Santa Isabel Holidays from £695

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Top Santa Isabel Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
MARINN PLACE Financial District
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá
Las Americas Golden Tower Panama
Dreams Playa Bonita Panama - All Inclusive

Santa Isabel Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
260
Max Temp Winter
27ºC
Max Temp Summer
27ºC

Top hotels in Santa Isabel

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

2 out of 5
Diablo Island Narganá Guna Yala
10/10 Exceptional! (1 review)
Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door.

Reviewed on 15 Mar 2026

Private Ocean-Front Cabin with private bathroom on San Blas Island
Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS

3 out of 5
El Porvenir Narganá Guna Yala
Fully refundableReserve now, pay when you stay
The price is £1,617 per night from 2 May to 3 May
£1,617
2 May - 3 May
includes taxes & fees
Cocoloco - Catamaran Lagoon 52F SAN BLAS
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

Santa Isabel Colon
10/10 Exceptional! (31 reviews)
This was an incredible stay with so many lovely preparation of meals from Lucy and Jose. They were helpful and so thoughtful. We rested, relaxed, and spent leisurely days being together as a family. If only this happened more often! What a great trip. I am sad it ended so soon. Thank you to a wonderful ...

Reviewed on 1 Jan 2026

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.