Title: Discover the Best Hotels in Santa María Mixtequilla | 2025 Expedia.co.uk [Holiday Rentals in Santa María Mixtequilla](https://expedia.co.uk/Santa-Maria-Mixtequilla-Holiday-Rentals.d553248635640631214.Travel-Guide-HolidayRentals)[Santa María Mixtequilla Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Maria-Mixtequilla.d553248635640631214.Car-Hire-Guide)[Santa María Mixtequilla Holidays](https://expedia.co.uk/Santa-Maria-Mixtequilla.d553248635640631214.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa María Mixtequilla from £28 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa María Mixtequilla Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Mar%C3%ADa+Mixtequilla%2C+Oaxaca%2C+Mexico®ionId=553248635640631214&latLong=16.424694%2C-95.275468&adults=2&startDate=2025-12-06&d1=2025-12-06&endDate=2025-12-08&d2=2025-12-08&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Mar%C3%ADa+Mixtequilla%2C+Oaxaca%2C+Mexico®ionId=553248635640631214&latLong=16.424694%2C-95.275468&adults=2&startDate=2025-12-06&d1=2025-12-06&endDate=2025-12-08&d2=2025-12-08&travelerType=family_friendly) ## Check prices for these dates Tonight [22 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640631214&startDate=2025-11-22&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [23 Nov - 24 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640631214&startDate=2025-11-23&endDate=2025-11-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640631214&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640631214&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Santa María Mixtequilla hotels and places to stay ![Exterior](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/300fd40c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/6e2f852a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/0d8803a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/4edb454a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Santa Cruz Juchitan Juchitan de Zaragoza 7.8/10 Good (111) "Being the only hotel in town, it was fine." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tony [](https://www.expedia.co.uk/Juchitan-De-Zaragoza-Hotels-Hotel-Santa-Cruz-Juchitan.h32858642.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/50ccf9ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/fccc2483_edited_d46b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/1ff1765d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Triple Room | Bathroom | Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/c329a026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sicarú Salina Cruz 9.0/10 Wonderful (11) "Very clean, comfortable, and well located hotel in the heart of downtown Salina Cruz, Oaxaca, México. Nice price, very acceptable." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) John £34 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Salina-Cruz-Hotels-Sicaru.h116224786.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/1cd94473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/267d1cb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/920eb5b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41270000/41267200/41267126/17a71ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Calli Tehuantepec 9.0/10 Wonderful (87) "Property was nice and well maintained. Nice outside pool. Breakfast was available for a price. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angel £52 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Tehuantepec-Hotels-Hotel-Calli.h41267126.Hotel-Information) ![Superior Room, 1 Queen Bed | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/df2bb342.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/8972334d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/b8cdbcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/5799af75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### One Salina Cruz Salina Cruz 9.0/10 Wonderful (417) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Elizabeth Yazmin £54 includes taxes & fees 29 Nov - 30 Nov [](https://www.expedia.co.uk/Salina-Cruz-Hotels-One-Salina-Cruz.h6831542.