Santee National Wildlife Refuge

Bald cypress trees with very young needles stand at the edge of Lake Marion in the Santee National Wildlife Refuge in Summerton, South Carolina.; Shutterstock ID 620988272; Purchase Order: -
Bald cypress trees with very young needles stand at the edge of Lake Marion in the Santee National Wildlife Refuge in Summerton, South Carolina.; Shutterstock ID 620988272; Purchase Order: -

Plan a trip to see Santee National Wildlife Refuge

Price found within the past 48 hours. Click for updated prices.
Executive Inn Ridgeway I-77

Executive Inn Ridgeway I-77

2.5 out of 5
Price was £778, price is now £740 per person
£740
per person
24 Apr - 27 Apr
found 1 day ago
Return direct flight included
London (LON) to Columbia (CAE)
6.8/10 (146 reviews)
The room had an empty juice bottle on the floor but the worst thing was the bugs in the room, on the floor and in the bathroom.

Reviewed on 11 Dec 2025

Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
Downtown Columbia
Price was £973, price is now £916 per person
£916
per person
24 Apr - 27 Apr
found 1 day ago
Return direct flight included
London (LON) to Columbia (CAE)
9.4/10 Exceptional! (1,003 reviews)
Genuinely nice staff

Reviewed on 30 Jan 2026

Hilton Garden Inn Columbia Downtown, SC

Hilton Garden Inn Columbia Downtown, SC

3 out of 5
Downtown Columbia
Price was £858, price is now £814 per person
£814
per person
24 Apr - 27 Apr
found 1 day ago
Return direct flight included
London (LON) to Columbia (CAE)
8/10 Very Good! (427 reviews)
everything was great

Reviewed on 26 Jan 2026

Popular places to visit

sunset with coastal landscape

Pine Island

Commune with nature and explore the great outdoors at Pine Island during your travels in Summerton. While you're in the area, wander around the parks.

Pine Island
Flying into Daybreak

Goat Island

Commune with nature and explore the great outdoors at Goat Island during your travels in Summerton. While you're in the area, wander around the parks.

Goat Island

Santee Indian Mound and Fort Watson Site

You can enjoy some culture when you stop by Santee Indian Mound and Fort Watson Site in Summerton. While you're in the area, wander around the parks.

Santee Indian Mound and Fort Watson Site

Santee State Park

You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savour the top-notch restaurants.

Santee State Park

Santee Cooper Country Club

Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savour the top-notch restaurants.

Santee Cooper Country Club

Santee National Golf Club

Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savour the top-notch restaurants.

Santee National Golf Club

Top Hotel Deals

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
Hampton Inn Santee-I-95
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

2 out of 5
Summerton SC
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
Best Western Plus Santee Inn
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd Santee SC
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy Santee SC
Travelodge by Wyndham Santee
Charming 2 Bedroom Waterfront Lake Marion Condo

Charming 2 Bedroom Waterfront Lake Marion Condo

Santee SC
Charming 2 Bedroom Waterfront Lake Marion Condo
Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

4 out of 5
401 Bass Drive Santee SC
Wyndham Vacation Resorts Lake Marion
See all 384 properties in Santee National Wildlife Refuge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.