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Our top choices for Santa Isabel hotels

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island
2.0 star property
Narganá
Private Ocean-Front Cabin with private bathroom on San Blas Island

Cabins in Asserya Island - San Blas paradise - meals included

Cabins in Asserya Island - San Blas paradise - meals included
2.0 star property
Narganá
Cabins in Asserya Island - San Blas paradise - meals included

San Blas Paradise Private Cabins on Shipwreck Island - meals included

San Blas Paradise Private Cabins on Shipwreck Island - meals included
2.0 star property
Narganá
San Blas Paradise Private Cabins on Shipwreck Island - meals included

Trips Guna Yala

Trips Guna Yala
2.0 star property
Narganá
The price is £173
includes taxes & fees
26 Feb - 27 Feb
Trips Guna Yala

Cabins on paradise San Blas island

Cabins on paradise San Blas island
2.0 star property
Narganá
Cabins on paradise San Blas island

Cabañas Isla Nubesidub San Blas

Cabañas Isla Nubesidub San Blas
2.0 star property
Narganá
Cabañas Isla Nubesidub San Blas

Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS
3.0 star property
Narganá
The price is £1,539
includes taxes & fees
10 Mar - 11 Mar
Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cabañas Nalunega San Blas

Cabañas Nalunega San Blas
2.0 star property
Narganá
Cabañas Nalunega San Blas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Isabel

Explore pristine beaches along Santa Isabel's coastline where local fishermen can take you to nearby coral reefs for snorkelling. Hike through lush rainforest trails to spot colourful birds, then visit the town's central plaza where vendors sell fresh tropical fruits and handcrafted souvenirs.

Scenic Coiba Island Aerial View

Top Santa Isabel Hotel Reviews

More cheap stays in Santa Isabel

Frequently asked questions

What is the best area to stay in Santa Isabel?
The best area to stay in Santa Isabel, Colón, Panama, is along the coastal stretch near the town centre and extending towards properties with private beach access.

This area offers direct access to the Caribbean Sea and is known for its serene environment. You'll find a selection of accommodations, from boutique hotels to more secluded resorts, typically located just off the main coastal road, providing easy access while maintaining a sense of privacy.

Couples often find this area ideal for a romantic getaway. The focus here is on relaxation and enjoying the natural beauty, with opportunities for quiet walks along the beach, swimming in the clear waters, and enjoying meals with ocean views. Some establishments offer private balconies overlooking the sea, superb for morning coffee or evening drinks.

For those looking for a luxurious and secluded experience, the properties further along the coast, offering private beach access and extensive grounds, are an excellent choice.
When is the best time to go to Santa Isabel?
The best time to visit Santa Isabel, Colón, Panama, is during the dry season, which typically runs from mid-December to mid-April. This period offers the most consistent sunshine and pleasant weather for exploring the area.

During these months, you'll experience less rainfall and lower humidity, making outdoor activities like beach visits, jungle treks, and boat trips far more enjoyable. The calm waters are also ideal for snorkelling and diving, allowing for clear views of the marine life.

Couples looking for a relaxing escape will find this time particularly appealing. The consistent good weather means you can confidently plan days by the coast or explore the natural beauty without concerns about sudden downpours. It's superb for enjoying the pristine beaches and the serene atmosphere.

Travellers interested in exploring the natural parks and engaging in outdoor adventures will also benefit from the dry season. The trails are more accessible, and wildlife spotting is often easier when the weather is clear.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Isabel.
How can I save on a Santa Isabel hotel booking with Expedia?
Members always get our best prices. Find our best Santa Isabel hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Santa Isabel hotel?
Prices for hotels in Santa Isabel often vary, but you can find a great deal from £173 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.