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/0dc628f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/ff437264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/5d29ebb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/06b49a98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel De La Peña Inn Santa María 8.0/10 Very good (34) "Highly recommend this place for the price. Friendly professional staff. Clean room and super comfy bed. Nice bathroom. The location is a little odd being on a sort of roundabout, but as I was in town to visit the ruins of Guiengola it was ideal for me. Can't fault the plaxe " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Ralph [](https://www.expedia.co.uk/Tehuantepec-Hotels-Hotel-De-La-Pena-Inn.h33741125.Hotel-Information) ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/2a31ea42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/b23d386b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/67afa004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/904b620a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Francisco Salina Cruz 8.0/10 Very good (93) "One scorpion in the towel up my bed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariano £42 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/5fe44611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/a877e6b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/90045558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/ec7f1fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Salina Cruz Salina Cruz 8.4/10 Very good (308) "Excelente" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Yeeviani £57 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Salina-Cruz-Hotels-City-Express-Salina-Cruz.h6924397.Hotel-Information) ![40-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/103000000/102980000/102977600/102977536/0b4d9f65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/103000000/102980000/102977600/102977536/591a7b4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | 1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102980000/102977600/102977536/a8bde402.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | 1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102980000/102977600/102977536/c18138d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bungalows Punta Conejo Salina Cruz 9.2/10 Wonderful (10) "The shower had a very bad water flow. When we arrived, there were no towels and toilet-paper in the room. At the end we could almost not pay with our creditcard (raison ??) But the breakfast was very good! Thank you" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Hans £45 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Salina-Cruz-Hotels-Bungalows-Punta-Conejo.h102977536.Hotel-Information) ![Surfing/boogie boarding](https://images.trvl-media.com/lodging/13000000/12950000/12947500/12947455/e5ac6d04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12950000/12947500/12947455/544b145f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Muddy’s) | Living room | Flat-screen TV](https://images.trvl-media.com/lodging/13000000/12950000/12947500/12947455/8998baed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12950000/12947500/12947455/be02ce03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Punta Conejo Resort Salina Cruz 7.2/10 Good (12) "If you want to get off the grid and feel isolated with ocean front accommodations, this is the spot . " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Salina-Cruz-Hotels-Punta-Conejo-Resort.h12947455.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/280b2645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/33b9f057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/e0b8dcf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/575115d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Majeva Salina Cruz 10/10 Exceptional (3) "The property is truly a gem in quite a remote area. As it is a non season, everything is closed, but this hotel is working and that is nice. But actually besides its teritory there is nothing to do there. The owner is extremely nice and chatty! It gives property a lot if charm. Other staff members unfortunatelly really dont speak english much so the communication is very limited. Well, almost like in all Mexico. Overall nice pool and interior in the apartments, would be great to have some... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vismante £104 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Salina-Cruz-Hotels-Casa-Majeva.h102924009.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/f38c2e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/ca182589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/b46429cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room | Living area | 32-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/cebdc7b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Calendas Salina Cruz 7.8/10 Good (27) "The antique look and all the beautiful historical pictures" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica [](https://www.expedia.co.uk/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/e8f5e91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/51e62f1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/346b571c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/38aa9ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Central