Title: Santee National Wildlife Refuge in Summerton | Expedia.co.uk [Santee National Wildlife Refuge Hotels](https://expedia.co.uk/Santee-National-Wildlife-Refuge-Hotels.0-l553248621532654901-0.Travel-Guide-Filter-Hotels)[Flights to Summerton](https://expedia.co.uk/Cheap-Flights-To-Summerton.d163488.Travel-Guide-Flights)[Santee National Wildlife Refuge Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santee-National-Wildlife-Refuge.d553248621532654901.Car-Hire-Guide)[Summerton Holidays](https://expedia.co.uk/Summerton.d163488.Holidays-City-Breaks) # Santee National Wildlife Refuge ![Bald cypress trees with very young needles stand at the edge of Lake Marion in the Santee National Wildlife Refuge in Summerton, South Carolina.; Shutterstock ID 620988272; Purchase Order: -](https://images.trvl-media.com/place/553248621532654901/610cb34f-2808-42fe-bd56-3104903020e7.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santee National Wildlife Refuge Activities [Summerton travel guide](https://expedia.co.uk/Summerton.dx163488) --- --- ## Plan a trip to see Santee National Wildlife Refuge Price found within the past 48 hours. Click for updated prices. ![Sleep Inn Columbia](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Sleep Inn Columbia Seven Oaks £917 per person 6 May - 13 May found 19 hours ago Return flight included London (LON) to Columbia (CAE) 8.2/10 Very Good! (1,017 reviews) Was clean look a bit dated, breakfast was no good hot food content Only have 1 waffle maker, microwable sausage biscuits sandwich , instant oatmeal. Room was ok but the bathroom was really small and fell claustrophobic. Reviewed on 24 Mar 2026 ![Hampton Inn Columbia-Downtown Historic District](https://images.trvl-media.com/lodging/1000000/580000/570500/570428/ea7c920e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hampton Inn Columbia-Downtown Historic District Downtown Columbia £1,998 per person 6 May - 13 May found 19 hours ago Return flight included London (LON) to Columbia (CAE) 8.8/10 Excellent! (1,003 reviews) Excellent location- central to everything in Columbia. Our room was well appointed- we were on the first floor which gave us easy access to the lobby with minimal noise. Front desk staff were helpful and friendly. Reviewed on 23 Mar 2026 ![Hyatt Place Columbia/Downtown/The Vista](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690567/w3837h2560x3y0-ca3203e9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Place Columbia/Downtown/The Vista Downtown Columbia £1,779 per person 6 May - 13 May found 19 hours ago Return flight included London (LON) to Columbia (CAE) 8.8/10 Excellent! (1,008 reviews) The third year we have stayed here on our way down to Florida. Great hotel, great location! Reviewed on 22 Mar 2026 ### Popular places to visit ![sunset with coastal landscape](https://images.trvl-media.com/place/911206190552551424/bf4a7588-c635-4b56-8d75-7f7514d2bbd6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Pine Island Commune with nature and explore the great outdoors at Pine Island during your travels in Summerton. While you're in the area, wander around the parks. [](https://expedia.co.uk/Pine-Island-Summerton.d911206190552551424.Attraction) ![Flying into Daybreak](https://images.trvl-media.com/place/911206269963309056/33ab9600-19db-44f9-84a4-c747b6ec97d5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Goat Island Commune with nature and explore the great outdoors at Goat Island during your travels in Summerton. While you're in the area, wander around the parks. [](https://expedia.co.uk/Goat-Island-Summerton.d911206269963309056.Attraction) #### Santee Indian Mound and Fort Watson Site You can enjoy some culture when you stop by Santee Indian Mound and Fort Watson Site in Summerton. While you're in the area, wander around the parks. [](https://expedia.co.uk/Santee-Indian-Mound-And-Fort-Watson-Site-Summerton.d908645736573743104.Attraction) #### Santee State Park You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savour the top-notch restaurants. [](https://expedia.co.uk/Santee-State-Park-South-Carolina.d6140632.Attraction) #### Santee Cooper Country Club Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savour the top-notch restaurants. [](https://expedia.co.uk/Santee-Cooper-Country-Club-Santee.d553248621532654899.Attraction) #### Santee National Golf Club Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savour the top-notch restaurants. [](https://expedia.co.uk/Santee-National-Golf-Club-Santee.d553248621532654897.Attraction) --- ## Top Hotel Deals ## Check availability on hotels close to Santee National Wildlife Refuge [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532654901&startDate=2026-03-28&endDate=2026-03-29)[28 Mar - 29 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532654901&startDate=2026-03-28&endDate=2026-03-29) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532654901&startDate=2026-03-29&endDate=2026-03-30)[29 Mar - 30 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532654901&startDate=2026-03-29&endDate=2026-03-30) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532654901&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[3 Apr - 5 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532654901&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Baymont by Wyndham Santee 249 Britain Street Santee SC [](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC [](https://expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Plus Santee Inn I 95 Exit 98 Santee SC [](https://expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Santee-I-95 9060 Old Number Six Hwy Santee SC [](https://expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fairfield Inn & Suites by Marriott Santee 9074 Old Number Six Hwy Santee SC [](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6 ](https://images.trvl-media.com/lodging/109000000/108020000/108017600/108017538/f4e6785a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6 Summerton SC [](https://expedia.co.uk/Summerton-Hotels-Cozy-Lakefront-Tiny-Cabin-On-Lake-Marion-With-An-Amazing-View-And-Pet-Friendly.h108017538.Hotel-Information) ![Lake Marion in South Carolina.](https://images.trvl-media.com/lodging/78000000/77870000/77870000/77869902/w1125h750x0y8-2a70c853_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lake Marion in South Carolina. Summerton SC [](https://expedia.co.uk/Summerton-Hotels-Lake-Marion-In-South-Carolina.h77869902.Hotel-Information) ![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Santee by IHG 139 Bradford Blvd Santee SC [](https://expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Quality Inn & Suites Santee I-95](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Quality Inn & Suites Santee I-95 8929 Old Number Six Highway Santee SC [](https://expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) [See all 379 properties in Santee National Wildlife Refuge](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=553248621532654901) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.