Title: Santa María Mixtequilla Holidays 2026 | Expedia.co.uk [Hotels in Santa María Mixtequilla](https://expedia.co.uk/Santa-Maria-Mixtequilla-Hotels.d553248635640631214.Travel-Guide-Hotels)[Holiday Rentals in Santa María Mixtequilla](https://expedia.co.uk/Santa-Maria-Mixtequilla-Holiday-Rentals.d553248635640631214.Travel-Guide-HolidayRentals)[Santa María Mixtequilla Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Maria-Mixtequilla.d553248635640631214.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa María Mixtequilla Holidays ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected #### Your Santa María Mixtequilla Holiday With a holiday package to Santa María Mixtequilla, say goodbye to endless planning and hello to hassle-free adventure. Every detail of your escape has been taken care of before you go, so you can spend more time experiencing this lively city. During your trip to Santa María Mixtequilla, give yourself enough time for sightseeing. A perfect place to start exploring is [Guiengola Archaeological Site](https://www.expedia.co.uk/Guiengola-Archaeological-Site-Tehuantepec.d6302936.Attraction). A couple of clicks is all it takes to put together your ideal Santa María Mixtequilla holiday on Expedia. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=PKG_SPRING_PROMO_553248635640631214) ## Santa María Mixtequilla Essential Information | Language | Spanish | | --------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | | Currency | Mexican pesos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Population | 3,600 | | Max Temp Winter | 29ºC | | Max Temp Summer | 32ºC | | Top Sights | [Guiengola Archaeological Site](https://www.expedia.co.uk/Guiengola-Archaeological-Site-Tehuantepec.d6302936.Attraction) and [Guiengola](https://www.expedia.co.uk/Guiengola-Tehuantepec.d553248621532976979.Attraction) | ## Top hotels in Santa María Mixtequilla ![One Salina Cruz](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/df2bb342_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### One Salina Cruz Carretera Transistmica No. 10 Km. 5 Salina Cruz OAX Fully refundableReserve now, pay when you stay £44 27 Feb - 28 Feb includes taxes & fees 9/10 Wonderful! (445 reviews) Room was comfortable. Good location. The breakfast was delicious. Reviewed on 10 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=27%2F02%2F2026&endDate=28%2F02%2F2026&selected=6831542&PinnedHotelID=6831542&HadPinnedHotel=true®ionId=553248635640631214) ![Hotel Santa Cruz Juchitan](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/300fd40c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Santa Cruz Juchitan Carretera Transistmica KM 818 Juchitan de Zaragoza OAX Fully refundableReserve now, pay when you stay 7.6/10 Good! (119 reviews) JAVIER, Guatemala Conveniente for One night stay. Reviewed on 16 Nov 2024 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=32858642&PinnedHotelID=32858642&HadPinnedHotel=true®ionId=553248635640631214) [](https://expedia.co.uk/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=32858642&PinnedHotelID=32858642&HadPinnedHotel=true®ionId=553248635640631214) ![City Express by Marriott Salina Cruz](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/5fe44611_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### City Express by Marriott Salina Cruz Carretera Transísmica Km. 293.9 Salina Cruz OAX Fully refundableReserve now, pay when you stay £49 23 Feb - 24 Feb includes taxes & fees 8.4/10 Very Good! (314 reviews) Nice Reviewed on 3 Jul 2025 [](https://expedia.co.uk/Hotel-Search?startDate=23%2F02%2F2026&endDate=24%2F02%2F2026&selected=6924397&PinnedHotelID=6924397&HadPinnedHotel=true®ionId=553248635640631214) [See all 23 properties in Santa María Mixtequilla](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=23%2F02%2F2026&endDate=24%2F02%2F2026®ionId=553248635640631214) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app