Juchitan de Zaragoza 8.6/10 Excellent (82) "Perfect hotel!" ![Belgium](https://a.travel-assets.com/egds/marks/flags/be.svg) Lukas £38 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Juchitan-De-Zaragoza-Hotels-Hotel-Central.h42090604.Hotel-Information) ![Family Twin Room | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/4cdf3a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/0ede6eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/24544c31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/16007059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Express Inn Juchitan Juchitan de Zaragoza 7.8/10 Good (19) "Ok" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) obed [](https://www.expedia.co.uk/Juchitan-De-Zaragoza-Hotels-HOTEL-EXPRESS-INN-JUCHITAN.h72665133.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/e88f7e26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/e9035ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/4c94034d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Room | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/79000000/78850000/78841500/78841413/0ea5571c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Express Inn Ixtepec Ixtepec 7.4/10 Good (54) "Express Inn is quiet , clean , and comfortable. The location is great for dining and shopping. A very fun little town " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tami [](https://www.expedia.co.uk/Ixtepec-Hotels-HOTEL-EXPRESS-INN-IXTEPEC.h78841413.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/e2ed23a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/5b276b7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/1c262942.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96050000/96041400/96041351/1aebd53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Alebrijes Salina Cruz Salina Cruz 9.4/10 Exceptional (17) "The room was clean and the housekeeping lady was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaymie £39 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Salina-Cruz-Hotels-Hotel-Boutique-Alebrijes-Salina-Cruz.h96041351.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/f7f17fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed, Non Smoking | Bathroom | Shower, rainfall showerhead, free toiletries, towels](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/025cdb79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed, Non Smoking | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/45c4b053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed, Non Smoking | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/4b8395c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de Huéspedes Juanita Salina Cruz 7.0/10 Good (16) "To rest its okay, there’s nothing to enjoy or feel surprised by the are. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juana £28 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/c7c02254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/3bec5c3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/583666f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/97000000/96180000/96177100/96177046/422306a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CASA TERESA GALERIA CAFE Juchitan de Zaragoza 7.2/10 Good (18) "Very nice owners who helped us in many ways including personally driving us to the bus station when our taxi did not arrive on time to make sure we did not miss our bus to San Cristobal." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jeffrey [](https://www.expedia.co.uk/Juchitan-De-Zaragoza-Hotels-HOTEL-CASA-TERESA-GALERIA-CAFE.h96177046.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-06&endDate=2025-12-07®ionId=553248635640631214&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_BF_PROMO_553248635640631214) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Mixtequilla-Hotels.d553248635640631214.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Mixtequilla-Hotels.d553248635640631214.Travel-Guide-Hotels) ## Top Santa María Mixtequilla Hotel Reviews ![Hotel De La Peña Inn](https://images.trvl-media.com/lodging/34000000/33750000/33741200/33741125/0dc628f7_y.jpg) ### Hotel De La Peña Inn 10/10 Excellent "Very clean. Spotless and pleasant service. " [](https://expedia.co.uk/Tehuantepec-Hotels-Hotel-De-La-Pena-Inn.h33741125.Hotel-Information) ![One Salina Cruz](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/df2bb342_y.jpg) ### One Salina Cruz 10/10 Excellent "Conveniente laundry " [](https://expedia.co.uk/Salina-Cruz-Hotels-One-Salina-Cruz.h6831542.Hotel-Information) ![City Express by Marriott Salina Cruz](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/5fe44611_y.jpg) ### City Express by Marriott Salina Cruz 10/10 