Santa Isabel Holidays from £611
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Top Santa Isabel Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá
Casco Viejo
Price was £853, price is now £611 per person
£611
per person
19 Jul - 25 Jul
found 22 hours ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
7.6/10 Good! (694 reviews)
El hotel muy bonito, el trato del personal excelente. Un sólo detalle que cuando estuve se fue la luz en la ciudad casi completa y ellos no tienen generador. De lo de más todo estuvo bien.
Reviewed on 1 Jun 2026
Megapolis Hotel Panamá
San Francisco
Save 100% on your flight
Price was £2,162, price is now £1,058 per person
£1,058
per person
19 Jul - 25 Jul
found 22 hours ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
8.4/10 Very Good! (1,543 reviews)
El bufet ay muy poco personal de trabajadores para prestar un buen servicio
Reviewed on 4 Jun 2026
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was £1,609, price is now £832 per person
£832
per person
19 Jul - 25 Jul
found 22 hours ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
9.2/10 Wonderful! (1,004 reviews)
We thoroughly enjoyed our stay. Relaxing, clean and sophisticated vibe there. Central location can’t be beat. So comfortable! We liked the breakfast buffet as well. Staff was friendly. Would stay again! Very pleased :)
Reviewed on 7 Jun 2026
Riande Aeropuerto Hotel & Casino
Price was £1,063, price is now £706 per person
£706
per person
19 Jul - 25 Jul
found 22 hours ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
8.4/10 Very Good! (1,830 reviews)
Room was in need of updating but very clean and reasonable price. The property has a great pool area and restaurant on property. I had a great meal there.
Reviewed on 9 Jun 2026
Amarla Boutique Hotel Casco Viejo Adults Only
Casco Viejo
Save 100% on your flight
Price was £1,662, price is now £1,173 per person
£1,173
per person
19 Jul - 25 Jul
found 22 hours ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
9.6/10 Exceptional! (132 reviews)
Beautiful hotel, super convenient location
Reviewed on 20 Mar 2026
Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Population | 260 |
Max Temp Winter | 27ºC |
Max Temp Summer | 27ºC |
Top hotels in Santa Isabel
Caribbean Haven Of Nature 'Preci Beach'
Nombre de Dios Colon
10/10 Exceptional! (31 reviews)
Beautiful
"This place is special. The inside of the house could use a deep cleaning. But the outdoor area and beach area are incredible. We explored tide pools and snorkeled open areas and crevices all week long. Our one negative experience was fishing with some young men from the nearby town; they did not ..."
Reviewed on 17 Mar 2025
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
10/10 Exceptional! (1 review)
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door."
Reviewed on 15 Mar 2026
Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
Fully refundableReserve now, pay when you stay
The price is £1,618 per night from 17 Jun to 18 Jun
£1,618
17 Jun - 18 Jun
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
