silverware are adequate. If you plan to cook, cookware is limited to a small fry pan and one small saucepan. That being said, the Driftwood Grill Restaurant is 5 minutes away and the food and service is Excellent! The beds are comfy, but we found it odd that there was no top sheet, only the comforter/blanket. Nights were chilly, and there were no extra blankets, only a throw blanket on the living room couch. Overall, the accommodations were as described and comfy. The area is quiet, the neighbors friendly and being right on the water was lovely. We would visit again. and we enjoyed our stay"

Relax and unwind near Lake Marion - 2-bedroom 1.5 bath cabin getaway.

10/10 Excellent

"We loved our stay even thou it was only 1 night. Would have loved to have stayed a lot more. Place was exactly as described in the ad. The kitchen was well stocked with coffee,creamer,ect. Loved the oversized coffee cups! There are basic spices also in the kitchen. The place was super pet friendly. Wish we would've brought our little one."

Other attractions near Santee National Wildlife Refuge

Pine Island

Commune with nature and explore the great outdoors at Pine Island during your travels in Summerton. While you're in the area, wander around the parks.

See properties

Frequently asked questions

What's the area like around Santee National Wildlife Refuge?

Santee National Wildlife Refuge is located in a welcoming area of Summerton known for its array of dining options and golfing. You'll find 160 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Santee National Wildlife Refuge?

Tru By Hilton Santee is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located 4.5 mi (7.2 km) from Santee National Wildlife Refuge. Other good choices within a few miles include Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee.

How many hotels should I expect to find near Santee National Wildlife Refuge?

Expedia has 160 hotels and other accommodation options a few miles from Santee National Wildlife Refuge.

If I need to cancel the hotel reservation for my stay near Santee National Wildlife Refuge, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to get the best options available near Santee National Wildlife Refuge.

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Our top choices for Santee National Wildlife Refuge hotels

1. Fairfield Inn & Suites by Marriott Santee

2. Hampton Inn Santee-I-95

3. Tru By Hilton Santee

4. Best Western Plus Santee Inn

5. Baymont by Wyndham Santee

6. Holiday Inn Santee by IHG

7. SureStay Hotel by Best Western Manning

8. Comfort Inn & Suites Santee

9. Bells Marina & Resort

10. Travelodge by Wyndham Santee

11. Super 8 by Wyndham Santee/I-95

12. Starlight Stays

13. Red Roof Inn Santee

14. Quality Inn & Suites Santee I-95

15. Baymont by Wyndham Manning

16. Econo Lodge Santee

17. Best Inn of Manning

18. Sunset Inn Manning I 95

19. Ashburn Inn Manning I 95

20. Super 8 by Wyndham Manning

Compare popular hotels close to Santee National Wildlife Refuge

Hotels recommended for families near Santee National Wildlife Refuge

Hampton Inn Santee-I-95

Top Santee National Wildlife Refuge Hotel Reviews

Fairfield Inn & Suites by Marriott Santee

Other attractions near Santee National Wildlife Refuge

Pine Island

Frequently asked questions