Excellent "Nice" [](https://expedia.co.uk/Salina-Cruz-Hotels-City-Express-Salina-Cruz.h6924397.Hotel-Information) ![Hotel Central](https://images.trvl-media.com/lodging/43000000/42100000/42090700/42090604/e8f5e91b_y.jpg) ### Hotel Central 10/10 Excellent "It was in a great location in el Centro near the market. It was very clean and the shower was good. We enjoyed "people watching" from our balcony. During the day it was very busy outside but quiet all night until about 8am. We enjoyed having access to cold water and the aircon worked well. It was VERY hot outside." [](https://expedia.co.uk/Juchitan-De-Zaragoza-Hotels-Hotel-Central.h42090604.Hotel-Information) ![Casa Majeva](https://images.trvl-media.com/lodging/103000000/102930000/102924100/102924009/280b2645_y.jpg) ### Casa Majeva 10/10 Excellent "The property is truly a gem in quite a remote area. As it is a non season, everything is closed, but this hotel is working and that is nice. But actually besides its teritory there is nothing to do there. The owner is extremely nice and chatty! It gives property a lot if charm. Other staff members unfortunatelly really dont speak english much so the communication is very limited. Well, almost like in all Mexico. Overall nice pool and interior in the apartments, would be great to have some bedside lamps and lightening not so harsh, some “light candle” lights. " [](https://expedia.co.uk/Salina-Cruz-Hotels-Casa-Majeva.h102924009.Hotel-Information) ![Gran Hotel Don Nacho](https://images.trvl-media.com/lodging/37000000/36520000/36511300/36511274/caf80311_y.jpg) ### Gran Hotel Don Nacho 6/10 Okay "My room was plenty big, the AC unit works well. Make sure you get an extra key to keep the AC unit running, it needs a room key to work. Bed mattress was very stiff. Hotel allows people from outside to swim in the pool during the day for a few. If you are a paid guest, good luck enjoying the pool privately. " [](https://expedia.co.uk/Salina-Cruz-Hotels-GRAN-HOTEL-DON-NACHO.h36511274.Hotel-Information) ![Bungalows Punta Conejo](https://images.trvl-media.com/lodging/103000000/102980000/102977600/102977536/0b4d9f65_y.jpg) ### Bungalows Punta Conejo 10/10 Excellent "Lindo recibimiento, grandes habitaciones, buena vista, lindo restaurante, buena cocina con cariño " [](https://expedia.co.uk/Salina-Cruz-Hotels-Bungalows-Punta-Conejo.h102977536.Hotel-Information) ![Punta Conejo Resort](https://images.trvl-media.com/lodging/13000000/12950000/12947500/12947455/e5ac6d04_y.jpg) ### Punta Conejo Resort 10/10 Excellent "Loved every minute of it. It's quiet, private, the pool is wonderful. Our rooms were very clean. Thank you so much for hosting us." [](https://expedia.co.uk/Salina-Cruz-Hotels-Punta-Conejo-Resort.h12947455.Hotel-Information) ## More cheap stays in Santa María Mixtequilla ![Sicarú](https://images.trvl-media.com/lodging/117000000/116230000/116224800/116224786/50ccf9ab_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sicarú 306 Av Manuel Ávila Camacho Santa Rosa Salina Cruz Oax. £34 22 Dec - 23 Dec includes taxes & fees 8.8/10 Excellent! (10 reviews) [](https://expedia.co.uk/Salina-Cruz-Hotels-Sicaru.h116224786.Hotel-Information) ![HOTEL PENÍNSULA Salina Cruz](https://images.trvl-media.com/lodging/93000000/92550000/92544600/92544516/2ba6f043_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL PENÍNSULA Salina Cruz 25 Transístmica Lomas de Galindo Salina Cruz Oax. [Get rates](https://expedia.co.uk/Hotel-Search?startDate=06%2F12%2F2025&endDate=07%2F12%2F2025&selected=92544516&PinnedHotelID=92544516&HadPinnedHotel=true®ionId=553248635640631214) 7.2/10 Good! (9 reviews) [](https://expedia.co.uk/Salina-Cruz-Hotels-PENINSULA-STAYS-Business-Hotel.h92544516.Hotel-Information) ![Casa de Huéspedes Juanita](https://images.trvl-media.com/lodging/36000000/35260000/35253200/35253125/f7f17fd6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa de Huéspedes Juanita Tampico 80, Colonia Centro Salina Cruz OAX £28 23 Nov - 24 Nov includes taxes & fees 6.8/10 (16 reviews) [](https://expedia.co.uk/Salina-Cruz-Hotels-Casa-De-Huespedes-Juanita.h35253125.Hotel-Information) ![Hotel San Francisco](https://images.trvl-media.com/lodging/18000000/17770000/17760100/17760049/2a31ea42_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel San Francisco Av. Manuel Avila Camacho 705 Salina Cruz OAX £42 23 Nov - 24 Nov includes taxes & fees 8/10 Very Good! (93 reviews) [](https://expedia.co.uk/Salina-Cruz-Hotels-Hotel-San-Francisco.h17760049.Hotel-Information) ![Hotel Express Inn Juchitan](https://images.trvl-media.com/lodging/73000000/72670000/72665200/72665133/4cdf3a6b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Express Inn Juchitan Prolongación 16 de septiembre Juchitan de Zaragoza OAX [Get