A tropical island with a beach, clear turquoise waters, and lush greenery.

£186 Cheap Flights to Santa Isabel

View £186 flight on Tue, 3 Nov 2026Opens in a new window

Popular airlines to Santa Isabel

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Cheap round-trip flights to Santa Isabel

Prices were available within the past 7 days and start at £186 for one-way flights and £320 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply.

Cayman Airways
Copa
United
Iberia
Air Europa

Frequently asked questions

What is the name of Santa Isabel's airport?
Book a flight to Santa Isabel and you'll be landing at Tocumen Intl. Airport (PTY).
What airport is best to fly into Santa Isabel?
With one main airport servicing Santa Isabel, it won't take you long to find the best flight. You'll be taking off to Panama Airport, which is located around 56 kms (35 miles) from the centre of town.
How many airlines fly to Santa Isabel?
There are 14 airlines connecting Santa Isabel to 83 airports across the globe.
Which airlines fly to Santa Isabel?
Copa Airlines, Avianca and Turkish Airlines fly the most frequently to Santa Isabel. The majority of these flights originate in Bogotá, with Copa Airlines having the most services on this route.
How many nonstop flights are there to Santa Isabel?
Flying to a new place is much more straightforward when there aren't any annoying stopovers to slow you down. If you're jetting off to Santa Isabel, the great news is that there are 1,346 direct flights operating each week.
Where are the most popular flights to Santa Isabel departing from?
Flights to Santa Isabel from Bogotá, San José and Miami airports are very popular.
How long is the flight to Santa Isabel Airport?
If you're going to Santa Isabel from Bogotá, you'll have a flight time of 1 hour and 50 minutes. Those jetting off from San José can expect to be in the air for 1 hour and 23 minutes. From Miami it's roughly 3 hours and 10 minutes away.
How to book the cheapest flight to Santa Isabel?
If you want to save some cash on your trip to Santa Isabel, listen up! As every seasoned traveller will tell you, avoid booking at the last minute. Fares are generally more expensive just prior to the departure date. Another easy way to nab an unbeatable deal is to shop around. If your destination has more than one airport, be sure to look into the cost of flying into a less busy terminal. And finally, remember that the early bird catches the worm. Familiarise yourself with airfare costs and have your credit card ready to grab your ticket as soon as you spot an unbeatable bargain. The sweetest deals don't last long.
Do you have any tips for my flight to Santa Isabel?
Depending on where you're coming from, your trip to Santa Isabel could be no sweat at all or it could go on forever. We've compiled some useful tips that will help you start your next big adventure on the right foot. What to pack in your hand luggage:
  • A plane trip can be a cruisy experience if you take the right gear. Firstly, you'll want some basic toiletry items, such as a toothbrush and hairbrush, a clean pair of socks and a magazine or two. Next, find room in your hand luggage for your mobile phone, a charger, your medications and maybe a neck pillow too. Lastly, be sure to bring your passport, travel papers and some money.
Do not pack the following items in your hand luggage:
  • Leave all your full-sized bottles of hair gel and hairspray in your checked luggage. Any gels or liquids in your carry-on bag larger than 3.4 ounces (100 millilitres) will be confiscated by security. Sharp objects, like your treasured Swiss Army knife, and dangerous products which are flammable or explosive, such as aerosol cans, spray paint and poisons, are also banned.
What to wear on a flight:
  • The aisles of an aircraft aren't the place for a fashion parade. Layer your clothing and choose shoes that are flat, enclosed and easy to remove.
  • Deep vein thrombosis (DVT) is a risk on long-distance flights. It results from blood clots forming due to poor circulation, so do some gentle foot and leg exercises in your seat and consider wearing compression tights or socks.
How to get through airport security fast when flying to Santa Isabel?
Being prepared before you get to the airport will help make your getaway to Santa Isabel a pleasure. We've rounded up some handy tips and tricks for a stress-free journey through security:
  • Be sure to keep your passport and boarding pass someplace easily accessible. They'll be the first things you'll be asked to show at airport security.
  • The X-ray machine is up next. Empty your pockets and remove anything metal that is likely to beep. This includes things like headphones or earphones, as well as your coat or jacket. They'll all need to go on the X-ray conveyor belt.
  • Electronic devices like phones and laptops will also have to go through the machine to be scanned. Don't worry though, you'll be back online soon enough.
  • Want to bring along your favourite perfume or cologne? Not a problem. As long as the volume is no larger than 3.4 ounces (100 millilitres) and it's stored in a clear zip-close bag, you can keep it with you on board.
  • The right choice of footwear can save you valuable minutes. Boots and heavy shoes are often required to be removed and separately scanned. Slip-on shoes are usually not.
  • Sharp items such as knives and scissors can't be taken on board. They'll be seized at security, so pack them in your checked luggage.

Book with confidence

Expedia flights to Santa Isabel

Searching for cheap flights to Santa Isabel? No travel company presents more choices than Expedia if you're looking to compare flights to Santa Isabel. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to Colón. Expedia provides the cheapest flights to many destinations in Colón and you may find even greater savings if you combine your flight with a hotel stay in Santa Isabel.

Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast.

Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to Santa Isabel for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your Santa Isabel flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price.

Expedia flights to Santa Isabel

Travel information

Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Destination city name
Panama City
Return price
£320
*Available to Expedia members.