Santa Cruz Holidays from £1,005
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Santa Cruz Holiday
Say bye-bye to the worries of planning and hello to a Santa Cruz holiday package. With your travel details organised before you go, you can focus on discovering the best of this city, starting with Tlalnepantla Centro, which is great for bars and pubs, shopping and dining. If taking in the sights is a priority during your trip to Santa Cruz, make sure you find your way to well-known attractions like Xochitla Ecological Park and Temple of San Francisco Javier. Whoever you're taking time off with and whatever the size of your budget, your dream Santa Cruz holiday is just a few clicks away with Expedia.
Top Santa Cruz Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Casa Decu
La Condesa
£1,005
per person
4 Dec - 10 Dec
found 1 day ago
Return flight included
London (LON) to Mexico City (MEX)
9.4/10 Exceptional! (1,005 reviews)
My room which is on the rooftop smells like sewer the whole stay. I'm not sure where the smell came from but it got so strong in the middle of the night to a point that it woke me up. Also the 'large double' bed is too small for two adults it's basically a full sized bed so it's inaccurate description. Location is good though and I like the outdoor seating on the balcony as well as the access to laundry.
Reviewed on 21 Sept 2026
Santa Cruz Essential Information
Language | Spanish |
|---|---|
Currency | Mexican pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Mexico City Intl. Airport (MEX) |
Population | 2,000 |
Max Temp Winter | 21ºC |
Max Temp Summer | 24ºC |
Top Sights | Xochitla Ecological Park and Temple of San Francisco Javier |
Top hotels in Santa Cruz
Hyatt Regency Mexico City
Campos Eliseos No. 204 Polanco Mexico City
Fully refundableReserve now, pay when you stay
£238
10 Oct - 11 Oct
includes taxes & fees
9.4/10 Exceptional! (1,504 reviews)
"Friny Staff."
Reviewed on 22 Sept 2026
Downtown Treasure Place
85 Marte Guerrero Mexico City CDMX
Fully refundableReserve now, pay when you stay
£31
30 Sept - 1 Oct
includes taxes & fees
8.8/10 Excellent! (900 reviews)
"staff was really nice and bathrooms really clean"
Reviewed on 21 Sept 2026
InterContinental Presidente Mexico City by IHG
Campos Eliseos 218 Mexico City
£321
10 Oct - 11 Oct
includes taxes & fees
9.4/10 Exceptional! (2,464 reviews)
"All staff very professional and very helpful. Will visit there again!!!"
Reviewed on 20 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa Cruz travel package cost?
Our Santa Cruz travel packages, which start from as low as £1,005, are the perfect way to save precious money. Handpick your preferred hotels, flights and rental car to create your ideal itinerary.
If I'm not able to travel, can I cancel my Santa Cruz travel package?
Because we know life is full of surprises, the answer is yes. To learn more, visit our Customer Service Portal. But generally speaking, if you've booked your Santa Cruz travel package in the last 24 hours, you may be able to change or cancel it for free. Your hotel, airline or car rental company may impose a fee if you made your booking a while ago.
How do I get a cheap travel package to Santa Cruz?
Track down flights that fit your schedule, add a hotel to your booking and watch the savings rack up with a Santa Cruz holiday package. It's that easy! From flights and hotels to tours and rental cars, Expedia is where your cheap holiday begins. And with more than 550 airlines and 1,000,000 properties all over the world to pick from, you won't be short of choice.
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Yes. Expedia has joined forces with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply select the payment plan that suits you best during checkout and take away the stress of budgeting for your next trip. Be sure to bundle your accommodation, car hire and flights with Expedia to get the biggest bang for your holiday buck. Take a look at our flexible payment options below:
- Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's manageable monthly instalment plans. If paying a little each month works for you, choose this option at checkout.
- Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay off your holiday across multiple transactions.
- Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to click that "book now" button, opt for a low deposit holiday payment plan from Klarna.
Where should I stay in Santa Cruz?
With interesting attractions like Temple of San Francisco Javier and Hacienda La Concepcion in this neighbourhood, try to find a hotel situated near either one. National Museum of the Viceroyalty is another Santa Cruz sight that draws the crowds.
What are the top hotels in Santa Cruz?
City Express Tepotzotlan and Puerta al Virreinato Hotel Boutique are among the most well-known hotels in Santa Cruz. Why not have a look at the facilities and amenities at each and then make up your mind?
How far in advance should I book my Santa Cruz holiday?
It's difficult to pick the best time for airfares, but we normally say the earlier, the better. Plenty of international journeys on Expedia become available to compare up to 12 months in advance. If you're booking late, don't worry. Discounted prices occasionally appear within a few weeks of departure dates.
What does an Expedia Santa Cruz travel package include?
Hotels, flights and rental cars — we've got them well covered. With Expedia, you can create your Santa Cruz package however you want. All you have to do is figure out exactly what you need. Once you've made your booking, you can add on fun things like activities and experiences. The more you bundle, the bigger the savings!
What should I know before booking a Santa Cruz travel package?
You can save big by combining your flights, hotels and rental cars. Once you've made your booking, add on fun stuff like sightseeing tours or experiences. Your next unforgettable holiday is only a few clicks away.
Can I choose my airline with a Santa Cruz Expedia travel package?
With a travel package, you're in charge. Whether you're hoping to fly to Santa Cruz in first class or coach, simply select from the available airline options. Expedia has access to over 550 partner airlines around the world.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