rates](https://expedia.co.uk/Hotel-Search?startDate=06%2F12%2F2025&endDate=07%2F12%2F2025&selected=72665133&PinnedHotelID=72665133&HadPinnedHotel=true®ionId=553248635640631214) 7.6/10 Good! (19 reviews) [](https://expedia.co.uk/Juchitan-De-Zaragoza-Hotels-HOTEL-EXPRESS-INN-JUCHITAN.h72665133.Hotel-Information) ![Hotel Calendas](https://images.trvl-media.com/lodging/49000000/48460000/48453300/48453285/f38c2e2b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Calendas Avenida Puerto Angel No 408 Salina Cruz OAX [Get rates](https://expedia.co.uk/Hotel-Search?startDate=06%2F12%2F2025&endDate=07%2F12%2F2025&selected=48453285&PinnedHotelID=48453285&HadPinnedHotel=true®ionId=553248635640631214) 7.8/10 Good! (27 reviews) [](https://expedia.co.uk/Salina-Cruz-Hotels-Hotel-Calendas.h48453285.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Santa María Mixtequilla? > [One Salina Cruz](https://www.expedia.co.uk/Salina-Cruz-Hotels-One-Salina-Cruz.h6831542.Hotel-Information), located 14.1 mi (22.7 km) from the heart of Santa María Mixtequilla, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are [City Express by Marriott Salina Cruz](https://www.expedia.co.uk/Salina-Cruz-Hotels-City-Express-Salina-Cruz.h6924397.Hotel-Information) and [Hotel Santa Cruz Juchitan](https://www.expedia.co.uk/Juchitan-De-Zaragoza-Hotels-Hotel-Santa-Cruz-Juchitan.h32858642.Hotel-Information). See all available [top hotels](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640631214), or [vacation rentals in Santa María Mixtequilla](https://www.expedia.co.uk/Santa-Maria-Mixtequilla-Holiday-Rentals.d553248635640631214.Travel-Guide-HolidayRentals). ### What are some of the best holiday rentals that Santa María Mixtequilla has to offer? > [House with pool a few meters from the beach come and rest!!!](https://www.expedia.co.uk/Tehuantepec-Hotels-House-With-Pool-A-Few-Meters-From-The-Beach-Come-And-Rest.h76255533.Hotel-Information): This holiday home rental outside of Santa María Mixtequilla is equipped with an outdoor pool, air conditioning and WiFi to help you feel comfortable during your stay. See all [vacation rentals in Santa María Mixtequilla](https://www.expedia.co.uk/Santa-Maria-Mixtequilla-Holiday-Rentals.d553248635640631214.Travel-Guide-HolidayRentals). ### If I need to cancel my hotel reservation in Santa María Mixtequilla, will I receive a refund? > Yes! Most hotel reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640631214&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Santa María Mixtequilla. ### What is staying in Santa María Mixtequilla like? > Travellers to Santa María Mixtequilla will find plenty to explore and enjoy. There are 23 hotels and other accommodation options in the surrounding area. Find out more about [Santa María Mixtequilla](https://www.expedia.co.uk/Santa-Maria-Mixtequilla.dx553248635640631214). ### What should I see while I'm in Santa María Mixtequilla? > Places to visit in the wider area include [Tehuantepec House of Culture](https://www.expedia.co.uk/Tehuantepec-House-Of-Culture-Tehuantepec.d6302956.Attraction), [Las Escolleras Beach](https://www.expedia.co.uk/Las-Escolleras-Beach-Mexico.d6298581.Attraction) and [Jardín Juárez](https://www.expedia.co.uk/Jardin-Juarez-Juchitan-de-Zaragoza.d553248621532976980.Attraction). You'll also find [Zocalo of Salina Cruz](https://www.expedia.co.uk/Zocalo-Of-Salina-Cruz-Salina-Cruz.d974583692942925824.Attraction) and [Salina Cruz Lighthouse](https://www.expedia.co.uk/Salina-Cruz-Lighthouse-Salina-Cruz.d6298576.Attraction) in the area. Take a look at what more there is to see and do in Expedia's [Santa María Mixtequilla guide](https://www.expedia.co.uk/Santa-Maria-Mixtequilla.dx553248635640631214). ### What's the seasonal weather in Santa María Mixtequilla? > The hottest months are usually May and April, with an average temperature of 28°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in Santa María Mixtequilla are September, June, August and July, with each month seeing an average of 191 mm of rainfall. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in Huatulco](https://www.expedia.co.uk/5Star-Huatulco-Hotels.s50-0-d553248621532629965.Travel-Guide-Filter-Hotels) - [Asuncion Ixtaltepec Hotels](https://www.expedia.co.uk/Asuncion-Ixtaltepec-Hotels.d6354376.Travel-Guide-Hotels) - [Barra de la Cruz Hotels](https://www.expedia.co.uk/Barra-De-La-Cruz-Hotels.d3000404256.Travel-Guide-Hotels) - [Hotels near Chahue Bay](https://www.expedia.co.uk/Chahue-Bay-Hotels.0-l6051928-0.Travel-Guide-Filter-Hotels) - [Chahuites Hotels](https://www.expedia.co.uk/Chahuites-Hotels.d3000434540.Travel-Guide-Hotels) - [El Espinal Hotels](https://www.expedia.co.uk/El-Espinal-Hotels.d3000458628.Travel-Guide-Hotels) - [Guevea de Humboldt Hotels](https://www.expedia.co.uk/Guevea-De-Humboldt-Hotels.d553248635640654484.Travel-Guide-Hotels) - 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(OAX) to Huatulco (HUX)](https://www.expedia.co.uk/lp/flights/oax/hux/oaxaca-intl-to-huatulco) - [Flights from Sacramento (SMF) to Huatulco (HUX)](https://www.expedia.co.uk/lp/flights/smf/hux/sacramento-to-huatulco) - [Flights from Tijuana (TIJ) to Huatulco (HUX)](https://www.expedia.co.uk/lp/flights/tij/hux/tijuana-to-huatulco) - [Flights from Toronto (YYZ) to Huatulco (HUX)](https://www.expedia.co.uk/lp/flights/yyz/hux/toronto-to-huatulco) - [Visit Asuncion Ixtaltepec](https://www.expedia.co.uk/Asuncion-Ixtaltepec.dx6354376) - [Hierve el Agua](https://www.expedia.co.uk/Hierve-El-Agua-San-Lorenzo-Albarradas.d6299841.Attraction) - [Visit Huatulco](https://www.expedia.co.uk/Huatulco.dx553248621532629965) - [Visit Juchitan de Zaragoza](https://www.expedia.co.uk/Juchitan-De-Zaragoza.dx6320272) - [La Entrega Beach](https://www.expedia.co.uk/La-Entrega-Beach-Mexico.d6075756.Attraction) - [Visit Magdalena Tequisistlán](https://www.expedia.co.uk/Magdalena-Tequisistlan.dx553248635640705341) - [Matías Romero Avendaño Holidays](https://www.expedia.co.uk/Matias-Romero-Avendano.d3000425502.Holidays-City-Breaks) - [Visit Salina Cruz](https://www.expedia.co.uk/Salina-Cruz.dx3104) - [Visit San Blas Atempa](https://www.expedia.co.uk/San-Blas-Atempa.dx553248635640638731) - [Visit San Dionisio del Mar](https://www.expedia.co.uk/San-Dionisio-Del-Mar.dx553248635640642992) - [Visit San Dionisio Ocotepec](https://www.expedia.co.uk/San-Dionisio-Ocotepec.dx553248635640694051) - [Visit San Francisco Ixhuatán](https://www.expedia.co.uk/San-Francisco-Ixhuatan.dx553248635640643406) - [Visit San Lorenzo Albarradas](https://www.expedia.co.uk/San-Lorenzo-Albarradas.dx553248635640667426) - [Visit San Miguel del Puerto](https://www.expedia.co.uk/San-Miguel-Del-Puerto.dx3000435337) - [Visit San Pedro Quiatoni](https://www.expedia.co.uk/San-Pedro-Quiatoni.dx553248635640694429) - [Visit San Pedro Tapanatepec](https://www.expedia.co.uk/San-Pedro-Tapanatepec.dx553248635640676499) - [Visit San Sebastián Río Hondo](https://www.expedia.co.uk/San-Sebastian-Rio-Hondo.dx553248635640631623) - [Visit Santa María Chimalapa](https://www.expedia.co.uk/Santa-Maria-Chimalapa.dx553248635640703042) - [Santa María Huatulco Holidays](https://www.expedia.co.uk/Santa-Maria-Huatulco.d6051926.Holidays-City-Breaks) - [Visit Santa María Huatulco](https://www.expedia.co.uk/Santa-Maria-Huatulco.dx6051926) - [Visit Santa Maria Xadani](https://www.expedia.co.uk/Santa-Maria-Xadani.dx6299486) - [Visit Santa María Zoquitlán](https://www.expedia.co.uk/Santa-Maria-Zoquitlan.dx553248635640642141) - [Visit Santiago Laollaga](https://www.expedia.co.uk/Santiago-Laollaga.dx553248635640704977) - [Visit Santiago Niltepec](https://www.expedia.co.uk/Santiago-Niltepec.dx553248635640637075) - [Visit Tamazulápam del Espíritu Santo](https://www.expedia.co.uk/Tamazulapam-Del-Espiritu-Santo.dx553248635640665159) - [Tehuantepec House of Culture](https://www.expedia.co.uk/Tehuantepec-House-Of-Culture-Tehuantepec.d6302956.Attraction) - [Visit Tehuantepec](https://www.expedia.co.uk/Tehuantepec.dx6305155) - [All inclusive Holiday Packages Huatulco](https://www.expedia.co.uk/lp/theme-holidays/all-inclusive-holidays/553248621532629965/Huatulco) - [Fishing Holiday Packages Huatulco](https://www.expedia.co.uk/lp/theme-holidays/fishing-holidays/553248621532629965/Huatulco) - [Rental cars Bahías de Huatulco Intl. airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Bahias-De-Huatulco-Intl.d6028467.Car-Hire-Guide) - [Car hire Santa María Huatulco](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Maria-Huatulco.d6051926.Car-Hire-Guide) - [Hertz Rental Cars in Huatulco](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Huatulco.d553248621532629965-c40.Car-Rental-Guide-Suppliers) - [Localiza Colombia Rental Cars in Huatulco](https://www.expedia.co.uk/Localiza-Colombia-Car-Rentals-In-Huatulco.d553248621532629965-c1029.Car-Rental-Guide-Suppliers) - [Juchitan de Zaragoza Holiday Rentals](https://www.expedia.co.uk/Juchitan-De-Zaragoza-Holiday-Rentals.d6320272.Travel-Guide-HolidayRentals) - [Things to do in San Pablo Villa de Mitla](https://www.expedia.co.uk/Things-To-Do-In-San-Pablo-Villa-De-Mitla.d6299466.Travel-Guide-Activities) - [Things to do in Santa María Huatulco](https://www.expedia.co.uk/Things-To-Do-In-Santa-Maria-Huatulco.d6051926.Travel-Guide-Activities) - [Book Hotels in Santa María Mixtequilla on Expedia.mx](https://www.expedia.mx/Santa-Maria-Mixtequilla-Hoteles.d553248635640631214.Guia-Viajes-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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